• Korean Journal of Biological Psychiatry
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• v.15 no.4
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• pp.288-296
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• 2008

Objectives : We investigated the association of Val108/158Met polymorphism on catechol-O-methyl transferase(COMT) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenia patients. Methods : We measured SPEM in 217 Korean schizophrenia patients(male 116, female 101) and divided them into two groups, one was a good SPEM function group and the other was a poor SPEM function group. Then we analyzed Val108/158Met polymorphism on COMT gene. We compared the differences of genotype and allele distributions of the polymorphism on COMT gene between the two groups. Results : The natural logarithm value of signal/noise ratio(Ln S/N ratio) of the good SPEM function group was $4.39{\pm}0.33$(mean${\pm}$s.d.) and that of poor SPEM function group was $3.17{\pm}0.71$. There were no statistically significant differences of age and male/female ratio between the two groups. There were no significant differences of genotype or allele distributions of the Val108/158Met polymorphism on COMT gene between the two schizophrenic groups. Conclusions : The results suggest that Val108/158Met polymorphism on COMT gene is not related to SPEM function abnormality in schizophrenia.

• Applied Microscopy
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• v.24 no.2
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• pp.63-77
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• 1994

This experiment was performed to study the morphological responses of the epidermis of the rat scalp, following X-ray irradiation. Male rats were divided into normal and experimental groups. Rats anesthetized with sodium thiopental, were exposed only on their head areas with a single dose of 3,000rads or 6,000rads, respectively. Radiation was produced by Mitsubishi Linea Accelerator ML-4MV at the speed of 200rads/min. The target distance was 80cm. Animals were sacrificed on six hours, two days and six days following irradiation. By the perfusion fixation through the heart, rats were fixed with 1% glutaraldehyde-1% paraformaldehyde solution. Pieces of the tissue taken from the scalp were refixed in 2.5% glutaraldehyde-1.5% paraformaldehyde solution, followed by post-fixation with 1% osmium tetroxide, and embedded within araldite mixture. The sections were cut on a LKB-V ultratome, stained with uranyl acetate and lead citrate, and were observed with JEM 100CX-II electron microscope. The results were as follow; 1. Six hours after exposure to 3,000rads of X-ray. Disrupted intercellular spaces, within which some amorphous materials were filled, disrupted mitochondria, and vacuoles in the keratinocytes were frequently observed, but six days after exposure to 3,000rads of X-ray, Morphology of the keratinocytes was generally restored. 2. Many of the morphological changes were seen on the six days after exposure to 6,000rads of X-ray. 3. Widened intercellular spaces and thickened dense plaques of the desmosomes were frequently observed after exposure to 6,000rads of X-ray. 4. In the experimental groups, the Langerhans and the Merkel cells were damaged, similarly to the keratinocyte. Above results suggest that head irradiation with the dose of 3,000rads temporarily damaged the epidermis of the scalp, though most of the structures recover within six days, whereas with the dose of 6,000rads it severely damaged the epidermis without showing any recovering tendency.

• Food Science and Preservation
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• v.15 no.5
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• pp.719-724
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• 2008

The overall objectives of this study were to examine the potential of sturgeon as an intermediate moisture food (IMF) by measurement of nutritional components, such as minerals, fatty acids, amino acids, and water activity. Chemical compositions were as follows:moisture 73.2%, crude protein 19.9%, crude lipid 5.7%, ash 1.1%, and carbohydrate 0.1%. Minerals were K 317.70, P 259.88, and Mg 29.78 mg/100 g. Fatty acids detected were oleic acid (40.46% of total), palmitic acid (23.27%), and linoleic acid (15.35%). In addition, sturgeon was very rich in glutamic acid (1,189.71 mg/100 g) and deficient in serine (55.12 mg/100 g). Moisture content and water activity of sturgeon dried at $40^{\circ}C$ after soaking in different concentrationsof sugar and salt solutions were 15.12-16.24% and 0.68-0.79, respectively. Sensory evaluation of sturgeon soaked in different concentrations of sugar and salt solutions indicated that sturgeon soaked in 3.0% (w/v) sugar and salt solution scored highest.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.4
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• pp.121-131
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• 2023

PURPOSE: The purpose of this study was to evaluate the effects of ice and hot packs on proprioception, balance, and muscle strength in knee extensor muscle fatigue. METHODS: A total of 31 male and female students in their twenties from a university in A, Chungnam, Korea, were selected as participants. Three experiments were conducted to assess static balance, dynamic balance, proprioception, and muscle strength before and after induction of muscle fatigue, and following intervention. RESULTS: In the case of stability typical (ST), a significant difference was observed in pillow with eye open (PO) when a Hot pack was applied (p < .05). The weight distribution index (WDI), showed significant differences in normal eye open (NO) and Normal eye closed (NC) tests when ice packs and hot packs were applied (p < .05). In the dynamic balance assessment using Y-balance, significant differences were observed in all values except for pre- and post-intervention in the medial and lateral directions (p < .05). The recovery of proprioceptive sensation showed a significant difference when ice packs were applied (p < .05). In muscle strength, significant differences were observed in all comparisons between measurement time points (p < .05). CONCLUSION: Rest was most effective for static balance, and cold and warm compresses were most effective in recovering dynamic balance. For proprioception, cold compresses were most effective. Muscle strength had a positive effect on recovery in all three intervention methods. These results show that cold and warm compresses can be useful in the recovery of various functions related to muscle fatigue.

• Journal of Korean Physical Therapy Science
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• v.15 no.1
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• pp.67-74
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• 2008

A decrease in the ability to maintain static and dynamic balance after stroke could be related to the inability to select reliable sensory information in producing relative motor action needed to maintain postural stability. The purpose of this study was to compare the effects of two different types of surface conditions on the balancing ability of subjects with stroke. Eighteen hemiparetic subjects were assigned to an experimental and control group participating in a six－week rehabilitative therapeutic exercise program focusing on balance and mobility. Exercises were performed 3 to 5 times per week in a stable surface condition by the control group, and in an unstable surface condition by the experimental group. Pre－ and post test assessments involved the measurement of the static balance and dynamic balance, respectively by 7－item Berg Balance Scale－3P and by Pro－3 Balance System. Results showed that under the unstable surface condition, static balance in the experimental group showed more improvement than that of the control group.(Statistically, not very significant.) All the aspects of dynamic balance and mediolateral sway(balance) improved significantly than those of the control group. However, there were no significant differences between two groups. Overall, it can be concluded that under the unstable surface condition, the rehabilitative therapeutic exercise programs are effective in improving the dynamic balance of stroke subjects. The results suggest that the adaptation of the unstable surface in the rehabilitative therapeutic exercises could be effective for the patients with hemiplegia in balance. Further studies are needed to confirm the effectiveness of the unstable surface on improving balance and postural stability of hemiplegics.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.4B
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• pp.233-242
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• 2012

In the past, the domestic water supply benefit of dam has been estimated by replacement dam cost approach. But it is logically inappropriate that we use the second priority dam as a replaced facility. Therefore, this study aims to suggest the estimation method of the domestic water supply benefit by using demand function, which is deduced from Willingness-To-Pay (WTP) of consumers. For this purpose, a survey concerning the marginal WTP is carried out according to the change of water use amount used, targeted 1,000 households in metropolitan area. And by using the marginal WPT, we estimated the demand function of a family. Finally, the monthly benefit equation is derived. The approach is demonstrated and discussed for an example, the Song-Li-Won dam project which is now renamed Young-Ju dam. From the example study, the total benefit for the durable years (50 years), was about 90 billion won. The method proposed herein is expected to be practical and useful in the economic analysis of the domestic water supply project including dam construction, as well as in further studies.

• The Korean Journal of Pain
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• v.27 no.4
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• pp.326-333
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• 2014

Background: Nefopam is a centrally acting non-opioid analgesic agent. Its analgesic properties may be related to the inhibitions of monoamine reuptake and the N-methyl-D-aspartate (NMDA) receptor. The antinociceptive effect of nefopam has been shown in animal models of acute and chronic pain and in humans. However, the effect of nefopam on diabetic neuropathic pain is unclear. Therefore, we investigated the preventive effect of nefopam on diabetic neuropathic pain induced by streptozotocin (STZ) in rats. Methods: Pretreatment with nefopam (30 mg/kg) was performed intraperitoneally 30 min prior to an intraperitoneal injection of STZ (60 mg/kg). Mechanical and cold allodynia were tested before, and 1 to 4 weeks after drug administration. Thermal hyperalgesia was also investigated. In addition, the transient receptor potential ankyrin 1 (TRPA1) and TRP melastatin 8 (TRPM8) expression levels in the dorsal root ganglion (DRG) were evaluated. Results: Pretreatment with nefopam significantly inhibited STZ-induced mechanical and cold allodynia, but not thermal hyperalgesia. The STZ injection increased TRPM8, but not TRPA1, expression levels in DRG neurons. Pretreatment with nefopam decreased STZ-induced TRPM8 expression levels in the DRG. Conclusions: These results demonstrate that a nefopam pretreatment has strong antiallodynic effects on STZ-induced diabetic rats, which may be associated with TRPM8 located in the DRG.

• Journal of Korea Water Resources Association
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• v.47 no.7
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• pp.573-585
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• 2014

In this study, we propose a consensus-building support system to engage various stakeholders, transparently disseminate information, ensure objective decision-making, and reflect the view of each stakeholder as a methodology or tool for resolving conflicts that may arise in the process of implementing water environment policies and plans. The system suggests ways to resolve issues by engaging all interested actors and not just a few influential groups of stakeholders imposing their solutions upon local users. The system provides an environment where stakeholders can find solutions to conflicts through their own efforts, mediating competing interests through the interactions such as negotiations and conciliation to reach a consensus. To verify the applicability of the proposed consensus-building support system, simulated role-playing albeit restricted was conducted on the case of the Hantangang Dam construction. The simulation validated that open discussions and negotiations with the local community or NGO by the government increased the efficacy of negotiations.

• Clean Technology
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• v.9 no.4
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• pp.179-187
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• 2003

The technology of fluidized bed to use dry sorbent can be new technology that reduce the operating cost and make efficient operation. Therefore, this study investigated $CO_2$ control by dry sorbents with operating variables in a fluidized bed, compared with fixed bed for $CO_2$ adsorption capacity and pressure drop, and presented the $CO_2$ adsorption capacity of activated carbon, molecular sieve 5A, molecular sieve 13X, and activated alumina. As the results of this study, the basic data could be achieved for operation of fluidized bed process, and fluidized bed process presented relatively high $CO_2$ adsorption capacity and low pressure drop with the increase of gas velocity. In addition, molecular sieve 5A showed 1.1~3.0-fold later breakthrough point and 1.1~2.7-fold higher adsorption capacity than the other dry sorbents.

• Journal of Korean Society of Forest Science
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• v.99 no.5
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• pp.698-705
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• 2010

The concentration of monoterpenes (12 species) was measured from spring to fall in 2008 in ambient air at six different forests located in the southern parts of Korea. Sampling - using a Solid Adsorption Tube - was conducted at 2-hour-interval a day (24 hours) of each season. The highest annual average concentration of total monoterpene was 0.715 ppbv, which occurred at Mt. Baega. ${\alpha}$-Pinene, sabinene and ${\beta}$-pinene were the most abundant compounds throughout the sampling periods and areas. The concentrations of monoterpene were higher in spring than in any other seasons. The compositions and concentrations of monoterpene displayed a distinct pattern by area. Most of monoterpenes had diurnal variations with higher concentrations during the daytime, and lower during the nighttime. This may be due to the fact that the amount of monoterpenes emitted increases at elevated ambient temperatures and increased sunlight intensity. The results of this study showed that each area had distinct monoterpene compositions, which depended on the tree species, topography and local climate at each area.