• Title/Summary/Keyword: Fundamental Factors

Search Result 1,288, Processing Time 0.032 seconds

Association of Cytokine Gene Polymorphisms with Gastritis in a Kazakh Population

  • Kulmambetova, Gulmira Nigmetzhanovna;Imanbekova, Meruert Kuatbekovna;Logvinenko, Andrey Alexeevich;Sukashev, Adilbek Temirzhanovich;Filipenko, Maxim Leonidovich;Ramanсulov, Erlan Mirhaidarovich
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.18
    • /
    • pp.7763-7768
    • /
    • 2014
  • Background: Gastritis and gastric cancer are the most common diseases in the Kazakh population. Polymorphisms in genes coding of cytokines have been played important role with gastric disease risk. The risk alleles of cytokines in patients with gastritis can predict the risk of developing gastric cancer. The aim of this study was to investigate cytokine gene polymorphisms as risk factors for the development of gastritis in a case-control study with gastritis patients and healthy individuals from the Kazakh ethnic group, living in North Kazakhstan. Materials and Methods: The polymerase chain reaction followed by direct sequencing were used for detection of two functional polymorphisms in the IL1 gene family, and TaqMan SNP Genotyping Assay Sets were applied for three potentially functional polymorphisms in the IL10 gene, and one in the TNFA promoter. Results: Association analysis of studied allelic variants and the development of gastritis in H. pylori-positive patients showed that IL1B -31C/C, IL1B -511T/T and IL1RN -2/2 allelic variants were associated with development of gastritis (OR=1.8 (1.07-3.16), p=0.025; OR=1.7 (1.04-2.99), p=0.035, and OR=4.92 (2.45-9.85), p<0.001) respectively. Haplotype C-Т that combines both homozygous allelic variants of IL1B gene also had a statistically significant association with slightly higher OR (OR: 1.43, 95% CI: 1.08-1.88). Conclusions: The data from the current study showed that the genotype IL-1B -511Т/-31C-IL1-RN-2 and H. pylori infection increase risk of gastritis in the Kazakh population. That genotype combination might be a factor increasing the risk of developing gastric cancer.

The Present Situation and Desired Future Directions of Fisheries Social Education (수산사회교육의 현상황과 발전 방향)

  • KIM, Sam-Kon;KIM, Tae-Un
    • Journal of Fisheries and Marine Sciences Education
    • /
    • v.15 no.2
    • /
    • pp.206-218
    • /
    • 2003
  • In spite of the importance of a fishing industry, neither any terminology defined in details nor academic systems to educate the workers in the fishery were established in the fisheries social education. The fisheries social education was considered to be the practical area around the actual fields. Therefore, on-site education was very important. Accordingly, this study collected and analyzed theoretical basis of a social education and data on the rural adult education and examined the actual status of the fishing industry in Korea and fisheries extension services enterprise and fisheries developmental enterprise corresponding to the actual fisheries social education conducted in Korea. On the basis of these frames, this study summarized the direction for the progress of fisheries social education that has not been studied until now for the purpose of suggesting the future directions of the fisheries social education as follows; The recognition on the importance of fisheries social education and fundamental researches in the fisheries social education should be extended. The practical development of fisheries social education should be realized. Fisheries extension services enterprise should be evolved by fishermen. The abilities of instructors in the fisheries social education should be improved. The academic factors in the fisheries social education should be emphasized. Inter-disciplinary and multi-disciplinary approaches should be adopted. Various programs should be developed for the progress of the fisheries social education. The exclusive department in charge of the fisheries social education should be established. The information system for the fisheries social education should be secured. The industry, academic organizations and the organs should make cooperation. The fisheries social education should be provided by general social education institutions for the progress. The fisheries development should be deployed on the basis of environmental preservation. It is necessary to deploy the new fishing village movement like the Saemaul movement to the fisheries. The administrative and financial supports for the fisheries social education should be expanded. It is essential to cultivate the future fishermen for the international competitiveness.

Plant breeding in the 21st century: Molecular breeding and high throughput phenotyping

  • Sorrells, Mark E.
    • Proceedings of the Korean Society of Crop Science Conference
    • /
    • 2017.06a
    • /
    • pp.14-14
    • /
    • 2017
  • The discipline of plant breeding is experiencing a renaissance impacting crop improvement as a result of new technologies, however fundamental questions remain for predicting the phenotype and how the environment and genetics shape it. Inexpensive DNA sequencing, genotyping, new statistical methods, high throughput phenotyping and gene-editing are revolutionizing breeding methods and strategies for improving both quantitative and qualitative traits. Genomic selection (GS) models use genome-wide markers to predict performance for both phenotyped and non-phenotyped individuals. Aerial and ground imaging systems generate data on correlated traits such as canopy temperature and normalized difference vegetative index that can be combined with genotypes in multivariate models to further increase prediction accuracy and reduce the cost of advanced trials with limited replication in time and space. Design of a GS training population is crucial to the accuracy of prediction models and can be affected by many factors including population structure and composition. Prediction models can incorporate performance over multiple environments and assess GxE effects to identify a highly predictive subset of environments. We have developed a methodology for analyzing unbalanced datasets using genome-wide marker effects to group environments and identify outlier environments. Environmental covariates can be identified using a crop model and used in a GS model to predict GxE in unobserved environments and to predict performance in climate change scenarios. These new tools and knowledge challenge the plant breeder to ask the right questions and choose the tools that are appropriate for their crop and target traits. Contemporary plant breeding requires teams of people with expertise in genetics, phenotyping and statistics to improve efficiency and increase prediction accuracy in terms of genotypes, experimental design and environment sampling.

  • PDF

Fundamental Study of Energy Harvesting using Thermoelectric Module on Road Facilities (열전소자를 활용한 도로구조물에서의 에너지 하베스팅 기초 연구)

  • Lee, Jae-Jun;Kim, Dae-Hoon;Lee, Kang-Hwi;Lim, Jae-Kyu;Lee, Seung-Tae
    • International Journal of Highway Engineering
    • /
    • v.16 no.6
    • /
    • pp.51-57
    • /
    • 2014
  • PURPOSES : An conventional method for electric power generation is converting thermal energy into mechanical energy then to electrical energy. Due to environmental issues such as global warming related with $CO_2$ emission etc., were the limiting factor for the energy resources which resulting in extensive research and novel technologies are required to generate electric power. Thermal energy harvesting using thermoelectric generator is one of energy harvesting technologies due to diverse advantages for new green technology. This paper presents a possibility of application of the thermoelectric generator's application in the direct exchange of waste solar energy into electrical power in road space. METHODS : To measure generated electric power of the thermoelectric generator, data logger was adopted as function of experimental factors such as using cooling sink, connection methods etc. Also, the thermoelectric generator、s behavior at low ambient temperature was investigated as measurement of output voltage vs. elapsed times. RESULTS : A few temperature difference between top an bottom of the thermoelectric generator is generated electric voltage. Components of an electrical circuit can be connected in various ways. The two simplest of these are called series and parallel and occur so open. Series shows slightly better performance in this study. An installation of cooling sink in the thermoelectric generator system was enhanced the output of power voltage. CONCLUSIONS : In this paper, a basic concepts of thermoelectric power generation is presented and applications of the thermoelectric generator to waste solar energy in road is estimated for green energy harvesting technology. The possibility of usage of thermoelectric technology for road facilities was found under the ambient thermal gradient between two surfaces of the thermoelectric module. An experiment results provide a testimony of the feasibility of the proposed environmental energy harvesting technology on the road facilities.

Optimal Transducer Positions of an Active Noise Control System with an Opening in an Enclosure (능동방음벽 시스템에서의 제어음원 위치에 관한 고찰)

  • 백광현
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.14 no.2
    • /
    • pp.164-171
    • /
    • 2004
  • Active control techniques have been used in wide areas of noise and nitration control engineering and a noise barrier is one of them. Omoto's work in 1993 would be one of the fundamental and systematic studies on the actively controlled noise barrier, in which he used equal number of control sources and error sensors. The error sensors were placed uniformly along the top edge of the noise barrier with equal distance apart and the control sources were placed in the exactly same way some distance apart from the error sensors. Since then, a couple of studies were made on the secondary sources'arrangement rather than the optimality of secondary source positions. Shao's results showed that arc shaped arrangement for secondary sources is better than the straight line one, and later work of Yang showed that the more important factor is the average distance between the primary source and secondary sources. However, since these studies were all executed with a simple uniform distribution of the secondary sources along the straight line or arc, it is difficult to conclude which arrangement is superior In order for the fare comparison. the optimality of the source positions in each arrangement must be given in prior. The primary goal of this study is focused on this aspect and some major factors were investigated and compared. The computer simulation results showed that the arc shaped arrangement is marginally better than the straight line one, and more importantly slightly tuned position can greatly improve the performance of the control system.

Perceptual Evaluation of Noise Sources in a Chamber for Residential and Working Environment (주거 및 사무환경 챔버에서의 생활소음에 대한 감성적 평가)

  • Jeon, Jin-Yong;Kim, Kyong-Ho;Jung, Jeong-Ho;Ryu, Jong-Kwan;Cho, Moon-Jae
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.12 no.6
    • /
    • pp.437-444
    • /
    • 2002
  • This paper is to provide the basic way of a acoustical evaluation and efficient control noise by investigating the limits of perceptual loudness of living environment and by finding out any correlation between Physical characteristics of noise and psychoacoustic parameters. The limits of perceptual loudness were selected by the subjects in a chamber for residential and working environment. And the noise sources were analyzed to find out whether there is any correlation with Zwicker parameters and ACF factors. In this study especially, to set up the domestic evaluation grade about floor impact noise. we'd like to suggest the loudness Perception research result as fundamental resource for setting up the evaluation grade through the result that is based on annoyance. In the result of this research, upper limit of heavy-weight impact noise was L-60, and lower limit of it was L-50. On the other hand, upper limit of light-weight impact noise was L-70, and lower limit of it was L-55. It seemed that the loudness of noise from vacuum cleaner noise does not affect its perceived noisiness. Noises implicated In human such as floor walking noise and talking sound, are the most irritating noise in office environment.

Health Condition and Work-related Musculoskeletal Disorders in Greenhouse Vegetable Farmers (시설채소 농업인의 건강 상태 및 근골격계 질환 실태)

  • Kim, Kyung Ran;Choi, Jeong Hwa;Lee, Kyung Suk;Song, Eun Young
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.18 no.1
    • /
    • pp.49-61
    • /
    • 2008
  • The objective of this study is to survey the risk factors of greenhouse vegetables farmers' work-related musculoskeletal disorders(MSDs). To offer the fundamental data for agricultural improvement of greenhouse vegetable farms, the questionnaire of MSDs and heath condition were carried out. A group of 736 workers(males=492, females=244) in 6 branches constitutes the population and database for the analysis between 2004 and 2005. The sample branch was chosen based on paper are watermelon, strawberry, tomato, melon, cucumber, lettuce. The results are as follows: 1. Smoking rates in cucumber and tomato is the highest. 2. Drinking rates in strawberry, cucumber and lettuce is the highest in males, watermelon and melon are the highest in females. 3. Regular exercise rates in melon are the highest. 4. Physical and mental fatigue in females is higher than that of males in most crops except melon. That of strawberry and tomato is the highest. 5. The prevalence rates of medical diagnosed diseases are higher in order of osteoarthritis, herniated nucleus pulposus(HNP), and hypertension. That of strawberry, melon, and cucumber is high in case of osteoarthritis; Strawberry, melon, and watermelon are high in case of HNP. 6. Prevalence rates of musculoskeletal symptoms among the various pain areas are higher in order of low back, knees, and shoulders. That of tomato and watermelon is high in case of low back; strawberry and tomato are high in case of knees. These results can be used practically for agricultural improvement of greenhouse vegetables farms to prevent MSDs.

A Study on Industrial Safety Accidents Treated at A Primary Care Clinic (의원방문 근로자들의 업무상 사고.부상 실태에 관한 연구)

  • Park, Jae-Hong;Kim, Jeong-Won;Kim, Jong-Eun;Cho, Young-Ha;Moon, Deog-Hwan
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.18 no.1
    • /
    • pp.72-79
    • /
    • 2008
  • This study was surveyed to assess the status of safety accidents occurred in work-places and prepare the fundamental data and prevent the safety accidents. The authors reviewed and analysed the charts of accident cases treated at a primary care clinic in A city from January 1991 to December 2006. The data were classified according to the USA Standards Institute and International Labour Organization method. We analyzed the data using SPSS program. The results were as follows : 1. The total cases of accidents were 455 for 8 years. 2. Accidents were mostly common in the workers who are in thirties and forties age(84.4%). 3. As season variation, spring and summer were common than others, but there was no statistical significance on season, month and weekday. 4. The most frequent injured part of the body were hand and finger, which was 36.0% among total cases. 5. According to the accidents type, cases of caught in, under or between were most frequently observed as 53.9% of the total cases. 6. The most common source of injuries was power machine(50.5%). 7. According to the unsafe acts, cases of carelessness and unsafe information were most frequently observed as 71.2% of the total cases. 8. Admission rate(5.5%) and official report rate(2.2%) were very low rate. As above results, the authors recommend to prepare the systemic control programs on environmental and human factors of safety accidents such as improving the working conditions, working facilities, working methods and safety education, and control of working time for working day.

A Study about symbolic nature of the concepts of Jing(精).Qi(氣).Shen(神).Hun(魂).Po(魄) -A psychological consideration- (정(精).氣(기).神(신).혼(魂).백(魄) 개념의 상징성에 관한 연구 -분석심리학적 고찰-)

  • Rhi, Su-Jin;Gu, Byung-Su
    • Journal of Oriental Neuropsychiatry
    • /
    • v.11 no.1
    • /
    • pp.103-113
    • /
    • 2000
  • The aim of this study is to review the concepts of Jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) in the light of the Jungian psychology. According to the explanations of the Jungian psychology human beings have archetypes-a priori conditioning factors-in the collective unconscious. These archetyps are concerned with common concepts conceived by mankind about the fundamental elements which constitute the universe and the existence. The archetype is perceived in a symbol, hence Jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) also are these symbolic representations which had common background of mankind. The meaning of Jing(精) is emphasized as psychic and physical elements, and concerned with instinct. Qi(氣) corresponds to Jung's definition of libido as life energy. The concept of Shen(神) has the value of the self archetype as whole psyche's president principle. Hun(魂) and Po(魄) are intuitive notions of the Orient compared with Animus and Anima which are characteristic representations. However from a standpoint of autonomous energy as archetype the difference would be diminished. Considering each purpose of Hun(魂) and Po(魄) Hun(魂) has a intention of integrating the unconscious flux into consciousness while Po(魄) has a tendency toward instinct to secure a body. It is precious to recognize deeply that these concepts of jing(精) Qi(氣) Shen(神) Hun(魂) Po(魄) play an important part which mediate between the unconscious and consciousness, psyche and body as symbols.

  • PDF

Analysis on the Status and Needs of Training in Assistive Technology of Pediatric Physical Therapist and Pediatric Occupational Therapist (소아물리치료사와 소아작업치료사의 보조공학 교육훈련 실태 및 요구 분석)

  • Kim, Kyoung-A;Jeong, Dong-Hoon
    • Journal of the Korean Society of Physical Medicine
    • /
    • v.8 no.1
    • /
    • pp.99-109
    • /
    • 2013
  • PURPOSE: This study was designed to evaluate the current state of training in assistive technology(AT) for pediatric physical therapists(PPTs) and pediatric occupational therapists(POTs), in addition, investigate therapists' preferred training methods and contents. The eventual purpose was to suggest the essential fundamental factors to adapt the assistive technology in clinics. METHODS: The subject of this study were 167 therapists(98 PPTs and 69 POTs) who work at general hospitals, welfare center, facilities for the disabled, and special education school in Seoul and Gyeonggi province. Frequency analysis and Chi-squared test were used. RESULTS: Significant numbers of PPTs(66 therapists, 67.3%) and POTs(50 therapists, 72.5%) answered that they had received training in AT. More than 48% answered no training experience or low adequacy in each classification scheme for questions. The most difficulty in the training was indicated by lack of education opportunity(90 therapists, 53.9%). The most required device training was seating and position device training(43 therapists, 21.9%) for PPTs and orthosis and prosthesis device training(29 therapists, 21.0%) for POTs. In assistive technology service, PPTs needed evaluation to AT device training(69 therapists, 35.2%) and POTs needed evaluation to disabilities for AT training(41 therapists, 29.7%). Both therapists answered that the most effective training is continuous education(52 therapists, 31.1%) and college education(48 therapists, 28.7%). CONCLUSION: Our findings indicate that PPTs and POTs need more opportunities for training in AT. For effective clinical app lication of AT, there should be continuous education such as on-the-job training, mentoring program, technical manual, and college education.