• 대한기계학회논문집A
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• 제28권11호
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• pp.1703-1710
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• 2004

The objective of this investigation is to formulate and carry out the topology optimization of a magnetic system consisting of permanent magnets and yokes. Earlier investigations on magnetic field topology optimization have been limited on the design optimization of yokes or permanent magnets alone. After giving the motivation for the simultaneous design of permanent magnets and yokes, we develop the topology optimization formulation of the coupled system by extending the technique used in structural problems. In the present development, we will also examine the effects of the functional form for permeability penalization on the optimized topology.

• 보건행정학회지
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• 제2권2호
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• pp.179-193
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• 1992

This paper attempts to explain why the prescribing-dispensing services are not seperated in Korea. The main reason why physicians and pharmacists do not compromise, even though the two parties support the seperation policy in public, is contended to be that both parties would lose their interests if the policy were implemented. Physicians' loss from giving up their vested rights to dispensing would be larger than their gain from an increase in the number of prescriptions. Pharmacists' loww from being forced not to to sell medicines without prescriptions would also be larger than their gain from prohibiting physicians from dispensing. The net ganier form the seperation policy would be the patients. Therefore, the seperation policy would not be implemented unless political pressure from general public surpasses that from physicians and pharmacists.

• Bulletin of the Korean Chemical Society
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• 제8권6호
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• pp.444-449
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• 1987

Solvent effects on gas phase reactions of methoxide ion with substituted ethylenes, $CH_2$ = CHR where R = CN, CHO and $NO_2$, are investigated theoretically using the AM1 method. Results show that the methoxide approaches in-plane in all reactions, but subsequently rotate out-of-plane to form tetrahedral complexes in additon reactions. All reactions of a bare methoxide are found to be exothermic, the exothermicity being the greatest in the ${\beta}$-addition, in which the excess energy is forced to be contained within the ${\beta}$-adduct rendering extreme instability. However a part of the excess energy can be removed by a solvate molecule giving a stable complex prior to the product formation. The hydride transfer processes were found to be unfavorable due to the high activation barriers. The ${\alpha}-H^+$ abstraction process from acrylonitrile becomes endothermic as a result of monosolvation of the methoxide, in agreement with experimental results.

• 천문학회보
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• 제44권2호
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• pp.60.3-60.3
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• 2019

Binary systems of a white dwarf showing mass transfer activities are classified into cataclysmic variables and symbiotic stars. In the case of cataclysmic variables, the companion is usually a late type main sequence star filling its Roche lobe, where material is transferred through the inner Lagrangian point to form an accretion disk around the white dwarf. The disk becomes unstable and highly viscous when the surface density exceeds the critical density, leading to dwarf nova outbursts. In contrast, symbiotic stars are wide binary systems having a giant as the mass donor. Some fraction of giant stellar wind is accreted to the white dwarf giving rise to various symbiotic activities. In particular, half of symbiotics show Raman O VI at 6830 and 7088, which are important spectroscopic probe of mass transfer process. Monitoring observations using 1 m class telescopes will produce valuable information regarding the mass loss and mass transfer to white dwarf stars, shedding much light on the last stage of stellar evolution of low and intermediate mass stars.

• BMB Reports
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• 제57권5호
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• pp.216-231
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• 2024

Mammalian genomes are intricately compacted to form sophisticated 3-dimensional structures within the tiny nucleus, so called 3D genome folding. Despite their shapes reminiscent of an entangled yarn, the rapid development of molecular and next-generation sequencing technologies (NGS) has revealed that mammalian genomes are highly organized in a hierarchical order that delicately affects transcription activities. An increasing amount of evidence suggests that 3D genome folding is implicated in diseases, giving us a clue on how to identify novel therapeutic approaches. In this review, we will study what 3D genome folding means in epigenetics, what types of 3D genome structures there are, how they are formed, and how the technologies have developed to explore them. We will also discuss the pathological implications of 3D genome folding. Finally, we will discuss how to leverage 3D genome folding and engineering for future studies.

• 한국환경보건학회지
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• 제46권4호
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• pp.410-422
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• 2020

Objectives: According to the Act on Registration, Evaluation, Etc. of Chemicals, new and existing chemicals must be registered by 2030. In addition, industries need to submit hazard data as an attachment during the registration process. Therefore, we constructed a nationwide chemical database to support small industry by providing hazard data and original sources. During the process, we developed a new standard procedure for minimizing errors and increasing reliability. Methods: We analyzed the categories of errors and the cause of the errors through the verification results of the 2019 project. We present an improved database construction methodology and system. Results: Errors are categorized according to their causative factors into simple, technical, and structural type errors. Simple errors arise simply because of decreased concentration or negligence in following the instructions. Technical errors are caused by a discrepancy between the professional field and the type of data. Structural errors indicate systemic errors such as incomplete forms on the excel database or ambiguity in the guidelines. Lessons from the errors collected in the 2019 project are used to update the procedures for database authorization and technical guidelines. The main update points are as follows; 'supplementation of review process', 'giving regular training to external reviewers', 'giving additional information to authors, like physico-chemical properties of substances, degradability, etc.', 'amendment of excel form', and 'guideline upgrades'. Conclusions: We conducted this study with the aim of improving the accuracy and reliability of the database of hazard information for chemical substances. The new procedures and guidelines are now being used in the 2020 project for construction of a hazard information database for Korea.

• The International Journal of Costume Culture
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• 제3권3호
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• pp.212-222
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• 2000

This study intends to observe how the essential elements of art have changed Human's sense of beauty extending over the whole lives as well as fashion through the investigation of Light and Rays which have played a important role in giving birthe to the new trend of art within the upheaval age of various cultures. The peculiarities of which Futurism of Italy and Rayonism of Russia including Impressionism have a great role in giving birth to a new trend of art by means of the development of science technology are like these. Impressionists looked for the origin of the subtle harmony in nature within changes of sun-rays. The special feature of Impressionism paintings was to express the line of vision diversely according to changes of light rather than to focus on the line of vision with clear outlines. Henceforth, Neo-Impressionism which developed Impressionism more systematically leaded changes of Light and Rays more systematically and scientifically and maintained Divisionnisme techniques which extends to lead towards color and light through dividing and juxtaposing color. In the early 20th century Futurists tried to express dynamism through the interpenetration of light and revive color and light through the division techniques of color and persist an artificial light like eletricity rather than a natural light. Rayonism of Russia which was ifluenced from Impressionism and Futurism maintained intersection of reflecting rays which emerges from an object of things more deeply. This pursuit of light and rays also light and rays also appears as it is in modern fashion. First, it is the fashion which applied sun-rays persisted by Impressionists and expressed colors which show differently according to direction of light. Second, it is the fashion design which re-analyzed what Futurists expressed artificial light and rays. Third, it is the design which expressed Divisionnisme theory persisted by Impressionists and Futurists into fashion as it is and was made of being divided the form of glittering light into small dots. Fourth, it is the fashion design which applied Rayonists'work which applied intersection of reflected rays. Like this, it is aproved that the pursuit of light and rays expresses as it is in modern fashion of the 21st.

• 한국게임학회 논문지
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• 제6권3호
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• pp.43-50
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• 2006

본 연구는 초등학교 수학과 수 연산 영역에서의 수준별 학습을 지원하기 위한 게임형 학습 프로그램을 개발하는 것이다. 수학과는 위계성이 강한 단계형 교과로 학습자 개개인의 수준을 고려한 수준별 학습이 꼭 필요한 교과이다. 그러나 일선 학교에서는 다인수 학급 및 보충지도 시간 부족 등으로 인하여 학습자 수준에 맞는 개별적인 수준별 학습이 잘 이루어지기 않고 있는 실정이다. 따라서, 본 연구는 수준별 개별화 학습을 지원하여 올바른 수와 연산개념의 형성을 위한 게임형 학습 프로그램을 개발한다. 본 학습 프로그램은 학습자의 학습 진척도와 성취도를 검사하여, 학습자에게 맞는 학습 단계를 자동으로 조절해 준다. 그리고 학습 중에도 학습자의 수준을 고려한 힌트와 구체물 조작을 통해 문제를 해결할 수 있도록 도움 기능을 제공한다. 본 학습 프로그램을 학습자들에게 적용한 결과 수학과 학습에 대한 흥미도를 높아지고 특히, 힌트 및 도우미 기능은 문제 해결에 도움이 되는 것으로 나타났다.

• 한국의류산업학회지
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• 제5권1호
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• pp.17-24
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• 2003

Objet, which showed up with the art of 20C, is now an important element giving a creative idea to fashion designers in modern times. The purpose of the study is to review how the objet technique was paid attention and recreated in the fashion, through the analysis of works, and the formative features of each technique for fashion, in order to identify the connection of arts and fashion, and the position of fashion as art. The techniques using object appeared in the 20th century fashion are as follows: First, papier-colle, which is adding printed materials onto the surface, is such a technique that adds cut-feeling materials to impose a new texture, or arrange again the cloth-cuts to create a different clothing from the existing one, which went to the extension of materials in the fashion. Second, collage of daily materials expresses directly and emotionally through direct presentation of the objets. Especially, collage of patch-work is reproduced into a new fabric depending on the objet used, giving a standing over the form. Third, ready-made which presents the material meaning only of the objet expands the range of objets which could be used in the fashion by introducing the daily materials having a meaning itself as a fashion. Forth, an attempt to approach to the objets of popular image by designed techniques come out in modern fashion as a graffiti look or a typography look, making the clothing itself an objet to transmit a message directly to the masses. Introduction of various objets and development of expression technique brought out the diversification of materials, and enrichment and extension of expression sphere, which resultingly spreaded the freedom of expression and progressed into the art sphere, making a direct motif to solidify its standing as a formative art.

• 벤처혁신연구
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• 제3권2호
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• pp.177-195
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• 2020

세계가 점점 더 통합됨에 따라 자선단체는 국내 문제 뿐만 아니라 빈곤, 기근, 자연 재해 등 세계 전역에서 일어나는 문제들을 다루게 되었다. 국제적으로 많은 조직들이 도움을 제공하고 이러한 문제들을 완화시키기 위해 노력하고 있지만, Jusoor, Karam Foundation, Save the Children, 그리고 Oxfam 등 대부분의 자선단체들이 서구사회에 기초하고 있다. 이 논문은 동양과 서양 두 지역 사이에 기부 문화 불균형이 존재하는 이유를 분석한다. 이 논문은 지역적 차이를 설명하면서 자선 재단에 대한 아시아인들의 뿌리 깊은 불신과 아시아에서의 자선 기부를 장려하는 정부 정책의 부재, 그리고 추세를 형성하는 다른 여러 사회적, 경제적, 정치적 요인에 특히 초점을 맞추고 있다. 아시아가 세계의 다른 지역에 비해 자선 문화에서 왜, 그리고 얼마나 크게 뒤처지는지를 분석한 결과, 이 논문은 아시아 자선 시장에 "창조적 파괴"가 필요하다는 것을 증명한다. 더 나아가 이 논문은 혁신적인 신생 기업이 새로운 형태의 기술, 즉 등록 파트너쉽 기반을 갖춘 접근하기 쉬운 애플리케이션을 도입하여 정기적으로 앱 사용자들의 기부금 사용처와 금액을 업데이트함으로써 아시아 자선 사업의 신뢰도를 높일 수 있다고 제안한다. 이러한 새로운 형태의 기술은 아시아의 자선 문화를 둘러싼 다른 문제들을 다루는 데 또한 도움이 될 것이다.