• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3377-3380
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• 2016

The proportion of lung cancer patients under 50 years old is small at approximately 5-10%, but as with patients older than 50, the number is on the rise. Although lung cancer treatment strategies have undergone extensive transformation in recent years based on the presence or absence of oncogenic driver mutations, there are few reports regarding these mutations in the young or the relationship between clinical setting and prognosis. Therefore, we conducted a study of clinical features in 36 patients under the age of 50 who were diagnosed with primary lung cancer from October 2008 to November 2015. The 22 patients in stages I through III A underwent operations, and all 17 whose lung cancer were detected through screening were candidates for surgery. Gene analysis was conducted for 26 (72.2%); 10 (38.5%) were positive for EGFR gene mutations, and ALK gene translocation was present in 4 (15.4%). In stage IV patients, the median progression free survival (PFS) in the ALK translocation positive and negative patients was 518 days and 130 days, respectively, and the median overall survival (OS) was not reached and 280 days, respectively. A trend toward extended PFS (p=0.203) and OS (p=0.056) was observed in patients positive for ALK translocation. We must strive for early detection by increasing screening rates and evaluate oncogenic driver mutations important for prognosis of lung cancer in the young.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10b
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• pp.54-59
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• 1993

This paper presents a method of estimating 3-D surface geometrical features that are necessary for 3-D object recognition and image interpretation. The features, such as surface needle maps and curvatures, are computed from range or intensity images. In general, the range and intensity images are prone to noises, and hence the features computed by differentiation calculi on such a noisy image are hardly applicable to industrial recognition tasks. In our approach, we try to obtain a more accurate estimate of the features by using a least-squares minimization procedure subject to local curvature consistency constraints. The algorithm is robust with respect to noises and is completely independent of the viewpoint at which the image is taken. The performance of the ajgoritlim is evaluated using both synthetic data and real intensity images.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.541-544
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• 2004

Recently, the heat island phenomenon in which the temperature of a city part rises from the circumference ground has developed into a big problem. In this study, we aimed at examining the impact of increasing vegetation in urban areas to reduce the heat island phenomenon by taking the Fukuoka City of Japan as a case. In order to discuss the relation between vegetation environment and the heat island phenomenon, we have calculated Normalized Difference Vegetation Index (NDVI) and mapped the spatial vegetation distribution. These are then compared with the heat island phenomenon investigations in Fukuoka City. The results of the study revealed that the areas showing comparatively lesser heat island phenomenon are those having increased vegetation.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.438-443
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• 2005

Handy paint rollers with simple or no patterns are generally used to transcribe its design to a wall just after painting. However, the types of the patterns are limited to several conventional ones, so that interior planners' or decorators' demands are gradually tending to getting attractive roller designs. In order to obtain abundant kinds of the roller designs, a new advanced 3D machining method should be established for cylindrical models. In this paper, a post-processor that can generate suitable NC data is proposed for multi-axis NC machine tools with a rotary unit. The 3D machining system with the post-processor is also presented for an attractive interior decorating. The machining system allows us to easily transcribe the relief designs from on a flat model to on a cylindrical model. The effectiveness of the proposed 3D machining system using the post-processor is demonstrated through some machining experiments.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.332-335
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• 1999

The purpose of this study is to make clear that the relationship between the directional properties of late arriving sound and listener envelopment (LEV). Psycho-acoustical experiments are performed with an objective measure of inter-aural cross-correlation(IACC) in order In predict whether LEV is perceived equally in two kinds of sound fields with horizontal or vertical component of late arriving sound. It is found that LEV is affected by not horizontal component of late arriving sound but also vertical one.

• Journal of Photoscience
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• v.7 no.1
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• pp.9-13
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• 2000

An alternately assembled polycation-anionic dye film was prepared on a precursor assembly of poly(allylamine)hydrochloride (PAH) and poly(sodium styrenesulfonate) (PSS) or of poly (djallyldimethyl)ammonium chloride (PDDA) and PSS. The (PAH/PSS) precursor assembly gave better adsorptivity to the anionic dye than the (PDDA/PSS) one. Four kinds of anionic dyes (EB-T, AR-17 AR-18, AR-27) with different numbers of sulfonate substituents were compared. The extent of dye assembling was higher for the dye with a smaller number of sufonate substituents. Second harmonic generation (SHG) was clearly observed from the films. The SHG signal and the absorption intensity correlated well up to four polycation/dye bilayers, while further assembly did not increase the SHG signal appreciably. Second order nonlinear coefficients for ten bilayer assemblies were the order of pm/V.

• IEIE Transactions on Smart Processing and Computing
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• v.2 no.4
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• pp.216-225
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• 2013

This paper discusses the issues regarding an abnormal V-shaped error confronting algebraic-based deconvolution process. Deconvolution was applied to an analysis of the effects of the Random Telegraph Noise (RTN) and Random Dopant Fluctuation (RDF) on the overall SRAM margin variations. This paper proposes a technique to suppress the problematic phenomena in the algebraic-based RDF/RTN deconvolution process. The proposed technique can reduce its relative errors by $10^{10}$ to $10^{16}$ fold, which is a sufficient reduction for avoiding the abnormal ringing errors in the RTN deconvolution process. The proposed algebraic-based analyses allowed the following: (1) detection of the truncating point of the TD-MV distributions by the screening test, and (2) predicting the MV-shift-amount by the assisted circuit schemes needed to avoid the out of specs after shipment.

• Proceedings of the Korea Water Resources Association Conference
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• 2001.05a
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• pp.15-24
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• 2001

This study introduces an integrated decision support system (DSS) for the water supply system in Fukuoka City, Japan. The objective is to conceive a comprehensive tool that may aid decision-makers to derive the best water supply alternatives from a multi-reservoir system in order to minimize the long-term drought damages and threat of water shortage. The present DSS consists of graphical user interface (GUI), a database manager, and mathematical models for runoff analysis, water demand forecasting, and reservoir operation. The methodology applied explicitly integrates the drought risk assessment based on the concept of reliability, resiliency, and vulnerability, as constraints to derive the management operation. The application of the DSS to the existing water supply system in Fukuoka City was found to be an efficient tool to facilitate the examination of a sequence of water supply scenarios toward an improved performance of the actual water supply system during periods of drought.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6249-6256
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• 2013

One-carbon metabolism plays an important role in colorectal carcinogenesis. Meta-analyses have suggested protective associations of folate and vitamin $B_6$ intakes with colorectal cancer primarily based on studies in Caucasians, and genetic polymorphisms pertaining to the folate metabolism have been a matter of interest. Less investigated are the roles of methionine synthase (MTR) and thymidylate synthetase (TS) polymorphisms in colorectal carcinogenesis. In a study of 816 cases and 815 community controls in Japan, we investigated associations of dietary intakes of folate, methionine, vitamin $B_2$, vitamin $B_6$, and vitamin $B_{12}$ with colorectal cancer risk. The associations with MTR 2756A>G, MTRR 66A>G, and TSER repeat polymorphism were examined in 685 cases and 778 controls. Methionine and vitamin $B_{12}$ intakes were inversely associated with colorectal cancer risk, but the associations were totally confounded by dietary calcium and n-3 fatty acids. The other nutrients showed no association with the risk even without adjustment for calcium and n-3 fatty acids. The TSER 2R allele was dose-dependently associated with an increased risk. The MTR and MTRR polymorphisms were unrelated to colorectal cancer risk. There was no measurable gene-gene or gene-nutrient interaction, but increased risk associated with the TSER 2R allele seemed to be confined to individuals with high folate status. This study does not support protective associations for folate and vitamin $B_6$. The TSER 2R allele may confer an increased risk of colorectal cancer. The role of the TSER polymorphism in colorectal carcinogenesis may differ by ethnicity.

• Communications of the Korean Mathematical Society
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• v.29 no.4
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• pp.555-568
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• 2014

A set with an operation defined on a family of subsets is studied. The operation is used to generalize the topological space itself. The operation defines the operation-open subsets in the set. Relations are studied among two types of the interiors and the closures of subsets. Some properties of maximal operation-open sets are obtained. Semi-open sets and pre-open sets are defined in the sets with operations and some relations among them are proved.