• 한국임상수의학회지
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• 제27권4호
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• pp.457-461
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• 2010

Three dogs were presented with signs of recurrence of coughing, dyspnea and difficulty of barking after endotracheal stent placement. On the basis of history taking, physical examination, laboratory tests and radiography, complications of endotracheal stent were suspected. Dog 1 had unfitted stent diameter (stent diameter is larger than tracheal diameter) and getting disentangled of proximal tracheal stent wire. Dog 2 was suspected a foreign body reaction. Dog 3 had the migration of stent caudally. Based on these cases, the veterinarian should accurately evaluate the indicated patients before endotracheal stent and has to select the appropriate stent (diameter, length and location) to prevent complications after endotracheal stent and concern the regular follow-ups to assure proper endotracheal stent placement.

• Archives of Reconstructive Microsurgery
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• 제24권1호
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• pp.16-19
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• 2015

The authors had five cases of penoplasty from more than half of the scrotum to the suprapubic region using a fasciocutaneous radial forearm free flap (RFFF) after extensive excision of sclerosing lipogranuloma. Although the harvested RFFF was a rectangular shape, the authors made the shape of scrotum, penile shaft, and suprapubic region by using well designed geometry and several quilting sutures on junction of scrotum and penis. The contour of scrotum and penis was well maintained, and there were no complications, such as scrotal contracture, penile deformity, and erectile dysfunction during the one year follow up period in all five cases. There were no recurrent lesions and no need for further surgery.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.28.1-28.4
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• 2020

Background: This clinical case presented a novel method of segmental mandible reconstruction using 3D-printed titanium implant with pre-mounted dental implants that was planned to rehabilitate occlusion. Case presentation: A 53-year-old male who suffered osteoradionecrosis due to the radiation after squamous cell carcinoma resection. The 3D-printed titanium implant with pre-mounted dental implant fixtures was simulated and fabricated with selective laser melting method. The implant was successfully inserted, and the discontinuous mandible defect was rehabilitated without postoperative infection or foreign body reaction during follow-ups, until a year. Conclusions: The 3D-printed titanium implant would be the one of the suitable treatment modalities for mandible reconstruction considering all the aspect of mandibular functions.

• 대한영상의학회지
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• 제81권5호
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• pp.1255-1259
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• 2020

음낭 내에 발생한 경화지방육아종은 매우 드문 질환으로 지방조직의 이물반응에 의해 발생하는 것으로 알려져 있다. 주로 음경 및 음경음낭이음부에 발생한 임상적 보고 및 음낭 내 발생한 초음파 소견에 대한 증례 보고는 있었지만 저자들이 아는 한도에서는, 음낭 내 경화지방육아종의 자기공명영상 소견에 대하여 자세히 보고된 바는 없었고, 특히나 영문으로는 본 저자들이 탈장성형술 후 발생한 음낭 내 감염성 경화지방육아종에 대해 처음 보고하는 바이다.

• Journal of Periodontal and Implant Science
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• 제25권2호
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• pp.301-320
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• 1995

The purpose of this study was to evaluate a new biodegradable membrane - atelocollagen as a guided tissue regeneration barrier on the dehiscence defects adjacent to the dental implants. 3 beagle dogs were selected for this study and all the mandibular premolars($P_1,P_2,P_3&P_4$) were extracted. Twelve weeks after the extraction, the edentulous ridges were formed to be placed the titanium plasma-sprayed IMZ implants. Four implant osteotomies were performed on each side of the mandible. The osteotomies were placed facially in the edentulous ridges to approximate an actual dehiscence defect as closely as possible, The standardized dehiscence defects were created 3 mm in width and 4 mm in height by osteotomy. A total 24 implants were placed. e-PTFE, ateloco11agen and $Collatape^{(R)}$ were placed to cover the defects and the one defect served as a control, not covered any membrane. By random selection, three dogs were sacrificed at 2 weeks, 4weeks and 8 weeks after fixation with 3% glutaraldehyde. A week before sacrificing, 8-week dog was infused intravenously with oxy-tetracycline 30mg/kg. The left mandibular blocks were used for full decalcified histologic preparation and the right mandibular blocks were selected for undeca1cified preparation, At 2 weeks, the regenerated bone of e-PTFE and atelocollagen groups appeared to be more dense than other groups and the percentage of bone defect fill was highest for e-PTFE and follwed by ateloco1lagen group. However, the $Collatape^{(R)}$ and control groups showed a little new bone formation. $Collatape^{(R)}$ was almost degraded within 2 weeks. At 4 weeks, the regenerated new bone were much greater and denser than at 2 weeks for e-PTFE and ateloco11agen group. Although a part of atelocollagen bagan to be degraded at the margin and surrounded by foreign body giant cells related to foreign body reaction, it was generally intact and the regenerated new bone was shown much more than at 2 weeks. The amount of new bone in $Collatape^{(R)}$ and control groups at 4 weeks were similar to that of 2 weeks group. At 8 weeks, the regenerated bone was matured and observed along the implant fixture. Direct new bone formation and calcium deposits beneath the e-PTFE were observed. No further bone growth was seen in the $Collatape^{(R)}$ and control groups. In reflected fluoromicrcocopic observation, the osteogenic activity was pronounced between e-PTFE membrane and the old bone. High osteogenic activity was also observed in atelocol1agen group. This study suggested that the ateloco11agen as well as e-PTFE could be used for guided tissue regeneration on dehiscence defects adjacent to the dental implants. But the $Collatape^{(R)}$ was completely resorbed within 2 weeks and was not a suitable membrane for guided bone regeneration.

• 한국산학기술학회논문지
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• 제14권1호
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• pp.229-238
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• 2013

본 연구는 대학 엘리트 카나디언 선수들의 등속성 근기능을 검사 및 진단하여 선수들의 기능 향상 및 상해예방을 위한 훈련 방법론에 대한 조언을 하고자 함에 목적이 있다. 경주 소재 D 대학의 평균 8.5년의 경력을 가진 8명의 엘리트 선수들이 실험에 참가했으며, Biodex system III, Biodex stabilizer system, THP 2, Inbody 720이 근기능 검사(peak torque, average power, work fatigue), 동적 균형 검사, 신체성분 검사를 위해 사용되었다. 등속성 근기능 검사는 어깨와 허리, 무릎 관절에 대하여 실시하였으며, 측정 후 동측 불균형과 좌 우측 불균형 정도를 평가하였다. 검사 결과 A3, A4, A5, A6, A8 선수는 어깨의 근력과 파워 훈련이, A1, A2, A7, A8 선수는 어깨의 근지구력 훈련이 필요한 것으로 평가되었다. A2, A5, A8 선수는 허리의 근력과 파워 강화 훈련이 필요하였고, A1, A8 선수는 허리의 근지구력 강화 훈련이 필요하였다. 대부분의 선수들은 무릎과 허리의 동측 근력비가 정상적이지 못했는데, 이의 개선을 위해 A2, A3, A4, A8 선수는 복근의 강화가 필요했고 A3, A5, A6, A7, A8 선수는 햄스트링의 강화가 요구되었다. 선수들의 BMI 평균은 24.90 $kg/m^2$, 체지방율은 12.23%, 반응시간 평균은 324 msec, 밸런스 점수는 각각 2.0 미만으로 나타났다. 이러한 결과를 종합해 볼 때, 카나디언 엘리트 선수들은 근력 불균형에 의한 경기력 저하와 상해 잠재 위험성이 있으므로 정기적인 근기능 검사를 통한 관리와 함께 적절한 훈련 처방이 필요할 것이라 생각된다.

• 생명과학회지
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• 제21권9호
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• pp.1336-1345
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• 2011

본 연구에서는 국내외 실버화와 일반적인 운동화에 대한 1차 운동기능학적 분석을 통하여 노인에게 가장 적합한 신발을 정하고 2차 운동생리학적 실험을 통해 체지방률변화, 운동강도에 따른 대사량의 변화 그리고 에너지 소비량의 변화를 분석하였다. 본 연구의 대상으로는 특별한 질병을 가지고 있지 않은 남자 어른들 20명을 대상으로 하였으며, 평균나이는 $62.78{\pm}4.32$세, 신장은 $170.89{\pm}3.56cm$ 그리고 몸무게는 $75.12{\pm}8.76kg$이었다. 실험 전 실험에 대한 충분한 설명을 하고 동의서를 받은 후 데이터를 수집하였다. 본 연구를 위하여 운동 기능학적 실험과 운동 생리학적 실험을 수행하였으며, 본 연구결과 걷기나 달리기 시 최초 발 뒤꿈치 접촉 시 발이 회내(pronation)되는 정도와 최대 회내가 되는 정도를 알아 본 결과 걷기속도가 가장 빠르게 나온 B형의 신발이 회내값($-2.3{\pm}1.05^{\circ}$)이 가장 크게 나타났으며 일반걷기용 신발에서 가장 작은 값($-1.5{\pm}0.49^{\circ}$)을 보여주고 있다. 또한 노인들의 일상생활에서 착용하는 건강증진용 신발을 대상으로 운동 생리학적 부분을 살펴보면 체지방율의 변화는 모든 그룹에서 감소는 하였으나, 통계적으로 유의한 차이가 나타나지 않았는데, 이는 체지방율의 변화를 가져오기 위해서 일시적인 운동이 아닌 규칙적이고 장기적인 운동이 필요할 것으로 사료되어지며, 노인들이 건강증진용 기능화를 장기적으로 착용하여 운동할 경우 체 지방율에 긍정적인 영향을 미칠 것으로 사료되어진다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권1호
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• pp.1-11
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• 2012

Purpose: The purpose of this study was to evaluate the bone regeneration capacity of silk fibroin (SF) when combined with beta tricalcium phosphate (${\beta}$-tricalcium phosphate [TCP]) and rh-bone morphogenetic protein (BMP) in vivo by micro-computed tomography (CT), soft x-ray, and histological analysis. Methods: A total of 56 critical size defects formed by a trephine bur made on 28 adult female Spague-Dawley rats were used for this study and the defect size was 5.0 mm in diameter. The defects were transplanted with (1) no graft material (raw defect), (2) autogenous bone, (3) SF ($10{\mu}g$), (4) SF-BMP ($10{\mu}g$, $0.8{\mu}g$ each), and (5) SF+${\beta}$-TCP ($10{\mu}g$). At 4 and 8 weeks after operation, the experimental animals were sacrificed. Samples were evaluated with soft x-ray, histological examinations and 3-dimensional micro-CT analysis. Results: In the 3-dimensional micro-CT evaluation, bone volume and bone surface data were higher in the SF-BMP ($12.8{\pm}1.5$, $138.6{\pm}45.0$ each) (P<0.05) and SF-TCP ($12.3{\pm}1.5$, $144.9{\pm}30.9$ each) group than in the SF group ($6.1{\pm}3.3$, $77.2{\pm}37.3$ each) (P<0.05), except for the autogenous group ($15.0{\pm}3.0$, $190.7{\pm}41.4$ each) at 4 weeks. At 8 weeks, SF-BMP ($16.8{\pm}3.5$, $173.9{\pm}34.2$ each) still revealed higher (P<0.05) bone volum and surface, but SF-TCP ($11.3{\pm}1.5$, $1132.9{\pm}52.1$ each) (P=0.5, P=0.2) revealed the same or lower amount compared with the SF group ($13.8{\pm}2.7$, $127.5{\pm}44.8$ each). The % of bone area determined by radiodensity was higher in the SF-TCP ($31.4{\pm}9.1%$) and SF-BMP ($36.2{\pm}16.2%$) groups than in the SF ($19.0{\pm}10.4$) group at the period of 4 weeks. Also, in the histological evaluation, the SF-BMP group revealed lower inflammation reaction, lower foreign body reaction and higher bone healing than the SF group at postoperative 4 weeks and 8 weeks. The SF-TCP group revealed lower inflammation at 4 weeks, but accordingly, as the TCP membrane was absorbed, inflammatory and foreign body reaction are increased at 8 weeks. Conclusion: The current study provides evidence that the silk fibrin can be used as an effective grafted material for tissue engineering bone generation through a combination of growth factor or surface treatment.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제38권1호
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• pp.2-8
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• 2012

Introduction: Auto-tooth bone graft material consists of 55% inorganic hydroxyapatite (HA) and 45% organic substances. Inorganic HA possesses properties of bone in terms of the combining and dissociating of calcium and phosphate. The organic substances include bone morphogenetic protein and proteins which have osteoinduction capacity, as well as the type I collagen identical to that found in alveolar bone. Auto-tooth bone graft material is useful as it supports excellent bone regeneration capacity and minimizes the possibility of foreign body reaction,genetic diseases and disease transmission. Materials and Methods: Implant placement combined with osteoinductive regeneration,preservation of extraction socket, maxillary sinus augmentation, and ridge augmentation using block type,powder type, and block+powder type autobone graft materialwere performed for 250 patients with alveolar bone defect and who visited the Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University from September 2009 to August 2011. Results: Clinical assessment: Among the 250 patients of auto-tooth bone graft, clinical assessment was performed for 133 cases of implant placement. The average initial stabilization of placed implants was 74 implant stability quotient (ISQ). Radiological assessment: The average loss of crestal bone in the mandible as measured 6 months on the average after the application of prosthesis load was 0.29 mm, ranging from 0 mm to 3.0 mm. Histological assessment: In the histological assessment, formation of new bone, densified lamellated bone, trabecular bones, osteoblast, and planting fixtures were investigated. Conclusion: Based on these results, we concluded that auto-tooth bone graft material should be researched further as a good bone graft material with osteoconduction and osteoinduction capacities to replace autogenous bone, which has many limitations.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권3호
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• pp.34-41
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• 1990

The pilomatricoma (calcifying epithelioma of Malherbe) is rare benign hard, spherical and freely movable cutaneous tumor, which was differentiated from hair cells, particulary hair cortex cells. It is usually occured as a single, asymptomatic, 0.5 cm to 3.0 cm sized, deep seated, firm nodule, covered by normal or pink skin. It arises chiefly in young people, including children, and most often in the head, neck and upper extrimites. The authers experienced a case of pilomatricoma which occured in preauricular region. This case was summarized as follows. 1. 10 years old female has suffered from hard subepidermal mass on preauricular area and she visited our out patient clinic. So we performed surgical extirpation and the excised specimen was pathologically examined. 2. Grossly the tumor measures 2.0 cm in diameter and firm, bosselated, spherical shaped which covered by a thin layer of fibrous tissue. On cut section, it shows spicular gritty surfaces, well encapsulation, interwoven and keratotic lamellae. 3. Histopathologically, the epithelial masses of the tumor are composed of two type of cells, basophilic cells and shodow cells. The basophilic cells resemble hair matrix cells which posses round or elogated, deeply basophilic nuclei and scanty cytoplasm. The shadow cells show a central, unstained shadow at the site of the lost nucleus. Gradual development of basophilic cells into shadow cells can be observed. Foci of calcification are present within the lobule of shadow cells. The stroma of the tumor shows a considerable foreign body giant cell reaction adjacent to the shadow cells. 4. No recurrence was observed until post-operative 40 months.