• Annals of Laboratory Medicine
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• 제38권6호
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• pp.555-562
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• 2018

Background: The emerging mobile colistin resistance gene, mcr-1, is an ongoing worldwide concern and an evaluation of clinical isolates harboring this gene is required in Korea. We investigated mcr-1-possessing Enterobacteriaceae among Enterobacteriaceae strains isolated in Korea, and compared the genetic details of the plasmids with those in Escherichia coli isolates from livestock. Methods: Among 9,396 Enterobacteriaceae clinical isolates collected between 2010 and 2015, 1,347 (14.3%) strains were resistant to colistin and those were screened for mcr-1 by PCR. Colistin minimum inhibitory concentrations (MICs) were determined by microdilution, and conjugal transfer of the mcr-1-harboring plasmids was assessed by direct mating. Whole genomes of three mcr-1-positive Enterobacteriaceae clinical isolates and 11 livestock-origin mcr-1-positive E. coli isolates were sequenced. Results: Two E. coli and one Enterobacter aerogenes clinical isolates carried carried IncI2 plasmids harboring mcr-1, which conferred colistin resistance (E. coli MIC, 4 mg/L; E. aerogenes MIC, 32 mg/L). The strains possessed the complete conjugal machinery except for E. aerogenes harboring a truncated prepilin peptidase. The E. coli plasmid transferred more efficiently to E. coli than to Klebsiella pneumoniae or Enterobacter cloacae recipients. Among the three bacterial hosts, the colistin MIC was the highest for E. coli owing to the higher mcr-1-plasmid copy number and mcr-1 expression levels. Ten mcr-1-positive chicken-origin E. coli strains also possessed mcr-1-harboring IncI2 plasmids closely related to that in the clinical E. aerogenes isolate, and the remaining one porcine-origin E. coli possessed an mcr-1-harboring IncX4 plasmid. Conclusions: mcr-1-harboring IncI2 plasmids were identified in clinical Enterobacteriaceae isolates. These plasmids were closely associated with those in chicken-origin E. coli strains in Korea, supporting the concept of mcr-1 dissemination between humans and livestock.

• Journal of Chest Surgery
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• 제14권1호
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• pp.60-62
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• 1981

The Poland`s syndrome is very rare anomaly, which consists of congenital unilateral absence of the sternocostal pert of the pectoralis major muscle, with ipsilateral hand deformities. The clinical features are variable but all patients have absence of at least the sternal head of the pectoralis major muscle. The syndrome is not hereditary and is of unknown origin. Early recognition of Poland`s syndrome may give the provision of psychological and genetic counseling for anxious parents. We have encountered a patient with this entity, who showed striking paradoxical movement of the left anterior Ghest wall and recurrent pneumonia, and underwent successful surgical correction.

• 대한간호학회지
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• 제19권2호
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• pp.173-190
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• 1989

This literature review was undertaken to explore theoretical models of depression for their potential usefulness in nursing research and practice. Depression has bean accounted for by numerous theories or models of causation ; 11 theories selected from psychology, medicine and psychoanalysis and supported by empirical or experimental research were reviewed. These theories identify a variety of precipitating and predisposing factors that may affect the individual's depression. Aggression - turned - inward theory, object loss theory, ego functioning theory, personality organization theory, behavioral theory, learned helplessness theory, cognitive theory, genetic factors, and biological theories conceptualize predisposing factors. Only life stressors theory identifies precipitating facotrs. Each of these theories contributes to an understanding of depression, but many of them use overlapping and interrelated factors. It is also evident from recent. research that there are multiple causes for depression involving an interactive effect among predisposing and precipitating factors that are both biological and psychological in origin. That is, a single theory is not useful, but perhaps a unified theory could be developed that would be helpful to nursing. This review points to the need for continuing development and testing of theories that would integrate the multiple conceptualizations of depression.

• 한국작물학회지
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• 제13권
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• pp.73-76
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• 1973

Protein spectra from 6 species of Gossypium were obtained by disc electraphoresis of seed extracts. Protein extracts were made by soaking 0.5g. of seed in 15ml of Tris-glycine buffer for 24 hours. Gels 24 hours. Gels were stained in 0.5% Amido Black solution for 1 hour, and destained in 7% acetic acid for 72 hours. Nine to 15 bands were visible in each gel. Homologies of Protein bands among the species were determined by migration velocity. Evidences obtained from electrophoretic separation of seed Protein were consistent with those from genetic, cytological, morphological and Phenogenetic methods regarding the origin of New World cultivated cottons. Possibility, however, does not exist to exclude Gossypium herbaceum from one of the Progenitors of New World cultivated cottons from electrophoretic evidences alone.

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 2000년도 춘계공동학술대회 논문집
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• pp.285-288
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• 2000

본 연구는 Heuristic 알고리즘 및 유전자알고리즘(GA)을 이용하여 수거(Pickup) 및 배달(Delivery)을 동시에 고려한 통합차량운송계획 모델의 개발이다. 본 연구는 기존의 TSP의 문제를 확장 응용하였으며, 이는 한 Route에서 수거지(Origin)와 운반지(Destination)를 포함하는 수요들을 만족하도록 운반되어야 하는 문제이다. 이러한 통합차량경로계획문제(VRP Vehicle Routing Problem)를 해결하기 위한 접근방법으로 Heuristic 방법을 사용하였으며, 기존의 Saving 알고리즘과 유전자알고리즘(Genetic Algorithm)의 각종 연산자(Operators)들을 계산하여 사용한 TSP문제의 해를 본 연구의 해의 초기해로 사용하였으며 수거 및 배달문제의 특성을 고려하여 해를 구하였다. 본 연구의 결과를 다양한 운송환경에서, 거리산정방법, 가용운송장비 대수, 운송시간의 제한, 물류센터 및 운송지점의 위치 및 수요량 등 다양한 인자들을 고려한 통합시스템으로 프로그램을 개발하고 Sample 문제를 통하여 응용결과를 보였다.

• International Journal of Industrial Entomology and Biomaterials
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• 제7권1호
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• pp.69-73
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• 2003

Specific leaf weight (SLW), defined as the mass of tissue per unit leaf area has been found to be an important physiological parameter as it indicates the relative thickness of leaves. Greater SLW provides more photosynthetic potential per unit area of leaf and hence it is frequently been considered as correlated with photosynthesis in several plant species. Collections of 165 mulberry (Morus sp.) germplasm accessions, both Indian and exotic in origin were evaluated for their variability with respect to SLW. The mean specific leaf weight ranged from 35.3 to $72.3 g/m^{-2}$. The distribution of SLW was found to be normal. High heritability (97.08%) and a small difference between genotypic and phenotypic variance demonstrates the genetic control over SLW. Significant heterotic effect with respect to SLW was observed in crosses when parents with high and low SLW were chosen.

• 대한지리학회지
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• 제41권5호
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• pp.623-629
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• 2006

현재 동해의 해저지형 가운데 한국대지, 쓰시마분지, 순요퇴 3개의 지 명 이 해저지명목록집(Gazetteer)에 등재되어 있다. 이들 지명은 지명등재의 근거가 전혀 기록되어 있지 않으며, 단지 국제해도(INT 511)에 표기되어 있는 명칭이 해저지명목록집에 기록된 것으로 추정된다. 그러나 이 중 쓰시마분지와 순요퇴는 수로학적 지질학적 근거나 지리적인 관련성이 부족하므로 지리적 성인적 측면에서 관계가 깊은 울릉분지와 이사부해산으로 명칭이 대체되어야 한다.

• 건축역사연구
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• 제11권4호
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• pp.45-69
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• 2002

This study aims to find out the genetic characteristics of gridded subdivision area which has its origin from ancient local administrative city-Sangju, Jeonju, Namwon, Kwangju, Chungju. The spatial structure, based on the inter-relationship among gridded subdivision area, city wall, and topographic condition, and the morphological characteristics of gridded subdivision area are analyzed. The points of analysis on morphological characteristics of gridded subdivision area consist of the size of unit block, the organization system of unit block, the orientation of subdivision line. As a result of the analysis, three main characteristics are found. Firstly there can be found no same land subdivision rule among study areas. Secondly, the morphological features of study area were the products of cumulative process of different subdivision areas which were developed in different periods. Thirdly, the original regular gridded land subdivision seems to have been carried out in the object of a farm-land cultivation around 7th century. And there was a change of land-use from farm land to urban land-use during the later 7th century and 8th century.

• The Plant Pathology Journal
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• 제27권2호
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• pp.116-119
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• 2011

Pyrenophora graminea, the causal agent of leaf stripe disease, is an economically important pathogen of barley found worldwide. Forty-four isolates of diverse geographical origin within Syria were grouped into vegetative compatibility groups (VCGs) by demonstrating heterokaryosis by complementation tests using nitrate nonutilizing (nit) mutants. All isolates were grouped into three VCGs-1-A, 1-B and 1-C. No self-incompatibility was observed in any of the isolates tested. VCG 1-A was the most common group within growing regions in Syria and proved to be the most virulent of the VCGs identified. These data indicate that the level of virulence in P. graminea is related to VCG.

• 한국수학사학회지
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• 제33권3호
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• pp.167-177
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• 2020

Cooperative behavior may seem contrary to the notion of natural selection and adaptation, but is widely observed in nature, from the genetic level to the organism. The origin and persistence of cooperative behavior has long been a mystery to scientists studying evolution and ecology. One of the important research topics in the field of evolutionary ecology and behavioral ecology is to find out why cooperation is maintained over time. In this paper we take a historical overview of mathematical models representing cooperative relationships from the perspective of mathematical biology, which studies population dynamics between interacting biological groups, and analyze the mathematical characteristics and meanings of these cooperative models.