• Proceedings of the Korean Aquaculture Society Conference
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• 2003.10a
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• pp.37-37
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• 2003

Intraspecific hybrids have been proven to be a useful tool for increase growth rate in some freshwater fish species. However the effects of intraspecific hybrids in seawater fish species is little known. To assess whether intraspecific hybrids in red sea bream was associated with growth enhancement, growth performances of offspring from two inbred lines, selected Korean line (KORDI-F4) and cultured Japanese line (IPN) and two intraspecific hybrids lines (KORDI-F4♀×JPN♂ and JPN♀×KORDI-F4♂) of red sea bream were compared. There's no significant difference in body weight between offspring groups during seed production period (until 4 months old). At seven months old (after three months rearing trials on sea cages communally), the offspring from KORDI-F4 (41.0±11.1g) and JPN♀×KORDI-F4♂ (39.3±8.1g) showed significantly better performance in body weight than that of the offspring from KORDI-F4♀×JPN♂ (37.0±8.1g) and IPN (35.7±9.7g). At 15 months old, the offspring from JPN♀×KORDI-F4♂ showed best growth performances in body weight, weight gain, specific growth rate among four offspring groups. As the results, the intraspecific hybrids between cultured Japanese line and selected Korean line showed superior growth performances than their paternal and maternal inbred lines.

• Journal of Ginseng Research
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• v.14 no.2
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• pp.253-264
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• 1990

The growth responses of a variety of human intestinal bacteria to extracts of Panax ginseng and five other oriental medicinal Araliaceae were elraluattd in vitro and in vivo. The extracts enhanced the growth of Brifidobnnerilrm breve and B. longlim in media with or without carbon sources, suggesting that bifidus factors) might be involved in the phenomenon. This effect was most pronounced with water extract of P. ginseng, the growth of 27 bifidobacteria strains belonging to B adolescentis, B. longum, B. brim and B. infantis being greatly stimurated, whereas seven B. bifidum strains and other bacteria such as clostridia and Escherichin soli had little or no ability to utilise it for growth. Methanol extracts of p. ginseng were found to selectively inhibit growth of various clostridia including bifidobacteria. Paraputrificum, but this effect was not observed on other bacteria including bifidobacteria. The effect of ginseng extract intake (600 mg/day for two weeks) on the faecal microflora, pH, volatile fatty acids, ammonia, putrefactive products, and -glucuronidase, -glucosidase and nitroreductase activities, and on the blood components (triglyceride, total cholesterol and ammonia) were investigated using seven healthy human volunteers. The total concentration of faecal microflora including Bifidnkaderiifm app. during the period of ginseng extract intake %twas significantly unaffected from the preceding and subsequent control peroids. However, the frequency of occurrence of subjects having C. perfringens was significantly decreased. The faecal pH value was also significantly decreased, suggesting that the intake might increase the activity of Bifidobncterium spry. Other biochemical properties in faeces did not changed significantly. The levels of ammonia and triglycerid in blood were decreased with ginseng extract intake. These results may be an indication of at least one of the Pharmacological actions of p. ginseng as an adaptogen.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.355-355
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• 2017

South Korea is largely dependent on imports of forage crops. In order to raise the self-sufficiency rate of forage crops, it is necessary to cultivate forage crops in 135,100 ha reclaimed land of South Korea. This study was conducted to investigate the growth of halophytes and forage crops in order to search for stable plants on reclaimed land. The plants were cultured in Hoagland solution and grown at 0%, 0.5%, 1.0% and 2.0% of salt concentrations. Plants with good growth at 0.5% of salt concentration were halophytes such as Suaeda asparagoides and Salsola komarovii. Salicornia herbacea and Suaeda maritima showed good growth at 2.0% salinity, and Suaeda maritima showed stable growth at all of salt concentrations. In conclusion, Suaeda asparagoides showed the best growth at 0.5% of salt concentration and was considered the most biomass at reclaimed land in Korea with less than 0.5% of salt concentration.

• Korean Journal of Veterinary Research
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• v.56 no.2
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• pp.97-101
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• 2016

Emodin is an anthraquinone derivative from the roots of Rheum officinale Baill that possesses a variety of biological activities, including inhibition of $5{\alpha}$-reductase and prostaglandin D2. In this study, we investigated whether emodin promotes hair growth. After emodin was topically applied to the shaved dorsal skin of telogenic C57BL/6 N mice, the hair growth rate and morphological analysis were evaluated in dorsal skin for 15 days. After 13 days of treatment, minoxidil or emodin (0.01% or 0.1%)-treated groups showed remarkable regrowth of hairs relative to the vehicle control group. Scoring of the hair growth and rate of hair growth area for 15 days revealed that groups treated with minoxidil and 0.1% emodin were significantly higher than the vehicle control group. Histological examination revealed the emodin and minoxidil groups markedly recovered the number and morphology of hair follicles, including the subcutis depth, relative to the vehicle group. These results suggest that emodin has an excellent promoting effect in hair growth similar to that of minoxidil and might be useful for treatment of baldness or alopecia.

• Journal of Plant Biotechnology
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• v.48 no.2
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• pp.115-122
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• 2021

Aspilia africana (Pers) C.D.Adams, a plant used for centuries in many African countries to treat diseases such as osteoporosis, malaria, tuberculosis, and diabetes, is of great pharmaceutical interest, yet there is limited scientific literature on its germination and growth. This research paper describes the effects of different commercial soils on the germination, growth, and chlorophyll content of A. africana. The germination parameters assessed included final germination percentage (FGP), mean germination time (MGT), and germination index (GI). Shoot length, leaf number, and fresh and dry weights were some of the parameters used to assess A. africana growth. The FGP was low and did not vary significantly; the MGT was 7 ~ 10 days; and the GI was significantly higher in PPS soil at 4.61 ± 0.332 days. Aspilia africana plants in HS:PPS soil showed the best overall growth, producing the highest mean leaf number (18.00 ± 1.129), longest mean shoot length (202.43 ± 13.451 mm), and highest mean fresh and dry weights (7.08 ± 1.061 g and 0.629 ± 0.112 g, respectively). The highest chlorophyll content in leaves of A. africana under HS:PPS conditions suggested a higher photosynthetic potential of plants in this soil. The best growth performance of A. africana in the HS:PPS soil could be attributed to a higher amount of certain mineral nutrients such as nitrogen, potassium, and phosphorus in the HS:PPS soil compared to the other soil categories. It is unclear why the FGP of A. africana was low and we recommend an exclusive study to investigate this further.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5315-5320
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• 2016

Purpose: Tumor cell growth and sensitivity to chemotherapy depend on many factors, among which insulin-like growth factors (IGFs) may play important roles. The aim of the present study was to evaluate the levels of insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) in primary tumors and ascites as predictors of response to neoadjuvant chemotherapy in ovarian cancer (OC) patients. Materials and Methods: Tumor tissue samples and ascitic fluid were obtained from 59 patients with advanced OC. The levels of IGF-I, IGF-II, IGFBP-3, IGFBP-4 and PAPP-A were determined using ELISA kits. Taking into account the data on expression of these IGF-related proteins and outcome, logistic regression was performed to identify predictors of response to neoajuvant chemotherapy. Results: Human ovarian tumors expressed IGFs, IGFBP-3, IGFBP-4 and PAPP-A and these proteins were also present in ascites fluid and associated with its volume. IGFs and IGFBPs in ascites and soluble PAPP-A might play a key role in ovarian cancer progression. However, levels of proteins of the IGF system in tumors were not significant predictors of objective clinical response (oCR). Univariate analysis showed that the level of IGF-I in ascites was the only independent predictor for oCR. Conclusion: The level of IGF-I in ascites was shown to be an independent predictor of objective clinical response to chemotherapy for OC patients treated with neoadjuvant chemotherapy and debulking surgery.

• Archives of Plastic Surgery
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• v.32 no.2
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• pp.149-154
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• 2005

Low-power laser(LPL) delivers a small amount of energy without elevation of tissue temperature. LPL has been reported to have biostimulation effects including anti-inflammatory, analgesic, regenerative, immunocorrective, and vasodilative effects. However, the effect of LPL on hair growth has rarely been studied. We investigated the effect of LPL on hair growth in the mouse. After depilation of back skin of mice, we classified the mice into 4 groups: control, laser irradiated group, $MoandMore^{(R)}$ applied group, and Spella $707^{(R)}$ applied group. Laser irradiation or application of these drugs were performed on the back skin of the mice for 30 days. The results are summarized as follows. Hair growth of control was first observed at 13 days after depilation, and complete hair regrowth was observed at 25 days. Hair growth of both laser irradiation group and $MoandMore^{(R)}$ applied group was first observed at 9 days after depilation, and complete hair regrowth was observed at 20 days. Hair growth of Spella $707^{(R)}$ applied group was firstly observed at the 9 days after depilation, and complete hair regrowth was observed at the 15 days. Hair growth started at the irradiation site in the laser irradiation group, but it started at the random sites in other groups. In conclusion LPL irradiation have a stimulating effect on the hair growth in the mouse.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.19 no.1
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• pp.13-23
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• 2016

This study was conducted to investigate the growth characteristics of warm-season turfgrasses and to find out suitable turfgrass species on Saemangeum reclaimed land. Twenty native zoysiagrass(Zoysia sinica, Z. matrella, Z. japonica, Medium-leaf type zoysiagrass(hybrid zoysiagrass)) and bermudagrass(Cynodon dactylon) collected from Korea were used in this study. Total stolon length and the number of stolon per square meter, relative growth rate of shoot and stolon, and coverage rate were analyzed for 2 year. C. dactylon showed not only the most growth response with high relative growth rate of shoot and stolon, which were 19.9% and 66.3%, but also resulted in higher level of turf visual quality compared to others. Whereas Z. japonica showed the least growth response with low relative growth rate of shoot and stolon, which were 2.4% and 0.7%. Although all warm-season turfgrasses took root and grew up well, there were different growth rates between the interspecies. Z. sinica 'Z2034', Z. matrella 'Z4091', Z. japonica 'Z1064', Medium-leaf type zoysiagrass 'ZN6019' and C. dactylon 'BN7014' were the greatest growth rate of shoot and stolon. These results will be useful for selecting salt tolerant breeding lines and also used to develop a turfgrass cultivar with strong salinity tolerance through continuous monitoring.

• Korean Journal of Materials Research
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• v.4 no.3
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• pp.357-363
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• 1994

The irradiation growth of the Zircaloy-4 cladding in the KOFA fuel loaded in the Kori-2 nuclear plant was measured to evaluate the irradiation growth behavior and to be compared with that of the Siemens cladding having different manufacturing process. Due to the partial recrystallization by final heat treatment, the KOFA Zircaloy-4 cladding showed a two step irradiation growth behavior such as the growth saturation and the accerlation which is typical of the fully annealed Zircaloy cladding. The difference in the measured irradiation growth rate between the KOFA and the Siemens cladding could be explained by the difference in the cladding texture which depends on the manufacturing process. From the measured irradiation growth data of Kori-2 KOFA fuel, a two-step irradiation growth model of the KOFA Zircaloy-4 cladding was derived, the accuracy of which can be more clearly verified as the measured data of the irradiation growth are accumulated in the future.

• Proceedings of the Korean Society of Toxicology Conference
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• 1997.10a
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• pp.38-42
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• 1997

Human growth hormone is known as one of the peptide hormones which is consisted of 191 amino acids derived from the pituitary gland in humans. The objectives of this study were to supply inexpensive recombinant methionyl human growth hormones (rHGH) synthesized by the DNA technology in a yeast cell line and followed by the establishement of protein purification techniques. The next steps of the research were to study its physic-chemical properties and biological properties, and to evaluate various preclinical aspcts including pharmacokinetics sutdy, general pharmacology study, general toxicity test, and specific toxicity tests. Clinical phase I, II, III studies were also done against growth hormone dficient children to reveal that growth promoting effects were similar compared with the natural HGH extracted from pituitary glands and commercially available rHGHs. The results could be summarized that (I) this yeast dervied rHGH have had excellent physico-chemical and biological properties in comparison with a natural HGH and other synthesized rHGHs, (2) we could not see any toxic side effects when very high doses were administered to the experimental animals, and (3) this growth hormone showed effectiveness in the growth stimulating to growth hormone deficient patients.