• IMMUNE NETWORK
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• v.14 no.1
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• pp.7-13
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• 2014

Molecular mimicry is an attractive mechanism for triggering autoimmunity. In this review, we explore the potential role of evolutionary conserved bacterial proteins in the production of autoantibodies with focus on granulomatosis with polyangiitis (GPA) and rheumatoid arthritis (RA). Seven autoantigens characterized in GPA and RA were BLASTed against a bacterial protein database. Of the seven autoantigens, proteinase 3, type II collagen, binding immunoglobulin protein, glucose-6-phosphate isomerase, ${\alpha}$-enolase, and heterogeneous nuclear ribonuclear protein have well-conserved bacterial orthologs. Importantly, those bacterial orthologs are also found in human-associated bacteria. The wide distribution of the highly conserved stress proteins or enzymes among the members of the normal flora and common infectious microorganisms raises a new question on how cross-reactive autoantibodies are not produced during the immune response to these bacteria in most healthy people. Understanding the mechanisms that deselect auto-reactive B cell clones during the germinal center reaction to homologous foreign antigens may provide a novel strategy to treat autoimmune diseases.

• International Commerce and Information Review
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• v.12 no.2
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• pp.409-438
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• 2010

According to Sun Tzu's Art of War, "if you know yourself and your enemy you win hundred battles out of a hundred." This is also apply for international business field. International business negotiation will not be failed if you know counter party's behavior and understand their culture and customs. The cooperative approach is known as interest-based negotiation. Interest-based negotiation is particularly effective in a global business characterized by diversity. We often need to reach agreement with people who are different from us - culturally, ethnically, or economically. If we cannot get beyond the differences, they can create obstacles to agreement. To do this, we need to focus on the interests of the parties instead of on the parties' differences. Every culture has their own distinctive feature that the people from outside seems not understand but they must have the optimistic attitude which complies with. The purpose of this paper, from the point of view above, is to examine cultural differences that could make sure comparative advantage in business negotiation of the enterprises who eager to expand their market or to invest internationally. This paper especially shows cultural deferences among Korea, China and Japan in terms of business we must consider.

• The Journal of Information Systems
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• v.22 no.3
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• pp.1-24
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• 2013

SNS(Social Network Services) is being recognized as an important part in our society, individual lives and corporate business aspects, and the influence of SNS is growing explosively as expansion and supply of infrastructures that support mobile environments increase. Previous studies related to SNS were focused on user acceptance of new technology, based on Technology Acceptance Model(TAM). However, they had a limitation to focus on technology acceptance, without the consideration of personal and behavioral factors in SNS use. However, above all, successful SNS requires the understanding of users who are active on the network. Therefore, from the user's perspective, this study attempted a multi-dimensional approach by reflecting characteristics that come from SNS usage. This study considered user innovation, virtual skill, self-efficacy, social pressure and network effect as independent variables, and perceived ease-of-use, perceived usefulness and perceived value as mediating variables, and intention-to-use as dependent variable. The result showed that user innovation, self-efficacy, social pressure and network effect had a significant effect on the mediating variables. The practical contribution of this study is to suggest useful decision alternatives concerned to marketing strategy for acquiring and retaining lone-term customers related to SNS business.

• Journal of Global Scholars of Marketing Science
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• v.7
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• pp.1-23
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• 2001

Two of most important industries in Changwon, the distribution industry and the construction industry have been threatened by the recent economic downturn. Rehabilitating plans for traditional markets tend to focus on renovation of facilities rather than on the managerial solution. Traditional market plays vital roles as a social safety net and a source of development of regional economy. Modernization of facilities and differentiation of business areas are two most important issues for the revitalization of the traditional market. Traditional markets should adopt a strategy which can make a difference in characteristics of the market, regional culture, regional industry and consumer behavior of the region. Purposes of this study are: first, to understand characteristics of traditional markets in Changwon, second, to draw implications for administrative and financial supports for traditional markets in Changwon.

• Korean Journal of Occupational Health Nursing
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• v.7 no.2
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• pp.121-129
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• 1998

Health behavior constitutes the single most important factor in an individual's health maintenance program. Pender's health promotion model emphasizes the positive aspects of health-seeking behavior hut omits some negative ones. Although Pender's work does include the concept of barriers, the main focus is upon health habits rather than upon the interaction between the consumer and the health care system. Therefore, since individuals actually do face many barriers in their health-seeking behavior, the present study deals with negative concepts-the barriers to health and healthy behavior. For this reason the expression health-seeking behavior was chosen over health promotion. In conclusion, the results show that barriers to health-seeking behavior are causal factors that could explain and predict the health-seeking behavior of middle life women. Midlife women shows that they have barriers to health-seeking behavior especially in inconvenience, cost, healthcenter site-related problem, relationship, fear. These findings suggest the need to develop a nursing strategy to improve the empowerment of self-determination in middle-aged women. Consequently, a goal of nursing care for middle-aged women should be to help them pursue health care with a greater degree of self-sufficiency.

• Culinary science and hospitality research
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• v.8 no.3
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• pp.123-146
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• 2002

Outsourcing is procuring of outside resources, other than core resources for core competence, by a contract, from which a corporate can focus its core resources on core business. The outsourcing strategies of Korea tourist hotel business are in a rudimentary stage, which has been limited in simple work areas such as housekeeping services, room maid services, parking control services, security services, janitor services, laundry services, facility management, shuttle bus services, and sterilization services and their purposes are mainly to retrench a burden of employment or firm-fixed expenses. Therefore, the outsourcing strategies of Korea tourist hotel business have the following problems. First, their outsourcing has introduced only for the purpose of retrenching expenses. Second, it tends to deteriorate service quality, due to lack of pre-training. Third, it tends to concentrate their attentions only on simple repetition works. Fourth, their outsourcing is slow adjusted to the needs of business cultures. Outsourcing services in Korea tourist hotel business have never contributed to their basic concepts such as 1) maintenance or enhancement of core competences, 2) promotion of business efficiency through service quality improvement and expense retrenchment, and 3) achievement or enhancement of competitive advantage through enlarging their specialties, cultivating their market, learning new knowledge, and developing their asset. Therefore, this study is to insist on fife necessity of overcoming simple repetitive service outsourcing in tourist hotel business. In order to build a core competence and/or achieve a competitive advantage, the scopes of outsourcing services should be enlarged in Korea tourist hotel business.

• Journal of Information Technology Applications and Management
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• v.21 no.4
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• pp.65-96
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• 2014

To have global competitiveness in newly growing industry, good quality R&D's in convergence technology arerequired. Korean government also started to emphasize the importance of convergence technology as a new engine of growth for the future development. Since 2008, worldwide energy crisis and concerns on low carbon green growth made people focus on the convergence between information technology (IT) and energy technology (ET). However, the R&D performance comparison among the convergence technologies is not well explored so far. Therefore, this study uses Korea's patent citation database to measure the R&D performance of convergence technologies. We adopt technology development cycle, technology spillover analysis, and technology diffusion analysis to see the knowledge flow from R&D industry to others. We find that IT_ET convergence technology generally shows higher R&D performance than other convergence technologies. Contrary to public belief, convergence R&D by big companies has relatively low performance especially measures in technology spillover and technology diffusion. This implies that they might concentrate on delicate Fuel Cell Energy/Environment Technology (FEIT) or Nano Environment/Energy Information Technology (NEIT) rather than general energy information technologies. We also find that Korea's chemical industry may play a crucial role for the growth of other convergence technologies.

• Journal of the Korea Furniture Society
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• v.10 no.1
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• pp.33-42
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• 1999

This study aims to organize the research ways of interior design for clothing stores as a management strategy in the market changing rapidly. The public met their needs in a mass production system. However, the brand-name companies began to create the conditions of consumption for people, there appeared people with new lifestyles and new way of thoughts so that their propensity to consume resulted in consumption activities, and it become varied, individual, and highly qualified. Therefore, in view of consumers' priority, based on SI sales environment this paper aims to create a new image by re-designing the interior and furniture of shops which will help to enhance the image of brand name. Therefore, the brand-name companies will expect a large sale for the new product and it will apply to sales environments of other products and influence them. The purpose of this paper is to find a desirable way to increase sales efficiency for the companies. In order to get a concept and propriety of sales environment design, examined mutual relation to each study of interior design, marketing, and fashion design. Through referring to the documents research of these fields I could get a conception and basic structure for them. Based on the theoretical knowledge, this study was made to show to examine and generalize the existing sales environments and situations and set up a new concept for this. It will apply to interior design and store holds and present a new design alternative for improvement.

• Korean System Dynamics Review
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• v.9 no.2
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• pp.77-103
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• 2008

In order to respond dynamic changes in the global distribution system, the City of Pyeongtaek hope to expand port facilities and its hinterlands. In specific, it plans to designate these areas as free economic zones(FEZ), synthesizing the whole procedures from the development proposals to the operation and management. This paper examines the proposed urban development strategies focused on Pyeongtaek port which still reveals critical weakness as a gateway port backed up by the Seoul Metropolitan Areas. In order to enhance the global competitiveness of Pyeongtaek port, theoretically it depends on Geo Coyle's ACTIFELD methods. In addition to the traditional quantitative data, Coyle's ACTIFELD methods emphasize qualitative approaches, all of which would facilitate structural and systemic analyses of complex social phenomena. Applying ACTIFELD methods, this paper proposes that the City of Pyeongtaek should focus on three alternatives. That is, Pyeongtaek's policy priority should be given to ts he port city based on the key concepts of Supply Chain Management(SCM), Co-opetition supporting city, and waterfront-initiated urban development.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.7
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• pp.1831-1853
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• 2012

By sending periodically short bursts of traffic to reduce legit transmission control protocol (TCP) traffic, the low-rate denial of service (LDoS) attacks are hard to be detected and may endanger covertly a network for a long period. Traditionally, LDoS detecting methods mainly concentrate on the attack stream with feature matching, and only a limited number of attack patterns can be detected off-line with high cost. Recent researches divert focus from the attack stream to the traffic anomalies induced by LDoS attacks, which can detect more kinds of attacks with higher efficiency. However, the limited number of abnormal characteristics and the inadequacy of judgment rules may cause wrong decision in some particular situations. In this paper, we address the problem of detecting LDoS attacks and present a scheme based on the fluctuant features of legit TCP and acknowledgment (ACK) traffic. In the scheme, we define judgment criteria which used to identify LDoS attacks in real time at an optimal detection cost. We evaluate the performance of our strategy in real-world network topologies. Simulations results clearly demonstrate the superiority of the method proposed in detecting LDoS attacks.