• Journal of Acupuncture Research
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• v.17 no.1
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• pp.129-142
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• 2000

Gamdutang aqua-acupuncture solution(GAS), Gamdutang water-extracted solution(GWS) and Degamdutang aqua-acupuncture solution(DGAS) were prepared and tested for potential antitumor activities. It was used three biomarkers (quinone reductase, omithine decarboxylase, glutathione) to test chemopreventive potentials of GAS, GWS, DGAS. GAS was potent inducer of quinone reductase activity in Hepalclc7 murine hepatoma cells in culture, whereas GWS is less potent. GAS, GWS and DGAS were significantly induced quinone reductase activity in cultured rat normal liver cell, Ac2F. Glutathione levels were increased about 1.8-fold with GAS, 1.0-1.1 fold with GWS, DGAS in cultured murine hepatoma hepaiclc7 cells. In addition glutathione s-transferase levels were increased with GAS, GWS and DGAS. The effects of GAS, GWS and DGAS were tested on the growth of Acanthamoeba castellanii. Proliferation of Acanthamoeba castellanii was inhibited by GAS, GWS and DGAS at concentradons of $1{\times}$ and $5{\times}$. These results suggest that GAS has chemopreventive potential by inducing quinone reductase and quinone reductase activities, inhibition of ornithine decarboxylase activity, and increasing glutathione levels.

• Journal of Life Science
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• v.9 no.6
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• pp.684-691
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• 1999

Gamdutang aqua-acupuncture solution (GAS), Gamdutang water-extracted solution (GWS) and Dae-Gamdutang aqua-acupuncture solution (DGAS) were prepared and tested for chemopreventive potentials. GAS was potent inducer of quinone reductase (QR) activity in Heapa1c1c7 murine hepatoma cells in culture, whereas GWS is less potent. GAS, GWS and DGAS were significantly induced QR activity in cultured rat normal liver cell, Ac2F. Glutathione (GSH) levels were increased about 1.8, 1.0 and 1.1 fold with GAS, GWS and DGAS in Hepa1c1c7 cells, respectively. In addition glutathione S-transferase (GST) activity was increased with GAS, GWS and DGAS. The effects of GAS, GWS and DGAS on the growth of Acanthamoeba castellanii were tested. Proliferation of A. castellanii was inhibited by GAS, GWS and DGAS at concentrations of 1 $\times$ and 5$\times$. These results suggest that GAS has chemopreventive potential by inducing QR and GST activities, increasing GSH levels and inhibition of polyamine metabolism.

• Nuclear Engineering and Technology
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• v.56 no.2
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• pp.715-727
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• 2024

During fast neutron imaging, besides the dark current noise and readout noise of the CCD camera, the main noise in fast neutron imaging comes from high-energy gamma rays generated by neutron nuclear reactions in and around the experimental setup. These high-energy gamma rays result in the presence of high-density gamma white spots (GWS) in the fast neutron image. Due to the microscopic quantum characteristics of the neutron beam itself and environmental scattering effects, fast neutron images typically exhibit a mixture of Gaussian noise. Existing denoising methods in neutron images are difficult to handle when dealing with a mixture of GWS and Gaussian noise. Herein we put forward a deep learning approach based on the Swin Transformer UNet (SUNet) model to remove high-density GWS-Gaussian mixture noise from fast neutron images. The improved denoising model utilizes a customized loss function for training, which combines perceptual loss and mean squared error loss to avoid grid-like artifacts caused by using a single perceptual loss. To address the high cost of acquiring real fast neutron images, this study introduces Monte Carlo method to simulate noise data with GWS characteristics by computing the interaction between gamma rays and sensors based on the principle of GWS generation. Ultimately, the experimental scenarios involving simulated neutron noise images and real fast neutron images demonstrate that the proposed method not only improves the quality and signal-to-noise ratio of fast neutron images but also preserves the details of the original images during denoising.

• Journal of Life Science
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• v.9 no.6
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• pp.677-683
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• 1999

Gamdutang aqua-acupuncture solution (GAS), Gamdutang water-extracted solution (GWS) and Dae-Gamdutang aqua-acupuncture solution (DGAS) were prepared and tested for antitumor activities. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of 5 $\times$ and 10$\times$ of GAS resulted in more than 70% inhibition of growth in Ehrlich ascites tumor cells (EATC), Hepa1c1c7 and A549. GAS at concentrations of 5$\times$ and 10$\times$ revealed more than 60% inhibition in HeLa. GWS showed more than 50% inhibition of growth with EATC and HeLa at concentrations of 5$\times$ and 10$\times$, respectively. Toxicity assay with GWS in Hepa1c1c7 and A549 revealed that more than 80% inhibition of growth at the concentration of 5$\times$ and 10$\times$. In morphological study, the number of cells were decreased, and the shape of cells was round-form in EATC, Hepa1c1c7, A549, HeLa with GAS.

• Journal of IKEEE
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• v.3 no.1 s.4
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• pp.57-68
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• 1999

DCS require a remote supervisory control that applies a various applications with a period of integrated EIC(electric instrument control) using distributed computer network. Until now, DCS has leaved something to be desired in guaranteeing real-time required in remote site plant. In this paper, each controller is designed by implementing the controller suiting with an wide area to enhance the hardware of existing PRS controller and GWS, RPS and SRS, for the efficiency of TM/TC system, Therefore, real-time emphasizes on the communication processing time, rate of system load analyzed and validity was evaluated for a each implemented controllers.

• Korean Journal of Occupational Health Nursing
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• v.33 no.3
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• pp.129-139
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• 2024

Purpose: This study aimed to examine the differences in nurses' psychosocial work environment (PWE) in integrated nursing care wards (IWs) with higher nurse staffing and general wards (GWs) with lower staffing, and to analyze the effect of PWE on their health outcomes. Methods: Data were collected from 151 nurses in IWs and 156 nurses in GWs at a tertiary hospital in Seoul in 2023. The Korean version of the Copenhagen Psychosocial Questionnaire III was used to measure PWE and health outcomes. Regression analyses were conducted to examine the effect of PWE on health outcomes. Results: The most negative aspects of the nurses' work environment were found in the work demand domain. IW nurses (vs. GW nurses) reported lower work demand, better work organization and job contents, and a more positive work-individual interface. Nurse health outcomes were also better in the IWs. Lower work demand and better work-individual interfaces were positively associated with improved health outcomes, while ward type (IW vs. GW) was not significantly related to health outcomes. Conclusion: Reducing work demand by expanding integrated nursing care services nationwide and improving nurse staffing in GWs is crucial for improving health outcomes.

• Journal of Power System Engineering
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• v.13 no.2
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• pp.63-70
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• 2009

This paper discusses the influence on long-tenn predictions of the ship response in ocean by using the Global Wave Statistics data, GWS, and wave information from the remote sensing satellites. GWS's standard scatter diagrams of significant wave height and zero-crossing wave period are suggested to be corrected to a round number of 0.01/1000 fitted with a statistical analytic model of the conditional lognormal distribution for zero-crossing wave period. The GEOSAT satellite data are utilized which presented by I. R. Young and G. J. Holland (1996, named as GEOSAT data). At first, qualities of this data are investigated, and statistical characteristic trends are studied by means of applying known probability distribution functions. The wave height data of GEOSAT are compared to the data observed onboard merchant ships, the data observed by measure instrument installed on the ocean-going container ship and so on. To execute a long-tenn prediction of ship response, joint probability functions between wave height and wave period are introduced, therefore long-term statistical predictions are executed by using the functions.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.31.3-31.3
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• 2016

Exploring a universe with gravitational waves (GWs) was only theoretical expectation for long time. In September 2015, the Laser Interferometer GW Observatory (LIGO) first detected GWs emitted from the collision of two stellar-mass black holes in cosmological distance (1.3 billion light years) on Earth. This confirms the existence of black-hole binary mergers, and further, opens a new field of GW astronomy. We begin our discussion with a list of important GW sources that can be detectable on Earth by large-scale laser interferometers such as LIGO. Focusing on compact objects such as neutron stars and black holes, we then discuss possible research in the context of GW astronomy. By coordinating with existing observatories, searching for electromagnetic waves or particles from astronomical objects, around the world, multi-messenger astronomy for the universe's most cataclysmic phenomena (e.g. gamma-ray bursts) will be available in the near future.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.78.1-78.1
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• 2014

Pulsar binaries in tight orbits are considered to emit strong gravitational waves (GWs) during the last stage of their coalescences. They form a subset of compact binary mergers, which consists of white dwarfs (WDs), neutron stars (NSs), or black holes (BHs). One of the most famous example of 'merging' pulsar binaries is the Hulse-Taylor pulsar (PSR B1913+16) discovered in 1974 by Russell Hulse and Joseph Taylor. About ten NS-NS and several tens of NS-WD binaries are known in our Galaxy. Merging binaries are rare and only a few NS-NS and NS-WD have been discovered to date. A pulsar with a black hole companion is also theoretically expected, but there is yet no detection. Within several years, direct detections of GWs from compact binary mergers will be made by laser interferometers. This will pave a way to study physics of compact binaries that cannot be reached by electromagnetic waves (EM). Pulsar binaries are of particular interest as we can use both EM and GW to probe these systems. In this talk, we present a brief overview on the Galactic pulsar populations and discuss their implications for GW detection.

• Korean Journal of Applied Biomechanics
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• v.16 no.2
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• pp.193-205
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• 2006

This study was to analysis the kinematic and kinetic differences between new walking shoe(NWS : RYN) and general walking shoe(GWS). The subjects for this study were 10 male adults who had the walking pattern of rearfoot shrike with normal foot. The movement of one lower leg was measured using plantar pressure and Vicon Motion Analysis Program(6 MX13 and 2 MX40 cameras : 100 f / s) while the subjects walked at the velocity(1.5m/s. on 2m).. The results of this study was as follows : 1. The NWS was better than the GWS that caused injuries such as adduction, abduction and pronation are reduced While walking on a perpendicular surface, the landing angle and the knees angles were extensive which makes walking more safe which reduces anxiety and uneasiness. 2. The bottom of the NWS were now made into a more circular arch which supports the weight of the body and reduces the irregular angles when wearing GWS. This arch made the supporting area more wide which made the upholding the trunk of the body more effective. The whole bottom of the foot that supports the weight is more flexible in addition, increases the safeness of walking patterns and the momentum of the body. 3. The moment the heel of the foot of the NWS touch the ground, the range of the pressure were partially notable and the range of the pressure on the upper part of the thigh were dispersed The injuries that occurred while walking. primary factors when a shock related injuries are reduced Judgements of the impacts of the knees and the spinal column dispersing could be made.