• Title/Summary/Keyword: Gamma irradiating test

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A Test of Antifungal Spray Formulation Containing Nanosized Silica-Silver Particles Prepared by Using Gamma Irradiation for Practical Use to Control Indoor Fungi (감마선 조사에 의해 제조된 나노-실리카은 유무기복합 입자를 포함한 항진균성 스프레이 제제의 생활환경 저해균에 대한 실용성 검토)

  • Kim, Seong-Ho;Park, Hae-Jin;Kim, Hwa-Jung;Park, Hae-Jun
    • Journal of Radiation Industry
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    • v.2 no.3
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    • pp.149-154
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    • 2008
  • The present study described an antimicrobial spray composition comprising nanosized silica-silver particles, in which nano-silver is bound to silica molecules and a water-soluble polymer, the nanosized silica-silver particles prepared by irradiating a solution comprising a silver salt, silicate and the water-soluble polymer with radiation rays. According to a surfactant addition, the compositions were not turbid and were colorless. Also samples (cotton fabrics and wallpaper) were treated with the compositions also did not cause any stains even after drying under sunshine and at $80^{\circ}C$. Our results suggested that the spray formulation product was of practical use to control indoor fungi.

Effect of Gamma Ray Irradiation on the Availability of Applied $^{65}Zn$ to Applied at Organic Matter Added Soils under Laboratory Conditions

  • Kim, Tai-Soon;Han, Kang-Wan
    • Nuclear Engineering and Technology
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    • v.11 no.2
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    • pp.105-110
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    • 1979
  • In order to evaluate the effect of gamma ray irradiation to the soils added with several organic matters on release sad fixation of $^{65}Zn$, a soil incubation test was carried out by use of an acidic and a calcareous soil. The results obtained were summarized as follows : DTPA extractable $^{65}Zn$ decreased gradually with elapsed time of incubation owing to fixation of $^{65}$Zn by the soils but after four weeks DTPA extractable $^{65}Zn$ was reached an equilibrium state. The most parts of $^{65}Zn$ activity in the equilibrium state was found in the solid phase. The extent of zinc fixation in acidic Keumgok and calcareous Jecheon soils represented as activity basis was 89 and 93.7 per cent of applied $^{65}Zn$ respectively. Increased tendency of DTPA extractable zinc was shown by irradiating gamma ray to both soils because of $^{65}Zn$ fixation could be decreased by irradiation. The extractability of fixed $^{65}Zn$ by DTPA solution was 38.9 per cent in acidic Keumgok soil and only 9.5 per cent in calcareous Jecheon soil. Release of fixed $^{65}Zn$ by irradiation of gamma ray is closely related to pH of both soils. Much more $^{65}Zn$ could be released under low pH condition. Effect of gamma ray irradiation to organic matter sources on release of $^{65}Zn$ could not be differentiated. But in the case of nonirradiated soils, however, glucose treated soils couldrelease much more the extractable zinc as compared to those of the straw or cellulose treatment.

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Effects of Gamma-irradiation on Anti-diabetic and Cytotoxic Activities of Heat-treated Mistletoe (Viscum album) (감마선 조사가 열처리 겨우살이의 항당뇨 및 세포독성에 미치는 영향)

  • Park, Jong-Heum;Kim, Su-Min;Sung, Nak-Yun;Song, Du-Sup;Byun, Eui-Baek;Kim, Jae-Kyung;Song, Beom-Seok;Lee, Ju-Woon;Kim, Jae-Hun
    • Journal of Radiation Industry
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    • v.7 no.2_3
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    • pp.183-190
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    • 2013
  • Mistletoe (Viscum album) has been widely used as a functional food material for various therapeutic purposes from ancient time. In this study, we examined anti-diabetic and cytotoxic activities of heated-treated mistletoe and the effects of gamma-irradiation on its activities. Heat-treated mistletoe extract was prepared by heating during different time (3, 6, 9 and 12 h) and gamma-irradiated with different doses of 0, 10, 30, 50, 70 and 100 kGy. Heat-treated mistletoe extracts showed a concentration-dependent cytotoxicity on rat insulinoma RINm5F cells and the effect was gradually decreased as heating time increased up to 12 h. 12 h heat-treated extract was no cytotoxic. Gamma-irradiation enhanced the reduction of heat-treated mistletoe-induced cytotoxicity and the decreasing effect was an irradiating dose-dependent. In particular, all of 70 kGy irradiated and heat-treated mistletoe extracts did not showed the cytotoxicity and the effect was comparable to 12 h heat-treated mistletoe extract. Among those extracts, 3 h heat-treated mistletoe extract gradually increased the insulin secreting activity by gamma-irradiation and the effect was the best at 70 kGy, whereas 12 heat-treated extract was no effect. On the test of ${\alpha}$-glucosidase inhibitory activity, 3 h heat-treated mistletoe extract showed the concentration dependent effects and gamma-irradiation induced more activity at 70 kGy, compared to non-irradiated 3 h and 12 h heated mistletoe extracts. These results suggest that the combination of heat treatment and gamma-irradiation might be more effective than only heat-treatment for improving the anti-diabetic activity of mistletoe extract and reducing its cytotoxicity.

The Alignment Evaluation for Patient Positioning System(PPS) of Gamma Knife PerfexionTM (감마나이프 퍼펙션의 자동환자이송장치에 대한 정렬됨 평가)

  • Jin, Seong Jin;Kim, Gyeong Rip;Hur, Beong Ik
    • Journal of the Korean Society of Radiology
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    • v.14 no.3
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    • pp.203-209
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    • 2020
  • The purpose of this study is to assess the mechanical stability and alignment of the patient positioning system (PPS) of Leksell Gamma Knife Perfexion(LGK PFX). The alignment of the PPS of the LGK PFX was evaluated through measurements of the deviation of the coincidence of the Radiological Focus Point(RFP) and the PPS Calibration Center Point(CCP) applying different weights on the couch(0, 50, 60, 70, 80, and 90 kg). In measurements, a service diode test tool with three diode detectors being used biannually at the time of the routine preventive maintenance was used. The test conducted with varying weights on the PPS using the service diode test tool measured the radial deviations for all three collimators 4, 8, and 16 mm and also for three different positions of the PPS. In order to evaluate the alignment of the PPS, the radial deviations of the correspondence of the radiation focus and the LGK calibration center point of multiple beams were averaged using the calibrated service diode test tool at three university hospitals in Busan and Gyeongnam. Looking at the center diode for all collimators 4, 8, and 16 mm without weight on the PPS, and examining the short and long diodes for the 4 mm collimator, the means of the validation difference, i.e., the radial deviation for the setting of 4, 8, and 16 mm collimators for the center diode were respectively measured to 0.058 ± 0.023, 0.079 ± 0.023, and 0.097 ± 0.049 mm, and when the 4 mm collimator was applied to the center diode, the short diode, and the long diode, the average of the radial deviation was respectively 0.058 ± 0.023, 0.078 ± 0.01 and 0.070 ± 0.023 mm. The average of the radial deviations when irradiating 8 and 16 mm collimators on short and long diodes without weight are measured to 0.07 ± 0.003(8 mm sd), 0.153 ± 0.002 mm(16 mm sd) and 0.031 ± 0.014(8 mm ld), 0.175 ± 0.01 mm(16 mm ld) respectively. When various weights of 50 to 90 kg are placed on the PPS, the average of radial deviation when irradiated to the center diode for 4, 8, and 16 mm is 0.061 ± 0.041 to 0.075 ± 0.015, 0.023 ± 0.004 to 0.034 ± 0.003, and 0.158 ± 0.08 to 0.17 ± 0.043 mm, respectively. In addition, in the same situation, when the short diode for 4, 8, and 16 mm was irradiated, the averages of radial deviations were 0.063 ± 0.024 to 0.07 ± 0.017, 0.037 ± 0.006 to 0.059 ± 0.001, and 0.154 ± 0.03 to 0.165 ± 0.07 mm, respectively. In addition, when irradiated on long diode for 4, 8, and 16 mm, the averages of radial deviations were measured to be 0.102 ± 0.029 to 0.124 ± 0.036, 0.035 ± 0.004 to 0.054 ± 0.02, and 0.183 ± 0.092 to 0.202 ± 0.012 mm, respectively. It was confirmed that all the verification results performed were in accordance with the manufacturer's allowable deviation criteria. It was found that weight dependence was negligible as a result of measuring the alignment according to various weights placed on the PPS that mimics the actual treatment environment. In particular, no further adjustment or recalibration of the PPS was required during the verification. It has been confirmed that the verification test of the PPS according to various weights is suitable for normal Quality Assurance of LGK PFX.