• Title/Summary/Keyword: GCT

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Analysis for Usefulness of Arterial Embolization on Sacral and Pelvic Giant Cell Tumors (천골 및 골반골에 발생한 거대세포종에 대한 동맥 색전술 치료의 효용성 분석)

  • Kim, Seung Hyun;Yoon, Gil Sung;Cho, Yong Jin;Shin, Kyoo-Ho;Suh, Jin-Suck;Yang, Woo-Ick
    • The Journal of the Korean bone and joint tumor society
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    • v.19 no.2
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    • pp.50-55
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    • 2013
  • Purpose: The purpose of this study is to determine the usefulness of arterial embolization on sacral and pelvic giant cell tumor (GCT). Materials and Methods: We retrospectively reviewed the medical records of 9 patients who had undergone serial arterial embolization between December 1996 and May 2008. We analyzed the clinical outcomes and therapeutic responsiveness of arterial embolization on sacral and pelvic GCT. Results: Six of 9 cases showed progression of disease (PD) status, even if 5 cases showed PD status despite of additional treatments including surgery and radiation, implying that serial arterial embolization on sacral and pelvic GCT is not effective. Three of 9 cases showed stable disease (SD) or continuous disease free (CDF) status and we analyzed associated factors with these good responses for embolization by ${\chi}^2$ test. The number of feeding vessels under six (p=0.048) and the number of collateral arterial supply under three (p=0.048) in the first angiogram showed significant relationships with good response for embolization, while remaining tumor staining by contrast after the first embolization and repeated embolization times were not significant. Conclusion: Although serial arterial embolization is not an effective modality on sacral and pelvic giant cell tumors, it may be a pilot modality under narrow indication of tumors with poor vascularity at first angiogram.

Clinical and Pathologic Features of Patients with Rare Ovarian Tumors: Multi-Center Review of 167 Patients by the Anatolian Society of Medical Oncology

  • Bilici, Ahmet;Inanc, Mevlude;Ulas, Arife;Akman, Tulay;Seker, Mesut;Babacan, Nalan Akgul;Inal, Ali;Bal, Oznur;Koral, Lokman;Sevinc, Alper;Tufan, Gulnihal;Elkiran, Emin Tamer;Ustaalioglu, Bala Basak Oven;Yavuzsen, Tugba;Alkis, Necati;Ozkan, Metin;Gumus, Mahmut
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6493-6499
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    • 2013
  • Background: Non-epithelial malignant ovarian tumors and clear cell carcinomas, Brenner tumors, transitional cell tumors, and carcinoid tumors of the ovary are rare ovarian tumors (ROTs). In this study, our aim was to determine the clinicopathological features of ROT patients and prognostic factors associated with survival. Materials and Methods: A total of 167 patients with ROT who underwent initial surgery were retrospectively analyzed. Prognostic factors that may influence the survival of patients were evaluated by univariate and multivariate analyses. Results: Of 167 patients, 75 (44.9%) were diagnosed with germ-cell tumors (GCT) and 68 (40.7%) with sex cord-stromal tumors (SCST); the remaining 24 had other rare ovarian histologies. Significant differences were found between ROT groups with respect to age at diagnosis, tumor localization, initial surgery type, tumor size, tumor grade, and FIGO stage. Three-year progression-free survival (PFS) rates and median PFS intervals for patients with other ROT were worse than those of patients with GCT and SCST (41.8% vs 79.6% vs 77.1% and 30.2 vs 72 vs 150 months, respectively; p=0.01). Moreover, the 3-year overall survival (OS) rates and median OS times for patients with both GCT and SCST were better as compared to patients with other ROT, but these differences were not statistically significant (87.7% vs 88.8% vs 73.9% and 170 vs 122 vs 91 months, respectively; p=0.20). In the univariate analysis, tumor localization (p<0.001), FIGO stage (p<0.001), and tumor grade (p=0.04) were significant prognostic factors for PFS. For OS, the univariate analysis indicated that tumor localization (p=0.01), FIGO stage (p=0.001), and recurrence (p<0.001) were important prognostic indicators. Multivariate analysis showed that FIGO stage for PFS (p=0.001, HR: 0.11) and the presence of recurrence (p=0.02, HR: 0.54) for OS were independent prognostic factors. Conclusions: ROTs should be evaluated separately from epithelial ovarian cancers because of their different biological features and natural history. Due to the rarity of these tumors, determination of relevant prognostic factors as a group may help as a guide for more appropriate adjuvant or recurrent therapies for ROTs.

Design Optimization for High Power Inverters

  • Schroder D.;Kuhn H.
    • Proceedings of the KIPE Conference
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    • 2001.10a
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    • pp.713-717
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    • 2001
  • This paper focuses on a network model for GCTs which can be used to investigate high power circuits with or without using RC-snubbers. The series connection of GCTs is commonly applied in the high power inverter field. Here expensive and space-consuming snubbers are applied, to overcome the problem of an asymmetric distribution of the blocking voltage among the single GCTs. As an alternative to large snubbers, a new active gate drive concept is proposed and investigated by simulation.

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A Combined Clock and Data Recovery Circuit with Adaptive Cancellation of Data-Dependent Jitter

  • Lee, Jin-Hee;Kim, Su-Hwan;Jeong, Deog-Kyoon
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.8 no.3
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    • pp.193-199
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    • 2008
  • A combined clock and data recovery (CDR) circuit with adaptive cancellation of data-dependent jitter (DDJ) is constructed in all-digital architecture which is amenable to deep submicron technology. The DDJ canceller uses an adaptive FIR filter to compen-sate for any unknown channel characteristic. The proposed CDR decreases jitter in the recovered clock since the DDJ canceller significantly cancels out incoming jitter caused by inter-symbol interference.

Reconstruction of Distal Radius Using Ultrahigh Molecular Weight Polyethylene Liner after Excision of Giant Cell Tumor - A Case Report - (원위 요골에 발생한 거대 세포종의 일괄 절제 후 초고분자량 폴리에틸렌 삽입물을 이용한 재건술 - 증례보고 -)

  • Jeon, Dae-Geun;Song, Won-Seok;Oh, Jung-Moon
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.29-33
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    • 2004
  • A giant cell tumor (GCT) of the distal radius is not common. Curettage with bone cementation is considered as a treatment of choice but, in the case of recurrence, marked cortical disruption, or articular invasion, en bloc excision and reconstruction with proximal fibular bone graft is usual procedure. In reconstruction of en bloc resected distal radius which had recurred GCT after conservative operation, we used the ultrahigh molecular weight polyethylene (UHMWPE) liner with intramedullary rod and bone cement, because the contamination was extent in previous operation and recurrence after fibular bone graft was fearful. This article introduce our new surgical procedure.

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Time-Domain Solutions of the VV, HV, VH Problems at the Surface of a Normally Uniaxial Half-Space Dielectric (수직 단축성을 갖는 반공간 유전체 표면에서 VV, HV, VH 문제의 시간영역 해)

  • Lihh Won-Seok;Nam Sang-Wook
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.12 s.103
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    • pp.1246-1254
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    • 2005
  • Theoretical investigation is made on the electromagnetic fields generated by an impulsive point current source, fur the VV, HV, and VH problems at the interface between an isotropic upper half-space medium and a normally uniaxial lower half-space medium. The electric fields of these problems are associated only with the extraordinary-wave components in the Fourier-Laplace domain. Applying the Cagniard-de Hoop method to each problem, the time-domain solutions of the wave fields are obtained. The fields of the VV case can be expressed in explicit(integral-free) forms. The fields of the HV and VH cases are not integral-free, but the major singularities implicit in the integral solutions can be analytically extracted. The interfacial far fields in the frequency domain are determined by the singularities in the time domain.

Granulosa Cell Tumor of Ovary in a Yorkshire terrier Dog (요크셔테리어에서 발생한 난소의 Granulosa cell tumor)

  • Sung, Ju-Heon;Yoo, Jong-Hyun;Kang, Byeong-Tack;Park, Chul;Jung, Dong-In;Park, Jong-Im;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.24 no.1
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    • pp.38-41
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    • 2007
  • A 12-year-old, intact female Yorkshire terrier was presented with progressive abdominal distention. On radiographic and ultrasonographic evaluation, a large mass was detected in right upper abdomen and it had several discrete anechoic follicles and large cysts. The mass was removed by complete ovariohysterectomy and the resected specimen was histopathologically examined. Based on the gross and histopathologic findings, the mass was definitely diagnosed as malignant granulosa cell tumor (GCT). Until now, the dog has been successfully managed more than a year without complications.

Granular Cell Tumor of the Axillary Accessory Breast: A Case Report (액와부 부유방에 발생한 과립 세포 종양: 증례 보고)

  • Youn Joo Jung;Kyung Jin Nam;Ki Seok Choo;Kyeyoung Lee
    • Journal of the Korean Society of Radiology
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    • v.84 no.1
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    • pp.275-279
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    • 2023
  • Granular cell tumors (GCTs) are rare benign soft tissue tumors that can occur throughout the body, particularly the head and neck; only 5%-8% of GCTs occur in the breast. We report a case of a GCT of the axillary accessory breast, which is a rare location of this tumor. A 50-year-old woman had a 2-month history of a palpable mass in the left axilla. Physical examination, as well as mammographic and ultrasonographic findings suggested a breast malignancy. Histopathological examination showed a benign GCT, and wide local excision was performed. The patient has remained disease-free over 2 years postoperatively. Although most GCTs are benign, wide complete resection of the tumor and follow-up are required considering the possibility of recurrence. The radiologist should know the characteristics of GCTs as a differential diagnosis of breast and axillary lesions to prevent unnecessary treatment.

A Rare Case of Concomitant Intramedullary Gangliocytoma at the Cervicomedullary Junction in Patient with Neuroendocrine Tumor of Lung

  • Aydemir, Fatih;Cekinmez, Melih;Kardes, Ozgur;Kayaselcuk, Fazilet
    • Journal of Korean Neurosurgical Society
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    • v.59 no.2
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    • pp.158-160
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    • 2016
  • Ganglion cell tumors (GCT) are divided into two subtypes : gangliocytoma and ganglioglioma. Intramedullary gangliocytomas are extremely rare. A 20-year-old male patient with pain of neck, who also had a previously known neuroendocrine tumor of lung, was operated for mass found in the cervicomedullary junction with a presumptive diagnosis of metastases. Only partial resection could be performed. Pathological diagnosis had been reported as gangliocytoma. Only ten cases of intramedullary gangliocytoma have been reported in the literature. Although association with scoliosis and Von Recklinghausen;s disease were previously reported in the literature, no gangliocytoma case concomitant with endocrine tumor of lung have been published. Pathological study is the most important diagnostic method for gangliocytomas. Surgical excision is the primary treatment, but difficulty in total surgical tumor resection is the most important problem.