• Korean Architects
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• no.2 s.120
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• pp.47-56
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• 1979

• Proceedings of the KIPE Conference
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• 2016.07a
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• pp.361-362
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• 2016

Presented in this paper is the design of a high voltage switch module made up of MOSFETs, pulse transformers and their gate driver circuits compactly fitted onto a single PCB module. The ease by which the switch modules can be configured (series stacking and/or parallel stacking) to meet future load variations allows for flexible operation of this design. In addition, the detailed implementation of the gate driver circuit for reliable and easier switch synchronization is also described in this paper. The stored energy in the capacitor bank of a 15kV, 4.5kJ/s peak power capacitor charger was discharged using the developed high voltage switch, and by experimental results, the operation of the proposed circuit was verified to be effectively used as a switch for pulse discharging.

• Proceedings of the KIPE Conference
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• 2016.07a
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• pp.56-57
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• 2016

본 논문은 LCC 공진형 컨버터를 기반으로 설계된 15kV, 1.5kJ/s 고전압 커패시터 충전기에 대하여 기술한다. 연속도전모드에서 동작하는 LCC 공진형 컨버터 설계를 통해 영전압 스위칭을 구현하고, 공진전류를 사다리꼴 형태로 개선하여 도전손실을 줄일 수 있도록 공진 파라메터를 설계 한다. 승압을 위한 고주파, 고전압 변압기를 다수의 환형 코어를 이용하여 설계하여 효율적인 기중절연을 확보하였다. 제작된 고전압 커패시터 충전기 프로토 타입의 저항부하 정격운전 및 커패시터 충전 실험을 통해 설계를 검증 하였다.

• Proceedings of the KIPE Conference
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• 2016.07a
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• pp.259-260
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• 2016

본 논문은 30kW, 95GHz 자이로트론 구동을 위한 전원 시스템 설계 및 실험에 대하여 기술한다. 효율적인 자이로트론 구동을 위해 개발된 아래 사양의 세 전원장치의 상세 설계, 제작 및 저항부하 실험결과를 제시한다. - Cathode Power Supply (CPS: 50kV, 100kW) - Body Power Supply (BPS: 25kV, 250W) - Heater Power Supply(HPS: 10V, 10A, 50kV Isolation) 또한 현재 수행 중인 자이로트론 구동 실험결과를 통해 개발된 전원장치의 성능을 검증한다.

• Journal of the Korean Institute of Intelligent Systems
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• v.2 no.2
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• pp.3-33
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• 1992

The successful application of fuzzy reasoning models to fuzzy control systems depends on a number of parameters, such as fuzzy membership functions, that are usually decided upon subjectively. It is shown ill this paper that the performance of fuzzy control systems call be improved if the fuzzy reasoning model is supplemented by a genetic-based learning mechanism. The genetic algorithm enables us to generate all optimal set of parameters for the fuzzy reasoning model based either on their initial subjective selection or on a random selection. It is shown that if knowledge of the domain is available, it is exploited by the genetic algorithm leading to an even better performance of the fuzzy controller.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1993.06a
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• pp.1297-1300
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• 1993

Machine learning in an uncertain or unknown environment is of vital interest to those working with intelligent systems. The ability to garner new information, process it, and increase the understanding/ capability of the machine is crucial to the performance of autonomous systems. The field of artificial intelligence provides two major approaches to the problem of knowledge engineering-expert systems and neural networks. Harnessing the power of these two techniques in a hybrid, cooperating system holds great promise.

• Proceedings of the KIPE Conference
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• 2016.07a
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• pp.167-168
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• 2016

본 논문은 고효율 반도체 기반 펄스 전원 장치 개발에 대해 기술한다. 개발 된 펄스 전원장치는 출력 전압 1-40kV, 펄스 반복율 1-200Hz, 펄스폭 1-300us, 정격 출력 50kW의 사양을 가지고 있다. 제안하는 펄스 전원 장치는 크게 출력 커패시터를 충전하여 고전압을 만드는 충전기 부분과 48개의 IGBT가 직렬로 연결되어 펄스를 만들어 내는 펄스 제네레이터 부분으로 나누어져 있다. 펄스 제네레이터는 파워셀 기반으로 구성되어, IGBT간의 전압 밸런싱 및 IGBT의 동기구동 실패시에 신뢰성 있는 동작을 할 수 있다는 장점을 가지고 있다. 또한, 제안된 펄스 전원 장치는 새로운 게이트 구동회로를 사용하여 기존에 사용하던 풀다운 저항을 제거하고, 빠른 펄스 하강 시간을 달성 하였다. 개발된 펄스 전원장치로 실험을 수행한 결과, 커패시터 충전기는 최대 충전효율 95% 및 역률 96%를 나타냈으며, 펄스 제너레이터는 게이트 구동회로가 안정적으로 동작하며 최대 40kV, 300us의 펄스를 $2k{\Omega}$ 부하에 인가 가능함을 확인하였다.

• Journal of Microbiology
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• v.35 no.4
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• pp.347-353
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• 1997

We have characterized a phage library displaying random 22mer peptides which were produced as N-terminal fusions to the pIII coat protein of M13 filamentous phages. Among the sixty phages randomly picked from the library, 25 phages had the 22mer peptide inserts. The DNA sequence analysis of the 25 inserts showed the following results: first, each nucleotide was represented almost equally at each codon position except that there were some biases toward G bases at the first position of the codons. Secondly, the expected 47 sense codons were represented. The deduced amino acid sequences of the 25 inserts were analyzed to examine its diversity. Glycine and glutamate were the two most overrepresented residues above the expected value, whereas cysteine and threonine residues were underrepresented. The range of dicersity in dipeptide sequences showed that the amino acid residues were randomly distributed along the peptide insert. Acidic, basic, polar, and nonpolar amino acid residues were represented to the extent expected at most positions of the peptide inserts. The predicted isoelectric points and hydropathy indices of the 25 peptides showed that a variety of the peptide were represented in the library. These results indicate that this phage display library could be useful in fiuding ligands for a broad spectrum of receptors by affinity screening.

• Journal of Animal Science and Technology
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• v.59 no.5
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• pp.12.1-12.7
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• 2017

Background: Despite the widespread use of dexamethasone in veterinary and human medicine, it is reported to cause some severe pregnancy related side effects like abortion in some animals. The mechanism of the response is not clear but seems to be related to interspecies and/or breed difference in response which may involve alterations in the concentrations of some reproductive hormones. Methods: Twenty Sahel goats comprising 18 does and 2 bucks were used for this study. Pregnancies were achieved by natural mating after synchronization. Repeated dexamethasone injections were given at 0.25 mg/kg body weight. Blood samples were collected biweekly for hormonal assay. Uterine biopsies were harvested at days 28 and day 78 of gestation through caesarean section for immunohistochemical analysis using 3 pregnant does randomly selected from each group at each instant. Data were expressed as Means ${\pm}$ Standard Deviations and analyzed using statistical soft ware package, GraphPad Instant, version 3.0 (2003) and progesterone receptor (PR) were scored semi-quantitatively. Results: Dexamethasone treatments had no significant (p > 0.05) effect on progesterone and estrogen concentrations in pregnant Sahel goats but up regulated PR from 2+ to 3+ in second trimester. Conclusion: As dexamethasone adverse effect on placenta is an established fact, the lack of effect on progesterone level in this study may be due to the fact that unlike other species whose progesterone production during pregnancy is placenta - dependent, in goats is corpus luteum - dependent. Consequently dexamethasone adverse effect on placenta reported in literatures did not influence progesterone levels during pregnancy in Sahel goat. The up regulation of progesterone receptor (PR) in Sahel goat gravid uterus is a beneficial effects and that dexamethasone can safely be used in corpus luteum - dependent progesterone secreting pregnant animal species like Sahel goat and camel. Therefore source of progesterone secretions during pregnancy should be considered in clinical application of dexamethasone in pregnancy.

• Annals of Occupational and Environmental Medicine
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• v.35
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• pp.39.1-39.14
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• 2023

Background: Diseases affecting the lungs and airways contribute significantly to the global burden of disease. The problem in low- and middle-income countries appears to be exacerbated by a shift in global manufacturing base to these countries and inadequate enforcement of environmental and safety standards. In Ghana, the potential adverse effects on respiratory function associated with occupational wood dust exposure have not been thoroughly investigated. Methods: Sixty-four male sawmill workers and 64 non-woodworkers participated in this study. The concentration of wood dust exposure, prevalence and likelihood of association of respiratory symptoms with wood dust exposure and changes in pulmonary function test (PFT) parameters in association with wood dust exposure were determined from dust concentration measurements, symptoms questionnaire and lung function test parameters. Results: Sawmill workers were exposed to inhalable dust concentration of 3.09 ± 0.04 mg/m³ but did not use respirators and engaged in personal grooming habits that are known to increase dust inhalation. The sawmill operators also showed higher prevalence and likelihoods of association with respiratory symptoms, a significant cross-shift decline in some PFT parameters and a shift towards a restrictive pattern of lung dysfunction by end of daily shift. The before-shift PFT parameters of woodworkers were comparable to those of non-woodworkers, indicating a lack of chronic effects of wood dust exposure. Conclusions: Wood dust exposure at the study site was associated with acute respiratory symptoms and acute changes in some PFT parameters. This calls for institution and enforcement of workplace and environmental safety policies to minimise exposure at sawmill operating sites, and ultimately, decrease the burden of respiratory diseases.