• Journal of applied mathematics & informatics
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• 제13권1_2호
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• pp.53-65
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• 2003

Here we present a study of small-amplitude, shallow water waves on sloping beds. The beds considered in this analysis are linear and quadratic in nature. First we start with stating the relevant governing equations and boundary conditions for the theory of water waves. Once the complete prescription of the water-wave problem is available based on some assumptions (like inviscid, irrotational flow), we normalize it by introducing a suitable set of non-dimensional variables and then we scale the variables with respect to the amplitude parameter. This helps us to characterize the various types of approximation. In the process, a summary of equations that represent different approximations of the water-wave problem is stated. All the relevant equations are presented in rectangular Cartesian coordinates. Then we derive the equations and boundary conditions for small-amplitude and shallow water waves. Two specific types of bed are considered for our calculations. One is a bed with constant slope and the other bed has a quadratic form of surface. These are solved by using separation of variables method.

• 한방안이비인후피부과학회지
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• 제10권1호
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• pp.284-305
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• 1997

A Literatural study on the etiological factors, classification, prescription of hemorrhoids and hemorrhoids complicated by anal fistula following results were obtained. 1. The cause of hemorrhoids are long time sit, long time gate, overfatigue, overeating, imbalance of stool( constipation or diarrhea), pregnant fertility(overfatigue after childbirth, insufficiency of middle warmer energy), uncontrol sexual excess, pathgenic factors of wetness, heat, wind, dry, genetic cause, excess of anxiety, pile up of heat poison, weakness of entrails and viscera. The cause of hemorrhoid complicated by anal fistula are attack of external wind, heatness, dry, fire, wetness(pathgenic factors), inapporiate treatment and chronic disease, greasy diet, excess of anxiety, constipation, uncontrol sexual excess, obstacle of circulation of vital energy and blood on anal site. 2. Classification of hemorrhoids are female hemorrhoids, male hemorrhoids, pulse hemorrhoids, intestines hemorrhoids, vital energy hemorrhoids, wine hemorrhoids, blood hemonhoids, flowing hemorrhoids. Classification with other method are external hemorrhoids, internal hemorrhoids, mixed hemorrhoids, excrescence hemorrhoids, nipple homorrhoids. External hemorrhoids is classified of varicosis of hemorrhoidal vein, connective tissue form, thrombus form. Classification of hemorrhoid complicated by anal fistula are simple lower hemorrhoid, lower mixed hemorrhoid, deep hemorrhoid, outer of one hole hemorrhoid, a horseshoe hemorrhoids. Once more classificated of four are space of sphincter muscle form, penetration sphincter muscle form, upper of sphincter muscle form, outer of sphincter muscle form. 3. Therapy method of hermorrhoid and hemorrhoid complicated by anal fistula are internal method, fumigation method method, ointment, method of close with medicine, necrotizing method, hot medicated compress( gxternal method), injection, insertion, bind, (operation) and acupuncture therapy (the others method) 4. Herb medicine for many used of internal method are Scutellaria baikalensis George(黃芩), Coptis japonia Makino(黃連), Rehmania giutinosa Liboschitz ex Fischer & Meyer(生地黃), Poncirus trifoliata Refinesque(枳殼), Sanguisorba officinalis Linne(地楡), Sophora japonica L.(槐花), Cnidium officinale Makino (川芎), Astragalus membranaceus Bunge(황기), Angelica gigas Nakai (當歸). 5. Herb medicine for many used of fumigation are Schlechtendalia Chinesis J. Bell (五倍子), Artemisia Vulgaris L. var indica Maxim(艾葉), Poncirus trifoliata Refinesque (枳殼), Nepeta japonica Maximowicy(荊芥), And herb medicine for many used of ointment are Calomelas(輕粉), Alum(白礬), Boswellia carterii Birdwood(乳香), Os Draconis Fossilia Ossis Mastodi(龍骨).

• 대한한의학방제학회지
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• 제16권2호
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• pp.11-29
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• 2008

Objective : The aim of this study was to analyse the latest trend of medical science articles about Bojungikki-Tang published in Japan. Methods : We searched medical science articles published from 2003 to 2008 in Japan on the web site, CiNii and then these articles were reviewed and classified according to experimental subject and method. Results : Fifty-two articles, related to Bojungikki-Tang were searched and these were classified into three classes, pharmacological signaling studies, clinical case studies and the others. As a result of classification, clinical case studies were most abundant by 38 cases, pharmacological signaling studies were 10 and the others were 4. This result suggested that the study of Bojungikki-Tang was mainly focused on clinical study rather than experimental study. Among the clinical case studies, clinical studies related to immune disease took the most greatest number and number of other clinical studies were evenly distributed over the various disease. Immune intensification effect of Bojungikki-Tang can be thought continuous with reinforce the middle Jiao Qi in company with improvement effect on growth hormone failure and male infertility. A fact that the one prescription, Bojungikki-Tang could be used to treat various diseases reflects a viewpoint of Oriental medicine that is based on the respect for and understanding of individual constitution and disposition while paying attention to the gender difference and individuality. The clinical usefulness of Bojungikki-Tang on obstructive sleep apnea syndrome and visceroptosis concerns with ascend Yang and treat Qi sinking. Pharmacological signaling studies were mainly focused on diseases that were treated Bojungikki-Tang in clinic, however, there was one study that experimented on changes of numerous gene expression according to the treatment of Bojungikki-Tang using DNA array. Conclusion : The therapeutic system of Oriental medicine is different in various aspects form that of Western medicine and appropriate harmonization of east and west is expected to improve the quality of medical care. In this regard, continuous investigation and analysis about herbal medical science papers in Japan can also be useful to make progress in Korean traditional medicine.

• Journal of Pharmaceutical Investigation
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• 제34권4호
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• pp.299-303
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• 2004

Prescription filling in powder form is performed in community pharmacy practice to adjust dose for children and patients who cannot swallow whole tablet. However, there are few reports regarding the stability of the active ingredient and possible microbial growth after the medication is dispensed to powder form. This study examined the stability of atenolol, an antihypertensive agent, and microbial growth in the unit dose pouches dispensed at twenty-one community pharmacies located in Taegu area. Randomly chosen first unit dose pouch contained 77.4% of the prescribed dose of the drug and there were only four community pharmacies that dispensed the drug within 10% deviation from the dose prescribed by physician. Surprisingly, there were three community pharmacies that dispensed the drug with greater than 40% deviation, which may pose a major concern regarding the efficacy and safety of the drug prescribed for the treatment of hypertension. Atenolol content during a month did not indicate significant change, showing 5.4%, 4.3%, and 3.3% of decrease in 50%, 80%, and 90% relative humidity conditions, respectively. Microbiological examination during a month showed less than 0.5 microorganism in high power field (hpf) in all the relative humidity conditions tested. Based on this study, pharmacy practice in community pharmacy needs to be rigorously regulated to ensure that the dose of the prescribed drug is properly incorporated into the unit dose pouch dispensed as powder form.

• 대한상한금궤의학회지
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• 제5권1호
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• pp.101-111
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• 2013

Objective : The purpose of this study is to find out the proper dosage of Ma-huang for clinical use of Shanghanlun(傷寒論) Methods : To achive the purpose of this study, web-databases(pubmed, naver, google) were searched with the keywords including 'dose of Ma-huang Ephedra Ephedrine','dosage of Ma-huang Ephedra Ephedrine', and 'water extract of Ma-huang Ephedra'. The searched 30 papers and articles were reviewed. Results & Conclusions : 1. Proper dosage of Ma-huang 1) Adult: up to 9-12g/day 2) Adolescent: up to 6g/day 3) Hypertension disorder patient: up to 6g/day 4) lactating women: up to 6g/day 5) child: <2 years 0.7-2.5g/day, $${\geq_-}2$$ years 2.6-6g/day (Different from body weight) Although administration of Ma-huang to hypertension disorder patient, lactating women, child is safe on the paper, It is not recommended to these people because Ma-huang is one of toxic herbs. 2. Dosage form of Ma-huang There's no safety paper about pill or powdered Ma-huang(麻黃). There's not pill or powdered prescription of Ma-hunag in Shanghanlun(傷寒論), either. So it is recommended to administrate water exetract of Ma-huang.

• Journal of Microbiology and Biotechnology
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• 제25권10호
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• pp.1653-1659
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• 2015

Epothilone, which is produced by the myxobacterium Sorangium cellulosum, contributes significant value in medicinal development. However, under submerged culture conditions, S. cellulosum will accumulate to form bacterial clumps, which hinder nutrient and metabolite transportation. Therefore, the production of epothilone by liquid fermentation is limited. In this study, diatomite-based porous ceramics were made from diatomite, paraffin, and poremaking agent (saw dust). Appropriate methods to modify the porous ceramics were also identified. After optimizing the preparation and modification conditions, we determined the optimal prescription to prepare high-performance porous ceramics. The structure of porous ceramics can provide a solid surface area where S. cellulosum can grow and metabolize to prevent the formation of bacterial clumps. S. cellulosum cells that do not form clumps will change their erratic metabolic behavior under submerged culture conditions. As a result, the unstable production of epothilone by this strain can be changed in the fermentation process, and the purpose of increasing epothilone production can be achieved. After 8 days of fermentation under optimized conditions, the epothilone yield reached 90.2 mg/l, which was increased four times compared with the fermentation without porous ceramics.

• 대한한의학회지
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• 제21권2호
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• pp.3-13
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• 2000

Objectives : In oriental medicine, Daeseungki-tang is one of the most useful prescriptions for the therapy of constipation. And we also frequently use this prescription for constipated stroke patients. Methods : In order to identify the effects of Daeseungki-tang on constipated stroke patients, we administrated the extract of Daeseungki-tang(code number, HH264) to constipated stroke patients. We gave the medicine in two ways, one-pack group and two-pack group by random allocation and investigated the amount of stool, the frequency of defecation, the stool-form and the changes of blood pressure and body temperature before and after defecation. We also tried to examine the difference of symptoms between defecation-group and non-defecation group. Results : 1. There were no distinct symptoms between defecation-group and non-defecation-group in one-pack group. 2. After defecation, body temperature decreased significantly(P<0.05) in one-pack group and blood pressure decreased significantly(P<0.05) in two-pack group. 3. As for the stool-form, watery-soft was 41.9% in the firstt defecation and 47.1 % in the second defecation. 4. In one-pack group(23 cases), 13 cases(57%) defecated and 10 cases(43%) didn't defecate. And in two-pack group(24 cases), 19 cases(80%) defecated and 5 cases(20%) didn't defecate. These results meant that the effect of Daeseungki-tang was dose dependent. The amount of stool and the frequency of defecation were also dose dependent.

• 한국의사학회지
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• 제25권1호
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• pp.71-79
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• 2012

Present Saam acupuncture can be divided into two types of Therapeutic part that is composed of physiology, pathology, classification of the symptoms, treatment and Experiential part that is composed of clinical case. Therapeutic part is authored by Saam and experiential part is authored by Ji-san. Experiential part is based on therapeutic part, but it has been changed. So, Measuring "chapter10. Saam acupuncture(apply to therapeutic part)" against "chapter11. Clinical case of Ji-san(apply to experiential part)", Author get to know that experiential part of Saam acupuncture has been changed. "chapter10. Saam acupuncture(apply to therapeutic part)" and "chapter11. Clinical case of Ji-san(apply to experiential part)" belong to "TaeHanUiHakJeonJip Acupuncture part" that is similar to manuscript of Saam acupuncture. The following is changed situation of Saam acupuncture. First, While the theory of Jeong form is already established in therapeutic part, the theory of Seung form is established in experiential part. So, In experiential part, they are equal in their relations. Second, In experiential part, the term that is named 'prescription of ${\bigcirc}{\bigcirc}$' has been used since experiential part. Third, Some of spots on the body suitable for acupuncture mentioned in therapeutic part are omitted in experiential part. And to conclude, experiential part play a large role in the establishment and change of early Saam acupuncture.

• 한국의사학회지
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• 제18권2호
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• pp.245-255
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• 2005

The researcher categorized the acupuncture methods mentioned in DongUiBoGam according to the form, and examined how to select and use the acupuncture points explained in the Acupuncture/Moxibustion prescription. By comparing the original text to the Acupuncture/Moxibustion prescriptions, it was established that the various acupuncture points in these Acupuncture/Moxibustion prescriptions all had individual meaning. Also, it showed that DongUiBoGam didn't indicate a particular acupuncture point but allowed a possibility for selection according to the patient's condition and the skill of the practitioner.

• 대한한방내과학회지
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• 제24권2_4호
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• pp.1075-1079
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• 2003

BacJung-pil(百中丸) using in stagnation-syndrome of gi and blood(痺證) is a expience prescription, A female patient diagnosed as wind syndrome of head(頭風), and stagnation-syndrome of gi and blood(痺證) showed severe pruritus, rash and eruption of skin. After the patient took BackJun-Pill, two hours later, We examined her change and witnessed macular papule and severe pruritus. Those symptoms disappeared in 7 days since we administer anti-histamine, steroid and GamDu-TangGamiBang(甘豆湯加味方).