• 한국어병학회지
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• 제21권1호
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• pp.67-79
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• 2008

This study was conducted to find out biological response of bivalves exposed to tributyltin chloride(TBTCl). The results of the study confirmed that TBTCl induce the reduction of oxygen consumption rateand histopathological feature in the gill structure of equilateral venus, Gomphina veneriformis. The experi-mental groups consisted of a control and 3 TBTCl exposure groups (0.4, 0.6 and 0.8 yg TBTCl L') and theexperimental period was 36 weeks. For histological analysis, gill tissues were fixed in Bouin's fluid andthen stained H-E stain, AB-PAS (PH 2.5) reaction and Masson's trichrome stain after having serially sec-tioned the tissue by paraffin method at thickness of 4-6 (an. The oxygen consumption rate was not signifi-cantly different between the control and exposure groups at 4 weeks, but in all exposure groups at 28 weeks,it was significantly different to the control. Gill of G. veneriformis had demibranch that attached two sheetsof lamellae and a lamella was composed of numerous filaments, numbering 25 on average. The frontal fila-ment zone had three types of cilia; frontal, latero-frontal and lateral depending on locations while the lateralcilia were the longest and largest in number. The mucous cells observed in filaments were more abundant in(542c) in AB-PAS (PH 2.5) reaction. Gill exposed to TBTCl was extended hemolymph sinus and increased hemocytes at 4 weeks, and then it showed increases of mucous cells and partially disappearance of frontalcilia. In the group of 0.8 yg TBTCl L' at 12 weeks, hypertrophy of frontal and latero-frontal epithelia wasobserved. Also it observed m decrease of mucous cell containing weekly acid mucosubstance and appearedpartially destruction muscle fiber bundle, In the groups of 0.4 and 0.6 ug TBTCl L' at 36 weeks, it appearedpartially modification of epithelia and in 0.8 us TBTCl L' group, observed filaments that come out chiti-nous rod from disappearance of frontal and latero-frontal epithelia.

• KSBB Journal
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• 제18권2호
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• pp.100-106
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• 2003

의학, 약학적으로 작용이 뛰어난 약리성분이 인체 내에서 상처 부위에 얼마나 빨리 도달하여 치료를 하는지를 알기 위하여 혈장 단백질과 약리성분의 결합력을 연구하는 새로운 연구 분야가 HPFA이다. 본 연구는 인체 내에 존재하는 혈장단백질과 항암제로서 알려져 있는 (S)-perillyl alcohol의 결합력과 결합 매개변수를 구하기 위하여 on-line frontal analysis HPLC system을 적용하였다. Develosil 100 Diol 5 (10 cm $\times$ 4.6 mm I.D.)의 HPFA 컬럼을 이용하였고, 이동상은 인산완충용액(pH = 7.4, I = 0.17)을 이용하였다. UV wavelength 205 nm에서 실험을 수행하였고, 주입 부피는 본 실험 조건인 혈장 단백질이 350 rM일 경우에 최대의 혈장 단백질과 결합되지 않은 약리성분의 농도를 갖게 되는 600 ${\mu}\ell$으로 정하였다. Scatchard analysis를 통한 연구 결과로 혈장 단백질인 HSA와 (S)-perillyl alcohol의 결합 매개변수(K)와 단위 HSA에 대한 S-POH의 결합 위치의 수(n)는 각각 K : 2.05 $\times$ $10^{6}$ [M$^{-1}$], n : 0.00428로 실험적으로 구하였다

• 한국자동차공학회논문집
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• 제11권1호
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• pp.211-216
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• 2003

A frontal offset impact model Oat can simulate the 40% offset frontal impact into deformable barrier regulated in EU Directive 96/79 EC has been developed. Engine rotation effects are also considered in the model. Distributed 11 masses and characteristics of 23 nonlinear springs comprising the model are determined based on both the stick-model analysis under the general specification of car and the dynamic characteristics of car structure. It is demonstrated that simulated acceleration-time curve for passenger part is in good agreement with test data obtained by NHTSA.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
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• pp.1003-1006
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• 2006

Frontal regions in midlatitude storms exhibit a wide range of behavior, which can be observed by remote sensors. These include decay, strengthening, rotating, and sometimes spawning of new cyclones. Here we refine and apply recent theories of front and frontal wave development to a case of a front clearly observed and analyzed in remote sensing data. By applying innovative analysis techniques to the data we assess the respective roles of ageostrophy, background deformation, and Boundary Layer processes in determining the evolution of the surface front. Our analysis comprises of diagnosis of the terms appearing in the vorticity and divergence equations using remotely sensed observations.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.619-620
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• 2006

In this paper, the CAE Service System for Collaborative Engineering Environment with web services and Multi-frontal Method has been investigated and developed. The enabling technologies such as SOAP and .NET Framework play great roles in the development of integrated distributed application software. In addition to the distribution of analysis modules, numerical solution process itself is again divided into parallel processes using Multi-frontal Method for computational efficiency. We believe that the proposed approach for the analysis can be extended to the entire product development process for sharing and utilizing common product data in the distributed engineering environment.

• 대한치과교정학회지
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• 제38권4호
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• pp.252-264
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• 2008

본 연구는 안면비대칭 환자의 악교정수술 시 경조직 이동에 따른 연조직 변화를 정면에서 평가함으로써 정면 얼굴 이미지 시뮬레이션 프로그램 개발에 도움이 되고자 시행되었다. 안면비대칭이 동반된 하악골 수술 예정 환자 45명을 대상으로 정모 두부방사선규격사진과 얼굴사진(photo)을 술전 및 술후에 각각 같은 각도로 촬영한 후, 술전 및 술후의 방사선사진을 이용하여 경조직 계측점의 변화를, 얼굴사진을 이용하여 연조직 계측점의 변화를 수평 및 수직으로 구분하여 각각 측정한 후 경조직 변화에 따른 연조직 변화를 비교 분석하였다. 연조직 변화와 경조직 변화의 상관성을 살펴본 결과 수평 방향, 수직 방향 모두에서 전반적으로 낮은 상관성을 보였으며, 1 : 1 mean ratio 산출을 위하여 서로 상관성이 가장 높은 경조직 계측점을 연조직 계측점별로 선택한 결과 직하방에 있는 경조직보다는 다소 멀리 떨어져 있는 경조직 계측점이 선택되는 경우가 많이 나타났다. 경조직 변화를 이용하여 연조직 변화를 예측할 수 있는 회귀방정식을 연조직 계측점별로 산출한 결과 연조직 수평변화 예측에 경조직 수직변화도 사용되고 연조직 수직변화 예측에 경조직 수평변화도 사용되었으며, 수평과 수직변화 모두에서 가장 설명력이 높은 방정식은 연조직 menton에서 나타났다. 이상의 연구결과 하부 경조직 계측점과 상부 연조직 계측점의 비율을 이용하는 1 : 1 mean ratio 방법은 불가능한 것으로 나타난 반면 회귀분석을 이용한 연조직 변화 예측은 임상에 도움이 될 수 있는 것으로 나타나 정면 이미지의 경우 컴퓨터를 이용한 시뮬레이션 프로그램이 반드시 필요함을 시사하였다.

• 자동차안전학회지
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• 제15권4호
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• pp.88-94
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• 2023

The seating postures of passengers in the automated driving vehicle are possible in atypical forms such as rear-facing and lying down. It is necessary to improve devices such as airbags and seat belts to protect occupants from injury in accidents of the automated driving vehicle, and collision safety evaluation tests must be newly developed. The purpose of this study is to define representative types of head-on collision accidents to develop collision standards for autonomous vehicles that take into account changes in driving behavior and occupants' postures. 150 frontal collision cases remained by filtering (accident videos, images, AIS 2+, passenger car, etc…) and random sampling from approximately 320,000 accidents claimed by a major insurance company over the past 5 years. The most frequent accident type is a head-on collision between a vehicle going straight and a vehicle turning left from the opposite side, accounting for 54.7% of all accidents, and most of these accidents occur in permissive left turns. The next most common frontal collision is the center-lane violation by drowsy driving and careless driving, accounting for 21.3% of the total. For the two types above, data such as vehicle speed, contact point/area, and PDOF at the moment of impact are obtained through accident reconstruction using PC-Crash. As a result, two types of autonomous vehicle crash safety test scenarios are proposed: (1) a frontal oblique collision test based on the accident types between a straight vehicle and a left-turning vehicle, and (2) a small overlap collision test based on the head-on accidents of center-lane violation.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.530-537
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• 2016

본 연구는 정면충돌사고를 분석하여 충돌방향과 관련된 운전저의 행동변화를 분석하고, 인체손상정도를 파악해보고자 한다. 연구기간은 2013년 8월~2014년 1월까지로 응급의학 팀에 의해 차량의 손상정도와 인체상해 데이터를 수집하였다. 자료수집에서 사고차량, 사고방향 등은 KIDAS(Korea In-depth Accident Study; 한국형 교통사고 심층조사)와 인체손상정보에 기반을 둔 ISS(Injury Severity Score; 인체손상점수) 내용을 수집하였다. 자료분석은 Minitab 17과 SPSS 22.0을 이용하여 빈도분석과 ANOVA분석을 시행하였다. 분석결과 정면충돌은 12시 방향에서 55.8%로 가장 높게 나타났다. 연령에 따른 정면충돌 방향을 분석해 본 결과 11시방향이 평균 $46.46{\pm}13.47$세, 12시방향이 $44.43{\pm}13.40$세, 1시 방향에서 $52.46{\pm}12.04$세로 통계적으로 유의하게 연령이 높을수록 1시 방향에서 높게 나타났다(p<0.05). 남자의 연령에 따른 정면충돌 방향에서도 11시방향이 $47.10{\pm}13.88$세, 12시방향이 $45.24{\pm}13.78$세, 1시 방향에서 $55.73{\pm}13.38$세로 연령이 증가함에 따라 1시방향의 충돌이 높게 나타났다(p<0.05). 그러나 여자의 경우 연령에 따른 정면충돌 방향에서는 통계적으로 유의하지 않았다(p>0.05). 남녀의 연령에 따른 충돌방향에서의 ISS점수를 비교해봤을 때 남자의 경우 $ISS{\geq}9$에서 12시방향 충돌은 감소하고 ISS<9에서 1시방향 충돌이 증가하였다(p<0.05). 결과적으로 정면충돌방향은 12시 방향에서 가장 높은 빈도로 일어나고, 연령이 증가할수록 정면충돌 방향이 1시 방향으로 높아져 ISS점수가 낮아진다. 따라서 남성에서 12시방향 충돌을 인지하고 핸들을 왼쪽으로 틀어 1시 방향 충돌로 바꾸어 신체손상을 줄이려는 행동을 한다.

• 대한의용생체공학회:의공학회지
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• 제27권4호
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• pp.170-179
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• 2006

The purpose of this study was to investigate the spatiotemporal cortical activation pattern and functional connectivity during visual perception of words. 61 channel recordings of electroencephalogram were obtained from 15 subjects while they were judging the meaning of Korean, English, and Chinese words with concrete meanings. We examined event-related potentials (ERP) and applied independent component analysis (ICA) to find and separate simultaneously activated neural sources. Spectral analysis was also performed to investigate the gamma-band activity (GBA, 30-50 Hz) which is known to reflect feature binding. Five significant ERP components were identified and left hemispheric dominance was observed for most sites. Meaningful differences of amplitudes and latencies among languages were observed. It seemed that familiarity with each language and orthographic characteristics affected the characteristics of ERP components. ICA helped confirm several prominent sources corresponding to some ERP components. The results of spectral and time-frequency analyses showed distinct GBAs at prefrontal, frontal, and temporal sites. The GBAs at prefrontal and temporal sites were significantly correlated with the LPC amplitude and response time. The differences in spatiotemporal patterns of GBA among languages were not prominent compared to the inter-individual differences. The gamma-band coherence revealed short-range connectivity within frontal region and long-range connectivity between frontal, posterior, and temporal sites.

• PNF and Movement
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• 제14권2호
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• pp.131-137
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• 2016

Purpose: The purpose of this study was to compare muscle activities in the frontal plane and scapular plane of the middle fiber and lower fiber of the trapezius muscle at different shoulder abduction angles. Methods: Twenty male and female students in their 20s participated in this study. Each subject maintained shoulder abduction at $75^{\circ}$, $90^{\circ}$, $125^{\circ}$, and $160^{\circ}$ in a standing position and repeated motions three times each in the frontal plane and the scapular plane. While maintaining the motions for 10 seconds in each posture, surface electromyography (EMG) was used to measure muscle activity of the middle fiber and lower fiber of the trapezius muscle. The collected EMG data were normalized using maximal voluntary isometric contraction (MVIC). Differences in muscle activity of the middle fiber and lower fiber of the trapezius muscles according to the angles at each plane were statistically processed using repeated measured analysis of variance, and an independent t-test was used to examine the differences between the two planes at each angle. Results: Muscle activity of the middle and lower trapezius during shoulder abduction in the frontal plane and scapular plane significantly increased as the angles increased (p<.05). However, muscle activity of the middle trapezius was significantly lower in the scapular plane than in the frontal plane for all shoulder abduction angles (p<.05). Conclusion: The results of this study suggest that during shoulder abduction, angles should be different according to the goals, and for training during an acute phase or early phase for functional recovery, it is more efficient to perform the training in the scapular plane than in the frontal plane.