• The Journal of Pediatrics of Korean Medicine
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• v.31 no.1
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• pp.43-51
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• 2017

Objectives Hataedock method is a Korean medical therapy which removes fetal toxin by orally administering herbal decoction to neonates. This study was to observe skin damage and anti-inflammatory effect via regulating IL-4 activity in NC/Nga mice which were induced atopic dermatitis (AD)-like skin lesion by Dermatophagoides (D.) farinae after applying Douchi Hataedock method. Methods NC/Nga mice with 3 weeks of gestational age were used. Each 10 mice were allocated to the control group (Ctrl), the AD-induced group (AE), and the group which induced AD after administering Douchi extract (GT). After 4 weeks from administering Douchi extract to the mice, the primary AD was induced by applying D. farinae extract 6 times per week for 3 weeks and then the secondary AD was induced by the same method after 1 week from the primary AD induction. To identify the skin damage and anti-inflammatory effect, we observed LxR, IL-4, Fc ${\varepsilon}$ receptor, substance P, and $NF-{\kappa}B$. Results The GT group showed alleviation of skin injury and decrease in capillary angiogenesis. Stratum corneum damage, epithelial cell hyperplasia, lymphocyte infiltration, and capillary distribution relatively decreased in the GT group. LxR-positive reaction in the GT group were increased by 53% than that of the AE group. IL-4 production, $Fc{\varepsilon}$ receptor activity, and substance P-positive reaction in the GT group were decreased by 82%, 42%, and 82% respectively compare to those of the AE group. $NF-{\kappa}B$-positive reaction in the GT group were decreased by 15% compare to that of the AE group. Conclusions Hataedock method with Douchi extract alleviated AD via reducing inflammatory cytokines secreted at the early stage of AD. Thus, Douchi Hataedock method has a beneficial effect for the prevention and treatment of AD.

• Annals of Clinical Neurophysiology
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• v.15 no.1
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• pp.27-29
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• 2013

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.259-262
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• 2003

Group technology(GT) is a manufacturing philosophy which identifies and exploits the similarity of parts and processes in design and manufacturing. A specific application of GT is cellular manufacturing. the first step in the preliminary stage of cellular manufacturing system design is cell formation, generally known as a machine-part cell formation(MPCF). This paper presents and tests a grouping gentic algorithm(GGA) for solving the MPCF problem and uses the measurements of e(ficacy. GGA's replacement heuristic used similarity coefficients is presented.

• Korean Journal Plant Pathology
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• v.12 no.3
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• pp.351-357
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• 1996

콩으로부터 분리한 140균주의 근류균은 25균주(17.9%)가 Rhizobium fredii로 115 균주(82.1%)가 Brady-rhizobium japonicum으로 동정되었다. R. fredii에 속하는 분리 균주의 생존 pH 범위는 4..5∼9.0이었고 B. japonicum의 생육 pH 범위는 5.5∼8.0로 비교적 좁게 나타났다. B. japonicum에 속하는 98균주 중에서는 53균주(54%)가 IAA를 생산하지 않는 GT I group으로, 45균주(46%)는 IAA를 생산하는 GT II group으로 명확하게 구분되었으며, 항생물질에 대한 내성 유무에 의해 10개의 group으로 구분되었다.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1995.10a
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• pp.9-16
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• 1995

This study presents the applicable possibility of numerical optimization and Genetic Algorithm in the design of truss structures using discrete variables and real constraints. The introduction of Genetic Algorithm in the design of truss structures enables us to do easier formulation and handle discrete variables. To investigate these applicable possibility, the design of 15 - bar truss structures has been studied using GT/STRUDL and Genetic Algorithm and the results of Genetic Algorithm are compared with GT/STRUDL's.

• Proceedings of the Korean Information Science Society Conference
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• 2005.07a
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• pp.19-21
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• 2005

분산되어 있는 고성능 컴퓨팅 자원과 대규모 데이터를 효과적으로 활용하기 위해서 최근에 그리드 환경에 대한 연구가 매우 활성화되었다. 그리드 자원을 활용하여 문제를 효율적으로 실행 및 관리하고 워크플로우 문제 모델을 지원하는 범용적인 문제풀이 환경은 더욱 중요해졌다. 고성능 GT2 기반에서 개발되었던 모니터링 정보가 제공되는 워크플로우 문제풀이 환경인 CEGA를 웹서비스 기반 그리드 미들웨어인 GT4 기반에서 포팅하고 웹서비스 기반 사용 편이한 문제 설계 및 실행환경 프로토타입을 구현한다.

• Journal of Korean Society for Quality Management
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• v.12 no.1
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• pp.17-30
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• 1984

A computer method is developed for group technology layout and its simulation analysis. The method is composed of three phases: Phase I sorts the parts by its similar production routes and forms part families. Phase II plots the layout by machine cell and evaluates the group layout alternatives by the total process time analysis and the part travel distance evaluation analysis. Phase III also evaluates the alternatives by simulation analysis using SIMAN simulation software. All the computer programs are developed with BASIC except SIMAN simulation.

• JOURNAL OF ELECTRICAL WORLD
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• s.423
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• pp.98-103
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• 2012

• 열병합발전
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• s.78
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• pp.17-22
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• 2010

• Journal of applied mathematics & informatics
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• v.31 no.1_2
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• pp.199-209
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• 2013

In this paper, we study the oscillation problem of the following higher-order neutral differential equation with positive and negative coefficients and mixed arguments $$z^{(n)}(t)+q_1(t)|x(t-{\sigma}_1)|^{\alpha-1}x(t-{\sigma}_1)+q_2(t)|x(t-{\sigma}_2)|^{\beta-1}x(t-{\sigma}_2)=e(t)$$, where $t{\geq}t_0$, $z(t)=x(t)-p(t)x(t-{\tau})$ with $p(t)$ > 0, ${\beta}>1>{\alpha}>0$, ${\tau}$, ${\sigma}_1$ and ${\sigma}_2$ are real numbers. Without imposing any restriction on ${\tau}$, we establish several oscillation criteria for the above equation in two cases: (i) $q_1(t){\leq}0$, $q_2(t)>0$, ${\sigma}_1{\geq}0$ and ${\sigma}_2{\leq}{\tau}$; (ii) $q_1(t){\geq}0$, $q_2(t)<0$, ${\sigma}_1{\geq}{\tau}$ and ${\sigma}_2{\leq}0$. As an interesting application, our results can also be applied to the following higher-order differential equation with positive and negative coefficients and mixed arguments $$x^{(n)}(t)+q_1(t)|x(t-{\sigma}_1)|^{\alpha-1}x(t-{\sigma}_1)+q_2(t)|x(t-{\sigma}_2)|^{\beta-1}x(t-{\sigma}_2)=e(t)$$. Two numerical examples are also given to illustrate the main results.