• Journal of Pharmaceutical Investigation
• /
• v.38 no.3
• /
• pp.207-215
• /
• 2008

Drug approval-patent linkage is the practice of linking drug marketing approval to the patent status of the originator's product and not allowing the grant of marketing approval to any third party prior to the expiration of the patent term unless by consent of the patent owner. Article 18.9.5 of Korea-US Free Trade Agreement requires that Korea introduce the linkage system in drug marketing approval. However, Korea is unfamiliar with the linkage system. In addition, there have been lots of arguments over the impacts of this system on Korean pharmaceutical industry and pharmaceutical market in the future. This report investigated the linkage systems of the US and Canada. The US and Canada have implemented drug approval-patent linkage system since 1984 and 1993, respectively. Both countries have patent lists for drug approvalpatent linkage on which originators are required to list patents on substance, product, and use of their drugs. Generic or follow-on drug applicants must contain a certification regarding each patent listed that relates to the referenced drug. If the patent holder files suit for patent infringement within 45 days of notice of application, drug approval is not allowed for several months - 30 months in the US and 24 months in Canada. Both countries have amended their systems after having experienced unexpected results such as listing improper and additional patents, multiple patent litigations and delayed generic entries. After reviewing the US and Canada's experiences, we suggested three principles needed in implementing the system: protecting patent holder's right; promoting generic drug development and marketing; monitoring the process and the effect of the system.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.1460-1464
• /
• 2003

This paper describes the design and implementation techniques of a generic Internet based telerobotic system. The purpose is to make precious technical information and hands-on experience of the authors widely available for the research community. The paper is based on the telerobotics system that the authors recently implemented between KAIST and Saga University, Japan. In its current functionality, two control modes can be exercised; high-level supervisory control, and low-level supervisory control.

• Proceedings of KOSOMES biannual meeting
• /
• 2004.05b
• /
• pp.7-11
• /
• 2004

Maritime safety and marine environmental protection are the most important topic in marine society. But, so many marine accidents rave been occurred with the development of marine transportation industry. On the other side, ship is being operated under a highly dynamic environment and many factors are related with ship's collision Nowadays, the increasing tendency to the human errors of ship's collision is remarkable, and the investigation of the human errors has been heavily concentrated. This study analysed on the human errors of ship's collision related to the negligence of lookout and classified basic error type using GEMS(Generic Error Modeling System) dynamic model.

• Nuclear Engineering and Technology
• /
• v.50 no.8
• /
• pp.1314-1323
• /
• 2018

For nuclear power plants (NPPs) to have long lifetimes, ageing is a major issue. Currently, ageing management for NPP systems is based on correlations built from generic experimental data. However, each system has its own characteristics, operational history, and environment. To account for this, it is possible to resort to prognostics that predicts the future state and time to failure (TTF) of the target system by updating the generic correlation with specific information of the target system. In this paper, we present an application of particle filtering for the prediction of degradation in steam generator tubes. With a case study, we also show how the prediction results vary depending on the uncertainty of the measurement data.

• Journal of the Korean Dietetic Association
• /
• v.9 no.3
• /
• pp.209-218
• /
• 2003

The purpose of this study was to identify obstacles by surveying dieticians' perception in implementing Generic HACCP Plan for school foodservice operations from 2001. The survey was conducted in five areas; Seoul, Kyoung-gi Province, In-cheon, Kwang-ju and Dae-jeon. Five hundred and sixty questionnaire were sent by the e-mail address and the local school dietician's Community Board on the internet, 263 were returned. Two hundred and forty were returned by E-mail, return rate was 42.86%. Twenty three were received by the local school dietician's Community Board on the internet. The obstacles were grouped of six fields and indicated thirteen factors in implementation of the Generic HACCP Plan for school foodservice. The six fields were 'status of cooperation within HACCP team', 'cooperation with the external people' such as teachers, food suppliers, student's parents, 'understanding HACCP system of the dieticians', 'hygiene facilities', 'training & educating employees', and 'difficulty of monitoring'. To assess the factor as a obstacle we used Likert's scale; 5-agree strongly, 4-agree, 3-medial, 2-don't agree, 1-don't agree strongly. Results of this study are as follows; 1) The scores of thirteen factors indicated as obstacles were over 3(medial) except ‘lack of dietician's understanding about HACCP System(2.86$\pm$0.97)'. Also only about 63% dieticians recognized that as an obstacle factor. 2) ‘Deficiency of hygiene facilities(4.41$\pm$0.76), ‘lack of teachers' cooperation(4.23$\pm$0.77)', ‘inadequacy of the kitchen lay-out(4.19$\pm$0.95)' and ‘lack of training and educating program for employees(3.97$\pm$0.85)' scored most highly. Results from this study show that financial resources and educating system are very important to settle down HACCP system for School Foodservices successfully.

• Journal of Satellite, Information and Communications
• /
• v.11 no.4
• /
• pp.89-93
• /
• 2016

In this paper, we provide a summary on the core essence of INR (Image Navigation and Registration) System technology which is an essential function of geostationary remote sensing satellites. Its origin and evolution history is reviewed, its core elements and governing concept for each element are described, and a generic INR architecture is suggested which can cover all seemingly conceivable INR systems of the past, the current and the future. By this, we intend to identify and illuminate the core technical contents and the key aspects in the foreseen prospect of the up-coming INR systems and the related technologies.

• Journal of Electrical Engineering and Technology
• /
• v.13 no.1
• /
• pp.105-113
• /
• 2018

This paper proposes pre-analysis on planning of high-voltage direct current (HVDC) transmission system applied to Korea electric power grid. HVDC transmission system for interface lines has been considered as alternative solution for high-voltage AC transmission line in South Korea since constructing new high-voltage AC transmission lines is challenging due to political, environmental and social acceptance problems. However, the installation of HVDC transmission system as interface line in AC grid must be examined carefully. Thus, this paper suggests three scenarios to examine the influences of the installation of HVDC transmission system in AC grid. The power flow and contingency analyses are carried out for the proposed scenarios. Power reserves in metro area are also evaluated. And then the transient stability analysis focusing on special protection scheme (SPS) operations is analyzed when critical lines, which are HVDC lines or high voltage AC lines, are tripped. The latest generic model of HVDC system is considered for evaluating the impacts of the SPS operations for introducing HVDC system in the AC grid. The analyses of proposed scenarios are evaluated by electromechanical simulation.

• Proceedings of the Korean Institute Of Construction Engineering and Management
• /
• autumn
• /
• pp.107-114
• /
• 2002

As many software tools are used for managing construction projects, integration of their data and information is gradually becoming critical. Focusing on the integration of design and scheduling data, a generic scheduling information model is designed through this research, with appropriate consideration for past research results on construction information model and also object oriented CAD technology. In order to test the practical usage of this model, a small prototype system which can derive schedule information from the design information is implemented.

• Bulletin of the Korean Mathematical Society
• /
• v.36 no.1
• /
• pp.147-159
• /
• 1999

Tabanov investigated the global symmetric perturbation of the integrable billiard mapping in the ellipse [3]. He showed the nonintegrability of the Birkhoff billiard in the perturbed domain by proving that the principal separatrices splitting angle is not zero.In this paper, using the exact separatrix map of an one-degree-of freedom Hamiltoniam system with time periodic perturbation, we show the existence the stochastic layer including the uniformly hyperbolic invariant set which implies the nonintegrability near the separatrices of a Birkhoff's billiard in the domain bounded by $C^2$ convex simple curve constructed by the generic global perturbation of the ellipse.

• Proceedings of the KIEE Conference
• /
• 2006.10c
• /
• pp.443-445
• /
• 2006

In this paper, we present a model-driven approach to RTOS(Real Time Operating System)-based embedded software development and an automated tool that can produce RTOS-specific code. we defined generic RTOS APIs(Application Programming Interface) that are not bound to any specific RTOS but can provide most of typical RTOS services. The generic RTOS APIs can be used as a means for describing application's RTOS-related behavior from design stage. Out tool, called Trans-PI, is able to produce specific 'C' code aimed at POSIX(Portable Operating System Interface for UNIX)-complicant RTOSs. And it is also configurable to target other RTOSs that do not conform to the POSIX standard.