• Title/Summary/Keyword: Folk medicine

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In vivo Antitumor Activity of Mansonone E isolated from Ulmus davidiana var. japonica NAKAI (느릅나무의 근피로부터 분리한 Mansonone E의 항암효과)

  • Cho, Choa-Hyung;Yoon, Won-Ho;Lee, Keyong-Ho
    • Korean Journal of Pharmacognosy
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    • v.35 no.3 s.138
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    • pp.199-202
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    • 2004
  • A highly potent antitumor sesquiterpene O-naphthoquionone has been isolated from Ulmus davidiana, which has been traditionally used as the folk medicine. The structure of this compound was established on the basis of spectral data obtained from UV, IR, MS, and NMR spectrometry, and determined as mansonone E. This compound showed potent antitumor activity on in vivo assay, hollow fiber and xenograft assay.

Hepatoprotective effect of Rumecis Semen

  • Lee, Shin-Seok;Huh, Yeon-Gu;Yim, Dong-Sool;Lee, Sook-Yoen
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2002.07a
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    • pp.242-242
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    • 2002
  • The root of Rumex crispus(Polygonaceae) has been used as one of many oriental medicines ofr the treatment of cathartics, juandice and skin diseases etc. Recently, it is reported as one of anticancer agents and a remedy of acute hepatitis in many traditional medicines. Also, the seed of this plant has been used as a folk medicine for the treatment of digestion problems, liver diseases and many sorts of tumors. In this study we have collected the seed of this plant in rural area and investigated the efficacy of hepatoprotective activity from liver cell damage induced by carbon tetrachloride on mice with methanol extracts, ethylacetate and butanol fractions of this plant

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Pharmaco-Constituents of Crataegus Pinnatifida var. Pubescens Leaves (털산사나무잎의 약효성분)

  • 김정수;김일혁
    • YAKHAK HOEJI
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    • v.37 no.2
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    • pp.193-197
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    • 1993
  • For the investigation of medicinal resources in Crataegus species, a study was carried out to clarify the constituents in the leaves of Crataegus Pinnatifida var. pubescens (Rosaceae), of which fruits have been used to stomachic, digestive, astringent, analgesic, and cardiotonic, etc. as a folk medicine in Korea. From the n-BuOH fraction of MeOH extract two flavone glycosides, vitexin(apigenin-8-C-$\beta$-D-glucopyranoside) and 2"-O-rhamnosyl vitexin(apigenin-8-C-$\alpha$-L-rhamnosyl-(1$\rightarrow$2)-$\beta$-D-glucopyrano side) were isolated and identified on the basis of their physico-chemical properties and spectroscopic evidences(UV, IR, NMR, FAB-Mass etc.) in comparision with authentic samples.amples.

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Anti-inflammatory Activity of Propolis

  • Park, Eun-Hee;Kim, Sun-Hee;Park, Soo-Sun
    • Archives of Pharmacal Research
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    • v.19 no.5
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    • pp.337-341
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    • 1996
  • Propolid (bee-glue), known as a folk medicine, is a lipo;hilic material found in honeybee hives. In the present study on the anti-inflammatory effect of Korean propolis, it was extracted with ethanol, and used as a test material. The $LD_{50}$ value with the oral administration of ethanolic extract of Korean propolis (EEKP) was higher than 2g/kg in mice. The oral administration of the propolis extract (100mg/kg) significantly inhibited the development of hind paw edema induced by carrageenin in rats. the oral pretreatment of the propolis extract markedly inhibited the increase in vascular permeability and the number of writhing induced by acetic acetic acid in mice. Propolis extract, 50 and 100 mg/kg p.o. per day for 7 days, produced a significant inhibitory effect on granuloma and exudate formation in rats. This inhibitory effect was enhanced with the concomitant use of prednisolone (2.5 mg/kg). These results suggest that Korean propolis apparently has a strong anti-inflammatory activity.

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Inhibition of Monamine Oxidase by a Flavone and Its Glycoside from Ixeris dentata Nakai

  • Chung, Ha-Sook
    • Preventive Nutrition and Food Science
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    • v.8 no.2
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    • pp.141-144
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    • 2003
  • Ixeris dentata Nakai (Compositae) is a perennial herb which has been used as a folk medicine for treating diabetes and gastroenteric troubles in Korea. Active compounds were isolated from the aerial parts of Ixeris dentata through the bioassay-guided fractionation and isolation method evaluated for inhibition of monoamine oxidase (MAO) in vitro. The compounds were identified as 5,7,3',4'-tetrahydroxyflavone (1) and 5,7,3',4'- tetrahydroxyflavone 7-glucoside (2), based on physical and spectroscopic characteristics. Compounds 1 and 2 showed a selective inhibition of type B MAO (MAO-B) activity, with IC/sub 50/ values of 15.3 μM and 36.4 μM, respectively, but did not inhibit type A MAO (MAO-A) activity.

Caring Types in Mothers of Children with Athma : Q Methodology (천식 환아 어머니의 돌봄 유형: Q 방법론 적용)

  • Oh Won Oak
    • Child Health Nursing Research
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    • v.6 no.1
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    • pp.89-102
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    • 2000
  • Asthma is one of the most common chronic disease of childhood. Although an improved understanding of the pathophysiology of asthma has had a positive impact on the treatment and management of the disease, there has been a gradual but significant increase in asthma mortality. Also, mother's caring type is the essential factor in management of the child with asthma. The purpose of this study is to identify and understand the caring patterns of mathers of children with Athma by Q methodology. As a research method, 35 Q-statements were collected through individual interviews and review of related literatures. 37 subjects were interviewed and the data were analyzed by the PC QUANL program with principal component analysis. The were 3 different caring types classified as follows : Type I was the therapeutic compliance obeying type, compliancing medication and preventing cold etc. Type II was the physical strengthening type, taking Chinese medicine and folk remedy etc. Type III was the environment control type, managing house and environment clearly and ventilating room air etc. Therefore, it needs considering above each type in nursing care of the family and children with asthma.

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Anti-diabetic Agents from Medicinal Plants Inhibitory Activity of Schizonepeta tenuifolia Spikes on the Diabetogenesis by Streptozotocin in Mice

  • Kim, Chang-Jong;Lim, Jung-Sik;Cho, Seung-Kil
    • Archives of Pharmacal Research
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    • v.19 no.6
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    • pp.441-446
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    • 1996
  • The Schizonepeta tenuifolia spikes (STS) have been used as a traditional folk medicine for antiinflammatory, analgesic, anti-pyretic and anti-spasmodic purpose in Korea. Phytosterols (mixture of campesterol 3.68%, stigmasterol 2.30% and ${\beta}$-sitosterol 94.02%) and hesperidin were isolated by chromatography from ether and n-BuOH fractions of STS respectively. These compounds significantly reduced the blood glucose level and lessened the loss of body weight and water consumption dose-dependently when administered at a i.p. doses of 10 and 20 mg/kg for 4 days after the i.v. injection of streptozotocin (I 80 mg/kg). In the morphologic study, these compounds showed protective activity on the pancreatic islets, especially .betha.-cells, from the degenerative changes by streptozotocin.

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Antioxidant and Liver-protective Effects of Caesalpinia sappan (소목 추출물의 항산화 및 간보호작용)

  • Ha, Hun
    • Environmental Analysis Health and Toxicology
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    • v.17 no.3
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    • pp.261-264
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    • 2002
  • The heartwood of Caeralpinia sappan L. (Leguminosae) has been used to activate blood flow, remove blood stasis, reduce swelling and relieve pain in Korean folk medicine. In this study. the antioxidant effects of this crude drug and its hepatoprotective activity on CCl$_4$-induced liver injury in rats were evaluated. The levels of antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) reduced by CCl$_4$treatment, were recovered by this crude drug. It is suggested that Caesalpinia sappan L. have antioxidant effect. The increased levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) by CCl$_4$were also recovered by treatment with this crude drug. These results can be attributed to the agent's antioxidant and membrane - stabilizing actions.

A Clinical Report on Episodic Vertigo with Meniere's Disease Treated by Saam Acupuncture Sojangjungkyuk (사암침 소장정격을 이용한 Meniere's disease의 발작성 현훈 치험 1례)

  • Oh, Ki-Chul
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.16 no.1
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    • pp.35-44
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    • 2012
  • Objectives The purpose of this study is to report the effect of oriental demonstration treatment for episodic vertigo of Meniere's disease. Meniere's Disease characterized by recurrent prostrating episodic vertigo, nausea, vomiting, sensory hearing loss, tinnitus, and a feeling of fullness in the ear associated with generalized dilation of the membranous labyrinth (endolymphatic hydrops). The cause of Meniere's disease is unknown, and the pathophysiology is poorly understood. Methods We experienced one case of Meniere's disease treated with Asian medical treatment, acupuncture and herbal medication. 64-year-old female patient was diagnosed with Meniere's disease by western medical doctor. Methods: Saam acupuncture Sojangjungkyuk applied to the patient. Results After treatment her episodic vertigo, nausea, vomiting and endolymphatic hydrops were decreased but the level of tinnitus it was not improved as much as other symptoms. Conclusions Saam Acupuncture of Asian medical treatment could be safe and effective.

Inhibition of Angiogenesis by Propolis

  • Song, Yun-Seon;Park, Eun-Hee;Jung, Kyung-Ja;Jin, Changbae
    • Archives of Pharmacal Research
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    • v.25 no.4
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    • pp.500-504
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    • 2002
  • Propolis, obtained from honeybee hives, has been used in Oriental folk medicine as an anti-inflammatory, anti-carcinogenic, and immunomodulatory agent. There is considerable evidence suggesting that angiogenesis and chronic inflammation are codependent. Blockage of angiogenesis results in an anti-inflammatory effect. Ethanol (EEP) and ether extracts of propolis (REP), and caffeic acid phenethyl ester (CAPE), an active component of propolis, were examined for their anti-angiogenic activities using the chick embryo chorioallantoic membrane (CAM), and the calf pulmonary arterial endothelial (CPAE) cell proliferation, assays. The presence of EEP, REP and CAPE inhibited angiogenesis in the CAM assay and the proliferation of CPAE cells. The results suggest that anti-angiogenic activities of EEP, REP and CAPE are also responsible for their anti-inflammatory effect.