• Title/Summary/Keyword: Genetic correlation

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Factors affecting the estimation of antler production in elk deer (Cervus canadensis)

  • Jeon, Dayeon;Lee, Sang-Hoon;Lee, Jinwook;Lee, Yong-Jae;Lee, Sung-Soo;Roh, Hee-Jong;Kim, Dong-Kyo;Dang, Chang-gwon;Kim, Sang-Woo;Kim, Kwan-Woo
    • Korean Journal of Agricultural Science
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    • v.46 no.3
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    • pp.497-506
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    • 2019
  • The aim of this study was to estimate the factors that can be used as a predictive indicator of antler productivity in elk. Body weight and antler data from 115 stags raised at the Animal Genetic Resources Research Center in Korea were used in this study. The function for the average antler weight was derived by age, which was $y=-3.4693+5.3747x-0.8x^2+0.0424x^3$, and $R^2$ was 0.991. The analysis of the relationship between body weight at birth and the 1st and 2nd year and the antler weight after the 2nd year showed a correlation between them. There was a correlation between the antler weight of 1 and 2 year old stags and the weight of 2 year old stags as well; especially, both antler weights for the 1st and 2nd year were highly correlated with the antler weight of the 4th year. However, there was no relationship between the antler main beam length for the 1st and 2nd year and the antler weight after the 3rd year. Therefore, it is expected that a large amount of antler will be obtained in the future if proper management is carried out for young deer from birth to 2 years old. Additionally, the results of this study are expected to be useful for the development of a deer breeding program and the deer industry.

Parenting Stress and Guilty Feeling for Mothers Having Children with Rare Genetic Metabolic Diseases (희귀유전대사질환 아동 어머니의 양육 스트레스와 죄책감)

  • Kwon, Eun Kyung;Choi, Mi Hye;Kim, Su Kang
    • Journal of Korean Clinical Nursing Research
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    • v.14 no.3
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    • pp.153-163
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    • 2008
  • Purpose: The purpose of this research, using descriptive correlation design was to identify the extent to which the mothers having children with rare genetic metabolic diseases(MPS, PWS) have parenting stress and guilt feeling. Method: This study used PSI /SF(Abidin, 1995) and Guilt Index as devised herein. From 156 mothers, data were collected from February to July 2006, using self-administered questionnaires. This study received the approval from IRB at S Hospital (IRB File No: 2006-02-014). Data were analyzed with descriptive statistics, t-test, ANOVA, and correlation. Results: Mothers felt very high level of parenting stress and sense of guilt. Parenting stress was related positively to guilt feeling. Conclusion: These findings could help understand the families of children with rare genetic metabolic diseases and those provide basic information in developing effective counseling and education programs for relief of parenting stress and guilt feeling. This study would be significant in the fact that it is the first research, targeting on the families of children with rare genetic metabolic diseases in Korea.

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Identification of Genetic Relationships Among Morus alba Genotypes Based on RAPD and ISSR Fingerprinting

  • Kalpana, Duraisamy;Cha, Hyo-Jung;Choi, Tae-Ki;Lee, Yang-Soo
    • Korean Journal of Plant Resources
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    • v.24 no.6
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    • pp.675-687
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    • 2011
  • Mulberries have importance in the sericulture industry as food for Bombyx mori, silkworm reared for its silk. Korean Morus alba have many cultivars and, for the protection of these cultivars and for utilization in plant-breeding programs, genetic information and the diversity among cultivars are essential. This study with 14 mulberry genotypes was undertaken using RAPD and ISSR fingerprinting to discover the genetic divergences between cultivars. Polymorphism rate among the cultivars produced by RAPD primer was found to be 64.48% and 66.29% relative to ISSR primer. The genetic relationships among the cultivars were identified using a dendrogram constructed with the UPGMA clustering method. Nei's method was used to calculate the genetic dissimilarity coefficients between each pair of genotypes, and the highest dissimilarity coefficient of 0.246 was exhibited between Suwon and Hwanggum cultivars. To determine the efficiency of each primer, a polymorphic index was calculated, and the robustness of the dendrogram was checked using cophenetic correlation coefficient. The results of this study can be utilized for the improvement of mulberry varieties in plant-breeding programs.

A Study on Correlation between Height Growth, Obesity and Bone maturity in Childhood (소아기에 있어 키성장과 비만도, 골성숙도와의 상관성 연구)

  • CHoi, Sang Rak;Kim, Yun Young;Jang, Eun Jin;Koo, Jin Suk
    • The Journal of Korean Medicine
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    • v.40 no.1
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    • pp.24-33
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    • 2019
  • Objectives: The purpose of this study is to analyze the causes of short stature through a clinical review of factors related to childhood height growth. So we can find the way to meet the needs of the heightism which is widely spread among modern people. Methods: Among 160 patients who came to Andong B oriental clinic for the purpose of growth therapy, 112 children whose height was smaller than other normal children were analyzed. When the children first came to the clinic, we checked their height and weight. The parents' height was recorded through a questionnaire. The relationship between obesity index and height growth was examined through growth plate test and Inbody test. We want to identify the genetic factors related to parental factors based on the data of the parent height. Results: For short stature children, weight was often normal or low. When we examined the relationship between parental genetic factors and child growth, we found that they were more influenced by father's height rather than mother's. We investigated the correlation between skeletal maturity and the five viscera. There was no apparent correlation between skeletal maturity and the five viscera but we found that there was some degree of relevance. Conclusions: For short stature children, the weight was often normal or low and parental genetic factors were more influenced by father than by mother. In the case of bone maturity it did not show a direct correlation between the five viscera.

Genetic parameters and correlations of related feed efficiency, growth, and carcass traits in Hanwoo beef cattle

  • Mehrban, Hossein;Naserkheil, Masoumeh;Lee, Deuk Hwan;Ibanez-Escriche, Noelia
    • Animal Bioscience
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    • v.34 no.5
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    • pp.824-832
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    • 2021
  • Objective: This study aimed to estimate the genetic parameters and genetic correlations for related feed efficiency, growth, and carcass traits in Hanwoo cattle. Methods: Phenotypic data from 15,279 animals born between 1989 and 2015 were considered. The related feed efficiency traits considered were Kleiber ratio (KR) and relative growth rate (RGR). Carcass traits analyzed were backfat thickness (BT), carcass weight, eye muscle area, and marbling score. Growth traits were assessed by the average daily gain (ADG), metabolic body weight (MBW) at mid-test age from 6 to 24 months, and yearling weight (YW). Variance and covariance components were estimated using restricted maximum likelihood using nine multi-trait animal models. Results: The heritability estimates for related feed efficiency (0.28±0.04 for KR and RGR) and growth traits (0.26±0.02 to 0.33±0.04) were moderate, but the carcass traits tended to be higher (0.38±0.04 to 0.61±0.06). The related feed efficiency traits were positively genetically correlated with all the carcass traits (0.37±0.09 to 0.47±0.07 for KR, and 0.14±0.09 to 0.37±0.09 for RGR), except for BT, which showed null to weak correlation. Conversely, the genetic correlations of RGR with MBW (-0.36±0.08) and YW (-0.30±0.08) were negative, and those of KR with MBW and YW were close to zero, whereas the genetic correlations of ADG with RGR (0.40±0.08) and KR (0.70±0.05) were positive and relatively moderate to high. The genetic (0.92±0.02) correlations between KR and RGR were very high. Conclusion: Sufficient genetic variability and heritability were observed for traits of interest. Moreover, the inclusion of KR and/or RGR in Hanwoo cattle breeding programs could improve the feed efficiency without producing any unfavorable effects on the carcass traits.

Cost Estimation of Case-Based Reasoning Using Hybrid Genetic Algorithm - Focusing on Local Search Method Using Correlation Analysis - (혼합형 유전자 알고리즘을 적용한 사례기반추론 공사비예측 - 상관분석을 이용한 지역탐색 기법을 중심으로 -)

  • Jung, Sangsun;Park, Moonseo;Lee, Hyun-Soo;Yoon, Inseok
    • Korean Journal of Construction Engineering and Management
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    • v.21 no.1
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    • pp.50-60
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    • 2020
  • Estimates of project costs in the early stages of a construction project have a significant impact on the operator's decision-making in important matters, such as the site's decision or the construction period. However, it is difficult to carry out the initial stage with confidence because information such as design books and specifications is not available. In previous studies, case-based reasoning was used to predict initial construction costs, and genetic algorithms were used to calculate the weight of the inquiry phase among them. However, some say that it is difficult to perform better than the current year because existing genetic algorithms are calculated in random numbers. To overcome these limitations, correlation numbers using correlation analysis rather than random numbers are reflected in the genetic algorithm by method of local search, and weights are calculated using a hybrid genetic algorithm that combines local search and genetic algorithms. A case-based reasoning model was developed using the weights calculated and validated with the data. As a result, it was found that the hybrid GA-CBR applied with local search performed better than the existing GA-CBR.

Genetic correlation between live body measurements and beef cutability traits in Hanwoo steers

  • Choy, Yun Ho;Lee, Jae Goo;Mahboob, Alam;Choi, Tae Jeong;Rho, Seung Hee
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.8
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    • pp.1074-1080
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    • 2017
  • Objective: The growth, carcass and retail cut yield records on 1,428 Hanwoo steers obtained through progeny testing were analyzed in this study, and their heritability and genetic relationships among the traits were estimated using animal models. Methods: Two different models were compared in this study. Each model was fitted for different fixed class effects, date of slaughter for carcass traits and batch of progeny test live measurement traits, and a choice of covariates (carcass weight in Model 1 or backfat thickness in Model 2) for carcass traits. Results: The differences in body composition among individuals were deemed being unaffected by their age at slaughter, except for carcass weight and backfat thickness. Heritability estimates of body size measurements were 0.21 to 0.36. Heritability estimates of retail cut percentage were high (0.56 from Model 1 and 0.47 from Model 2). And the heritability estimates for loin muscle percentage were 0.36 from Model 1 and 0.42 from Model 2, which were high enough to consider direct selection on carcass cutability traits as effective. The genetic correlations between body size measurements and retail cut ratio (RCR) were close to zero. But, some negative genetic correlations were found with chest girths measured at yearling (Model 1) or at 24 months of age or with chest widths. Loin muscle ratio (LMR) was genetically negatively correlated with body weights or body size measurements, in general in Model 1. These relationships were low close to zero but positive in Model 2. Phenotypic correlation between cutability traits (RCR, LMR) and live body size measurements were moderate and negative in Model 1 while those in Model 2 were all close to zero. Conclusion: Therefore, the body weights or linear body measurements at an earlier age may not be the most desirable selection traits for exploitation of correlated responses to improve loin muscle or lean meat yield.

A Genetic Comparison of Brucella abortus Isolates from Animals and Humans by Using the MLVA Assay

  • Her, Moon;Kang, Sung-Il;Kim, Jong-Wan;Kim, Ji-Yeon;Hwang, In-Yeong;Jung, Suk-Chan;Park, Sang-Hee;Park, Mi-Yeoun;Yoo, Han-Sang
    • Journal of Microbiology and Biotechnology
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    • v.20 no.12
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    • pp.1750-1755
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    • 2010
  • The MLVA assay is known to have a high ability to identify and discriminate Brucella species, so that it can be used as an epidemiological tool to discriminate Brucella isolates originating from restricted geographic sources. In this study, the genetic profiles of 38 B. abortus isolates from humans were analyzed and compared with genotypes from animal isolates in South Korea. As a result, it was found that they did not show high genetic diversity and were compacted. They were clustered together with animal isolates, showing a significant correlation to regional distributions. With its ability to prove a significant genetic correlation among B. abortus isolates from animals and humans in South Korea, the MLVA assay could be utilized as part of a program to control and eradicate brucellosis, one of the major zoonoses. This study represents the first data of genetic correlation of B. abortus isolates from humans and animals in South Korea.

Replication Association Study between RBC Indices and Genetic Variants in Korean Population

  • Lee, Sang In;Park, Sangjung;Jin, Hyun-Seok
    • Biomedical Science Letters
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    • v.25 no.2
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    • pp.190-195
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    • 2019
  • Hemoglobin (Hb) concentrations and hematocrit (Hct) values can be changed by factors such as erythrocyte production, destruction, and bleeding. In addition, variants in the protein expression involved in the amount of red blood cells that determine Hb metabolism or Hct value can increase susceptibility to complex blood diseases. Previous studies have reported significant single nucleotide polymorphisms (SNPs) by applying a genome-wide association study (GWAS) on Hb levels and Hct values in European population. In this study, we confirmed whether the significant SNPs are replicated in Koreans. In previous studies, 26 and 18 SNPs with a significant correlation Hb and Hct were identified in Korean genotype data, and 21 and 12 SNPs were selected, respectively. The SNPs of PRKCE (rs10495928), TMPRSS6 (rs2235321, rs5756505, rs855791) were significantly associated with Hb (P<0.05). In the association analysis of Hct, the SNPs of HBS1L (rs6920211, rs9389268, rs9483788), PRKCE (rs4953318), SCGN (rs9348689) and TMPRSS6 (rs2413450) genes showed a significant correlation (P<0.05). Replicated SNPs and not replicated SNPs showed the difference of genetic distance calculated by Fst. The replicated SNPs with a significant correlation showed similar allele frequencies, whereas the not replicated SNPs showed a large difference in allele frequency. All replicated SNPs with significant correlations had Fst values less than 0.05, indicating that the genetic distance between the groups was close. On the other hand, the not replicated SNPs showed that the Fst value was 0.05 or more and the genetic distance was relatively large.

Strength prediction and correlation of concrete by partial replacement of fly ash & silica fume

  • Kanmalai C. Williams;R. Balamuralikrishnan
    • Advances in concrete construction
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    • v.16 no.6
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    • pp.317-325
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    • 2023
  • Strength prediction and correlation of concrete is done using experimental and analytical methods. Main objective is to correlate the experimental and simulated values of compressive strength of concrete mix using Fly Ash (FA) and Silica Fume (SF) by partial replacement of cement in concrete. Mix proportion was determined using IS method for M40grade concrete. Hundred and forty-seven cubes were cast and tested using Universal Testing Machine (UTM). Genetic Algorithm (GA) model was developed using C++ program to simulate the compressive strength of concrete for various proportions of FA and SF replacements individually at 3% increments. Experiments reveal that 12 percent silica fume replacement produced maximum compressive strength of 35.5 N/mm2, 44.5 N/mm2 and 54.8 N/mm2 moreover 9 percent fly ash replacement produced a maximum strength of 31.9 N/mm2, 37.6 N/mm2 and 51.8 N/mm2 during individual material replacement of concrete mix. Correlation coefficient for each curing period of fly ash and silica fume replaced mix were acquired using trend lines. The correlation coefficient is found to be approximately 0.9 in FA and SF replaced mix irrespective of the mix proportion and age of concrete. A higher and positive correlation was found between the experimental and simulated values irrespective of the curing period in all the replacements.