• 대한한의학원전학회지
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• 제24권1호
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• pp.85-93
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• 2011

Wasting-thirst(消渴) occurs due mainly to dryness-heat(燥熱) which by depleting 'Fluid and Humor'(津液) make symptoms of thirst(口渴) swift digestion with rapid hungering(消穀善饑) frequent urination(小便頻數) according to "Internal Classic"(內經). However, the doctors of those days had a tendency to manage wasting-thirst with herbal drugs of dryness-heat or with drugs that tonifies the kidney. Liu Wansu(劉完素) thought that those kinds of drugs intensify gatro-intestinal dryness-heat and consequently could not be suitable for the patients with wasting-thirst. He said that they had mistaken about the relation between five viscera(五臟) and six climate condition(六氣) and that they did not know thoroughly on the theory of branch and root(標本). For preventing the disease of wasting-thirst, Liu Wansu(劉完素) recommended avoiding gatro-intestinal drying caused by the intake of dryness-heat diet, and warned not to deplete 'Fluid and Humor' due to stress-induced fire(火), not to damage yin qi(陰氣) through severe diseases.

• 대한수의학회지
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• 제16권1호
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• pp.97-103
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• 1976

In order to clarify the histopathological changes resulting from nitrate poisoning, rabbits were experimentally poisoned by the oral administration of $KNO_3$ or $NaNO_2$ and examined clinically and histopathologically. In addition, the quantitative changes of glycogen level in hepatic cells were histochemically observed. The results obtained were summarized as follows: 1. Clinical symptoms observed from the acute cases which died within 2 hours after the administration were severe cyanosis of visible mucosa, frequent urination, and dyspnea. However, in chronic cases administrated daily with $KNO_3$ for 43, 50 and 74 days respectively, no marked symptoms were observed. 2. Macroscopic changes observed in acute cases were severe methemoglobinemia, cloudy swelling of hepatic cells, hemorrhage and hyperemia of gastric mucosa, and hyperemia of other organs. In chronic cases there were marked hyperemia, dark-red coloring and increasing of consistency in liver and kidney, and swelling of spleen. 3. Microscopic changes observed in acute cases were hemorrhage and hyperemia of various organs, cloudy swelling and centrilobular necrosis of hepatic cells and necrosis of convoluted tubular epithelium in kidney. In chronic cases there were round cell infiltration of the interlobular connective tissue and epithelial proliferation of interlobular bile ducts in the liver, and necrosis of the convoluted tubular epithelium and proliferation of interstitial connective tissue in kidney, thickening of alveolar septa of lungs, activated hemopoiesis of bone marrow, and myeloid metaplasia of sqlenic pulp. 4. Glycogen storage in liver cells was decreased in acute cases, on the contrary, increased in chronic cases.

• 동의생리병리학회지
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• 제18권1호
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• pp.294-300
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• 2004

The purpose of this study was to investigate the effects of oxibustion on complications of Diabetes Millitus. We collected 23 patients with glycosurea complications in Songeui Oriental Hospital from April, 2003 to July, 2003, and then expremented Moxibustion, medical examinations and laboratory test for 4 weeks. At the symptons change : Among the symptons which the number over 5 persons of patients is reserved, dysaesthesia of limbs, neuralgic pain, urinary frequent urination, dpontaneous perspiration, thirst, decrease of body weight and malaise showed the improvement over 60%(n=23). Level of FBS was don't have the significant meaning however showed the tendency of the desent, and level of HbA1c significantly decreased after treatment(P&0.001)(n=19).

• 대한한방부인과학회지
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• 제34권1호
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• pp.82-92
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• 2021

Objectives: The purpose of this study is to report the clinical effectiveness of Korean medicine treatment on interstitial cystitis. Methods: The patient diagnosed with Interstitial cystitis/Bladder pain syndrome (IC/BPS) was treated with Korean medicine treatment during 22 days of hospitalization. The patient received Korean medicine treatment including herbal medicine, acupuncture, pharmacopuncture, moxibustion, cupping and extracorporeal magnetic stimulation therapy. The effect of treatment on IC/BPS was evaluated through the Numeric Rating Scale (NRS), voiding diary, and Interstitial Cystitis Symptom Index/Problem Index (ICSI/ICPI). Results: After the treatment, the clinical symptoms of IC/BPS such as pelvic pain, pelvic pressure, frequent urination and urinary urgency were improved. Also, the patient had better scores in ICSI/ICPI. Conclusions: This case report proved that the Korean medicine treatment may be effective for improving clinical symptoms of IC/BPS. However, a large-scale clinical study is needed in the future to prove the effectiveness of Korean medicine treatment for IC/BPS.

• 한국임상수의학회지
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• 제38권4호
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• pp.199-203
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• 2021

A 4-year-old Thoroughbred mare was brought to the Korea Racing Authority Equine Hospital with heightened sensitivity to touch of the hindquarter, reluctance to step forward, frequent urination even during training, clitoral winking, tail swinging, tail lifting, and training difficulties due to being in constant heat. The trainer claimed that she was in heat and exhibited reduced performance. Physical and lameness examinations revealed no abnormality. Rectal palpation and transrectal ultrasonography revealed normal reproductive organs and estrus. As she exhibited typical estrous behavior without any other physical conditions, the mare was considered to express undesirable estrous behavior. An intrauterine glass ball was inserted into the mare on ovulation day. However, the estrous behaviors were reduced unsatisfactorily. Additionally, 1 mL of peanut oil was administered on the 10th day after the intrauterine device insertion. The mare returned to training and expressed no undesirable estrous behavior over 30 days after the peanut oil treatment. However, further follow-ups were not conduct as the mare was retired to a farm after a limb injury occurred during training. This is the first report of undesirable estrous behavior in a Thoroughbred mare under the rules of racing in Korea. It is recommended that equine clinicians in Korea consider peanut oil as a therapeutic agent to control mares' estrous behavior-related problems.

• 대한한방내과학회지
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• 제43권5호
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• pp.795-808
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• 2022

Objectives: The purpose of this study is to report two cases of prostate cancer patients whose side effects after surgery were treated with traditional Korean medicine. Methods: Two prostate cancer patients underwent robot-assisted laparoscopic prostatectomy, and both patients were treated with traditional Korean medicine. Subjective discomfort symptoms were evaluated using the Numerical Rating Scale. Adverse events were evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events, version 5.0. Daily life vitality was evaluated by the Eastern Cooperative Oncology Group. Results: After treatment with traditional Korean medicine, discomfort symptoms that occurred after surgery, such as frequent urination, nocturia, insomnia, and depression, all gradually improved, and Eastern Cooperative Oncology Group scores also improved from two points to one point. Additionally, there were no hematologic side effects from the traditional Korean medicine treatment. Conclusions: This case study suggests that traditional Korean medicine may contribute to the improvement of side effects caused by robot-assisted laparoscopic prostatectomy, quality of life, and immunity.

• 한국정보통신학회논문지
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• 제26권9호
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• pp.1266-1271
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• 2022

반려동물 중 반려묘의 비중이 2012년 이후 연평균 25.4%의 증가율을 보이며 증가하는 추세이다. 고양이는 강아지에 비해 야생성이 강하게 남아있기 때문에 질병이 생기면 잘 숨기는 특성이 있다. 보호자가 반려묘가 질병이 있음을 알게 되었을 때는 병이 이미 악화되어진 상태일 수 있다. 반려묘의 식욕부진(식사회피), 구토, 설사, 다음, 다뇨 등과 같은 현상은 당뇨, 갑상선기능항진증, 신부전증, 범백혈구감소증 등 고양이 질병 시 나타나는 증상 중 일부이다. 반려묘의 다뇨(소변 양이 많음), 다음(물 많이 마심), 빈뇨(소변을 자주 봄) 현상을 보호자가 보다 빨리 알아차릴 수 있다면 반려묘의 질병 치료에 크게 도움이 될 것이다. 본 논문에서는 인공지능 디바이스에서 작동하는 1) 자세 예측 DeepLabCut의 Efficient 버전, 2) 객체 검출 YOLO v4, 3) 행동 예측 LSTM 4) 객체 추적은 BoT-SORT를 사용한다. 인공지능 기술을 이용하여 홈 CCTV의 영상에서 반려묘의 행동 패턴 분석과 물그릇의 무게 센서를 통해 반려묘의 다음, 다뇨 및 빈뇨를 예측한다. 그리고, 반려묘 행동 패턴 분석을 통해, 질병 예측 및 이상행동 결과를 보호자에게 리포트 하는, 메인 서버시스템과 보호자의 모바일로 전달하는 애플리케이션을 제안한다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 춘계학술대회
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• pp.165-167
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• 2022

반려동물 중 반려묘의 비중이 2012년 이후 연평균 25.4%의 증가율을 보이며 증가하는 추세이다. 고양이는 강아지에 비해 야생성이 강하게 남아있기 때문에 질병이 생기면 잘 숨기는 특성이 있다. 보호자가 반려묘가 질병이 있음을 알게 되었을 때는 병이 이미 악화되어진 상태일 수 있다. 반료묘의 식욕부진(식사회피), 구토, 설사, 다음, 다뇨 등과 같은 현상은 당뇨, 갑상선기능항진증, 신부전증, 범백혈구감소증 등 고양이 질병 시 나타나는 증상 중 일부이다. 반려묘의 다음(물 많이 마심), 다뇨(소변의 양이 많음), 빈뇨(소변을 자주 봄) 현상을 보호자가 보다 빨리 알아차릴 수 있다면 반려묘의 질병 치료에 크게 도움이 될 것이다. 본 논문에서는 인공지능 서버에서 작동하는 1) 자세 예측 DeepLabCut의 Efficient버전, 2) 객체 검출 yolov4, 3) 행동 예측은 LSTM을 사용한다. 인공지능 기술을 이용하여 홈 CCTV의 영상에서 반려묘의 행동 패턴 분석과 물그릇의 무게 센서를 통해 반려묘의 다음, 다뇨 및 빈뇨를 예측한다. 그리고, 반려묘 행동 패턴 분석을 통해, 질병 예측 및 이상행동 결과를 보호자에게 리포트 하는, 메인 서버시스템과 보호자의 모바일로 전달하는 애플리케이션을 제안한다.

• 한국임상수의학회지
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• 제41권2호
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• pp.71-78
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• 2024

Changes in elimination behavior, including urination and defecation, are common clinical signs of numerous disorders in cats. Therefore, this study attempted to automatically measure the elimination behavior of cats using the litter box and develop an early warning system for the guardian in case of abnormalities. To construct an early warning system for abnormal changes through cat elimination behavior, it consisted of a litter box, an automatic sensor for data collection and data wifi transmission, a server for data analysis, and a mobile phone app for result transmission and early warning. To establish the reference interval (RI), the elimination behavior was monitored for more than 2 weeks using a motion sensor within a litter box in 37 healthy cats and 19 diseased cats. The data were expressed as daily total visits, daily total stay duration, average stay duration per elimination, weekly total visits, and weekly total stay duration. Healthy cats showed median daily total visits of 3 times/day (RI 1.0-7.0) and daily total stay duration of 192 s/day (RI 8.0-452.0). For weekly data, the median total visits were 20 times/week (RI 3.0-35.25) and the median total stay duration was 1,147 s/week (RI 80.0-2,249.5). The average stay duration per elimination was 59 s/elimination (RI 4.67-132.0). Diseased cats showed more frequent elimination behavior than healthy cats (p < 0.001). Otherwise, for each elimination, diseased cats had shorter stay durations than healthy cats (p < 0.001). This study established the RIs of elimination behavior parameters (frequency and duration) in healthy cats. The present study might help guardians and veterinarians detect changes in elimination behaviors in diseased cats at an early stage.

• Parasites, Hosts and Diseases
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• 제24권1호
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• pp.71-76
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• 1986

1985년 10월부터 12월 사이에 본병원에 입원한 2명의 환자로부터 Echinostoma sp. 충란을 검출하였다. 이 환자들에게 praziquantel 10mg/kg을 투여하고 하제를 사용한 후 명명 7마리(제 1 예) 및 2마리(제 2 예)의 E. cinetorchis 충체를 수집 동정하였으며 그 결과를 요약하면 다음과 같다. 1. 제1례의 환자는 충북 청주지역에 거주하는 54세 남자로서 심한 체중감소와 빈혈의 증상으로 병원에 입원하였으며, 제2례는 강원도 정선에 거주하는 71세 남자로서 폐암의 증상으로 병원에 입원하였다. 2. 대편검사에서 검출된 충란의 크기는 제1례가 $98{\times}63{\mu}m$(평균), 제2례는 $100{\times}67{\mu\textrm{m}}$(평균)이었다. 환자들에게 구충제와 하제를 투여하고 수집한 충체는 총9마리였다. 충체의 크기는 체장 19.9mm(평균), 체폭 2.77mm(평균)였고 두관 주위의 두극(좌우 end group spine포함(은 37개가 관찰되었다. 고환은 크기와 수 그리고 위치에서 변이를 나타내었다. 3. 제1례가 생식한 논우렁이(Cipangopaludina sp.)에 대한 본흡충 감염 여부를 규명하기 위하여 청주시내의 한 어류상점에서 논우렁이 50마리를 구입하여 조사하였으나 피낭유충을 검출하지 못하였다.