• Proceedings of the Korean Biophysical Society Conference
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• 1999.06a
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• pp.41-41
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• 1999

The native forms of some proteins such as inhibitory serpins (serine protease inhibitors) and viral membrane fusion proteins are metastable, which is critical to their functions. To understand the mechanism of how native metastability regulates the inhibitory function of serpins, we characterized stabilizing mutations of $\alpha$$_1$-antitrypsin, a prototype serpin, in which Gly 117 was replaced by a series of larger hydrophobic residues.(omitted)

• Journal of Korean Society of Transportation
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• v.17 no.3
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• pp.97-116
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• 1999

The growing demand for the real time traffic information is bringing about the category and number of traffic collection mechanism in the era of ITS. There are, however, two problems in making data into information using various traffic data. First, the information making process of making data into the representative information, for each traffic collection mechanism, for the specified analysis periods is required. Second, the integration process of fusing each representative information into "the information" for each link out of each source is also required. That is, both data reduction and/or data to information process and information fusion are required. This article is focusing on the development of information fusing algorithm based on voting technique, fuzzy regression, and, Bayesian pooling technique for estimating the dynamic link travel time of networks. The proposed algorithm has been validated using the field experiment data out of GPS probes and detectors over the roadways and the estimated link travel time from the algorithm is proved to be more useful than the mere arithmetic mean from each traffic source.

• Journal of Welding and Joining
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• v.15 no.6
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• pp.32-40
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• 1997

Solid state diffusion bonding is the joining process performed by creep and diffusion, which is accelerated by heating below melting temperature and proper pressing, in vacuum or shielding gas atmosphere. By this process we can obtain sufficient joint which can't be expected from the fusion welding. For Ti-6Al-4V alloy, the optimum solid state diffusion bonding condition and mechanical properties of the joint were found, and micro void morphology at bond interface was observed by SEM. The results of tensile test showed sufficient joint, whose mechanical properties are similar to that of base metal. 850$^{\circ}$C, 3MPa is considered as the optimum bonding condition. Void morphology at interface is long and flat at the initial stage. As the percentage of bonded area increases, however, small and round voids are found. Variation of void shape can be explained as follows. As for the void shrinkage mechanism, at the initial stage, power law creep is the dominant, but diffusion mechanism is dominant when the percentage of bonded area is increased.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2001.05a
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• pp.332-337
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• 2001

The objective of research is to clarify the interaction between dislocations and precipitates during high temperature creep deformation behaviors of high Mn austenitic steels. After measuring the internal stress in minimum creep rate at 873K, a transmission electron microscope (TEM) observation was performed to investigate the interaction between dislocations and precipitates during high temperature creep deformation. The band width of effective stress and internal stress increased when the nitride precipitates distribute more densely. Fine nitrides disturbed the dislocation movement with pinning the dislocations and perfect dislocations were separated into Shockley partial dislocations by fine nitrides. Coarse nitrides disturbed the dislocation movement with climb mechanism.

• Journal of Applied Reliability
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• v.15 no.4
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• pp.262-269
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• 2015

Accelerated degradation mechanism of the heat-resistant steel for high temperature plant was analysed in terms of microstructure and hardness. In order to simulate the microstructure of the steel actually used at $540^{\circ}C$ in the field, isothermal exposure was carried out at $630^{\circ}C$ up to 4,800 hours. The artificial degradation mechanism was comparatively verified to successfully simulate degradation of the long-time used field material. For the artificially degraded specimens, databases including size and aspect ratio of carbide, chemical composition (i.e., Cr/Mo ratio) of grain boundary carbide were built up. These degradation parameters were suggested as fingerprints for PHM (i.e., prognostics health management) of power plants.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.1
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• pp.156-166
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• 2010

Development of IP network technology creates new service which applying to fusion technologies such as IPTV, VoIP, and so on. Especially, Next generation IP is called IPv6 which will solve the lack of IP. IPv6 is very important on IPTV which needs best quality of service about security, QoS, and bandwidth. In this paper, we constructed experimental network, measured PSNR which computes the peak signal-to-reconstructed video measurement in experimental network environment, analyzed PSNR value. And as a result of measurement, we, Propose optimum network environment for IPTV service provider and transition mechanism designer.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.957-960
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• 2008

The purpose of this study is to explore a safe, advanced, and environment-friendly demolition equipments and their operation methods. As an initial achievement, the capacity of the existing equipments have been evaluated through technical discussions and demonstrations with some experts in the related industry. From these evaluations, it was concluded that a haptic based remote control with force feed-back mechanism and sensor fusion functions would be the most appropriate to the demolition equipments. Therefore, a novel haptic device that is adequately designed for the demolition equipments is proposed in this paper. Top-down demolition method is also proposed, which is very effective in the demolition of high-rise buildings.

• Bulletin of the Korean Chemical Society
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• v.25 no.6
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• pp.838-842
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• 2004

Amyloid peptide (A${\beta}$) is the major component of senile plaques found in the brain of patient of Alzheimer's disease. ${\beta}$-amyloid peptide (25-35) (A${\beta}$25-35) is biologically active fragment of A${\beta}$. The three-dimensional structure of A${\beta}$25-35 in aqueous solution with 50% (vol/vol) TFE determined by NMR spectroscopy previously adopts an ${\alpha}$-helical conformation from $Ala^{30}$ to $Met^{35}$. It has been proposed that A${\beta}$(25-35) exhibits pH- and concentration-dependent ${\alpha}-helix{\leftrightarrow}{\beta}$sheet transition. This conformational transition with concomitant peptide aggregation is a possible mechanism of plaque formation. Here, in order to gain more insight into the mechanism of ${\alpha}$-helix formation of A${\beta}$25-35 peptide by TFE, which particularly stabilizes ${\alpha}$-helical conformation, we studied the secondary-structural elements of A${\beta}$25-35 peptide by molecular dynamics simulations. Secondary structural elements determined from NMR spectroscopy in aqueous TFE solution are preserved during the MD simulation. TFE/water mixed solvent has reduced capacity for forming hydrogen bond to the peptide compared to pure water solvent. TFE allows A${\beta}$25-35 to form bifurcated hydrogen bonds to TFE as well as to residues in peptide itself. MD simulation in this study supports the notion that TFE can act as an ${\alpha}$-helical structure forming solvent.

• Korean Journal of Microbiology
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• v.42 no.3
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• pp.230-234
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• 2006

To study the mechanism of syncytium formation, novel syncytia-inducing ecotropic murine retrovirus was used. Our previous result showed that amino acid substitutions at the RBD (receptor binding domain) of envelope glycoprotein contribute to syncytium formation. In this study, we have investigated if this fusion phenomenon could occur with retroviral vectors pseudotyped with the novel syncytia-inducing ecotropic murine leukemia virus Env. We have found that these vectors were not able to mediate virus-to-cell fusion in M. dunni murine cell lines. These findings indicate that syncytia-inducing ecotropic murine leukemia virus is capable of generating syncytia during its replication. There was also no correlation between the level of ecotropic murine leukemia virus receptor (mCAT-1) and the fusogenic effect.

• The Journal of the Convergence on Culture Technology
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• v.4 no.2
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• pp.211-216
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• 2018

Separation technology combining adsorption and membrane is expected to be applied in many fields such as water treatment. In this fusion technique, a functional carbon membrane having a carbon whisker grown on the surface of the membrane was developed to inhibit membrane fouling, which is a problem in the membrane separation process. In this study, to elucidate the mechanism of manufacturing the functional carbon membrane, the membrane was pretreated with the polymer latex of each mixing ratio and the membrane was formed by the CVD (Chemical Vapor Deposition) method. The membrane was analyzed by scanning electron microscope (SEM), CHN analyzer (Elemental Analyzer), and X-ray diffraction (XRD). As a result, the diameter and density of carbon whiskers were higher in case of polyvinyl di-chloride (PVdC): polyvinyl chloride (PVC) = 4.5: 55. It seems possible to control the diameter and density of the carbon whiskers according to the hydrogen content of the polymer latex.