• 대한한의학방제학회지
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• 제25권3호
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• pp.363-374
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• 2017

Dried fruits of Schizandra chinensis Baillon, Fructus Schisandrae, have been widely used for many years to prevent and treat various diseases in Asian countries including Korea and Russia. It has recently been reported that extracts of Fructus Schisandrae are effective for controlling muscle and skeletal diseases. In this study, we investigated the efficacy of ethanol extract of Fructus Schisandrae (EEFS) on apoptosis and inflammatory response in gastrocnemius muscle of dexamethasone-induced catabolic muscle atrophy mice as part of natural substance discovery and functional analysis for improving muscle function. According to the results of this study, EEFS supplementation attenuated body weight gains and suppressed calf thickness loss in dexamethasone-induced muscle atrophic mice. Gastrocnemius muscle immunohistochemistry showed that expression of caspase-3 and poly(ADP-ribose) polymerase, which are representative apoptotic markers, was markedly increased in dexamethasone control mice; however, their expression was effectively reduced in the EEFS-fed mice. EEFS supplementation also prevented dexamethasone-induced increases in immunoreactivity of muscle fibers for myostatin, an important negative regulator of skeletal muscle mass. In addition, EEFS significantly normalized the increased numbers of nitrotyrosine, 4-hydroxynonenal and inducible nitric oxide synthase-positive muscle fibers compared to that found in dexamethasone control mice. These results suggest that EEFS protects dexamethasone-induced muscular atrophy by decreasing apoptosis and inflammatory responses, and EEFS is more likely to be developed as a muscle strengthening agent.

• 대한물리의학회지
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• 제12권2호
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• pp.1-8
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• 2017

PURPOSE: The purpose of this study was investigate the changes of gastrocnemius (GCM) muscle activity by applying different hot and cold therapeutic modalities. METHODS: A total of 20 healthy subjects were enrolled into the study. We selected transfer modalities that are frequently used in clinical settings: conduction, radiation, and convection. We performed hot pack, ice pack, and infrared therapy for 10, 20, and 30 minutes. After each application, a break was taken between each day. In addition, we performed cryotherapy for 3 min (airflow rate = $-6{\sim}-20^{\circ}C$). We measured muscle activity changes in the GCM muscle. RESULTS: For the conduction method, muscle activity significantly increased after ice pack therapy for 10 min and 20 min but decreased after hot pack therapy for 10 min and 20 min. For the radiation method, muscle activity significantly decreased after infrared therapy for 10 min and 20 min. For the convection method, muscle activity significantly increased after cryotherapy for 3 min and 10 min. There were no differences in the change of muscle activity in the conduction and radiation transfer method using heat. However, there were differences in the change of muscle activity in the conduction and convection transfer method with cold application. CONCLUSION: For a reduction in muscle activity, regardless of the transfer type, thermal application for 20 min would be effective. For an increase in muscle activity, cold pack application or cryotherapy for 20 min would be effective. This study could contribute toward therapeutic modality application in changing muscle activity.

• 대한물리의학회지
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• 제14권3호
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• pp.127-133
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• 2019

PURPOSE: The aim of this study was to obtain detailed and quantified data concerning the effects of plantarflexor fatigue induced to the non-paretic side on muscle activities of the bilateral lower extremities during walking in chronic stroke patients. METHODS: In this study, chronic stroke patients were evaluated for six months after the onset of stroke. To induce the non-paretic plantarflexor fatigue, 20 chronic stroke patients were asked to perform their given fatigue affecting assignments, which were presented in a forced contraction fatigue test method, until the range of motion of the plantarflexor was reduced to less than 50%. The muscle activities of the rectus femoris, tibialis anterior and gastrocnemius in the paretic and non-paretic lower extremities were measured using a wireless surface EMG before and after muscle fatigue induction. RESULTS: The findings showed that after plantarflexor fatigue was induced on the non-paretic side, a significant decrease in muscle activities of the rectus femoris on the paretic side was noted (p<.05). The muscle activities of the tibialis anterior and gastrocnemius were also observed to decrease, but, these results were not statistically significant (p>.05). In the non-paretic side, there was a significantly decrease in the muscle activities of the rectus femoris, tibialis anterior, and gastrocnemius (p<.05). CONCLUSION: These finding suggest that the muscle fatigue of the non-paretic plantarflexor affects not only the muscle activity of the ipsilateral lower extremity but also the muscles activity of the contralateral lower extremity. This highlights the necessity of performing exercise or training programs that do not cause muscle fatigue in clinical aspects.

• PNF and Movement
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• 제20권3호
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• pp.443-449
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• 2022

Purpose: This study aims to identify the differences in the muscle activity of the ankle joint muscle depending on the type of footwear (sneakers, mule sneakers, slippers) worn while walking on a slope. Methods: The subjects wore each shoe (sneakers, mule sneakers, and slippers) and walked on an 18-degree slope at a speed of 110 beats/min. While walking, the muscle activities of the tibialis anterior and medial gastrocnemius were measured. Of the three walking cycles, the second walking cycle was measured except for the first and third walking cycles, which are the beginning and end, and a three-minute break was taken to prevent muscle fatigue when the type of footwear was changed. Results: When walking on a slope, there was no significant difference in the muscle activity of the tibialis anterior according to the type of footwear. However, when walking on a slope, the difference in muscle medial gastrocnemius muscle activity was significant between sneakers and mule sneakers. There was also a significant difference between sneakers and slippers, but there was no significant difference between slippers and mule sneakers. Conclusion: There was no significant statistical difference between sneakers and mule sneakers, but there was a numerical difference. Therefore, the presence or absence of the shoe collar may affect the muscle activity of the medial gastrocnemius when walking on a slope. This can lead to patellofemoral pain syndrome caused by the excessive use of the quadriceps, so it must be considered that caution is needed.

• 대한임상전기생리학회지
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• 제1권1호
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• pp.31-43
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• 2003

The present studies are designed to determine whether the NMES can affect the muscle atrophy in rats following administration of steroid. Rats were divided into four groups: 1) Control group treated with administration of distilled water. 2) The group treated with administration of steroid. 3) The group treated with NMES once a day after adminstration of steroid. 4) The group treated with NMES twice a day after administration of steroid. The muscle atrophy was induced by one week administration of dexamethasone once a day by 3 mg/kg. The change in the structure of muscle fiber and the amount. of myofibril protein and gastrocnemius were determined after every week dissection of the tissues. The results were as follows; 1. The administration of steroid significantly affected the decrease in the weight, but NMES did not affect the inhibition of decrease in the weight. 2. The weight of gastrocnemius in the group once treated with NMES was changed two weeks later; similarly in the group twice treated with NMES significantly did two or three weeks later. These indicated that NMES affected the muscular activation of gastrocnemius(p<.05). 3. The changes in the amount of gastrocnemius protein by NMES might, indicate that NMES activated the capacity of synthesis of muscle fiber protein(p<.05).

• 대한물리의학회지
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• 제9권4호
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• pp.347-354
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• 2014

PURPOSE: This study was to examine changes in muscle activity of lower extremity shoes sole form (high heels, shoes with curved out sole, house shoes). METHODS: The subjects of this study were 12 women in their twenties. They put three kinds of shoes (high heels, shoes with curved out sole, house shoes) and walked 5m. The muscles activities of lower extremity muscles (rectus femoris, vastus medialis, tibialis anterior, gastrocnemius medial part) were measured using a wireless electromyogram (EMG). Rectus femoris was attached to 1/2 position at the distance between ASIS and knee bone and vastus medials was attached to 2cm from upper inside of knee bone. Tibialis anterior was attached to 75% position above line connecting knee joint and ankle joint and gastrocnemius medial part was attached to 3 5% position above knee joint and ankle. RESULTS: It was found that there were significant differences in changes of muscles activities of lower extremity muscles (rectus femoris, vastus medialis, tibialis anterior, gastrocnemius medial part) on shoes sole forms (p<.05). All lower extremity muscles were showed high muscles activities, when high heels wear (p<.05). Wearing shoes with curved out sole was showed high muscle activity of tibialis anterior and lower muscle activity of gastrocnemius medial part compared with wearing house shoes (p<.05). CONCLUSION: Shoes sole form should be considered when patients with knee and ankle joint problems choose shoes because muscles were showed different activities according to shoes sole forms.

• 한국운동역학회지
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• 제16권3호
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• pp.117-124
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• 2006

The modern convenient life formed by industrial development becomes lack of exercise and takes an interest in diet. Specially, professional walking shoes is developed as people take an interest in jogging, Those shoes, professional walking shoes or Dietshoes, increase exercise effects by change of heel types. Therefore, this study investigated motility effects by EMG experiment in order to measure Muscle Activities (MA) while wearing diet shoes (backless). Experiment was conducted by EMG measurement, from calf (gastrocnemius muscle), thigh (vastus muscle) and waist (erector spinae muscle), of 12 high school students. Exercise effects between the two shoes were analyzed by EMG (MF; Median Frequency, MPF; Mean Power Frequency, ZCR; Zero Crossing Rate). Results showed that the Dietshoes(MF: 48.21Hz, MPF: 65.0Hz, ZCR: 100.6Hz) had larger EMG value than that of Normal shoes(MF: 40.47Hz, MPF: 58.04Hz, ZCR: 82.09Hz). Also, in MA, the highest activities are showed in the calf, the second one is in waist, and last one is in thigh during gate. ANOVA between shoes in measurement parts showed significant effects in MF (gastrocnemius: p-value=.022, vastus laterals: p-value=.037, erector spinae: p-value=.082), MPF (gastrocnemius: p-value=.032, vastus laterals: p-value=.046, erector spinae: p-value=.090), and ZCR (gastrocnemius: p-value=.000, vastus laterals: p-value=.004, erector spinae: p-value=.134). And MA of Dietshoes is higher than that of Normal shoes, and decreasing rate of MA in Dietshoes is less than that of Normal shoes. Thus, this study validates exercise effects of Dietshoes.

• 대한한의학방제학회지
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• 제24권4호
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• pp.311-321
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• 2016

Chronic or acute alcohol abuse often leads to liver injury associated with alcoholic hepatitis, liver fibrosis, cirrhosis, and liver cancer. In addition to the liver, alcohol abuse also induces a variety of other tissue injuries including pancreatitis, cardiomyopathy, neurotoxicity and muscle loss. Chronic skeletal muscle myopathy, independent of peripheral neuropathy, is well recognised in alcoholic patients. Several mechanisms may be involved in the pathogenesis of alcoholic myopathy. Ethanol is a potent inhibitor of muscle protein synthesis. Gastrocnemius and plantaris muscles are Type II fiber-predominant and usually considered representative of the musculature as a whole. Whereas, soleus muscle is Type I fiber predominant. Shihosogan-san is a traditional Korean medicine that is widely employed to treat indigestion and liver diseases. Muscle diseases are often related to liver diseases and conditions. We therefore tested the hypothesis that treatment with Shihosogan-san could ameliorate the ethanol-induced changes in muscle protein synthesis. Young male Sprague-Dawley rats were orally given 25% ethanol (5ml/kg, body weight) daily with Ethanol for 28 days. Normal group was similarly administrated with saline. In Shihosogan-san treated group, rats were orally administrated Shihosogan-san extract, and rats of EtOH group were given with the vehicle only. After 4 week, the morphology of gastrocnemius and plantaris muscles were assessed by hematoxylin and eosin staining. For comparative purposes, liver function was also investigated. The muscles from rats of EtOH group displayed a significant reduction in average cross section area compared to Normal group. Shihosogan-san treated group had increased fiber compared to the EtOH group. Moreover, Shihosogan-san treated group compared with EtOH group showed significantly decreased pro-apoptotic BAX expression and increased anti-apoptotic Bcl-2 expression. In conclusion, Shihosogan-san extract showed ameliorating effects on chronic alcohol toxicity in skeletal muscle.

• 대한인간공학회지
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• 제29권5호
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• pp.789-795
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• 2010

This study aimed to investigate the effect of differing heel height on static balance and muscle activation of ankle joint during standing. Twenty-one young females volunteered to participate in this study. To measure balance function and EMG activity of tibialis anterior and gastrocnemius muscles, the subjects were asked to perform 1-min standing with eyes open and closed state under 3 different heel heights: barefoot, 3cm, and 7cm each. During the standing, postural sway distance and area, and EMG activity of tibialis anterior and gastrocnemius muscles were significantly augmented with increasing heel height (p<0.05). For comparison between eyes open and closed in terms of postural sway area and EMG activity of tibialis anterior muscle, barefoot and 7cm height conditions respectively showed significant differences as well. The findings indicate that high-heeled shoes may have disadvantages in maintaining balance function because of extra-muscular effort of ankle joint. This study provides useful information that will inform future studies on how heel height affects muscle activity around the ankle joint in aspects of static and dynamic balance.

• Parasites, Hosts and Diseases
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• 제52권1호
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• pp.69-73
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• 2014

Sparganosis is a parasitic infection caused by the plerocercoid tapeworm larva of the genus Spirometra. Although the destination of the larva is often a tissue or muscle in the chest, abdominal wall, extremities, eyes, brain, urinary tract, spinal canal, and scrotum, intramuscular sparganosis is uncommon and therefore is difficult to distinguish from a soft tissue tumor. We report a case of intramuscular sparganosis involving the gastrocnemius muscle in an elderly patient who was diagnosed using ultrasonography and MRI and treated by surgical excision. At approximately 1 cm near the schwannoma at the right distal sciatic nerve, several spargana worms were detected and removed.