• Journal of Korean Neurosurgical Society
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• v.42 no.2
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• pp.145-148
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• 2007

Klippel-Feil Syndrome (KFS) is a complex congenital syndrome of osseous and visceral anomalies. It is mainly associated with multi-level cervical spine fusion with hypermobile normal segments. Therefore, a patient with KFS can be at risk of severe neurological symptoms even after a minor trauma. We report a patient with type III KFS who developed a hemiparesis after a minor trauma and was successfully managed with operation.

• BMB Reports
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• v.43 no.6
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• pp.389-399
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• 2010

Fertilization is a complex process comprised of numerous steps. During fertilization, two highly specialized and differentiated cells (sperm and egg) fuse and subsequently trigger the development of an embryo from a quiescent, arrested oocyte. Molecular interactions between the sperm and egg are necessary for regulating the developmental potential of an oocyte, and precise coordination and regulation of gene expression and protein function are critical for proper embryonic development. The nematode Caenorhabditis elegans has emerged as a valuable model system for identifying genes involved in fertilization and the oocyte-to-embryo transition as well as for understanding the molecular mechanisms that govern these processes. In this review, we will address current knowledge of the molecular underpinnings of gamete interactions during fertilization and the oocyte-to-embryo transition in C. elegans. We will also compare our knowledge of these processes in C. elegans to what is known about similar processes in mammalian, specifically mouse, model systems.

• 한국생물공학회:학술대회논문집
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• 2002.04a
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• pp.510-513
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• 2002

Iron is an essential nutrient for most organisms, which supplied to them in a protein-iron complex known as ferritin. Ferritins are multimeric proteins those are consisted of spherical shell of 24 subunits defining a cavity of about 8nm in diameter. Soluble form of ferritin was separated from disrupted cells, followed by silica powder adsorption. Ferritin was recovered from silica-poweder by distiiled water, which was applied to DEAE anion exchage chromatography. Collected fractions from the DEAE column were assayed to gain the amount and the purity of ferritin by using GF-HPLC.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.15-15
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• 2000

In the past couple of years, there has been increasing interest in the fusion of neural networks and fuzzy logic. Most of the existing fused models have been proposed to implement different types of fuzzy reasoning mechanisms and inevitably they suffer from the dimensionality problem when dealing with complex real-world problem. To overcome the problem, we propose the self-organizing networks with activation nodes based on fuzzy inference and polynomial function. The proposed model consists of two parts, one is fuzzy nodes which each node is operated as a small fuzzy system with fuzzy implication rules, and its fuzzy system operates with Gaussian or triangular MF in Premise part and constant or regression polynomials in consequence part. the other is polynomial nodes which several types of high-order polynomials such as linear, quadratic, and cubic form are used and are connected as various kinds of multi-variable inputs. To demonstrate the effectiveness of the proposed method, time series data for gas furnace process has been applied.

• Proceedings of the KIEE Conference
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• 1998.07b
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• pp.566-568
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• 1998

In this paper, we suggest a optimal design method of Fuzzy-Neural Networks model for complex and nonlinear systems. FNNs have the stucture of fusion of both fuzzy inference with linguistic variables and Neural Networks. The network structure uses the simpified inference as fuzzy inference system and the BP algorithm as learning procedure. And we use a clustering algorithm to find initial parameters of membership function. The parameters such as membership functions, learning rates and momentum coefficients are easily adjusted using the genetic algorithms. Also, the performance index with weighted value is introduced to achieve a meaningful balance between approximation and generalization abilities of the model. To evaluate the performance index, we use the time series data for gas furnace and the sewage treatment process.

• Molecules and Cells
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• v.43 no.6
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• pp.501-508
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• 2020

In eukaryotes, membraneous cellular compartmentation essentially requires vesicle trafficking for communications among distinct organelles. A donor organelle-generated vesicle releases its cargo into a target compartment by fusing two distinct vesicle and target membranes. Vesicle fusion, the final step of vesicle trafficking, is driven intrinsically by complex formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). Although SNAREs are well-conserved across eukaryotes, genomic studies revealed that plants have dramatically increased the number of SNARE genes than other eukaryotes. This increase is attributed to the sessile nature of plants, likely for more sensitive and harmonized responses to environmental stresses. In this review, we therefore try to summarize and discuss the current understanding of plant SNAREs function in responses to biotic and abiotic stresses.

• Journal of the Korean Institute of Intelligent Systems
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• v.19 no.1
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• pp.108-114
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• 2009

In this paper, we presents a behavior planning for humanoid robots using behavior primitive in 3 dimensional workspace. Also, we define behavior primitives that humanoid robot accomplishes various tasks effectively. Humanoid robot obtains information of the outside environment and its inner information from various sensors in complex workspace with various obstacles. We verify our approach on a developed small humanoid robot using embedded vision and sensor system in a experimental environment. The experimental results show that the humanoid robot performs its tasks fast and effectively.

• BMB Reports
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• v.41 no.12
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• pp.827-832
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• 2008

Many age-dependent neurodegenerative diseases are associated with the accumulation of abnormally folded proteins within neurons. One of the major proteolytic pathways in the cell is the autophagy pathway, which targets cytoplasmic contents and organelles to the lysosomes for bulk degradation under various physiological and stressful conditions. Although the importance of autophagy in cellular physiology is well appreciated, its precise roles in neurodegeneration remain largely unclear. Recent studies indicate that components of the endosomal sorting complex required for transport (ESCRT) are important in the autophagy pathway. Reduced activity of some ESCRT subunits leads to the accumulation of autophagosomes and failure to clear intracellular protein aggregates. Interestingly, rare mutations in CHMP2B, an ESCRT-III subunit, are associated with frontotemporal dementia linked to chromosome 3 (FTD3). Mutant CHMP2B proteins seem to disrupt the fusion of autophagosomes and lysosomes in cell culture models. These findings suggest a potential mechanism for the pathogenesis of FTD3 and possibly other neurodegenerative diseases as well.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.34S no.3
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• pp.33-45
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• 1997

In this paper, we propsoe a new method of th ecommunication system for cooperative behaviors and works in collective autonomous mobile robots. A communication function among the collective robots is essential to intelligent cooperative works. In genral, global communication is effective for small number of robots. However when the number of robot goes on increasing, this becomes difficult to be realized because of limited communication capacity and increasing amount of information to handle. And also the problems such as communciation interfeence and improper message transmission occur. So we propose local communication system based on infrared sensor to realize the cooperative behavior among robots as the solution of above problem. It is possible to prevent overflow of information and exchange of complex information by fusion sign board model which transmits the information to unspecified robots and message passing model which communicate a specific robot. And we formularize optimal communication range by analysis of information propagation mechanism from the proposed comunication system. At last we verify the effectiveness of the proposed communication system from example of cooperative works.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.765-768
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• 2011

At present, the smart mobile device has been big recognition in general due to fusion, mobility and convenience. On the one hand Industy also needs smart mobile device because more and complex data processing. Hereupon this thesis will study reflected industry needs smart mobile pad's design structure, and applicable area to use this device.