• 대한기관식도과학회지
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• 제17권1호
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• pp.57-60
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• 2011

Spontaneous tonsillar bleeding is a rare condition in ENT unit. Almost reported cases have been related to infection of tonsils. Prior to introduction of antibiotics, spontaneous tonsillar bleeding was usually related to superficial capsular bleeding due to acute or chronic tonsillitis. The presented case is a 36-year old healthy man without history of acute, chronic tonsillitis, and coagulation disorder who complained of dyspnea and oropharyngeal foreign body sensation after vomitting. Examination revealed a reddish polypoid mass of the right tonsil. Furthermore, the mass pushed uvula and tongue base, caused nearly total obstruction of oropharynx. All rountine laboratory test results were within normal limits. Computed tomography (CT) showed low density mass of attached in upper pole of right tonsil without enhancement. We performed tonsillectomy including the reddish polypoid mass under general anesthesia. The pathology revealed lymphoepithelial tissue with reactive hyperplasia. This is the first reported tonsillar hematoma presenting as a large oropharyngeal mass which was caused by vomitting.

• Journal of Species Research
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• 제9권4호
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• pp.346-361
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• 2020

In the project of a comprehensive investigation of indigenous prokaryotic species in Korea, a total of 39 bacterial strains phylogenetically belonging to the classes Betaproteobacteria and Gammaproteobacteria were isolated from various environmental sources such as soil, cultivated soil, sludge, seawater, marine sediment, algae, human, tree, moss, tidal flat, beach sand and lagoon. Phylogenetic analysis based on 16S rRNA gene sequences revealed that 39 strains showed the high sequence similarities (≥98.7%) to the closest type strains and formed robust phylogenetic clades with closely related species in the classes Betaproteobacteria and Gammaproteobacteria. In the present study, we report 14 species of 9 genera of four families of two orders in the class Betaproteobacteria and 25 species of 21 genera of 15 families of eight orders in the class Gammaproteobacteria, which have not been reported in Korea. Morphological, biochemical, and physiological characteristics, isolation sources, and NIBR deposit numbers are described in the species descriptions.

• 대한의생명과학회지
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• 제15권1호
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• pp.37-45
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• 2009

Insect cell cultures have become important tools in the production of biological substances for use in a variety of research, human and veterinary medicine, and pest control applications. These applications often require the introduction of foreign DNA into the cells and have generally used methods originally developed for use with human and other mammalian cell cultures. While these methods can be successfully employed, they are often less efficient with insect cells and frequently involve complex procedures or require specialized equipment. Even when they do work, they may require substantial modification because of differences in the culture medium or growth patterns of insect cells. In this study, We have optimized transfection conditions of Sf9 cell line using insect expression vector pIZT/V5-His which expresses green fluorescent protein effectively. Human stem cell factor (hSCF) is a glycoprotein that plays a key role in hematopoiesis acting both as a positive and negative regulator, often in synergy with other cytokines. It also plays a key role in mast cell development, gametogenesis, and melanogenesis. It can exist in membrane-bound form and in proteolytically released soluble form. As determined by an enzyme-linked immunosorbent assay performed, hSCF level in supernatant averaged 995ng/ml. The human hSCF was partially purified by immunoaffinity chromatography and analyzed with sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. The results show that the hSCF has N-linked carbohydrate and corresponds to the soluble form, at or about 223 amino acids in length. The findings suggest functional importance for soluble hSCF in cells.

• 척추신경추나의학회지
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• 제13권1호
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• pp.55-68
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• 2018

Objectives: The objective of this study was to review the trends of Korean medicine-based treatment for thoracic outlet syndrome(TOS). Methods: Korean and foreign on-line databases(Pubmed, Cochran Library, CNKI, NDSL KISS and OASIS) were researched for articles discussing Korean medicine-based treatment for TOS. Repeated articles, review articles, commentaries, and those not relevant to the topic of study were excluded. Results: The total number of studies selected was 26, which included 18 case reports and 8 randomized controlled trials(RCT). In these studies, acupuncture, pharmacopuncture, acupotomy, and warm acupuncture were used as interventions for TOS.Chuna therapy was found to be the most commonly used combination treatment. Despite the high prevalence of TOS, only 3 case reports of the 26 studies selected in this review were published in Korean academic journals. Conclusions: In this study, we analyzed the trends of traditional Korean medicine-based treatment for TOS. The results showed that Korean medicine-based treatment could be an effective method for treating TOS.

• 문화기술의 융합
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• 제6권4호
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• pp.591-598
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• 2020

2020년 2월 COVID-19의 1차 대유행 이후 국내외적으로 원격의료에 대한 수요가 크게 증가하였고, 이에 대부분의 국가에서는 원격의료 관련 규제를 완화하였다. 우리나라 역시 2월 이후 한시적으로 '비대면진료'라는 이름으로 원격의료를 허용하고 있다. 원격의료는 만성질환 관리에 매우 효과적이고 정보통신기술의 발전에 따라 적용 가능한 진료과목이 점차 확대되고 있어, 의료서비스 질 향상 및 새로운 진료모형의 창출에 기여할 것으로 기대된다. 그러나 원격의료 참여를 매개로 한 의료공급자 간 차별화 효과를 낳을 수 있고 이는 대형병원 쏠림의 왜곡된 의료서비스산업구조의 문제점을 더욱 악화시킬 우려가 있다. 따라서 일차 진료기관을 중심으로 한 만성질환 관리 주치의제도의 정착을 통해 원격의료의 확대와 지역의료기반의 안정화를 동시에 도모하고, 상급종합병원 및 외국인환자유치기관에 대해서는 재외국민과 외국인 대상 원격의료 제공 능력을 지원하는 이원적 지원 정책 추진이 필요하다.

• 한국컴퓨터정보학회논문지
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• 제20권11호
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• pp.175-181
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• 2015

In this paper, based on the reference, we try to review the second issues about opening medical market and health care privatization by each topic and propose the measures and alternatives. Currently, in Korea, connection with launch of the WTO system and force of the FTA, the medical industries getting liberalization and globalization. Thus, it is expected to plunge to full-free competition system, and Korean medical institutions started the global competition which completely different dimension. It means that according to the liberalization of the healthcare market the real problem can be caused and also, the incessant discussion and effort for the implementation of international community are needed. Regard to attracting foreign patients and opening medical markets, the government also spreading the continued advancement strategy politically until now. However, generating problems with implication is inevitable and measures and alternatives to it are also needed. In accordance with the opening, the accompanying suggestions is medical privatization, that is, whether the health care pursue the profit not the not-for-profit and the current hospitals in Korea they are leaved as non-profit hospitals and let the make the subsidiary as general commercial enterprises, it seems indirect. However, it is like a healthcare privatization virtually thus, implication seem be large. Of course, through the public opinion and legal reservation, the liberalization and privatization of medical market can be delayed or not forced. It would be not fit in the flow of the inevitable globalization, it can be inhibited national interest and economic development also, and it can be the critical implications which shake the health system and collapse of the domestic health care market.

• 한국임상약학회지
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• 제20권1호
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• pp.56-65
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• 2010

Objective: This study aimed to develop information materials on vaccine's safety and adverse events which can be utilized by healthcare professionals when prescribing, dispensing and administering vaccines and also by non-healthcare professionals such as pharmaceutical distributors of vaccine. Methods: Information materials regarding vaccines from domestic and foreign governmental organizations, academies, medical organizations and pharmaceutical companies were reviewed. Advisory Committee which consisted of experts in the areas of the vaccine's safety verified the contents and the final information material. Results: Based on the collected data, we developed general guidelines including vaccine constituents, safety information and adverse events of each vaccines, storage and handling, and labeling information. The information materials were developed for both healthcare professionals and non-healthcare professionals such as vaccine distributors. Conclusion: Information materials on vaccine's safety and adverse events developed from this study could be utilized to provide useful information on the vaccine to the medical institutions and distributors.

• 대한임상독성학회지
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• 제8권2호
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• pp.61-68
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• 2010

Purpose: Poisoning is a major health problem for the elderly, and poisoning can cause fatal side effects. However, the characteristics and clinical features of elderly patients with acute poisoning have not been well studied in the previous domestic research. So, we tried to analyze the clinical characteristics and toxic substances of the patients who were 65 years old or older and who were admitted to the regional emergency medical center due to acute poisoning. Methods: We retrospectively reviewed the medical records and poisoning protocols of the patients who were 65 years of age or older and who had with acute poisoning and who visited the ED in our emergency center from January 2005 to December 2009. We collected the demographic information, the gender, the underlying diseases, the causes and toxic substances, the initial presentation, the treatment and the outcomes. Results: A total of 2179 poisoned patients visited the hospital during 5 years, and among them 244 were 65 years of age or older (11.2%). The mean age was $75.6{\pm}6.9$ years and the male:female ratio was 1:1.7. The most common cause of poisoning was suicide (73.4%) and the most common source of poisonous substances was their own drugs. Of the substances used for poisoning, benzodiazepine was the most common drug (25.8%), followed by sedatives other than benzodiazepine (25.4%), insecticide (12.7%), chemical agents (12.3%) and herbicides (8.2%). The most common initial presentation was mental change (64.8%). When comparing the factors between the three elderly groups, there was no difference in gender, the cause, the substances and the underlying disease. The outcomes of treatment included ICU admission (56.1%), a good condition at discharge (12.7%) and admission to a general ward (12.7%). The overall mortality rate was 10.2% for the elderly patients. Conclusion: In this Korean study, unlike the foreign studies, the most common cause of poisoning in elderly patients was intentional poisoning. The admission rate was 68.8% and mortality rate was 10.2%.

• 재활치료과학
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• 제10권2호
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• pp.53-74
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• 2021

목적 : 본 연구는 아동을 대상으로 하는 운동기능 평가 및 중재방법에 대한 국외 문헌들을 중심으로 분석하고자 하였다. 연구방법 : 본 연구는 2010년 1월부터 2020년 3월까지의 국외 학술지에 게재된 문헌을 PubMed, Cochrane library(Embase)를 통하여 검색하였으며, 주요 검색용어는 motor function test, motor function measure, movement assessment, motor proficiency test, motor scale, motor skill, children을 사용하여 검색하였다. 결과 : 총 37편의 연구 중 14편의 평가, 23편의 중재로 분석되었으며, 중재에 관한 연구 디자인은 모두 RCT design이었다. 운동기능 중재보다 평가 연구가 증가하는 추세를 보였다. 연구분야는 재활분야에서 가장 빈번하였으며, 평가에 관한 연구는 AIMS와 MABC-II, 중재에서는 GMFM이 가장 많이 사용되었다. 중재 종류는 Task-oriented training(6편)이 가장 많이 사용되었다. 결론 : 본 연구는 국외에서 실시된 아동의 운동기능 중재와 평가에 관련된 연구를 분석함으로써 국내 치료사들이 임상에서 효과적인 운동기능 평가와 중재를 선택할 수 있도록 근거를 제공하고자 하였다.

• 융합정보논문지
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• 제9권3호
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• pp.146-151
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• 2019

본 연구는 간호사의 직무 스트레스와 자기효능감과의 관계를 규명하기 위하여 관련 연구의 동향을 고찰하고 텍스트 네트워크 분석을 시행하였다. 선행문헌고찰을 위하여 국내 3곳, 국외 1곳의 데이터베이스를 이용하여 '간호사', '스트레스', '자기효능감', 'nurse', 'stress', 'self-efficacy'를 주요 검색어로 검색하였다. 총 18편의 논문이 대상 문헌으로 선정되었다. 이중 9편의 연구에서 간호사의 직무 스트레스와 자기효능감 간에 통계적으로 유의한 음의 상관관계가 있음을 보고하였다. 그러나 도구의 선택에 있어 번안자에 따라 문항을 선택적으로 사용하여 상이한 결과가 도출되어 동일한 도구를 사용한 다른 논문들과의 비교 분석이 어려웠다. 또한, 18편 논문의 초록에서 키워드를 추출하여 텍스트 네트워크 분석을 시행하였다. 출현 빈도수가 가장 높은 단어는 직무스트레스였고, 이를 기준으로 관계를 분석하였을 때 출현 빈도수가 높은 주요어는 자기효능감, 의료기관, 상관성이었다. 해당 주요어간의 관계를 명확하게 하기 위해 한국형 도구 개발을 통한 영향요인 탐색 연구 수행을 제언한다.