• Nuclear Engineering and Technology
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• v.54 no.8
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• pp.3176-3180
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• 2022

A gamma irradiator is a well-developed installation for gamma radiation sterilization. A "shuffle-dwell" mode is preferable for high dose applications. A novel configuration of a shuffle-dwell gamma irradiator is proposed to increase energy utilization and throughput, which would result in higher profitability. While the minimum distance between any irradiation position and each source pencil, the minimum distance between the neighboring irradiation positions and the size of source pencils are kept the same as the current configuration, the irradiation positions and source pencils are rearranged based on the fact that radiation is emitted in an isotropic fashion. The computational results suggest that the proposed configuration requires an 8.7% smaller area and exposes the product to 11.8% more gamma radiation in a 10.7% shorter irradiation time. In other words, the proposed configuration needs a smaller area and shorter irradiation time to have a better performance compared to the current shuffle-dwell gamma irradiator. Note that the claim is based primarily on an analytical calculation. Experimental and manufacturing among other practical considerations will be taken into account in the future work to exhaustively evaluate the performance of the proposed configuration and to compare it with that of the traditional configuration.

• Progress in Medical Physics
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• v.22 no.4
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• pp.198-205
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• 2011

Gamma irradiator is widely used for cell, animal experiment, irradiation for blood, dose measurement, and education. Biobeam8000 gamma irradiator (STS Steuerungstechnik &. Strahlenschutz GmbH, Braunschweig, Germany, Cs137, 81.4 TBq) that KIRAMS (Korea Institute of Radiological and Medical Science) has is a irradiation device that enables to be used in large-capacity of 7.5 L and extensive area. Cs-137 source moves range of 24 cm back-and-forth in a regular cycle in beaker for uniform irradiation and a beaker that puts a specimen like existing radiation irradiator such as Gammacell3000 rotates $360^{\circ}$ during irradiation. Precise dose information according to the location of radiation source would be needed because of the movement of radiation source, whereas radiation could be uniformly irradiated in comparison with existing gamma irradiator. In this study, dose distribution of the inside beaker located in Biomeam8000 gamma irradiator was measured using glass dosimeter, and dose evaluation and distribution regarding dose linearity and dose reproducibility were implemented based on measurement results. This aims to show guideline for efficient use of irradiator based on measurement result when doing experiment or radiation exposure.

• Progress in Medical Physics
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• v.22 no.3
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• pp.124-130
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• 2011

In this study the dosimetric evaluation for a biological sample irradiated by gamma rays from Cs-137 irradiator (Gamma Irradiator, Chiyoda Technol Co., Japan) was performed for radiobiological experiment. A spherical water with a diameter of 3 cm was assumed as a biological sample. The absorbed dose were determined by the air kerma based dosimetric calculation system. The theoretical and Monte Carlo calculations (MCNPX) were performed and compared to evaluate measured air kerma and determined absorbed dose respectively. As a result of comparison with theoretical calculation, the measured air kerma was in good agreement within 3.1% at the distance of 100 and 200 cm from the source. In comparison with Monte Carlo results the determined absorbed dose along the central axis was in good agreement within 1.9% and 3.7% at 100 cm and 200 cm respectively. Although the preliminary results were obtained in this study these results were used as a basis of dosimetric evaluation for radiobiological experiment. Extended study will be performed to evaluate the dose in various conditions of biological samples.

• Journal of Electrical Engineering and Technology
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• v.9 no.6
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• pp.2065-2069
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• 2014

The DAC-7512E is a 12-bit digital to analog converter that is low power and a single package with internal buffers. The DAC-7512E takes up minimal PCB area for applications of space power electronics design. The spacecraft mass is a crucial point considering spacecraft launch into space. Therefore, we have performed a TID test for the DAC-7512E 12-bit serial input digital to analog converter to reduce the spacecraft mass by using a low-level Gamma-ray irradiator with $Co^{60}$ gamma-ray sources. The irradiation with $Co^{60}$ gamma-rays was carried out at doses from 0 krad to 100 krad to check the error status of the device in terms of current, voltage and bit error status during conversion. The DAC-7512E 12-bit serial digital to analog converter should work properly from 0 krad to 30 krad without any error.

• Progress in Medical Physics
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• v.24 no.3
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• pp.140-144
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• 2013

In this research, the glass dosimeter was calibrated to measure the standard absorbed dose of the Cs-137 irradiator and absorbed dose in a biological sample. Absorbed dose in water for Cs-137 gamma ray was determined by the IAEA TRS-277 protocol. The PTW-TM30013 ion chamber and the PTW-TM41023 water phantom were utilized for measuring absorbed dose and the value was compared with the reading from DoseAce GD-302M glass dosimeter from Asahi Techno Glass Corporation for its calibration. The uncertainty of measurement ($1{\sigma}$) of the calibrated glass dosimeter was 2.7% and this result would be applied to improve the accuracy in measurement of absorbed dose in a biological sample.

• Nuclear Engineering and Technology
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• v.55 no.9
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• pp.3383-3387
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• 2023

A new dyed polyvinyl alcohol (PVA) film dosimeter based on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MMT) tetrazolium dye is proposed in this study for measuring high gamma radiation dose. Gamma cell irradiator that contains Co-60 gamma-ray source was used to expose the novel MMT-PVA films to different doses up to 25 kGy. The changed in optical property of irradiated and unirradiated films were characterized by UV-Vis spectrophotometer. The results show that the dose sensitive and the linear range of irradiated films were increased considerably with increase of MMT concentration from 1 to 5 mM. The dose response of dyed PVA film changed substantially with changing relative humidity (12-74%) as well as irradiation temperature (10-40 ℃). The absorbance of the unirradiated films does not change up to 10 days in dark while a significant increase in their absorbance was reported for similar films under fluorescent light. The irradiated dosimeters that kept in dark showed a perfect stability for 54 days. It was found that no obvious impact of dose rate on the irradiated MMT-PVA film dosimeters.

• Journal of the Korean Society of Radiology
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• v.12 no.2
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• pp.179-184
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• 2018

In this study, we compared the measured values of the effective beam size of standard gamma irradiator with the simulation results to provide a useful means to the effective beam area determination. Results of the simulation and measured using ion chamber was distributed in a relative error of 4.5 ~ 7.3% of the case of air kerma rate. The size of the effective beam area is when the simulation was implemented in the horizontal direction 27cm, 21.6cm vertical direction, the measured result using a film was obtained similar results with the horizontal direction 26.5cm, 21.9cm vertical direction. The relative error in the horizontal direction is 1.85% and 1.38% vertical effective beam area was also similarly distributed around the field gamma rays. As a result of the study, it was confirmed that the effectiveness of the simulation was sufficient for the gamma irradiation system. In particular, it is small relative errors in the effective beam size than the air kerma rate is considered to be due to the size of the beam is determined by geometric factors rather than the capacity of the standard source. A further study is needed to improve the reliability of the photon energy distribution diagram using simulation.

• Journal of Radiation Industry
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• v.5 no.4
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• pp.347-352
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• 2011

In order to identify the genetic relationship analysis by acute and chronic gamma irradiation, Arabidopsis (Arabidopsis thaliana L.) were irradiated with 200 Gy of gamma-rays using gamma-irradiator (3,000 Ci; Nordion, Canada) and gamma-phytotron (400 Ci; Nordion, Canada) for acute and chronic irradiation, respectively. Genetic relationship among two acute gamma-irradiated plants (A1 and A24) and three chronic gamma-irradiated plants (C1W, C2W, C3W) were analyzed using the amplified fragment length polymorphism (AFLP) technique compared with each non-irradiated plant. A total of 28 EcoRI and MseI primer combinations were used to screen 8 treatments by the ABI3130 capillary electrophoresis system. Amplified products by 28 primer sets showed 1,679 bands with an average of 51 bands per primer combination. Out of the total bands scored, 1,164 fragments were polymorphic bands, with different alleles existing among the treatments. The cluster analysis was performed using the UPGMA (Unweighted Pair Group Method using Arithmetic) in the computer program NTSYS-pc. In clustery analysis, acute gamma-irradiation showed higher genetic variation compared with chronic gamma-irradiation.

• Journal of Radiation Industry
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• v.5 no.1
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• pp.35-39
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• 2011

This study was investigated the effect of tumor cell cytotoxicity of gamma irradiated Chaga mushroom extract (CME). CME was prepared by hot water extraction at $70^{\circ}C$ for 4 hours and lyophilized. $Ten\;mg\;ml^{-1}$ of lyophilized CME powder was dissolved with deionized water and then irradiated at the doses of 10, 50, 100, and 150kGy by cobalt 60 gamma irradiator. The gamma-irradiated and non-irradiated CME were treated into the cancer cell, including human stomach cancer and human colon cancer. Cytotoxicity against the cancer cell was increased in gamma-irradiated CME and antioxidant activity was also increased in gamma-irradiated CME, as irradiation dose increased. Therefore, it was considered that gamma irradiation was effective method for improvement of the cancer cell cytotoxicity and antioxidant activity of Chaga mushroom extract.

• Journal of Radiation Industry
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• v.4 no.4
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• pp.347-352
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• 2010

In this study, we addressed a novel nanosized curdlan-silica complex, which is curdlan bound to silica, for the development of a sustain-releasing micro element fertilizer formulation. The complex was obtained as follow steps; First, Curdlan polymer, sodium silicate ($Na_2SiO_3$) and isopropyl alcohol were dissolved in DDW. Next the resultant solution was irradiated by $^{60}Co$ gamma-irradiator (150 TBq of capacity; ACEL, Canada). Then $MgSO_4$ was treated with the resultant solution. The obtained colloidal solution was dried by freeze dryer. Finally, we obtained a novel nanosized curdlan-silica formulation containing $MgSO_4$ from the colloidal solution. The morphology of the complex was characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The nanosized curdlan-silica complex has a particle size ranging from 20 to 80 nm and high stability. Our results suggested that the nano-complex can be applicable to use in various sustain-releasing formulation for pesticide delivery system (PDS).