• Title/Summary/Keyword: General Technology

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IL-35 Over-expression is Associated with Genesis of Gastric Cancer

  • Fan, Yong-Gang;Zhai, Jing-Ming;Wang, Wei;Feng, Bing;Yao, Guo-Liang;An, Yan-Hui;Zeng, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2845-2849
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    • 2015
  • Overexpression of interleukin (IL)-35 has been found in a variety of malignancies, but the expression status in gastric cancer has yet to be elucidated clearly. In the present study, positive expression of EBI3 and p35 was 63.3% and 70.0% of cases, respectively. EBI3 expression was strongly related with larger tumor size and invasion depth (P<0.05). Similarly, expression of p35 was also correlated with larger tumor size (P<0.05). These results indicate that IL-35 might be involved in growth of gastric cancer. Interestingly, EBI3 and p35 expressions were positive correlated with Ki-67 expression. Moreover, EBI3 immunoreactivity was associated with Bcl-2 staining. Our data suggest IL-35 is correlated with genesis of gastric cancer by regulating growth and apoptosis.

General Radiography Usage and Exposure Dose of Korean Elderly: Based on Data from Aged Patients in 2016 (한국 노인의 일반촬영 이용량 및 피폭선량: 2016년 고령환자데이터 기반)

  • Gil, Jong-Won;Yoo, Se-Jong;Lee, Won-Jeong
    • Journal of radiological science and technology
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    • v.44 no.5
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    • pp.495-502
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    • 2021
  • This study aims to provide basic data for elderly health insurance policy and medical radiation safety management by analyzing the general radiography usage and exposure dose of the elderly in Korea. The effective dose for each general radiography was calculated using the ALARA-GR program for 260 general radiography codes selected from 'National Health Insurance Care Benefit Cost'. The usage of general radiography was analyzed in the 2016 elderly patient data of the Health Insurance Review and Assessment Service, and the effective dose for each general radiography was applied. The general radiography usage and exposure dose per person aged 65 years and over was 6.47 cases and 0.56 mSv. Females showed higher value than males as 7.15 cases and 0.66 mSv(p<.001). By age, those between 75 and 79 showed the highest number as 6.97 cases and 0.62 mSv(p<.001). Those who were supported by Medical Aid showed higher value than those who were insured by National Health Insurance as 8.82 cases and 0.76 mSv(p<.001). In addition, the ratio by radiography was in the order of Chest 20.85%, Knee Joint 15.58%, and L-spine 14.67%, and the exposure dose was L-spine 29.40%, Chest 15.82%, Abdomen 7.97%, and Entire Spine 7.20%. General radiography, which is widely used due to the high frequency of diseases in the elderly population should be taken into consideration when establishing health insurance policies. In addition, it is necessary to check whether the general radiography with high exposure dose is performed as a routine examination without considering medical necessity.

A GENERAL MULTIPLE-TIME-SCALE METHOD FOR SOLVING AN n-TH ORDER WEAKLY NONLINEAR DIFFERENTIAL EQUATION WITH DAMPING

  • Azad, M. Abul Kalam;Alam, M. Shamsul;Rahman, M. Saifur;Sarker, Bimolendu Shekhar
    • Communications of the Korean Mathematical Society
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    • v.26 no.4
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    • pp.695-708
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    • 2011
  • Based on the multiple-time-scale (MTS) method, a general formula has been presented for solving an n-th, n = 2, 3, ${\ldots}$, order ordinary differential equation with strong linear damping forces. Like the solution of the unified Krylov-Bogoliubov-Mitropolskii (KBM) method or the general Struble's method, the new solution covers the un-damped, under-damped and over-damped cases. The solutions are identical to those obtained by the unified KBM method and the general Struble's method. The technique is a new form of the classical MTS method. The formulation as well as the determination of the solution from the derived formula is very simple. The method is illustrated by several examples. The general MTS solution reduces to its classical form when the real parts of eigen-values of the unperturbed equation vanish.

General Pharmacology of PEG-Hemoglobin SB1

  • Kim, Eun-Joo;Lee, Rae-Kyong;Bak, Ji-Yeong;Choi, Gyu-Kap
    • Biomolecules & Therapeutics
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    • v.7 no.2
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    • pp.170-177
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    • 1999
  • PEG-hemoglobin SB1 (SB1), which is a hemoglobin-based oxygen carrier, is intended to use as a safe blood substitute against brain ischemia and stroke. The general pharmacological profiles of SB1 were studied. The doses given were 0, 5, 10, 20 ml/kg and drugs were administered intravenously. The animals used for this study were mouse, rat and guinea pig. SB1 showed no effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital sleeping time, anticonvulsant activity, analgesic activity, blood pressure and heart rate, left ventricular peak systolic pressure, left ventricular end diastolic pressure, left ventricular developing pressure, double product, heart rate, coronary flow rate, smooth muscle contraction using guinea pig ileum, gastrointestinal transport, gastric secretion, urinary volume and electrolyte excretion at all doses tested except the decrease of body temperature. These findings demonstrated that SB1 possesses no general pharmacological effects at all doses tested.

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How does the General Public Understand Science and Technology Issues?: A Case on the Nuclear Power Issue Using Topic Modeling Approach (과학기술이슈에 대한 일반인의 인식분석: 토픽모델링을 활용한 원자력발전 사례)

  • Choi, Hyundo;Ahn, Jongwuk
    • Journal of Technology Innovation
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    • v.23 no.4
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    • pp.151-175
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    • 2015
  • The general public is a key stakeholder in the science and technology domain. However, traditional approaches require substantial efforts and resources to analyze how does the general public understand science and technology issues. We applied the topic modeling, a form of text clustering, to the texts about the nuclear power which were posted on an online space in order to explore the general public's thoughts on the issue. This study investigates the extent to which macro-level events influence understandings of the general public on the science and technology issues and weather these changes in understandings are sustained over time. It examines the possibility of applying topic modeling in narrowing a perception gap between the general public and the experts through a near-real-time monitoring of the public interests and perceptions about the science and technology issues.

Characteristics of Ion Index by Type of Land Use in Small City - Focused on Chungju (중소도시 토지이용유형별 이온지수 특성 - 충주시를 대상으로 -)

  • Kim, Jeong-Ho;Lee, Sang-Hoon;Yoon, Yong-Han
    • Journal of Environmental Science International
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    • v.27 no.7
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    • pp.489-497
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    • 2018
  • In this study, the ion index characteristics of small and medium urban land use types were investigated in the city of Chungju. The average temperature for each land use type was in the order: general commercial district ($29.59^{\circ}C$) > general residential district ($28.34^{\circ}C$) > productive green district ($28.31^{\circ}C$). The average relative humidity was in the order: productive green district (70.12%) > general residential district (69.93%) > general commercial district (66.48%). The average wind speed was in the order: productive green district (0.95 m/s) > general commercial district (0.87 m/s) > general residential district (0.54 m/s). Positive and negative ions were investigated to determine the ion index by land use type. The average amount of positive ion generated was in the order: general commercial district ($737ea/cm^3$) > general residential district ($492ea/cm^3$) > productive green district ($445ea/cm^3$). The average negative ion production decreased in the order: productive green district ($930ea/cm^3$) > general residential district ($754ea/cm^3$) > general commercial district ($744ea/cm^3$). The ion index calculated from measured data can be arranged in the order: productive green district (2.09) > general residential district (1.53) > general commercial district (1.01). These results confirm the state of positive and negative ion generation in each land use type. Further, the differences in the ion index by land use type were confirmed. However, a limitation of this study is that simple summer measurements were conducted, and seasonal characteristics were not considered. Therefore, any future investigation and research should consider seasonal variation characteristics.

Speculative Parallelism Characterization Profiling in General Purpose Computing Applications

  • Wang, Yaobin;An, Hong;Liu, Zhiqin;Li, Li;Yu, Liang;Zhen, Yilu
    • Journal of Computing Science and Engineering
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    • v.9 no.1
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    • pp.20-28
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    • 2015
  • General purpose computing applications have not yet been thoroughly explored in procedure level speculation, especially in the light-weighted profiling way. This paper proposes a light-weighted profiling mechanism to analyze speculative parallelism characterization in several classic general purpose computing applications from SPEC CPU2000 benchmark. By comparing the key performance factors in loop and procedure-level speculation, it includes new findings on the behaviors of loop and procedure-level parallelism under these applications. The experimental results are as follows. The best gzip application can only achieve a 2.4X speedup in loop level speculation, while the best mcf application can achieve almost 3.5X speedup in procedure level. It proves that our light-weighted profiling method is also effective. It is found that between the loop-level and procedure-level TLS, the latter is better on several cases, which is against the conventional perception. It is especially shown in the applications where their 'hot' procedure body is concluded as 'hot' loops.