• Title/Summary/Keyword: GBP

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Detection of Mycoplasma Infection in Cultured Cells on the Basis of Molecular Profiling of Host Responses

  • Chung, Tae Su;Kim, Ju Han;Lee, Young-Ju;Park, Woong-Yang
    • Genomics & Informatics
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    • v.3 no.3
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    • pp.63-67
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    • 2005
  • Adaptive responses to diverse microbial pathogens might be limited in relatively few types. Host cell responses to pathogens are believed to be patterned or stereotyped along with species or class. We tried to compose the host response to Mycoplasma in terms of cellular gene expression. Although gene expression profile of two host HeLa and 293 cells were quite different each other, 30 genes were differentially expressed by mycoplasma infection in both of HeLa and 293 cells. Six of them (PR48, MADH4, MKPX, CRK, RBM7, NEK3) were related to cell cycle or proliferation. Another category of genes like IL1 HY1, KLRF1, TNFSF14, GBP1 were host defense to elicit immune responses. With this set of genes, we establish the prediction model for mycoplasma contamination.

Implementation and modeling of wavelength tunable all-optical clok recovery using a semiconductor-fiber ring laser (고리형 반도체-광섬유 레이저를 이용한 파장 가변형 전광 동기 신호 재생 구현과 모델링)

  • 유봉안;김동환;이병호
    • Korean Journal of Optics and Photonics
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    • v.11 no.3
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    • pp.166-170
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    • 2000
  • A wavelength tunable all-optical clock recovery using a semiconductor optical amplifier in a fiber ring cavity is proposed and demonstrated at the wavelength of 1530 nm to 1570 nm. A synchronized optical pulse train is recovered from 10 Gbps and 30 Gbps randomly generated optical pulse streams with injection locking technique. Also, the system responses to the perturbation and the input average power variation are analyzed by a large-signal model based on time-domain travelling wave equation. ation.

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A study on the method of acquiring IO statistical information for each user task of the KISTI-5 supercomputer (슈퍼컴퓨터 5호기 사용자의 작업별 IO 통계정보 획득 방안에 대한 연구)

  • Kwon, Min-Woo;Yoon, JunWeon;Hong, TaeYoung
    • Annual Conference of KIPS
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    • 2021.11a
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    • pp.6-8
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    • 2021
  • 슈퍼컴퓨터 5호기 누리온은 8,437대의 계산노드와 33.88PB 규모의 병렬스토리지가 100Gbps의 Omni-Path(OPA) 인터커넥트로 연결되어 있는 초대형 클러스터 시스템이다. 누리온의 계산자원은 PBS 작업스케줄러를 통해 관리되고 있고 병렬 스토리지는 DDN사의 Exascaler Monitoring System(ESMON)을 통해 influxDB에 read/write IO 통계 데이터를 수집하고 있다. 본 논문에서는 PBS의 과금 데이터와 ESMON influxDB의 IO 통계 데이터를 활용하여 사용자의 작업별 IO 통계 정보를 생성하는 방안에 대하여 소개한다.

Characteristics of an 1.25 Gbps 850 nm Oxide VCSEL Transmitter Operating at Fixed Current over a Wide Temperature Range (넓은 온도 범위에서 고정 구동전류로 동작하는 1.25 Gbps 850 nm 산화형 VCSEL 송신기의 특성)

  • Kim, Tae-Ki;Kim, Tae-Yong;Kim, Sang-Bae;Kim, Sung-Han
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.12
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    • pp.43-53
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    • 2007
  • We have analyzed low current operation characteristics of a VCSEL transmitter operating at fixed Current over wide temperature range. Used 850 nm oxide VCSEL has low temperature dependence of the threshold current and $d^2I_{th}/dT^2$ is approximately $1.346\times10^{-4}mA/^{\circ}C^2$. We fixed on-current so that output power from the chip is 1 mW at $20^{\circ}C$ and investigated the turn-on, turn-off characteristics and eye-diagram of the 850 nm oxide VCSEL transmitter with varying ambient temperature and off-current. We measured rise time, fall time, extinction ratio and timing jitter by changing tile ambient temperature and off-current. With the fixed off-current of around $0.1\sim0.2mA$ lower than the lowest threshold current the transmitter successfully operated at 1.25 Gbps over a wide temperature range from $-20^{\circ}C$ to $80^{\circ}C$.

Design and Implementation of an Alternate System Interconnect based on PCI Express (PCI Express 기반 시스템 인터커넥트의 설계 및 구현)

  • Kim, Young Woo;Ren, Ye;Choi, WonHyuk
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.8
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    • pp.74-85
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    • 2015
  • PCI Express is a well-known and widely used de-facto system bus standard for connecting among a processor and IO devices. PCI Express is originated from old PCI standard, and its most of applications are limited to be used within a PC or server system. But, because of its fast speed, low power consumption, and good protocol efficiency, it is considered as one of a good candidate for an alternate system interconnect for many years. In this paper, we present design, implementation and early evaluation of an alternate system interconnect by utilizing PCI Express. The developed alternate system interconnect using PCI Express (named PCIeLINK) utilizes non-transparent bridging (NTB) technic which generally used in fail-over system in PCI and PCI Express. By using NTB technic, PCI Express device can be extended to outside of a system without electrical and logical problems arising during system boot and enumeration. To build up an alternate system interconnect, we designed and implemented a network interface card having multiple PCI Express ${\times}4$ connections (theoretically 20 Gbps) and tested, The early test results revealed that an ${\times}4$ port in the card showed 8.6 Gbps peak performance for bulk transmission and 5.1 Gbps peak for normal TCP/IP transfer.

Comparison between Myocardial Perfusion and Function in Rest State in Coronary Artery Disease - Dipyridamole $^{99m}Tc-MIBI$ SPECT and Rest Gated Blood Pool Scan - (관상동맥질환에서 휴식기의 심근관류 정도와 휴식기 심기능 변화의 비교 - Dipyridamole 부하 $^{99m}Tc-MIBI$ SPECT와 휴식기 Gated Blood Pool Scan -)

  • Choi, Chang-Woon;Lee, Dong-Soo;Kim, Sang-Eun;Bae, Sang-Kyun;Yang, Hyung-In;Chung, June-Key;Lee, Myoung-Mook;Lee, Myung-Chul;Park, Young-Bae;Seo, Jung-Don;Lee, Young-Woo;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.2
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    • pp.265-273
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    • 1992
  • Rest gated blood pool scan (Rest GBP scan) and dipyridamole $^{99m}Tc-MIBI$ SPECT were Performed in 34 patients with or suspected coronary artery disease. Both studies were performed within $2\sim32$ days (mean 8.1 days). A significant correlation was present between left ventricular ejection fraction (r= -0.7356, p<0.001) and peak ejection rate and peak filling rate in rest GBP scan and perfusion defect in MIBI SPECT. And there were acceptable correlations (0.05$26.2{\pm}10.8%$, severe hypokinesia, akinesia or dyskinesia in 16 regions: $78.2{\pm}23.7$, p<0.001). These data indicate there is a significant coupling between the degree of myocardial perfusion and the myocardial functional change in coronary artery disease.

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Origin and evolution of Korean ginseng revealed by genome sequence

  • Cho, Woohyeon;Shim, Hyeonah;Yang, Tae-Jin
    • Journal of Ginseng Culture
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    • v.3
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    • pp.1-10
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    • 2021
  • Panax ginseng (Ginseng or Korean ginseng) is one of the most important medicinal herbs in the world. We made a high-quality whole genome sequence of P. ginseng using 'Chunpoong' cultivar, which is the first cultivar registered in Korea Seed and Variety Service (KSVS) with relatively similar genotypes and superior phenotypes, representing approximately 3 Gbp and 60,000 genes. Genome sequence analyses of P. ginseng and related speciesrevealed the origin of Korean ginseng and the ecological adaptation of 18 Panax species around the world. Korean ginseng and American ginseng (P. quinquefolius) are tetraploid species having 24 chromosome pairs, while the other 16 species are diploid species with 12 chromosome pairs. Panax and Aralia are the closest genera belonging to the Araliaceae family that diverged approximately 8 million years ago (MYA). All Panax species evolved as shade plants adapting to cool climates and low light conditions under the canopy of deep forests from Southeast Asia such as Vietnam to Northeast Asia such as Russia approximately 6 MYA. However, through recurrent ice ages and global warming, most diploid Panax species disappeared due to the freezing winter, while tetraploid P. ginseng may have appeared by allotetraploidization, which contributed to the adaptation to cold temperaturesin Northeast Asian countries including the Korea peninsula approximately 2 MYA. American ginseng evolved by the adaptation of P. ginseng in Northeast America after the intercontinental migration 1 MYA. Meanwhile, most of diploid Panax species survived in high-altitude mountains over 1,600 meters in Southeast Asia because they could not endure the hot temperature and freezing cold. The genome sequence provides good basisto unveil the origin and evolution of ginseng and also supports practical gene chips which is useful for breeding and the ginseng industry.

Design of a High-Speed LVDS I/O Interface Using Telescopic Amplifier (Telescopic 증폭기를 이용한 고속 LVDS I/O 인터페이스 설계)

  • Yoo, Kwan-Woo;Kim, Jeong-Beom
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.6 s.360
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    • pp.89-93
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    • 2007
  • This paper presents the design and the implementation of input/output (I/O) interface circuits for 2.5 Gbps operation in a 3.3V 0.35um CMOS technology. Due to the differential transmission technique and low voltage swing, LVDS(low-voltage differential signaling) has been widely used for high speed transmission with low power consumption. This interface circuit is fully compatible with the LVDS standard. The LVDS proposed in this paper utilizes a telescopic amplifier. This circuit is operated up to 2.3 Gbps. The circuit has a power consumption of 25. 5mW. This circuit is designed with Samsung $0.35{\mu}m$ CMOS process. The validity and effectiveness are verified through the HSPICE simulation.

A CMOS Optical Receiver Design for Optical Printed Circuit Board (광PCB용 CMOS 광수신기 설계)

  • Kim Young;Kang Jin-Ku
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.43 no.7 s.349
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    • pp.13-19
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    • 2006
  • A 5Gb/s cross coupled transimpedance amplifier (TIA) & limiting amp(LA), regulated cascode(RGC) is realized in a 0.18$\mu$m CMOS technology for optical printed circuit board applications. The optical receiver demonstrates $92.8db{\Omega}$ transimpedance and limiting amplifier gain, 5Gb/s bandwidth for 0.5pF photodiode capacitance, and 9.74mW power dissipation from 1.8V, 2.4V supply. Input stage impedance is $50{\Omega}$. The circuit was implemented on an optical PCB, and the 5Gb/s data output signal was measured with a good data eye opening.

Scheme for transmitting Data and TDM based on E-PON (E-PON 기반 데이터 및 TDM 전달을 위한 방안)

  • Jin, Geol;Park, Chun-Kwan
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2007.04a
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    • pp.465-468
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    • 2007
  • This paper addresses the scheme for transmitting Data and TDM signals based on E-PON. E-PON technology, that combines low-cost Ethernet technology and optical fiber infra-structure, has been appeared as a solution of next generation access network. The transmission speed of E-PON is 1Gbps and symmetric in both direction, such as downstream and upstream. Therefore, it is possible to save the cost through sample network architecture, efficient operation, and low maintenance cost of optical IP Ethernet network. By adding TBMoIP(Time Division Multiplexing over Internet Protocol) module to this E-PON system, and implementing QoS(Quality of Service) control function, this system can provide data and TDM service efficiently.

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