• Title/Summary/Keyword: GN

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Connected geodesic number of a fuzzy graph

  • Rehmani, Sameeha;Sunitha, M.S.
    • Annals of Fuzzy Mathematics and Informatics
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    • v.16 no.3
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    • pp.301-316
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    • 2018
  • In this paper, the concept of connected geodesic number, $gn_c(G)$, of a fuzzy graph G is introduced and its limiting bounds are identified. It is proved that all extreme nodes of G and all cut-nodes of the underlying crisp graph $G^*$ belong to every connected geodesic cover of G. The connected geodesic number of complete fuzzy graphs, fuzzy cycles, fuzzy trees and of complete bipartite fuzzy graphs are obtained. It is proved that for any pair k, n of integers with $3{\leq}k{\leq}n$, there exists a connected fuzzy graph G : (V, ${\sigma}$, ${\mu}$) on n nodes such that $gn_c(G)=k$. Also, for any positive integers $2{\leq}a<b{\leq}c$, it is proved that there exists a connected fuzzy graph G : (V, ${\sigma}$, ${\mu}$) such that the geodesic number gn(G) = a and the connected geodesic number $gn_c(G)=b$.

Introducing the general management of glomerular disease from a pediatric perspective based on the updated KDIGO guidelines

  • Seon Hee Lim
    • Childhood Kidney Diseases
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    • v.27 no.2
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    • pp.55-63
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    • 2023
  • In 2021, a new chapter on the general management of glomerulonephritis (GN) was added to the Kidney Disease: Improving Global Outcomes (KDIGO). It emphasizes the importance of early general management of GN for improving long-term kidney outcomes and prognosis. The chapter introduces the management of glomerular diseases in 18 subchapters. Here, kidney biopsy for the diagnosis and evaluation of kidney function and the management of complications, such as hypertension, infection, and thrombosis, are presented. Moreover, the adverse effects of glucocorticoids and immunosuppressive therapy, which are commonly used drugs for glomerular disease, are mentioned, and a guideline for drug selection is presented. Each subtheme focused on items reflecting the interpretation of the "practice points" of the expert working group are introduced. In this review of the general treatment for GN in the KDIGO guidelines, excluding pregnancy and reproductive health, we focused on and compared various references pertaining to pediatric GN management.

Pulsatile GnRH Therapy in Male Patients with Hypogonadotropic Hyprogonadism (GnRH의 맥동성 투여에 의한 남성 성선기능저하증의 치료)

  • Park, Ki-Hyun;Jee, Yong-Seok;Lee, Byung-Seok;Lee, Bo-Yun;Cho, Dong-Jae;Song, Chan-Ho;Lee, Moo-Sang;Choi, Hyung-Ki;Lee, Hyun-Chul;Heo, Kab-Beom
    • Clinical and Experimental Reproductive Medicine
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    • v.19 no.1
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    • pp.81-85
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    • 1992
  • The effects of pulsatile GnRH therapy have been studied for the treatment of different forms of hypogonadotropic hypogonadism, including idiopathic hypogonadotropic hypogonadism and hypogonadism developed as a result of treatment with combination of surgery and irradiation for pituitary or hypothalamic tumor. GnRH was administered subcutaneously in a dose of $10{\mu}g$ every 2 hours with the pulsatile infusion pump. With GnRH therapy, all patients improved secretion of LH, FSH and testosterone. Testicular volumes increased. Spermatogenesis was induced in 8 patients. Pulsatile GnRH therapy is an effective treatment for idiopathic hypogonadotropic hypogonadism and can have a role in hypogonadism previously treated with combination of surgery and irradiation for pituitary or hypothalamic tumor.

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Comparison of Enrichment Media of Shigella sonnei (쉬겔라 증균배지의 성능 비교)

  • In, Ye-Won;Ha, Su-Jeong;Kim, Seok-Joong;Oh, Se-Wook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.12
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    • pp.1787-1792
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    • 2011
  • The object of this study was to compare the performance of commercial enrichment media used for Shigella spp. A total of four enrichment media, Gram negative (GN) broth, Shigella broth (SB), selenite-F (SF) broth, and selenite cystine (SC) broth, were tested. When S. sonnei was inoculated into each enrichment broth at 10 cfu/mL of concentration, the highest growth was observed in Shigella broth. Morganella spp., which was not differentiated in selective agar of Shigella spp. thus can be counted as false positive, did not grow in Shigella broth in enrichment step. When S. sonnei was artificially inoculated into pork, it was mostly recovered through an enrichment process with GN broth and SF broth. However, in the case of beef, S. sonnei was mostly recovered with GN broth but largely failed with Shigella broth. Therefore, enrichment media for Shigella spp. should be selected by considering the food matrix in order to increase the chance of isolating it from foods.

A longitudintal study of soft-tissue profile changes In korean adults aged from 24 to 32 years (성인의 연조직 측모 변화)

  • Hwang, Sang-Hee;Sung, Jae-Hyun
    • The korean journal of orthodontics
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    • v.30 no.1 s.78
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    • pp.101-114
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    • 2000
  • The purpose of this study was to evaluate the soft-tissue profile changes from 24 to 32 yews of age in Korean adults. The subjects used in this study consisted of 17 males and 8 females. The data obtained from the lateral cephalograms taken at age 24 and 32, were analyzed statistically. The obtained results were as follows : 1. During the observation period, there were no significant changes in the hard-tissue measurements in both sexes (p>0.05). 2. In the anteroposterior measurements of soft-tissue, the males had significant increase in chin area (Pog', Gn'), and the females had significant decrease in lower lip (LI) (p<0.05). 3. In the vertical measurements of soft-tissue, both sexes showed the increased tendency in upper lip length (Sn-Sto) where the males showed significant increase (p<0.05). The lower facial height (Sn-Gn') turned out significant increase in both sexes (p<0.05). 4. In general, the females and males had the increased tendency in soft-tissue thickness, especially significant increase in chin area (Pog', Gn') (p<0.05).

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Changes of Hypothalamic GnRH-I, POMC and NPY mRNA Expression and Serum IGF-I and Leptin Concentrations during Maturation of Shaoxing Ducks (Anas platyrhynchos)

  • Ni, Y.;Lu, L.;Chen, J.;Zhao, Ruqian
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.9
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    • pp.1211-1216
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    • 2011
  • Sexual maturity in poultry is controlled by a complex neural circuit located in the basal forebrain, which integrates the central and peripheral signals to activate hypothalamic gonadotrophin-releasing hormone (GnRH) secretion. This study demonstrated the changes of GnRH-I, POMC and NPY mRNA transcription in hypothalamus and IGF-I and leptin levels in serum of Shaoxing ducks during puberty. Body weight increased progressively from d30 to d120 and at d120 the flock reached 5% of laying rate. A significant upregulation of hypothalamic GnRH-I mRNA expression was observed from d60, reaching the peak at d120. POMC and NPY mRNA expression in hypothalamus showed a similar pattern, which increased from d30 to d60, followed by a significant decrease towards sexual maturity. Serum IGF-I levels exhibited two peaks at d30 and d120, respectively. Serum leptin displayed a single peak at d90. The results indicate that the down-regulation of POMC and NPY genes in hypothalamus coincides with the up-regulation of GnRH-I gene to initiate sexual maturation in ducks. In addition, peripheral IGF-I and leptin may relay the peripheral metabolic status to the central system and contribute to the initiation of the reproductive function in ducks.