• Title/Summary/Keyword: GLS

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Changes in Cardiac Structure and Function After Kidney Transplantation: A New Perspective Based on Strain Imaging

  • Darae Kim;Minjeong Kim;Jae Berm Park;Juhan Lee;Kyu Ha Huh;Geu-Ru Hong;Jong-Won Ha;Jin-Oh Choi;Chi Young Shim
    • Journal of Cardiovascular Imaging
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    • v.31 no.2
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    • pp.98-104
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    • 2023
  • BACKGROUND: We aimed to investigate left ventricular (LV) global longitudinal strain (GLS) in end-stage renal disease patients and its change after kidney transplantation (KT). METHODS: We retrospectively reviewed patients who underwent KT between 2007 and 2018 at two tertiary centers. We analyzed 488 patients (median age, 53 years; 58% male) who had obtained echocardiography both before and within 3 years after KT. Conventional echocardiography and LV GLS assessed by two-dimensional speckle-tracking echocardiography were comprehensively analyzed. Patients were classified into three groups according to the absolute value of pre-KT LV GLS (|LV GLS|). We compared longitudinal changes of cardiac structure and function according to pre-KT |LV GLS|. RESULTS: Correlation between pre-KT LV EF and |LV GLS| were statistically significant, but the constant was not high (r = 0.292, p < 0.001). |LV GLS| was widely distributed at corresponding LV EF, especially when the LV EF was > 50%. Patients with severely impaired pre-KT |LV GLS| had significantly larger LV dimension, LV mass index, left atrial volume index, and E/e' and lower LV EF, compared to mildly and moderately reduced pre-KT |LV GLS|. After KT, the LV EF, LV mass index, and |LV GLS| were significantly improved in three groups. Patients with severely impaired pre-KT |LV GLS| showed the most prominent improvement of LV EF and |LV GLS| after KT, compared to other groups. CONCLUSIONS: Improvements in LV structure and function after KT were observed in patients throughout the full spectrum of pre-KT |LV GLS|.

Response of Turnip to Botrytis cinerea Infection and Their Relationship with Glucosinolate Profiles (잿빛곰팡이병에 대한 순무잎의 반응과 Glucosinolate 함량변화)

  • Kwon, Soon-Tae;Kliebenstein, Daniel J.
    • Korean Journal of Plant Resources
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    • v.27 no.4
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    • pp.371-379
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    • 2014
  • In order to determine the response of turnip leaves to various races of Botrytis cinerea, fourteen different races were infected to the leaf surface and measured the lesion size. Based on lesion size of the pathogen on the leaves, turnip showed susceptible response to four races, moderate to seven races and resistant to three races. Four glucosinolate (GLS) compounds, such as butenyl GLS, indole-3ylmethyl GLS (I3M), 4-methoxy-indole-3-ylmethyl GLS (4MOI3M) and normal methoxy-indole-3ylmethyl GLS (NMOI3M) were identified in turnip leaves infected with Botrytis cinerea. Leaves infected with resistant races showed higher GLS contents as compared with the leaves infected with susceptible races. Contents of I3M in the leaves with resistant races were 2.5 times as high as those in uninfected leaves, whereas I3M in the leaves with susceptible races showed lower contents than those in untreated leaves. Leaves infected with resistant races showed 4MOI3M and NMOI3M contents 2.3 and 2.7 times as high as those in uninfected leaves, respectively. GLSs in the infected leaves were most abundant at 5~10 mm area from center of the lesion. However, the GLSs in 5~10 mm area were rapidly degradated at leaves with susceptible races which resulted in continuous expansion of the lesion on the leaves, whereas no degradation was obseveved at leaves with resistant races. These results suggest that accumulation and degradation of GLS compounds in turnip leaves closely related to the susceptibility and resistance of turnip leaves to Botrytis races.

The Effects of GLS(Gleditsiae spina) Treatment on Hematological and Cytopathological Alterations in Non-Bacterial Prostatitis Rat Model (조각자가 만성 비세균성 전립선염 Rat 모델에서 혈액 및 세포조직의 변화에 미치는 영향)

  • Jung, Gi-Hun;Chang, Sun-Kyu;Choi, Jung-Sik;Cho, Chung-Sik;Kim, Chul-Jung
    • The Journal of Internal Korean Medicine
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    • v.28 no.4
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    • pp.779-790
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    • 2007
  • Objective : Although chronic non-bacterial prostatitis is a common disease, it is very difficult to treat effectively. GLS (Gleditsiae Spina) has traditionally been used in treatment of urinary tract inflammation and voiding disturbance. In this study, we investigated the therapeutic effects and action mechanism of GLS in the rat model of non-bacterial prostatitis induced by castration and testosterone treatment. Method : We observed four experimental objects of normal group, control group, testosterone group, and GLS group. Rats were treated with 17$\beta$-estradiol after castration for induction of experimental non-bacteral prostatitis, which is similar to human chronic prostatitis in histophatological profiles. GLS and testosterone were administered as an experimental specimen and a positive control, respectively. The prostates were evaluated by histopahological parameters including the epithelial score and epithelio-stromal ratio for glandular damage. Also, the prostates were observed by hematological alterations of WBC, RBC, hemoglobin, hematocrit and platelet. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with GLS showed a diminished range of tissue damage. Epithelial score was improved in GLS over that of the control. The epithelial-stromal ratio was lower in GLS when compared to that of the control. Conclusion : These findings suggest that GLS may protect the glandular epithelial cells. We concluded that GLS could be a useful remedy agent for treating chronic non-bacterial prostatitis.

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Integrated Group Location Tracking Scheme and Its Performance Evaluation for Public Transportation Systems in Mobile Communication Networks (이동통신망에서 대중교통을 위한 통합 그룹위치등록 방법 및 성능 평가)

  • Seo, Jae-Young;Baek, Jang-Hyun
    • IE interfaces
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    • v.22 no.2
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    • pp.185-191
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    • 2009
  • In this study, we propose an improved group location tracking scheme (GLS) called integrated GLS (IGLS) which, in addition to the group location registration of the GLS, sends an integrated group registration message to a virtual visitor location register (VVLR) instead of sending an individual group registration message. This integrated procedure of proposed scheme leads registration cost of group registration and group location registration to be reduced significantly. Numerical results demonstrate that our proposed IGLS outperforms conventional GLS and delayed GLS (dGLS). The IGLS can be applied effectively on public transportation systems such as subway, train and bus.

A Study on a Flood Frequency Analysis Guideline for Korea (국내 홍수빈도해석 지침서 수립을 위한 연구)

  • Kim, Young-Oh;Sung, Jang-Hyun;Seo, Seung-Beom;Lee, Kyoung-Teak
    • 한국방재학회:학술대회논문집
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    • 2010.02a
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    • pp.53.2-53.2
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    • 2010
  • 국내 홍수빈도해석 지침서 제공을 위한 기초 연구로서 미국 홍수빈도해석 지침서인 Bulletin 17B과 같이 국내 적합한 홍수빈도해석 기법을 제시하고자 하였다. 홍수빈도해석 지침서의 핵심은 확률분포형과 매개변수 추정법을 제시하는 것이며 이에 GEV(Generalized Extreme Value), GLO(Generalized Logistic) 분포, B-GLS(Bayesian Generalized Least Square) 기법을 대상으로 다양한 연구를 수행하였다. B-GLS 기법을 이용하여, 국내 대유역에 골고루 위치하며 댐의 영향을 받지 않는 31개 지점의 연최대 일유량 시계열의 L-변동계수(L-moment coefficient variation)와 L-왜도계수(L-moment coefficient skewness)를 추정할 수 있는 회귀모형을 제안하였다. 위 회귀모형을 구성하기 위한 유역특성으로는 유역면적, 유역경사, 유역평균강우 등을 사용하였다. Bayesian-GLS(B-GLS) 적용 결과를 OLS(Ordinary Least Square) 및 B-GLS 기법에서 지점간의 상관관계를 고려하지 않는 Bayesian-WLS(Weighted Least Square)와 비교 평가하여 그 우수성을 입증하였다. 따라서 본 연구에서 제안된 B-GLS에 의한 지역회귀모형은 국내의 미계측유역이나 또는 관측 길이가 짧은 계측유역의 홍수빈도분석을 위해 매우 유용할 것으로 기대된다. 또한 수행된 연구의 내용을 공론화하는 노력이 계속된다면 공감대가 형성된 가이드라인을 제정되는데 일조를 하리라 확신한다.

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QTL Mapping of Resistance to Gray Leaf Spot in Ryegrass: Consistency of QTL between Two Mapping Populations

  • Curley, J.;Chakraborty, N.;Chang, S.;Jung, G.
    • Asian Journal of Turfgrass Science
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    • v.22 no.1
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    • pp.85-100
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    • 2008
  • Gray leaf spot (GLS) is a serious fungal disease caused by Pyricularia oryzae Cavara, recently reported on the important turf and forage species, perennial ryegrass (Lolium perenneL.). This fungus also causes rice blast, which is usually controlled by host resistance, but durability of resistance is a problem. Few instances of GLS resistance have been reported in perennial ryegrass. However, two major QTL for GLS resistance have been detected on linkage groups 3 and 6 in an Italian x perennial ryegrass mapping population. To confirm that those QTL are still detectable in the next generation and can function in a different genetic background, a resistant segregant from this population has been crossed with an unrelated susceptible perennial clone, to form a new mapping population segregating for GLS resistance. QTL analysis has been performed in the new population, using two different ryegrass field isolates and RAPD, RFLP, and SSR marker-based linkage maps for each parent. Results indicate the previously identified QTL on linkage group 3 is still significant in the new population, with LOD and percent of phenotypic variance explained ranging from 2.0 to 3.5 and 5% to 10%, respectively. Also two QTL were detected in the susceptible parent, with similar LOD and phenotypic variance explained. Although the linkage group 6 QTL was not detected, the major QTL on linkage group 3 appears to beconfirmed. These results will add to our understanding of the genetic architecture of GLS resistance in ryegrass, which will facilitate its use in perennial ryegrass breeding programs.

Anti-aging & Skin Hydration Effects of Spore oil Extracted from Ganoderma lucidum (영지버섯에서 추출한 포자오일의 항노화 및 보습 효능)

  • Song, Hwan;Kim, Myun Soo
    • Journal of Convergence for Information Technology
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    • v.10 no.5
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    • pp.232-238
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    • 2020
  • This study evaluated the anti-aging activity with antioxidant, anti-inflammatory and moisture activity of Ganoderma lucidum spore oil(GLS). GLS increased DPPH radical scavenging activity in a dose-dependent manners. Anti-inflammatory assay measured the inhibitory effect of GLS on NO, TNF-α and IL-6 production in LPS-stimulated RAW264.7 cells. As a result GLS inhibited NO and pro-inflammatory cytokine, TNF-α, IL-6 production. Also using human fibroblast cell to the procollagen production analysis and COL1A1 mRNA expression level analysis for defining, and for AQP-3 mRNA expression level analysis, used human keratinocyte cell. GLS increased procollagen production and COL1A1, AQP-3 mRNA expression. Our results suggest that the GLS have potential anti-inflammatory and wrinkle improves, skin moisture effect.

Effectiveness of Logistics information Systems for RFID - Focusing on CJ GLS Co. Case - (RFID를 이용한 물류정보시스템의 구축효과 -CJ GLS 사례를 중심으로-)

  • Kim, Moon-jung
    • Journal of Distribution Science
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    • v.5 no.2
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    • pp.79-100
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    • 2007
  • CJ GLS Co. builds successfully Warehouse Management Systme (WMS), Customer Service & Support System(CSS), and Delivery Management System using RFID. This study tris to find out the effectiveness in CJ case. RFID, the core technology of Ubiquitous network, is now implied in our policy by the Ministry of Commerce, Industry & Energy. To support the study, examples from Korea and other countries using RFID system were introduced. Examples include the definition and features of RFID and the current applications of RFID. CJ GLS Co. used RFID to build the Integrated Logistics Management System effectively. The study analyzed the background of why to use this system, the goals and objectives of system building and the effectiveness of system building. In conclusion, the future of RFID and SCM was presented.

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