• Title/Summary/Keyword: Fusion-Complex

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Identification and Functional Analysis of SEDL-binding and Homologue Proteins by Immobilized GST Fusion and Motif Based Methods

  • Hong, Ji-Man;Jeong, Mi-Suk;Kim, Jae-Ho;Kim, Boog-il;Holbrook, Stephen R.;Jang, Se-Bok
    • Bulletin of the Korean Chemical Society
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    • v.29 no.2
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    • pp.381-388
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    • 2008
  • An X-linked skeletal disorder, SEDT (spondyloepiphyseal dysplasia tarda) is a genetic disease characterized by a disproportionately short trunk and short stature caused by mutations in the SEDL gene. This gene is evolutionarily conserved from yeast to human. The yeast SEDL protein ortholog, Trs20p, has been isolated as a member of a large multi-protein complex called the transport protein particle (TRAPP), which is involved in endoplasmic reticulum (ER)-to-Golgi transport. The interaction between SEDL and partner proteins is important in order to understand the molecular mechanism of SEDL functions. We isolated several SEDL-binding proteins derived from rat cells by an immobilized GST-fusion method. Furthermore, the SEDL-homologue proteins were identified using motif based methods. Common motifs between SEDL-binding proteins and SEDL-homologue proteins were classified into seven types and 78 common motifs were revealed. Sequence similarities were contracted to seven types using phylogenetic trees. In general, types I-III and VI were classified as having the function of acetyl-CoA carboxylase, glycogen phosphorylase, isocitrate dehydrogenase, and enolase, respectively, and type IV was found to be functionally related to the GST protein. Types V and VII were found to contribute to TRAPP vesicle trafficking.

Design of an observer-based decentralized fuzzy controller for discrete-time interconnected fuzzy systems (얼굴영상과 예측한 열 적외선 텍스처의 융합에 의한 얼굴 인식)

  • Kong, Seong G.
    • Journal of the Korean Institute of Intelligent Systems
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    • v.25 no.5
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    • pp.437-443
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    • 2015
  • This paper presents face recognition based on the fusion of visible image and thermal infrared (IR) texture estimated from the face image in the visible spectrum. The proposed face recognition scheme uses a multi- layer neural network to estimate thermal texture from visible imagery. In the training process, a set of visible and thermal IR image pairs are used to determine the parameters of the neural network to learn a complex mapping from a visible image to its thermal texture in the low-dimensional feature space. The trained neural network estimates the principal components of the thermal texture corresponding to the input visible image. Extensive experiments on face recognition were performed using two popular face recognition algorithms, Eigenfaces and Fisherfaces for NIST/Equinox database for benchmarking. The fusion of visible image and thermal IR texture demonstrated improved face recognition accuracies over conventional face recognition in terms of receiver operating characteristics (ROC) as well as first matching performances.

Automatic Film Restoration Using Distributed Genetic Algorithm (분산 유전자 알고리즘을 이용한 자동 필름 복원)

  • Kim, Byung-Geun;Kim, Kyung-Tai;Kim, Eun-Yi
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.46 no.2
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    • pp.1-9
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    • 2009
  • In recent years, a film restoration has gained increasing attention by many researchers, to support multimedia service of high quality. In general, an old film is degraded by dust, scratch, flick, and so on. Among these, the common factors are scratch and blotch, so that many researchers have been investigated to restore these degradations. However, the methods in literature have one major limitation: A method is working well in dealing with scratches, however it is poorly working in processing the blotches. The goal of this work is to develop a robust technique to restore images degraded by both scratches and blotches. For this, we use MRF-MAP (Markov random field - maximum a posteriori) framework, so that the restoration problem is considered as the minimization problem of the posteriori energy function. As the minimization is one of complex combinatorial problem, we use distributed genetic algorithms (DGAs) that effectively deal with combinatorial problems. To asses the validity of the proposed method, it was tested on natural old films and artificially degraded films, and the results were compared with other methods. Then, the results show that the proposed method is superior to other methods.

Development of Oriental-Western Fusion Patient Monitor by Using the Clip-type Pulsimeter Equipped with a Hall Sensor, the Electrocardiograph, and the Photoplethysmograph (홀센서 집게형 맥진기와 심전도-용적맥파계를 이용한 한양방 융합용 환자감시장치 개발연구)

  • Lee, Dae-Hui;Hong, Yu-Sik;Lee, Sang-Suk
    • Journal of the Korean Magnetics Society
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    • v.23 no.4
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    • pp.135-143
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    • 2013
  • The clip-type pulsimeter equipped with a Hall sensor has a permanent magnet attached in the "Chwan" position to the center of a radial artery. The clip-type pulsimeter is composed of a hardware system measuring voltage signals. These electrical bio-signals display pulse rate, non-invasive blood pressure, respiratory rate, pulse wave velocity (PWV), and spatial pulse wave velocity (SPWV) simultaneously measured by using the radial artery pulsimeter, the electrocardiograph (ECG), and the photoplethysmograph (PPG). The findings of this research may be useful for developing a oriental-western biomedical signal storage device, that is, the new and fusion patient monitor, for a U-health-care system.

Robust Data, Event, and Privacy Services in Real-Time Embedded Sensor Network Systems (실시간 임베디드 센서 네트워크 시스템에서 강건한 데이터, 이벤트 및 프라이버시 서비스 기술)

  • Jung, Kang-Soo;Kapitanova, Krasimira;Son, Sang-H.;Park, Seog
    • Journal of KIISE:Databases
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    • v.37 no.6
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    • pp.324-332
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    • 2010
  • The majority of event detection in real-time embedded sensor network systems is based on data fusion that uses noisy sensor data collected from complicated real-world environments. Current research has produced several excellent low-level mechanisms to collect sensor data and perform aggregation. However, solutions that enable these systems to provide real-time data processing using readings from heterogeneous sensors and subsequently detect complex events of interest in real-time fashion need further research. We are developing real-time event detection approaches which allow light-weight data fusion and do not require significant computing resources. Underlying the event detection framework is a collection of real-time monitoring and fusion mechanisms that are invoked upon the arrival of sensor data. The combination of these mechanisms and the framework has the potential to significantly improve the timeliness and reduce the resource requirements of embedded sensor networks. In addition to that, we discuss about a privacy that is foundation technique for trusted embedded sensor network system and explain anonymization technique to ensure privacy.

Characterization and Mechanical Properties of Stainless Steel 316L Fabricated Using Additive Manufacturing Processes (적층식 제조 공정을 활용한 스테인레스 316L 제작기술의 특징과 기계적 속성)

  • Choi, Cheol;Jung, Mihee
    • KEPCO Journal on Electric Power and Energy
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    • v.7 no.1
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    • pp.129-135
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    • 2021
  • Recently, additive manufacturing (AM) technology such as powder bed fusion (PBF) and directed energy deposition (DED) are actively attempted as consumers' needs for parts with complex shapes and expensive materials. In the present work, the effect of processing parameters on the mechanical properties of 316L stainless steel coupons fabricated by PBF and DED AM technology was investigated. Three major mechanical tests, including tension, impact, and fatigue, were performed on coupons extracted from the standard components at angles of 0, 45, 90 degrees for the build layers, and compared with those of investment casting and commercial wrought products. Austenitic 316L stainless steel additively manufactured have been well known to be generally stronger but highly vulnerable to impact and lack in elongation compared to casting and wrought materials. The process-induced pore density has been proved the most critical factor in determining the mechanical properties of AM-built metal parts. Therefore, it was strongly recommended to reduce those lack of fusion defects as much as possible by carefully control the energy density of the laser. For example, under the high energy density conditions, PBF-built parts showed 46% higher tensile strength but more than 75% lower impact strength than the wrought products. However, by optimizing the energy density of the laser of the metal AM system, it has been confirmed that it is possible to manufacture metal parts that can satisfy both strength and ductility, and thus it is expected to be actively applied in the field of electric power section soon.

Constructing a digital twin for estimating the response and load of a piping system subjected to seismic and arbitrary loads

  • Dongchang Kim;Gungyu Kim;Shinyong Kwag;Seunghyun Eem
    • Smart Structures and Systems
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    • v.31 no.3
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    • pp.275-281
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    • 2023
  • In recent years, technological developments have rapidly increased the number of complex structures and equipment in the industrial. Accordingly, the prognostics and health monitoring (PHM) technology has become significant. The safety assessment of industrial sites requires data obtained by installing a number of sensors in the structure. Therefore, digital twin technology, which forms the core of the Fourth Industrial Revolution, is attracting attention in the safety field. The research on digital twin technology of structures subjected to seismic loads has been conducted recently. Hence, this study proposes a digital twin system that estimates the responses and arbitrary load in real time by utilizing the minimum sensor to a pipe that receives a seismic and arbitrary load. To construct the digital twin system, a finite-element model was created considering the dynamic characteristics of the pipe system, and then updating the finite-element model. In addition, the calculation speed was improved using a finite-element model that applied the reduced-order modeling (ROM) technology to achieve real-time performance. The constructed digital twin system successfully and rapidly estimated the load and the point where the sensor was not attached. The accuracy of the constructed digital twin system was verified by comparing the response of the digital twin model with that derived by using the load estimated from the digital twin model as input in the finite-element model.

The Estimation of Hand Pose Based on Mean-Shift Tracking Using the Fusion of Color and Depth Information for Marker-less Augmented Reality (비마커 증강현실을 위한 색상 및 깊이 정보를 융합한 Mean-Shift 추적 기반 손 자세의 추정)

  • Lee, Sun-Hyoung;Hahn, Hern-Soo;Han, Young-Joon
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.7
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    • pp.155-166
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    • 2012
  • This paper proposes a new method of estimating the hand pose through the Mean-Shift tracking algorithm using the fusion of color and depth information for marker-less augmented reality. On marker-less augmented reality, the most of previous studies detect the hand region using the skin color from simple experimental background. Because finger features should be detected on the hand, the hand pose that can be measured from cameras is restricted considerably. However, the proposed method can easily detect the hand pose from complex background through the new Mean-Shift tracking method using the fusion of the color and depth information from 3D sensor. The proposed method of estimating the hand pose uses the gravity point and two random points on the hand without largely constraints. The proposed Mean-Shift tracking method has about 50 pixels error less than general tracking method just using color value. The augmented reality experiment of the proposed method shows results of its performance being as good as marker based one on the complex background.

Analysis on Complex Disaster Information Contents for Building Disaster Map of Coastal Cities (연안도시 재해지도 작성을 위한 복합재해정보 콘텐츠 분석)

  • KIM, Jung-Ok;KIM, Ji-Young;LEE, Won-Hee
    • Journal of the Korean Association of Geographic Information Studies
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    • v.19 no.3
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    • pp.43-60
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    • 2016
  • Coastal cities need disaster planning that accounts for the complex causes of environmental disasters such as high tides or tsunamis generated by typhoons, and of river or lowland flooding caused by heavy rains, etc. The elements of the disaster map were initially defined using a Geographic Information System (GIS) to allow for efficient information management. Complex disaster information elements were thus established in this study to create a disaster map of coastal cities. The range of information required for coastal cities includes the type of disaster, evacuation methods, available sheltering facilities, and learning content. These informational elements are intended to build on spatial information based on data available from the Ministry of Public Safety and Security as well as local governments.

A Study of Improve Space for Culture Convergence of Local intangible cultural heritage teaching hall (지역 전수교육관의 문화융합을 위한 공간 개선 연구)

  • Lee, Sang-Hee;Jeon, Chil-Soo
    • Journal of the Korea Convergence Society
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    • v.8 no.11
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    • pp.299-306
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    • 2017
  • In this paper, the development of differentiated programs for visitors as well as those for teaching, ways on how to make these halls a culture complex that can support diverse cultural activities for citizens, and strategies to increase their utilization for the public as an facility open to the community, given the trend that intangible cultural heritage teaching halls are getting bigger and complex. The intangible cultural heritage teaching halls of it is need to make improvements to the facility for their activation. Therefore In this paper as a collected information on their establishment and administration to find ways for their activation from a user perspective by visiting three intangible cultural heritage teaching halls except Seoul and large cities of metropolitan areas. We expect that findings from the study will provide a basis to set directions to make intangible cultural heritage teaching halls a culture complex facility.