Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Granular Cell Tumor of the Axillary Accessory Breast: A Case Report

액와부 부유방에 발생한 과립 세포 종양: 증례 보고

  • Youn Joo Jung (Department of Surgery, Pusan National University Yangsan Hospital) ;
  • Kyung Jin Nam (Department of Radiology, Pusan National University Yangsan Hospital) ;
  • Ki Seok Choo (Department of Radiology, Pusan National University Yangsan Hospital) ;
  • Kyeyoung Lee (Department of Radiology, Pusan National University Yangsan Hospital)
  • 정윤주 (양산부산대학교병원 외과) ;
  • 남경진 (양산부산대학교병원 영상의학과) ;
  • 추기석 (양산부산대학교병원 영상의학과) ;
  • 이계영 (양산부산대학교병원 영상의학과)
  • Received : 2022.09.22
  • Accepted : 2022.12.13
  • Published : 2023.01.01
Download PDF
⟨ Previous Next ⟩

Abstract

Granular cell tumors (GCTs) are rare benign soft tissue tumors that can occur throughout the body, particularly the head and neck; only 5%-8% of GCTs occur in the breast. We report a case of a GCT of the axillary accessory breast, which is a rare location of this tumor. A 50-year-old woman had a 2-month history of a palpable mass in the left axilla. Physical examination, as well as mammographic and ultrasonographic findings suggested a breast malignancy. Histopathological examination showed a benign GCT, and wide local excision was performed. The patient has remained disease-free over 2 years postoperatively. Although most GCTs are benign, wide complete resection of the tumor and follow-up are required considering the possibility of recurrence. The radiologist should know the characteristics of GCTs as a differential diagnosis of breast and axillary lesions to prevent unnecessary treatment.

과립 세포 종양은 신체의 모든 부위에서 발생할 수 있으나, 특히 두경부에서 주로 발생하는 드문 양성 연부 종양이며, 이 중 5%-8%가 유방에서 발생한다. 저자들은 드문 부위인 액와부 부유방에 발생한 과립 세포 종양 1예를 보고하고자 한다. 50세 여자에게 2개월 전부터 좌측 액와부에 만져지는 종괴가 있었다. 이학적 검사, 유방 촬영술 및 초음파 소견에서 유방의 악성 종양을 먼저 생각하였다. 조직 검사에서 양성 과립 세포 종양으로 진단되었으며 이후 광범위 국소 절제술을 시행하였다. 환자는 수술 후 2년의 추적 관찰 기간 동안 재발하지 않았다. 대부분의 과립 세포 종양은 양성이지만, 재발의 가능성 때문에 종양의 광범위한 완전 절제와 추적 관찰이 필요하다. 영상의학과 의사는 불필요한 치료를 막기 위해 유방 및 액와부 병변의 감별 진단으로 과립 세포 종양의 특징에 대해 알고 있어야 한다.

Keywords

Acknowledgement

This study was supported by a 2021 research grant from Pusan National University Yangsan Hospital (2021-84).

References

  1. Pergel A, Yucel AF, Karaca AS, Aydin I, Sahin DA, Demirbag N. A therapeutic and diagnostic dilemma: granular cell tumor of the breast. Case Rep Med 2011;2011:972168 
  2. Gogas J, Markopoulos C, Kouskos E, Gogas H, Mantas D, Antonopoulou Z, et al. Granular cell tumor of the breast: a rare lesion resembling breast cancer. Eur J Gynaecol Oncol 2002;23:333-334 
  3. Yang WT, Edeiken-Monroe B, Sneige N, Fornage BD. Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound 2006;34:153-160 
  4. Adeniran A, Al-Ahmadie H, Mahoney MC, Robinson-Smith TM. Granular cell tumor of the breast: a series of 17 cases and review of the literature. Breast J 2004;10:528-531 
  5. Liu H, Tao M, Ding H, Zhang P. Ultrasonographic manifestations of a rare granular cell tumor of the accessory breast: a case report. Medicine (Baltimore) 2018;97:e9462 
  6. Olivier L, Naraynsingh V, Hassranah D, Cassim C. Abrikossoff tumor clinically mimicking carcinoma in accessory axillary breast tissue. Cureus 2022;14:e21733 
  7. Scaranelo AM, Bukhanov K, Crystal P, Mulligan AM, O'Malley FP. Granular cell tumour of the breast: MRI findings and review of the literature. Br J Radiol 2007;80:970-974 
  8. Abreu N, Filipe J, Andre S, Marques JC. Granular cell tumor of the breast: correlations between imaging and pathology findings. Radiol Bras 2020;53:105-111 
  9. Brown AC, Audisio RA, Regitnig P. Granular cell tumour of the breast. Surg Oncol 2011;20:97-105 
  10. Heinzerling NP, Koehler SM, Szabo S, Wagner AJ. Pediatric granular cell tumor of the breast: a case report and review of the literature. Case Rep Surg 2015;2015:568940