• Title/Summary/Keyword: G2-phase

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Effects of Nonnutritive Sucking on Behavioral State in Preform Infants (비영양 흡철의 미숙아 행동상태에 대한 효과)

  • Shin Hee Sun
    • Child Health Nursing Research
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    • v.4 no.2
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    • pp.305-313
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    • 1998
  • The purpose of study was to examine the effect of nonnutritive sucking(NNS) on behavioral state in preform infants. Fourteen infants (gestational age 28-35 weeks, M=31.86 ; birth weights 1095-2275g, M=1694g) admitted to NICU, serving as their controls were randomly administered 5 min of nonnutritive sucking and a control condition. Behavioral state was measured using the Anderson Behavioral State Scale(ABSS). Heart rates were obtained for each infant before and during NNS and bottle feeding. Data collecction was done by 3 experienced nurses in NICU 2 times a day for conseculive 4 days for each subject. Interrater reliability were .80-.90. The findings were as follows : 1. Preform infants averaged active restless states 58.93% in the prointervention phase and 27.32% in the NNS phase. Inactive awake states were 3.57% in the preintervention phase and 34.64% in the NNS phase. 2. There were significantly more positive changes to inactive awake states for the NNS intervention, Z=-2.35, p=.01. 3. There was no statistically significant difference in heart rate change between NNS intervention and control condition, z=-1.15, p=.24. 4. The rates of feeding success determined by finishing prescribed amount of milk by bottle feeding within 15 minutes were 83.94% in NNS intervention and 89.29% in control condition. The findings from this study confirmed that NNS is effective for behavioral state modulation and inducing optimal state for feeding in preform infant. The NNS intervention in nursing practice may help the transition of preform infants for nipple feeding.

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Antitumor and Immunological Effects of Bovine Thymic Extract (소 흉선 추출물의 암세포 증식 및 림프구에 미치는 영향)

  • Chung, Yong Za;Hong, Gi Tae;Jung, Hyun Ok
    • Korean Journal of Clinical Pharmacy
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    • v.2 no.1
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    • pp.11-22
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    • 1992
  • Thymic extract showed antitumor effect to sarcoma mice with higher dose$(200{\mu}g/mouse/day$ i.p., 4weeks) but not with low dose$(5{\mu}g/mouse/day$ i.p., 6 weeks). Direct cytotoxicities were exhibited against sarcoma 180, L1210 and MOLT-4 by MTT assay. The spleen weight of mice were increased but the number of circulating lymphocytes were not increased after long-term(2 weeks) administration of thymic extract. Evaluating the mitogenesis by MTT assay. $\%$ absorbance of human lymphocytes was not increased by thymic extract. Cell cycle statistics of S phase and $G_2/M$ phase was not increased in the presence of that by PI staining. The formation of rosette was induced, irrespectively of exposure time short-term(l hour) and long-term(2 weeks). The population of mouse blood T-cell to bind Lyt2-antimonoclonal antibody and to $L_2T_4$ were increased after administration of thymic extract$(2-200{\mu}g/mouse/day)$. From the above results, it is suggested that thymic extract exerts antitumor activity by stimulating T cells to differeniate in vivo but not in vitro.

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A Gap Phase-Specific Inhibitor of the Mammalian Cell Cycle from Streptomyces sp. ZF10 (Streptomyces sp. ZF-10이 생산하는 세포주기 저해제)

  • ;;Hiroyuki Osada
    • Microbiology and Biotechnology Letters
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    • v.22 no.5
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    • pp.495-498
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    • 1994
  • Genistein, a inhibitor of the progression of G$_{1}$ and G$_{2}$ phase of the mammalian cell cycle, was discovered through a unique screening system, in which effects of microbial metabolites on the cycle progression of the cultured mouse mammalian carcinoma cell were monitored by flow cytometry. The inhibitor was extracted from the fermentation broth of Streptomyces sp. ZF10 with ethyl acetate, and purified by silica gel column chromatography and HPLC.

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pH Effect at Thermophilic Solubilization Pretreatment of Food Waste in Two Phase Anaerobic Digestion (2상 혐기성 소화에서 음식물쓰레기의 고온 가용화 전처리 pH 영향)

  • Lee, Won-Soo;Kang, Young-Jun;Seo, Gyu-Tae
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.8
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    • pp.452-458
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    • 2016
  • The study on pH control at the themophilic solubilization (pretreatment process) was investigated in order to improve the methane gas production of two phase anaerobic digestion of food waste. From a batch experiment, it was observed that the solubilization efficiency was increased from 26.2% to 47.1% and 55.6% by the pH increament from $4.20{\pm}0.40$ (without pH control) to $7.00{\pm}0.50$, and $12.00{\pm}0.50$, respectively. However there was immaterial increase (8.5%) in solubilization efficiency when the pH was increased from $7.00{\pm}0.50$ to $12.00{\pm}0.50$. The two phase anaerobic digestion system was operated for laboratory scale experiment under the solubilization condition of pH $4.20{\pm}0.40$ (Run1) and $7.00{\pm}0.50$ (Run2). Higher soluble chemical oxygen demand (SCOD) and total volatile fatty acid (TVFA) concentration were observed in Run2 throughout the system resulted by the solubilization effect at the pH $7.00{\pm}0.50$. The TVFA concentration in acidogenic reactor was 18.4 g/L which was 1.8 times higher than the result of Run1. Consequently the methane gas production was enhanced to 0.333 L/g VS in the methanogenic reactor, which is 18% higher than the result (0.282 L/g VS) of Run1.

Volatile Substances and Physicochemical Characteristics of Pyroligneous Liquor (목초액의 휘발성 성분과 이화학적 특성)

  • Kim Jong-Soo;Park Seung-Woo;Choi Jung-Hwan;Lee Eun-Young;Lee Sang-Han;Chung Shin-Kyo
    • Food Science and Preservation
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    • v.12 no.6
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    • pp.656-661
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    • 2005
  • To develop food additives from pyroligneous liquor, we first examined the physicochemical characteristics of volatile substances. The pH, gravity, acidity, solution tar, and scorched remains in the pyroligneous liquor were 2.50, 1.020, $0.8\%$ $2.31\%$ and $0.008\%$ respectively. The main compounds of pyroligneous liquor were 2,6-dimethoxyphenol (syringol), 2-hydroxy-2-cyclopenten-l-one, 1,2-benzenediol (catechol), phenol, 2 (5H)-furanone, 2-methoxyphenol (guaiacol), 5-hydroxymethyl-2 furancarboxaldehyde were found in organic phase, whereas catechol, 1,4 : 3,6-dianhydro-${\alpha}d$-glucopyranose, cyclopropyl carbinol, 5-hydroxymethyl-2 furancarboxaldehyde in aqueous phase.

Growth and Cadmium Removal in Recombinant Saccharomyces cerevisiae Harboring A Metallothionein Gene (Metallothionein 유전자가 도입된 재조합 Saccharomyces cerevisiae의 생육과 카드뮴 제거)

  • 김대옥;박성식서진호
    • KSBB Journal
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    • v.11 no.5
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    • pp.543-549
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    • 1996
  • Recombinant Saccharomyces cerevisiae BZ-pJ containing the gene coding for metallothionein, a metalbinding protein was grown in the medium with high cadmium concentrations to study the characteristics of growth and cadmium uptake. High concentrations of cadmium reduced cell growth and final cell density and increased the lag phase periods of the recombinant yeast. Addition of 10 mg $Cd^{2+}$/L to the growth medium remarkably decreased a lag period and enhanced the specific cadmium uptake to 52.6 mg $Cd^{2+}$/g dry cell. The effect of copper addition was further investigated in the medium of 680 mg Cd2+/L. An increase in copper concentration from 11.0 to 33.3 mg/L enhanced the specific cadmium uptake from 17.0 to 42.0 mg Cd2+/g dry cell.

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Feasibility of Fibrous Solid Phase Extraction to Alkylphenols Analysis (섬유상 고상 추출물질을 이용한 알킬페놀 화합물 분석 가능성)

  • Jung, Yong Jun
    • Journal of Korean Society on Water Environment
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    • v.27 no.3
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    • pp.329-333
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    • 2011
  • p-phenylene-2,5-benzobisoxazole (PBO; Zylon$(R)$) fibers as an adsorbent were employed for solid phase extraction of aqueous alkylphenols. The removal ratios for 10 kinds of alkylphenols at initial concentration of $100{\mu}gL^{-1}$ were in the range of 16.8-96.3% and the removals increased with the increase of the phase ratio (fiber weight/solution volume). The plots of the logarithm of partition coefficient (log K) were correlated with the logarithm of the n-octanol/water partition coefficient (log P). The adsorbed alkylphenols were completely desorbed with the mixture of acetonitrile and dichloromethane.

Current Ripple Reduction Method of 3-phase Interleaved Bidirectional DC-DC Converter with the Consideration of Input and Output Voltage Variation (입·출력 전압 변동을 고려한 3상 인터리브드 양방향 DC-DC컨버터의 전류리플 저감 기법)

  • Sun, Daun;Jung, Jae-Hun;Nho, Eui-Cheol;Joung, Gyu-Bum
    • The Transactions of the Korean Institute of Power Electronics
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    • v.21 no.5
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    • pp.427-433
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    • 2016
  • This paper proposes a new method for the current ripple reduction of a three-phase interleaved bidirectional DC-DC converter. Usually, the three-phase interleaved bidirectional DC-DC converter is used for battery charging and discharging to reduce battery current ripple. In V2G application, a PWM AC-DC converter is used to connect the AC power grid and three-phase interleaved bidirectional DC-DC converter for battery charging and discharging. The magnitude of DC link voltage affects the battery current ripple magnitude. Therefore, the magnitude of the battery ripple current is analyzed with variations of battery and DC link voltages. The ripple current magnitude is found to be minimized by controlling the DC link voltage. Simulation and experimental results show the usefulness of the proposed method.

STUDY ON ATMOSPHERIC BEHAVIOR OF POLYCYCLIC AROMATIC HYDROCARBONS IN URBAN AREA, JEONJU

  • Kim, Hyoung-Seop;Kim, Jong-Guk;Kim, Kyoung-Soo
    • Environmental Engineering Research
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    • v.12 no.3
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    • pp.118-127
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    • 2007
  • Between June and November 2002, the atmospheric concentrations and dry deposition fluxes of polycyclic aromatic hydrocarbons (PAHs) in Chonju were measured four times each over five days. The total concentration of PAHs in ambient air was $84\;ng/m^3$, with about 90% existing in the vapor phase. Plots of log ($K_p$) vs. log (${P_L}^0$) indicated that PAHs partitioning was not in equilibrium and the particulate characteristics did not change with seasonal variations. The PAHs fluxes to a water surface sampler (WSS) and a dry deposition plate (DDP) were about 14.15 and $1.92\;{\mu}g/m^2/d$, respectively. The flux of the gaseous phase, acquired by subtracting the DDP from the WSS results, was about $12.23\;{\mu}g/m^2/d$. A considerable correlation was shown between the atmospheric concentrations and deposition fluxes in the gaseous phase, but not in the particulate phase, as the fluxes of the particulate phase were dependent on the physical velocity differences of the particulates based on the particle diameter.

Fugitive Emission Characteristics of HFC-134a from Reefer Container (냉동컨테이너에서의 HFC-134a 탈루배출 특성에 대한 연구)

  • Kim, Eui-Kun;Kim, Seungdo;Lee, Young Phyo;Byun, Seokho;Kim, Hyerim
    • Journal of Korean Society for Atmospheric Environment
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    • v.30 no.2
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    • pp.110-118
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    • 2014
  • This paper addresses the fugitive emission factors of Reefer Container at use-phase and disposal-phase. The residual quantities and operation time of thirty nine Container were weighed, using a commercial recover of refrigerants to determine the emission factors at the use-phase. The emission factor at the disposal-phase, refrigerant is accomplished has not recycled, the residual rate was assumed that the emission factor. The average residual rate of thirty nine Container is determined to be $70.8{\pm}4.0%$. The emission factor at the use-phase is estimated to be $4.9{\pm}0.9%/yr$ in the case of using average age of 8.1 years and the average residual rate determined here. We estimate 162.7 g/yr for the average emission quantity of refrigerant per operating Container, while 2038.1 g for that per waste Container. Since the chemical compositions of refrigerant of waste Container were the same as those of new refrigerant, it is expected that the refrigerant recovered from waste Container can be reused for refrigerant.