• Fisheries and Aquatic Sciences
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• v.20 no.6
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• pp.10.1-10.7
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• 2017

Small GTPases are well known as one of the signal transduction factors of immune systems. The ADP-ribosylation factors (ARFs) can be classified into three groups based on the peptide sequence, protein molecular weight, gene structure, and phylogenetic analysis. ARF1 recruits coat proteins to the Golgi membranes when it is bound to GTP. The class I duplicated ARF gene was cloned and characterized from the olive flounder (Paralichthys olivaceus) for this study. PoARF1b contains the GTP-binding motif and the switch 1 and 2 regions. PoARF1b and PoARF1b mutants were transfected into a Hirame natural embryo cell to determine the distribution of its GDP/GTP-bound state; consequently, it was confirmed that PoARF1b associates with the Golgi body when it is in a GTP-binding form. The results of the qPCR-described PoARF1b were expressed for all of the P. olivaceus tissues. The authors plan to study the gene expression patterns of PoARF1b in terms of immunity challenges.

• Journal of The Korean Society of Agricultural Engineers
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• v.51 no.3
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• pp.15-24
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• 2009

This study tried to develop a tentative evaluation system on greentourism potentials(GTP) of rural villages. The GTP evaluation system consisted of 45 detail criteria within three kinds of large scale criteria, which are human resources of residents capability, amenity resources of tourists attraction, and income resources through exchange activity between rural and urban areas. The evaluation criteria were adapted from several decades existing studies considering the hardware(facility and amenity resources) and software(human resources and programs on tourism)resources in rural villages. Two kinds of test study areas, which are subdivisions of county in a typical rural area(Boori) and an suburbanized area surrounding a big city(Chooboo), located on Keumsan county in Chungnam province, were selected to test the GTP evaluation system. The results showed that the average GTP values of each village in Boori are higher than those of Chooboo, due to higher values in criteria on amenity resources and income resources, which the typical rural area may have higher value in such criteria.

• Korean Journal of Acupuncture
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• v.23 no.2
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• pp.167-176
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• 2006

목 적 : 본 연구는 태충(太衝) 및 양지혈(陽池穴) 에 대한 전침(電鍼)이 galactosamine 을 이용한 백서의 간독성(肝毒性)을 실험적으로 유발시킨 모델에서 예방효과(豫防效果)를 알아보고자 혈청중의 $\gamma\;-GTP$, GOT, GPT, LDH, total bilirubin, total cholesterol, triglyceride 의 변화를 관찰하였다. 방 법 : 간독성은 각 군들은 간독성을 유발하지 않고 무처치한 정상군, 간독성을 유발하고 난 후 무처치한 대조군, 각각 10 Hz, 50 Hz, 100 Hz 전침을 20 일간 10 회 시행한 후 간독성을 유발한 Pre 10, Pre 50, Pre 100군 등으로 분류하였다. 결 과 : 태충(太衝) 양지혈(陽池穴)에 대한 전침(電鍼) 치료(治療)의 예방효과(豫防效果)에서는 Pre 10 군에서는 ${\gamma}\;-GTP$, GOT, GPT, total cholesterol, triglyceride이 Pre 50군에서는 ${\gamma}\;-GTP$GOT, GPT, LDH, total bilirubin, total cholesterol이, Pre 100 군에서는 ${\gamma}\;-GTP$, GOT, LDH, total bilirubin, total cholesterol이 대조군에 비해 감소하였다. 결 론 : 위의 결과를 종합해보면 간독성에 대하여 태충(太衝) 양지혈(陽池穴)의 전침(電鍼)을 시행한 모든 군에서 간능과 지절대사에서 간손상에 대한 유의한 예방효과를 나타내었다.

• The Journal of the Society of Stroke on Korean Medicine
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• v.10 no.1
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• pp.27-32
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• 2009

Object : The purpose of this study was to evaluate whether herbal medication may injure the liver function and kidney function in stroke patients. Method : We observed the serum AST, ALT, r-GTP, Creatinine, BUN of 78 patient from May 1. 2008 to June 30. 2009 admitted in Oriental Hospital of Daejeon University. Liver function and Kidney function tests were done on admission and before discharge. And all patients take herbal medicine with Western medicine. Result : AST, ALT, r-GTP, Creatinine, BUN decreased on discharge compared with the value on admission. The liver function and kidney function test score(AST, ALT, r-GTP, Creatinine, BUN) by administration period of herbal medication was not significantly changed. Conclusion : This study suggests that general herbal medication does not injure liver function and kidney function of human.

• Journal of Acupuncture Research
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• v.26 no.5
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• pp.85-94
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• 2009

Objectives : This study was designed to investigate the effect of pharmacopuncture of Mori Cortex on galactosamine-induced liver injury in rats. Methods : Male Sprague-Dawley rats were divided into 5 groups; Normal, liver injury not induced and not treated group. Control, the liver injury-induced and not treated group. Saline group, the liver injury-induced and saline injection at $BL_{18}$. HA-1 and HA-2 group, the liver injury-induced and pharmacopuncture of Mori Cortex applied to $BL_{18}$, each $1.3{\mu}g/g$, $2.6{\mu}g/g$. Then we observed the changes of ${\gamma}$-GTP, GOT, GPT, LDH, total cholesterol, triglyceride, total bilirubin. Results : Pharmacopuncture of Mori Cortex treatment significantly inhibited the activities of ${\gamma}$-GTP, GOT, total cholesterol, triglyceride and total bilirubin in HA-1 group. ${\gamma}$-GTP, GTP, LDH, ${\gamma}$-GTP levels were significantly inhibited in HA-2 group. Conclusions : These results demonstrate that the reduce of hepatic enzyme activation and lipid accumulation by pharmacopuncture of Mori Cortex may be by an antioxidant properties of Mori Cortex.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.2
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• pp.344-349
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• 2001

The removal of chlorine from aqueous solutions on dried Chlorella vulgaris(DCV) and green tea powder(GTP) were investigated as a function of contact time, pH and initial chlorine concentration. Removal by DCV and GTP reached equilibrium after 3hrs and 0.5hr, respectively. Optimum removal pH values of DCV and GTP were determined as above 10. Both Langmuir and Freundlich adsorption models were suitable for describing the short-term removal of chlorine by DCV and GTP. According to Langmuir adsorption isotherms the maximum removal capacity of DCV (2.75mg $Cl_2/mg$) was nearly two times greater than those of GTP (1.53mg $Cl_2/mg$) and activated carbon (1.47mg $Cl_2/mg$). These results suggested that Chlorella vulgaris biomass might potentially be used as an alternative to traditional water treatment materials for removal of residual chlorine in drinking water or process waste-water.

• Journal of Nutrition and Health
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• v.24 no.1
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• pp.58-65
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• 1991

The effect of habitual alcohol consumption on the nutrient intake. body weight and serum values were studied in 194 upper middle class men aged 35-55yr. living in Seoul. Each subject was interviewed to get information of alcohol and nutrients intake. Blood samples were taken. Mean values for each variable were compared by fertile of alcohol intake. The average alcohol consumption of the subject was 32.2g/day. Most of times foods were taken along with drinks. The subjects preferred food items such as meat. fish, nuts. dry fishes when they drink. High alcohol consumers had a significantly higher intake of calorie. protein, fat. Fe, and riboflavin compared to nondrinkers and moderate drinkers. Body weight was significantly higher in high alcohol drinkers followed by moderate and nondrinker groups. They also showed the higher serum values of triglyceride and r-GTP. High alcohol consumption resulted in an increased intakes of most nutrients especially calorie and fat which leads to higher body weight and higher serum concentrations of triglyceride and r-GTP. Therefore it seems that heavy alcohol drinkers are more prone to obesity and related chronic diseases.

• Journal of Photoscience
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• v.7 no.1
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• pp.31-34
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• 2000

The heterotrichous ciliate Stentor coeruieus shows a step-up photophobic response to visible light In the previous paper, the existence of GTP-binding proteins was confirmed by using the antisera against the carboxy terminal decapeptide of transducin $\alpha$ subunit. The photoreceptor, stentorin, is localized in the pigment granule. If the immunoreactive G-protein directly interacts with the photoreceptor stentorin, the G-protein expected to be located in the pigment granule rather than plasma membrane. To elucidate the function of the immunoreactive G-protein, the localization of the G-protein in Stentor coeruleus was studied. The results suggest that this G-protein is located in the myoneme involved in the contraction and extension of the cell rather than in the pigment granule.

• Proceedings of the Korea Information Processing Society Conference
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• 2004.11a
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• pp.681-684
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• 2004

본 논문에서는 기존의, 3C-3D 구조의 반도체 Spinner 장비가 동시에 처리할 수 있는 웨이퍼의 양이 3개고 제한적이며 HP와 CP Unit이 따로 존재하기 때문에 웨이퍼의 생산성을 저하시키는 단점을 보완하기 위하여 6C-6D 형태의 구조를 갖고 HP와 CP의 Unit을 HCP와 PEB Unit으로 변경시킨 새로운 구조의 Spinner를 설계하였으며, 이 장비의 로봇들을 학습시키고 테스트하기 위한 GTP 개발에 관하여 논한다. 새로운 구조의 Spinner 장비에서 각 Unit 로봇들을 효과적으로 학습시키기 위하여 장비의 구성 요소에 따라 사용자 인터페이스용 레이아웃을 능동적으로 설계하도록 하였으며 구성 요소들 간의 관계를 정의하고 사용자 편의성에 적합한 구성 요소들을 유연성 있게 배치하도록 하였다.

• Microbiology and Biotechnology Letters
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• v.23 no.3
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• pp.316-321
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• 1995

Some properties of $\beta$-1, 3-glucan synthase system in Saccharamyces cerevisiae were investigated. By extraction with detergent and salt, the membrane preparations could be dissociated into two components, one soluble, the other still membrane bound. Both components, in addition to GTP, were necessary for the activity of $\beta$-1, 3-glucan synthase like other fungi. The protective effect of guanosine nucleotides on the soluble factor pointed to the possibility that this fraction contained a GTP-binding protein. Addition of increasing amounts of soluble factor to a constant amount of insoluble catalytic factor, vice versa, gave rise to a saturation curve. These results, including different types of evidence, indicate that the soluble factor and the catalytic factor form a complex.