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Impact of DPN on Deep Nano-technology Device Employing Dual Poly Gate (Nano-technology에 도입된 Dual Poly Gate에서의 DPN 공정 연구)

  • Kim, Chang-Jib;Roh, Yong-Han
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.4
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    • pp.296-299
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    • 2008
  • The effects of radio frequency (RF) source power for decoupled plasma nitridation (DPN) process on the electrical properties and Fowler-Nordheim (FN) stress immunity of the oxynitride gate dielectrics for deep nano-technology devices has been investigated. With increase of RF source power, the threshold voltage (Vth) of a NMOS transistor(TR) decreased and that of a PMOS transistor increased, indicating that the increase of nitrogen incorporation in the oxynitride layer due to higher RF source power induced more positive fixed charges. The improved off-current characteristics and wafer uniformity of PMOS Vth were observed with higher RF source power. FN stress immunity, however, has been degenerated with increasing RF source power, which was attributed to the increased trap sites in the oxynitride layer. With the experimental results, we could optimize the DPN process minimizing the power consumption of a device and satisfying the gate oxide reliability.

On the Hydrodynamic Coefficients of a 3-dimensional Body with a Forward Speed (전진속도를 고려한 3차원 물체의 동유체력해석)

  • J.K.,Choi;K.P.,Rhee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.25 no.3
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    • pp.19-25
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    • 1988
  • The three-dimensional boundary value problem for the unsteady motion of a ship which is translating and oscillating on the free surface of a deep water formulated. Under the assumption that the forward speed is small and order of $\varepsilon$, all formulations are made up to the first order of $\varepsilon$. For the numerical calculation, the three-dimensional source distribution method is applied, and the triangular elements are used to represent the hull surface. The results for the added mass and the damping coefficient for Series 60, $C_B=0.7$ at Fn=0 and Fn=0.2 shows good agreements with those of Inglis, Chang, and Inglis and Price.

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Karyotype of Dwarf Loach, Kichulchoia brevifasciata (Pisces: Cobitidae) from Korea (미꾸리과 소형어류 좀수수치, Kichulchoia brevifasciata의 핵형)

  • Kim, Ik-Soo;Kim, Eun-Jin
    • Korean Journal of Ichthyology
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    • v.20 no.1
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    • pp.61-65
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    • 2008
  • The karyotype analysis of Kichulchoia brevifasciata was carried out, known as an end-angered small endemic cobitid fish of Korea. Five females and one male were collected from Geum-san-myeon, Goheung-gun, Jeollanam-do, Korea and its gill, kidney and digestive tract tissues were treated by flame-drying technique. The karyotype was found to be 2n= 48 from 33 cells; 16 meta-submetacentric and 32 subtelo-telocentric chromosomes; 64 FN (fundamental number). This karyotype showed a remarkably different karyotype formula from Niwaella multifasciata which is closely related to this species.

Comparative Analysis of Dissolution and Refolding Processes for Inclusion Body Protein Renaturation (내포체 단백질 재생을 위한 용해 및 재접힘공정의 비교분석)

  • 김창성;김윤하;이은규
    • KSBB Journal
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    • v.13 no.2
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    • pp.133-140
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    • 1998
  • Using rlFN-$\alpha$ and rhGH as the model proteins, the refolding performances of the published processes were evaluated and compared. Key engineering parameters such as the type of denaturant and this concentration, protein concentration in the refolding buffer, and pH and ionic strength of the buffer were experimentally investigated. Furthermore, the role of a co-solvent of surfactant type in aggregation reduction was also studied. Of the denaturants tested (8M urea, 6M guanidine HCI, 0.5% SDS), SDS at alkaline pH (9.5) and ambient temperature gave the highest recovery yield. The SDS process was effective in the refolding of observed where dissolution proceeded better under lower strength (10 mM) but aggregation was suppressed under higher strength (>50 mM.) When PEG-4000 and/or Tween were added as co-solvent or refolding-enhancing additive, 1.6-2 times higher yield was realized. The‘masking’of the hyrophobic patches located on the surface of the protein with the surfactant molecules was believed to be responsible for the considerable reduction in aggregation during refolding.

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Synthesis of Silver Nanoplates with Fibronectin Nanofibril Template and Their SERS Applications

  • Wang, Li;Sun, Yujing;Cui, Yuncheng;Wang, Jiku;Li, Zhuang
    • Bulletin of the Korean Chemical Society
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    • v.34 no.2
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    • pp.443-446
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    • 2013
  • In this work, a novel strategy is provided to prepare silver nanoplates by a fibronectin (Fn) nanofibril template. First, Fn molecules were controlled to assemble into amyloid-like nanofibrils in highly concentrated ethanol aqueous solution. The resultant nanofibrils could serve as a soft template to direct the formation of silver nanoplates. It is worth noting that the silver nanoplates are excellent surface-enhanced Raman scattering (SERS) substrate with 4-aminothiophenol (4-ATP) molecule as a test probe. This high active SERS substrate can also be used to detect drug molecule, 2-thiouracil with high sensitivity.

Prior Immunization with Fusobacterium Nucleatum Interferes with Opsonophagocytosis Function of Sera against Porphyromonas Gingivalis (Fusobacterium nucleatum을 이용한 사전면역이 면역혈청의 Porphyromonas gingivalis에 대한 탐균작용의 장애에 대한 연구)

  • Choi, Jeom-Il;Borrello, Melinda A.;Cutler, Christopher W.;Zauderer, Maurice
    • Journal of Periodontal and Implant Science
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    • v.30 no.1
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    • pp.105-111
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    • 2000
  • 본 연구는 Balb/c mice를 이용하여 Porphyromonas gingivalis 381(Pg)로 면역하기 전에 Fusobacterium nucleatum ATCC 10953(Fn)로 면역한 Group 1(N=10)과 Pg 로만 단독 면역을 시행한 Group 2(N=10)로부터 채취한 혈청의 Pg에 대한 식균능력을 비교하는 데 그 목적이 있다. 면역 후 혈청항체는 Pg에 대해 현저히 상승하였으나, 두 그룹간의 평균 항체역가는 통계적으로 차이가 없었다. 식균능력을 비교한 결과, Pg로만 단독 면역한 경우 식균능력이 Fn으로 먼저 면역한 Group 1의 경우보다 현저히 높았으며, 혈청항체역가와 식균지수와는 긴밀한 상관관계를 보였다. 결론적으로 치주세균의 사전 감염은 후속적인 세균감염에 대한 숙주 면역기능(식균능력)에 교란을 가져 올 수 있다.

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The Effect of Alloying Elements on Weldability and Corrosion Resistance of Austenitic Stainless Steels(I) (오스테나이트계 스테인리스강의 용접성과 내식성에 미치는 합금원소의 영향(I) - 응고균열 감수성을 중심으로 -)

  • Jeong, Ho-Shin;Lee, Yun-Young;Bae, Dong-Soo
    • Journal of Welding and Joining
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    • v.30 no.3
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    • pp.57-65
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    • 2012
  • The interest of austenitic heat resistant stainless steels containing high Si has increased because they have higher resistance of oxidation and higher strength at high temperature than STS 310. This study carried out Varestraint test for evaluation of solidification cracking sensitivity of 14 different stainless steels. As a result of Varestraint test, all specimens solidified as primary ferrite, and solidification crack sensitivity increased with adding $N_2$ to shielding gas. Nb and W had beneficial effect on solidification crack resistance in case of less than FN 2 containing, but crack sensitivity increased with Nb and W in case of more than FN 2. Ce had beneficial effect on solidification crack resistance but impaired weld bead appearance.

Field Emission from Free-standing Nanomembrane For High Energy Ion Detection (Free-standing 박막의 전계 방출 특성을 이용한 고에너지 이온 디텍터에 관한 연구)

  • Park, Jong-Hoo
    • Journal of the Korean Magnetics Society
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    • v.21 no.5
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    • pp.163-166
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    • 2011
  • We describe modified Fowler-Nordheim (FN) field emission equation for the free-standing nanomembrane cathode, which has mechanical degrees of freedom. The derived FN equation agrees well with the experimental data. The free-standing nanomambrane cathode demonstrates its unique ability to detect large biomolecure ions.

Cloning and Characterization of Directly Amplified Antiviral Gene Interferon Alpha-2b (HulFN$\{alpha}$-2b) from Human Leukocytes Chromosomal DNA

  • Behravan, Javad;Ahmadpour, Hassan
    • Archives of Pharmacal Research
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    • v.27 no.7
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    • pp.776-780
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    • 2004
  • Interferons are cytokines that confer resistance to viral infection and inhibit cellular proliferation. The interferon alpha gene from human blood samples was amplified, cloned and expressed in E. coli (BL21). Leukocyte chromosomal DNA was used as a source of template DNA. Using specific primers, the gene for HulFN$\{alpha}$-2b was amplified and inserted into the E. coli vector, pET21b, by ligation of the HindIII and BamHI linkers of the vector and insert. The insert was further analyzed by PCR, DNA restriction mapping and sequencing, and expressed in a suitable E. coli strain. The production of this important cellular protein in the laboratory has significant applications in production of the recombinant pharmaceutical proteins.

Karyotypic Analysis of Chicken Grunt, Parapristipoma trilimeatum, Small Yellow Croaker, Larimichthys polyactis, and Brown Croaker, Miichthys miiuy

  • Park, In-Seok;Gil, Hyun Woo
    • Development and Reproduction
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    • v.23 no.1
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    • pp.73-78
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    • 2019
  • To clarify the cytogenetic features of the chicken grunt, Parapristipoma trilineatum, small yellow croaker, Larimichthys polyactis, and brown croaker, Miichthys miiuy, in Jeju, Korea, karyotype analysis was performed. The karyotype of chicken grunt and brown croaker consists of 24 pairs of telocentrics [2n=48, fundamental number (FN)=48], and small yellow croaker consists of 3 pairs of submetacentrics and 21 pairs of telocentrics (2n=48, FN=54). No evidence of polymorphism, including aneuploidy or sex-related heteromorphic chromosomes, was found in any specimens examined in this study.