• Asian Oncology Nursing
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• v.12 no.1
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• pp.52-60
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• 2012

Purpose: This study is to determine knowledge about early detection and risk perception of cancer according to taking cancer screening tests in the general population. Methods: The participants were 151 people aged 40 years or older. A questionnaire consisted of knowledge about early detection (warning signs, cancer screening methods, general knowledge for early detection), cancer risk perception and history of cancer screening during past 2 years. Results: The percentages of correct answers were 64.7% in knowledge about warning signs, 73.7% in knowledge of cancer screening tests and 80.1% in general knowledge for early detection. Participants had the highest knowledge about screening methods for stomach cancer and the lowest for liver and colon cancer. The level of risk perception was medium. The participants who participated in cancer screening showed lower risk perception than those who did not. There was no significant relationship between knowledge and performance of cancer screening. The primary reason for not participating in cancer screening was patient's perception of their own health. Conclusion: These results suggest that cancer risk perception can affect the performance of cancer screening and we need to study how to handle this problem. Additionally screening programs should focus on liver cancer and colon cancer.

• Journal of the Korea Safety Management & Science
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• v.17 no.4
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• pp.105-112
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• 2015

Sawmilling industry remained a high risk with the average 4.73% of industrial accidents in 2010-2012 that was eight times that of general manufacturing. Sawmilling industry had 200 industrial accidents victim in average. Manufacturing process in sawmill industry contained dangerous machinery such as conveyors, roller, saw ( band saw, circular saw) etc. It may be effective to figure out the type of industrial accidents occurred in the past and extend risk assessment which can predict hazard such as near miss when implementing exposure or potential dangers in sawmill industry. This study conducted research on the actual condition on the place of industrial accident occurrence, detailed work and contact object when injured, and injured part targeting 643 businesses which had industrial accidents in 2010-2012. As the results, RPN of general sawmill industry was the highest 'ganglip saw' with 36,157. RPN of the following order were 'moving truck' with 25,454, 'special machining operations' with 22,283. Also, probability of general sawmill industry was a lots within 1 year, while risk appeared a lots within 5 years. So, risk assessment shall be needed to emphasis on accident prevention of sawmill industry. And additional work will be needed on the risk assessment in hazard prevention work of supervisors.

• Journal of the Korean Society of Safety
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• v.28 no.6
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• pp.90-96
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• 2013

Since the last 50 years, the terminology 'risk' has been widely used in general and industrial applications, with different meanings. The different definitions of risk can lead to the different risk assessments and risk management process elements, and the misunderstandings. For the reasons, the ISO(International Standard Organization) has recently defined a new risk concept through the publication of IS0 31000:2009. Although the new concept of risk was globally accepted, it seem to be argued in its definition debate. Thus, this paper reviews the definition and meaning of the concept of risk in terms of risk origin, general and industrial applications, related domestic laws and risk management standards published to improve an understanding of risk concept.

• Environmental Analysis Health and Toxicology
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• v.14 no.4
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• pp.175-187
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• 1999

To investigate the risk perception of environmental issues, two consequtive surveys were conducted to environmental professionals using a standardized questionnaire from September to October in 1999. The number of subjects were 72 for the first survey and 68 for the second one. The questionnaire was consisted of items such as the degree of environmental pollution in Korea, risk perception of some issues on human health and ecosystem, and seriousness of the problems in the real situation in Korea. For the degree of environmental pollution in Korea, the average risk rating in the second test (7.4 point) was significantly higher than that in the first test (7.2 point). The risk perception on the general human health and ecosystem, and the seriousness in Korea situation were analyzed in the order of ′air pollution′, ′water pollution′,′soil contamination′,′waste′,′toxic chemical pollutants′,′food contamination′,′ocean contamination′, ′odor pollution′, and ′noise pollution′. Also ′toxic chemical pollutants′ problem was perceived to be the highest risk on general human health or ecosystem, and on present situation in Korea. ′Automotive vehicle exhaust′ problem was perceived to be the most severe environmental problems among specific 30 items. ′Industrial source air pollution′,′toxic air pollutants′, and ′domestic and industrial source pollutants to surface water′ were relatively severe environmental problems comparing to other problems. The pollution issues were classified into four categories by two aspects of perception; risk in general setting and seriousness in Korea situation. If the issues were highly serious in Korea and low risk perception in general setting then it is named "the Korea-specific group". Those that were all high score in two aspects, named "the Common group". Those that were all low in two aspects, named "the Nonsignificant group". And the issues were high risk perception in general setting and low seriousness in Korean situation, named "the Latent group".

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4239-4242
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• 2013

It is reported that the expression level of MLL3 in gastric cancer tissue highly correlates with tumor progression. However, whether MLL3 genetic variants are associated with the risk of gastric cancer remains unclear. In this study, we conducted a genotyping analysis for MLL3 in 314 cases of gastric cancer and 322 controls from the Chinese Han population. 4 SNPs (rs6943984, rs4725443, rs3800836, rs6464211) were selected for the present analysis. We found 2 SNPs (rs6943984, rs4725443) of MLL3 gene were significantly associated with the risk of gastric cancer : the rs6943984 with the minor allele A and rs4725443 with the minor allele C revealed strong associations with increased gastric cancer risk [P < 0.001, OR=1.97, 95% CI=1.48~2.64 and P <0.001, OR=2.23, 95% CI=1.54~3.24]. Haplotype analysis of the four SNPs showed that haplotype A-T-A-C, G-T-G-C, and G-C-A-C increased the risk of gastric cancer (P <0.001, P=0.18, and P<0.001, respectively), while haplotype G-T-A-C significantly reduced the risk of gastric cancer (P <0.001). We concluded that MLL3 variants are significantly associated with gastric cancer risk. Our results for the first time provided new insight into susceptibility factors of MLL3 gene variants in carcinogenesis of gastric cancer of the Chinese Han population.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3325-3328
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• 2012

Aim: To evaluate the association of glutathione S-transferases gene polymorphisms with the risk of gastric cancer, with reference to smoking and Helicobacter pylori infection. Methods: We conducted a 1:1 matched case-control study with 410 gastric cancer cases and 410 cancer-free controls. Polymorphisms of GSTM1, GSTT1 and GSTP1 were determined using PCR-CTPP. Results: The GSTM1 and GSTT1 null genotypes were significantly associated with the risk of gastric cancer after adjusting for potential confounding factors (OR=1.68, 95% CI=1.32-2.23 for null GSTM1, OR=1.73; 95% CI=1.24-2.13 for null GSTT1). The combination of null GSTM1 and null GSTT1 conferred an elevated risk (OR=2.54, 95% CI=1.55-3.39). However, no association was found for GSTP1 polymorphism The smoking modified the association of GSTM1 and GSTT1 null genotypes with the risk of gastric cancer. Conclusion: GSTM1 and GSTT1 null genotypes are associated with increased risk of gastric cancer, and smoking modifies the association.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3601-3604
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• 2012

Purpose: Numerous studies have evaluated the association between XRCC1 Arg399Gln gene polymorphism and hepatocellular carcinoma risk in the Chinese Han population. However, the results have been inconsistent. We therefore here examined whether the XRCC1 Arg399Gln gene polymorphism confers hepatocellular carcinoma risk by conducting a meta-analysis. Methods: PubMed, Google scholar and China National Knowledge Infrastructure databases were searched for eligible articles in English and Chinese that were published before April 2012. Results: 6 studies involving 1,246 patients with hepatocellular carcinoma and 1,953 controls were included. The association between XRCC1 Arg399Gln gene polymorphism and hepatocellular carcinoma in the Chinese Han population was significant under GG vs AA (OR = 1.48, 95% CI = 1.13 to 1.94). Limiting the analysis to the studies with controls in the Hardy-Weinberg equilibrium, the results were persistent and robust. Conclusions: In the Chinese Han population, the XRCC1 Arg399Gln gene polymorphism is associated with an increased hepatocellular carcinoma risk.

• Korean Journal of Construction Engineering and Management
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• v.6 no.5 s.27
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• pp.177-185
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• 2005

Construction uncertainties are frequently exposed to the claims. In most cases, an interpretation of the claims is based on the construction contract. Therefore, the key points of contract negotiation are how to fairly distribute the contract risks to the client and contractor. For these, a FIDIC that is considered as an international standard contract form would be a good reference to decide reasonable contract risk distribution. In order to find out any unreasonable and unfair contract clauses at the general conditions of contract applying generally to public construction project in Korea, this study surveys, analyses and evaluates the general conditions of contract based on a FIDIC, and then proposes a risk mitigation methodology to response those clauses' risk factors reasonably.

• Proceedings of the Korean Society of Toxicology Conference
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• 2005.05a
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• pp.207-207
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• 2005

• Journal of Navigation and Port Research
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• v.35 no.1
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• pp.23-30
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• 2011

This study was carried out in order to verity the usefulness of FSA(Formal Safety Assessment) methods as a tool to conduct a safety assessment of general cargo ships flying the Korean flag, and to provide useful information on 'the Safety of General Cargo Ships' for IMO committee's discussion on the matter at a future session. In the previous paper, "A Study on High-level FSA for Korean-flagged General Cargo Ships(1)", the concepts of the FSA methodology and its five steps were described and the results of Hazard Identification(Step 1) and Risk Analysis(Step 2) from the FSA study for the Korean-flagged general cargo ships were discussed. Subsequent to the Steps 1 & 2, the identification of Risk Control Options(RCOs-Step 3) for eliminating or reducing either the frequency or the severity of the risks identified and their Cost-Benefit Assessment(CBA-Step 4) were undertaken. In this paper, the results of the Steps 3 & 4 are discussed, and some recommendations are made.