• 대한한방부인과학회지
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• 제20권2호
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• pp.124-138
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• 2007

Purpose: This study was conducted to investigate the antimicrobial effects of the interior warming herbs on vaginal microbes. Methods: Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Candida albicans and Gardnerella vaginalis were used for vaginitis-induced microbes. Lactobacillus gasseri, Streptococcus spp. and Escherichia coli HB101 were used for normal vaginal florae. And herbs for warming the interior (Zingiberis Rhizoma, Alpiniae Officinari Rhizoma, Aconiti Tuber, Anethi Fructus, Evodiae Fructus, Cinnamomi Cortex Spissus, Caryophylli Flos, Aconiti Tube, Zanthoxyli Pericarpium, Piperis Longi Fructus, Piperis Nigri Fructus) were used in this study. Antimicrobial activities were tested by the change of optical densities (OD) and colony test in vitro. Results: In the results of vaginitis-induced microbes, Anethi Fructus was decreased the OD values on MRSA and Gardnerella vaginalis and Aconiti Tuber was decreased on MRSA. There were no viable MRSA and Gardnerella vaginalis colony forming against Evodiae Fructus, Staphylococcus aureus and MRSA colony forming against Piperis Longi Fructus, Staphylococcus aureus colony forming against Piperis Nigri Fructus and MRSA colony forming against Zanthoxyli Pericarpium. In the results of normal vaginal florae, Zingiberis Rhizoma was decreased the OD values on Streptococcus spp. and all normal vaginal florae were showed viable colony forming against all experimental herbs. Conclusion: According to these results, we can suggest that some kinds of interior warming herbs have antimicrobial effects on vaginal microbes. So there might be needed to make furthermore studies to seek the herbs which have selective antimicrobial effect on pathologic vaginal microbes.

• 대한기계학회논문집
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• 제14권5호
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• pp.1043-1058
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• 1990

본 연구에서는 전자기 성형법에 의한 원통형상의 가공재의 자유 확관성형 가 공에 대해서 유한요소해석법을 이용한 변형 및 응력해석을 수행하였다. 탄소성 재료 모형을 확장하여 변형 경화율이 변형률 및 변형률 속도의 지배를 받는 변형률 속도 종 속 탄소성 재료 모형을 도입하였고, 1차 제하 이후까지 포함하여 고속 성형시 변형률 속도 효과에 의해 발생하는 현상들에 대해서 연구하였다.결과의 비교 및 논의를 위 하여, 해석대상과 성형조건, 그리고 가공재에 작용하는 자기압력은 Suzuki의 것과 동 일한 것을 사용하였다.

• 대한조선학회 특별논문집
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• 대한조선학회 2011년도 특별논문집
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• pp.32-35
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• 2011

Template has been widely used for hull forming process in most of shipyards. It is used to estimate the curvature of deformed shape in comparison with design shape. SHI (Samsung Heavy Industry) had used AutoKon system for ship manufacturing design in the past. The AutoKon used the global coordinate system of ship (frame, water line and so on) to create template data. It brought the mismatched angles between templates and a curved shell plate. The mismatched angle is measured by forming worker to place template on shell forming stage. However, the mismatched angle is difficult to place template with exactly required angle because the shell plates have various curvature and size. It causes incorrect shape of formed shell plates. The attached angle of template should be 90 degree to place template easily on forming shell plates. Currently, SHI has been applied GSCAD for ship manufacturing design process which is 3D solid modeling system. The GSCAD is the rule-based system which can automate 3D modeling and control the manufacturing data by rule. The rule can easily provide methods to create and automate template object with regular attached angle in comparison with AutoKon system. Therefore, SHI developed new template rule which it can automatically create template object with regular attached angle in GSCAD.

• 한국기계가공학회지
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• 제16권6호
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• pp.87-94
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• 2017

Hot stamping processes are possible for tensile strength 1.4 GPa but the strength reduction is appeared from the cooling performance unbalance. And the strength of roll forming process is below than that of hot stamping process owing to using the steel which is lower strength of boron steel. In this study, We provide roll forming process asssisted high-frequency induction heating to solve the problem of conventional one. The experiments were carried out at under various sill side part conditions: high-frequency induction heating conditions of 15, 18, 21, 24, 27 and 30 kW. The high-frequency induction heating temperature was checked with Infrared camera and the sill side parts of mechanical properties and microstructure were measured. The heating temperature of high frequency induction was measured to max $850^{\circ}C$ under the coil power of 30 kW. The tensile strength was 1.5 GPa and hardness was 490 Hv. The martensite structure was discovered under coil power of 30 kW. The weight of steel material sill side having thickness 1.5 mm and the boron steel sill side having thickness 1.2 mm were compared to weight effect. The boron steel sill side reduced 11.5% compared to steel. Consequently, manufacturing process of 1.5 giga-grade's sill side part was successfully realized by the roll forming assisted high-frequency induction heating methods.

• 대한기계학회논문집A
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• 제35권9호
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• pp.1027-1033
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• 2011

VCM 강판은 용융아연도금강판 위에 PET/PVC 코팅하여 가전제품의 외판 소재로 사용되고 있다. 본 연구에서는 VCM 강판의 프레스 성형 중 발생하는 PET 코팅층의 찢김을 저감하기 위해 프레스 성형공정변수를 재설계하였다. 프레스 공정변수들이 PET 코팅층의 찢김에 미치는 영향을 분석하기 위해 유한요소해석을 수행하였다. PET 코팅의 찢김 현상은 드로잉 성형시 제품의 코너부 소재두께의 증가로 인해 금형과 소재 사이의 과도한 마찰에 의해 발생한다. 이를 해결하기 위해 블랭크 형상의 변경을 통해 드로잉성형시 코너부의 소재두께 증가를 저감하였으며, 트리밍 공정시 플랜지부의 과도한 두께 증가부분을 제거하여 플랜지 성형시 소재두께가 금형간극 이하로 분포하도록 하였다. 또한 성형실험과 유한요소해석을 통해 재설계된 공정변수들을 검증하였다. 이를 통해 PET 코팅의 찢김이 없는 양호한 최종제품의 성형이 가능함을 확인하였다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2000년도 추계학술대회 논문집
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• pp.316-321
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• 2000

Die Casting is one of the forming methods to manufacture large number of products with short period time and clean surface by high forming pressure and temperature of cast alloy. Die design is composed of selection of cast alloy, design of die casting product, runner and gate design etc. In reality, however, die design of die casting has been performed by trial and error method, which cause economic and time loss. This paper describes a research work of developing computer-aided design of die casting product and die design. Approach to the CAD system has been written in AutoLISP on the AutoCAD with personal computer. In this study, die design system for gate of die casting process has been developed to present algorithm for automation of die design, especially runner-gate system. As forming process and die design system using 3-D geometry handling are integrated with technology of process planning, die design is possible to set. In addition, specific rules and equations for the runner-gate system have been presented to avoid too many trails and errors with expensive equipment. It is possible for engineers to make automatic and efficient die design of die casting and it will result in reduction of expense and time to be required. An example is applied to cap-shaped casting using proposed algorithm.

• Clinical and Experimental Pediatrics
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• 제48권8호
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• pp.894-900
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• 2005

목 적 : 조직적합 항원의 불일치로 인하여 골수이식을 할 수 없는 경우에 점점 더 제대혈이 사용되고 있다. 그러나 제대혈의 조혈모세포의 수가 적기 때문에 이를 증가시킬 대책이 필요한 바, 여러 성장인자를 조합하여 체외증폭하여 말초혈의 체외증폭과 비교하였다. 방 법 : 저자들은 제대혈 및 말초혈로부터 분리한 CD34+ 세포를 혈청이 아닌 배양체에서 체외 증폭하여 비교하였다. Miltenyi 방법으로 분리한 CD34+는 조혈성장인자들과 함께 체외 증폭 시켰다. 증폭 당일, 4일 후, 7일 후 및 14일에 증폭된 세포를 가지고 burst-forming units of erythrocytes (BFU-E), colony-forming units of granulocytes and monocytes (CFU-GM) 및 colony-forming units of megakaryocytes (CFU-Mk)의 생성 능력을 알아보았다. 결 과 : 말초혈에 비하여 제대혈로부터 분리한 CD34+ 세포의 증폭 능력이 2배로 컸다. 체외에서7일 및 14일 동안 증폭된 제대혈이 더 많은 BFU-E를 생성하였고, 4일 및 7일 동안 증폭된 제대혈이 더 많은 CFU-Mk를 생성하였다. 결 론 : MGDF, FL 및 IL-3를 포함한 성장인자의 자극 하에서 제대혈의 체외 증폭이 더 많은 BFU-E 및 CFU-Mk를 생성하였으므로, 이를 이용한 체외 증폭을 시도하는 것의 가능성을 시사하고 있다.

• Journal of Computational Design and Engineering
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• 제1권3호
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• pp.187-193
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• 2014

One of the hottest challenges in automotive industry is related to weight reduction in sheet metal forming processes, in order to produce a high quality metal part with minimal material cost. Stamping is the most widely used sheet metal forming process; but its implementation comes with several fabrication flaws such as springback and failure. A global and simple approach to circumvent these unwanted process drawbacks consists in optimizing the initial blank shape with innovative methods. The aim of this paper is to introduce an efficient methodology to deal with complex, computationally expensive multicriteria optimization problems. Our approach is based on the combination of methods to capture the Pareto Front, approximate criteria (to save computational costs) and global optimizers. To illustrate the efficiency, we consider the stamping of an industrial workpiece as test-case. Our approach is applied to the springback and failure criteria. To optimize these two criteria, a global optimization algorithm was chosen. It is the Simulated Annealing algorithm hybridized with the Simultaneous Perturbation Stochastic Approximation in order to gain in time and in precision. The multicriteria problems amounts to the capture of the Pareto Front associated to the two criteria. Normal Boundary Intersection and Normalized Normal Constraint Method are considered for generating a set of Pareto-optimal solutions with the characteristic of uniform distribution of front points. The computational results are compared to those obtained with the well-known Non-dominated Sorting Genetic Algorithm II. The results show that our proposed approach is efficient to deal with the multicriteria shape optimization of highly non-linear mechanical systems.

• 한국정밀공학회지
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• 제19권6호
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• pp.176-183
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• 2002

Plasma Display Panel(PDP) is a type of flat panel display utilizing the light emission produced by gas discharge. Barrier Ribs of PDP separating each sub-pixel prevents optical and electrical crosstalks from adjacent sub-pixels. The mold for forming the barrier ribs has been newly researched to overcome the disadvantages of conventional manufacturing processes such as screen printing, sand-blasting and photosensitive glass methods. The mold for PDP barrier ribs have stripes of micro grooves transferring glass-material wall. In this paper , Stripes of grooves of which width 48$\mu$m, depth 124$\mu$m , pitch 274$\mu$m was acquired by machining of single crystal silicon with dicing saw blade. Maximum roughness of the bottom of the grooves was 59.6 nm Ra in grooving Si. Barrier ribs were farmed with silicone rubber mold, which is transferred from grooved Si forming hard mold. Silicone rubber mold has the elasticity, which enable to accommodate the waviness of lower glass plate of PDP. The methods assisted by the microwave and UV was adopted for reducing the forming time of glass paste.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2008년도 춘계학술대회 논문집
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• pp.829-830
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• 2008