• Title/Summary/Keyword: GP5

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Optimizing cement replacement with rice husk ash and eggshell ash for enhanced mechanical properties of geopolymer concrete: A comparative study with and without admixture

  • Yashwanth Pamu;Venkata Sarath Pamu;Praveen Samarthi;Mahesh Kona
    • Computers and Concrete
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    • v.33 no.6
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    • pp.707-724
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    • 2024
  • This paper proposes a study of cement replacement with rice husk ash (RHA) and eggshell ash (ESA) for enhanced mechanical properties of geopolymer (GP) concrete with and without admixture. The main objective is to investigate the mechanical properties of GP with various replacement levels of Pozzolana Portland cement by RHA and ESA. The GP resistance to durability is examined and impact of ash materials on concrete's durability performance is determined. The environmental benefits of using agricultural waste materials in GP manufacturing minimize cement usage and CO2 emissions. The goal is to assess value of RHA-ESA of building material, paving stones for structures to lessen environmental impact. The novelty lies in use of ESA and RHA as partial replacements for cement and investigation of admixtures to enhance concrete properties, and reduce environmental impact. The research contributes by introducing a novel approach to reducing cement consumption by using ESA and RHA to address environmental concerns. It also explores the potential benefits of admixtures improving concrete performance and reducing environmental pollution. A study is carried with and without impacts of admixture to find compressive strength of GP cubes. The cement has been replaced by RHA and ESA in the range of (2.5%+7.5%, 5%+5%, 7.5%+2.5) by weight of cement for M20 mix. The compressive strength (CS) and split tensile strength (STS) at 7days, 14 days and 28 days is obtained as 21 N/mm2 at 7.5%RHA+2.5%ESA and 2.3 at 7.5%RHA+2.5%ESA, 24 N/mm2 at 7.5%RHA+2.5%ESA and 2.3 at 7.5%RHA+2.5%ESA, 28 N/mm2 at 7.5%RHA+2.5%ESA and 2.8 at 7.5%ESA respectively with normal curing condition.

Development of WLAN AP based on IBM 405GP (IBM PowerPC 405GP를 이용한 Wireless LAN Access Point 개발에 관한 연구)

  • Kim Do-Gyu
    • The Journal of Information Technology
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    • v.6 no.3
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    • pp.65-73
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    • 2003
  • The evaluation AP embedded Linux board is implemented. The board is made of IBM 405 GP processor, PPCBoot-1.2.1 boot loader, Linux-2.4.21 kernel and root file system. The evaluation board has two flash memories, boot flash and application flash of size 512Kbyte and 16Mbyte, respectively. And it supports IEEE 802.11a which provide the maximum throughput of 54Mbps in the 5.2GHz frequency band. MTD(Memory Technology Device) and JFFS2(Journalling Flash File System version 2) technologies are adopted to optimally package the system software, boot loader, kernel and root file system. And in order to optimize root file system, busybox package and tiny login are used. Linux kernel and root file system is combined together with mkimage utility.

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Mechanism of P-glycoprotein Expression in the SGC7901 Human Gastric Adenocarcinoma Cell Line Induced by Cyclooxygenase-2

  • Gu, Kang-Sheng;Chen, Yu
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2379-2383
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    • 2012
  • Objective: To investigate possible signal pathway involvement in multi-drug resistant P-glycoprotein (P-gp) expression induced by cyclooxygenase-2 (COX-2) in a human gastric adenocarcinoma cell line stimulated with pacliaxel (TAX). Methods: The effects of TAX on SGC7901 cell growth with different doses was assessed by MTT assay, along with the effects of the COX-2 selective inhibitor NS-398 and the nuclear factor-KB (NF-KB) pathway inhibitor pyrrolidine dithiocarbamate (PDTC). Influence on COX-2, NF-KB p65 and P-gp expression was determined by Western blotting. Results: TAX, NS-398 and PDTC all reduced SGC7901 growth, with dosedependence. With increasing dose of TAX, the expression of COX-2, p65 and P-gp showed rising trends, this being reversed by NS-398. PDTC also caused decrease in expression of p65 and P-gp over time. Conclusion: COX-2 may induce the expression of P-gp in SGC7901 cell line via the NF-kappa B pathway with pacliaxel stimulation.

Molecular cloning and nucleotide sequencing of bovine viral diarrhea virus gp53 antigenic region (소 바이러스성 설사병 바이러스 gp53 항원부위 유전자의 재조합 및 염기서열 연구)

  • Yeo, Sang-geon;Cho, HJ;Masri, SA
    • Korean Journal of Veterinary Research
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    • v.35 no.2
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    • pp.287-295
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    • 1995
  • Molecular cloning and nucleotide sequencing were undertaken for the RNA genome of gp53 antigenic region in cytopathic Singer strain of bovine viral diarrhea virus. The cloned cDNA was 939 nucleotides in length having a base composition of 31.0% A, 19.6% C, 25.5% G and 24.0% T. The sequence was corresponded to approximately 77.8%(817 bases) of predicted gp53 region and 122 bases after 3'end of gp53 region in the Singer strain when compared with NADL strain of known sequence. A single open reading frame was found in the sequence of 2nd frame and was deduced as encoding 312 amino acids.

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물리적, 화학적 방법으로 환원된 그라핀의 분자구조

  • Ju, Hye-Mi;Choi, Seong-Ho;Cho, Kwang-Yeon;Kim, Chang-Yeoul;Hyun, Sang-Il;Huh, Seung-Hun;Lee, Hong-Lim
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2009.11a
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    • pp.31.2-31.2
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    • 2009
  • 본 연구에서는 Graphene oxide를 $800^{\circ}C$, 질소분위기 하에서 환원시켜 얻은 $GP_{TR}$과 Hydrazine을 이용한 화학적 처리로 얻은 $GP_{CR}$의 분자구조를 제안하였다. 이때 grapheneoxide는 modified Hummers' method를이용하여 제조하였다. $GP_{TR}$$GP_{CR}$은 모두 표면에 몇몇의 oxide group이 존재하는데$GP_{TR}$은 six layer로 $C_{100}O_{3{\pm}1}$ 의 조성을 갖고 $GP_{CR}$은 three layer로 and $C_{100}O_{6.5{\pm}2}$의 조성을 갖는다. 그리고 면간간격은 $GP_{TR}$$3.432\;{\AA}$, $GP_{CR}$$3.760\;{\AA}$으로 전형적인 방법인 top downprocess로 얻은 graphene 보다 다소 크다는 것을 알 수 있다.

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Adsorption of Hydrophobic Fluid by Polyurethane Foam (폴리우레탄 폼을 이용한 친유성 유체의 흡착)

  • Chai, Joo-Byung;Kim, Byung-Kyu;Shin, Young-Jo
    • Applied Chemistry for Engineering
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    • v.9 no.5
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    • pp.648-653
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    • 1998
  • This study examines the effects of cell size and structure on the oil adsorption by polyurethane (PU) foam. A series of oil-adsorptive PU foam has been prepared, using various molecular weight of polyether polyol (GP-1000, GP-3000, GP-4000, GP-5000), together with TDI-80, water and additives. It was found that the cell size of PU foam decreased with increasing the agitation speed and surfactant content. Oil-adsotption of PU foam increased over 2000% with the increase of molecular weight of polyol and with the decrease of cell size. Increase in the surfactant content and the viscosity of adsorbed oil also give a remarkable decrease in oil adsorption.

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Assessment of decontamination of gutta-percha cone and the change of surface texture after rapid chemical disinfection (화학소독제 처리 후 가타파차 콘의 멸균 효과 및 표면 성상의 변화 평가)

  • Pang, Nan-Sim;Jung, Il-Young;Yu, Yoon-Jung;Kum, Kee-Yeon
    • Restorative Dentistry and Endodontics
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    • v.31 no.2
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    • pp.133-139
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    • 2006
  • The purposes of this study were firstly to identify the microbial species on gutta-percha (GP) cones exposed at outpatient clinics using polymerase chain reaction, and secondly to evaluate the rapid sterilization effect of two chemical disinfectants at chair side. It also evaluated the alteration of surface texture of GP cones after 5-min soaking into two chemical disinfectants. A total of 100 GP cones from two endodontic departments were randomly selected for microbial detection using PCR assay with universal primer. After inoculation on the sterilized GP cones with the same microorganism identified by PCR assay, they were soaked in two chemical disinfectants: 5% NaOCl and 2% chlorhexidine for 1, 3, 5, and 10 minutes. The sterilization effect was evaluated by turbidity and subculture. The change of surface textures using a scanning electron microscope was also examined after 5 min-soaking in two chemical disinfectants. Results showed that four bacterial species were detected in 17 GP cones, and all the species belonged to the genus Staphylococcus. Two chemical disinfectants were effective in sterilization with just 1 minute soaking. On the SEM picture of NaOCl-soaked GP cone, a cluster of cuboidal crystals was seen on the cone surface. Present data demonstrate that two chemical disinfectants are useful for rapid sterilization of GP cone just before obturation at chair side, while CHX-soaked GP cone has cleaner surface without crystal precipitation than that of NaOCl-treated cone.

Ameliorating Effects of the Ethanol Extracts from Gynostemma pentaphyllum on Electric Footshock Stress (돌외 에탄올 추출물 엑스의 전기쇼크 스트레스 저항력 개선작용)

  • Choi, Hyun-Sook;Lim, Seon-A;Park, Mi-Sook;Hwang, Bang-Yeon;Lee, Chong-Kil;Kim, Seung-Hwan;Lim, Sung-Cil;Lee, Myung-Koo
    • Korean Journal of Pharmacognosy
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    • v.39 no.4
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    • pp.341-346
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    • 2008
  • The effects of the ethanol extracts from Gynostemma pentaphyllum (GP extracts) on body weights, grip strengths, endurances and catecholamine levels after electric footshock (EF) stress in mice and rats were investigated. The animals were treated with GP extracts (50 mg/kg/day, p.o.) for 21 days before exposure to EF (duration and interval 10 sec for 3 min, 2 mA) once a day. The increases in body weights were delayed by 13.1% of the control levels by EF-induced stress in mice, which were recovered to 24.1% of the control levels in GP extract-treated groups. The grip strengths were significantly decreased by EF stress in mice and the EF-stressed groups treated with GP extracts increased grip strengths to 115.2% compared to control levels. The endurance times by forced swimming, which reduced significantly by EF stress, were also maintained similar to control levels by GP extracts in rats. In addition, the levels of norepinephrine and epinephrine in serum and brain, and dopamine in brain were significantly increased to 17.5-95.0% of the control levels after exposure of EF stress in mice. However, EF stressinduced increases in norepinephrine and epinephrine in serum were reduced to 17.1-17.3% of the control levels by treatments of GP extracts, and those in dopamine, norepinephrine and epinephrine in brain were also reduced to 5.0-19.5%. These results suggest that GP extracts showed the protective effects on EF stress-induced physiological functions and can be developed as the promising anti-stress agents.

Single-dose Toxicity of Water-soluble Ginseng Pharmacopuncture Injected Intramuscularly in Rats

  • Yu, Junsang;Sun, Seungho;Lee, Kwangho;Kwon, Kirok
    • Journal of Pharmacopuncture
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    • v.18 no.2
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    • pp.76-85
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    • 2015
  • Objectives: Radix Ginseng has been traditionally used as an adaptogen that acts on the adrenal cortex and stimulates or relaxes the nervous system to restore emotional and physical balance and to improve well-being in cases of degenerative disease and/or old age. Radix Ginseng has been used for a long time, but the safety of ginseng pharmacopuncture needs testing. This study was done to analyze the single-dose toxicity of water- soluble ginseng pharmacopuncture (GP) intramuscular injections in rats. Methods: All experiments were performed at Biotoxtech, an institution authorized to perform non clinical studies under the regulations of Good Laboratory Practice (GLP). Each group contained 10 Sprague-Dawley rats, 5 males and 5 females. GP was prepared in a sterile room at the Korean Pharmacopuncture Institute under regulations of Good Manufacturing Practice (GMP). GP dosages were 0.1, 0.5 and 1.0 mL for the experimental groups; normal saline was administered to the control group. The animals general condition was examined daily for 14 days, and the rats were weighed on the starting day and at 3, 7 and 14 days after administration of the pharmacopuncture. Hematological and biochemistry tests and autopsies were done to test the toxicological effect of GP after 14 days. This study was performed with approval from the Institutional Animal Ethics Committee of Biotextech. Results: No deaths were found in this single-dose toxicity test of intramuscular injections of GP, and no significant changes in the general conditions, body weights, hematological and biochemistry tests, and autopsies were observed. The local injection site showed no changes. Based on these results, the lethal dose was assumed to be over 1.0 mL/animal in both sexes. Conclusion: These results suggest that GP is relatively safe. Further studies, including a repeated toxicity test, are needed to provide more concrete evidence for the safety of GP.

Effects of GP extract on oxidative stress and contact dermatitis in NC/Nga Mice induced by DNCB (가감평위산(加減平胃散)이 산화적 손상과 접촉성 피부염에서의 면역 조절작용에 미치는 영향)

  • Park, Eung-Ho;Yun, Mi-Young;Kim, Seon-Bin;Kim, Dong-Hee
    • Journal of Haehwa Medicine
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    • v.16 no.2
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    • pp.131-145
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    • 2007
  • To evaluate the effects of GP on contact dermatitis, we examined the composition of immune cells from drain lymph node in DNCB-induced contact dermatitis murine model NC/Nga mice. And the amount of pathologic cytokines of spleen and antioxidant activity were investigated. The results were summarized as followers; 1. GP did not show cytotoxic effect on mLFC in vitro. 2. GP did not have hepatotoxicity in vivo in the level of ALT, AST. 3. GP decreased the production of DPPH and in a dose-dependent. 4. GP significantly decreased total cell number of DLN in DNCB-induced NC/Nga mice compared to the untreated control group. 5. GP significantly decreased the number of CD3+, CD19+, CD4+, CD8+, CD3+/CD69+ and CD4+/CD45+ in DLN of DNCB-induced NC/Nga mice compared to the untreated control group. 6. GP significantly reduced the level of IL-4 and IFN-$\gamma$ in splenocytes of DNCB-induced NC/Nga mice compared to the untreated control group. Taken together above results, GP have therapeutic effects on contact dermatitis by regulating T cell activation. This study warranted further investigations of molecular mechanisms of GP on contact dermatitis.

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