• Title/Summary/Keyword: Fixed Effects

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Dietary Sulfur Amino Acids Can Spare Taurine in Rock Bream Oplegnathus fasciatus

  • Ferreira, Fernando Magalhaes;Yun, Hyeonho;Park, Youngjin;Lee, Seunghan;Park, Gunhyun;Bai, Sungchul C.
    • Fisheries and Aquatic Sciences
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    • v.18 no.3
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    • pp.249-255
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    • 2015
  • An 8 week feeding trial was conducted to evaluate whether methionine and cysteine would effectively spare taurine supplementation on growth performance in juvenile rock bream Oplegnathus fasciatus. Triplicate groups of 25 fish averaging $2.74{\pm}0.04g$ ($mean{\pm}SD$) were fed one of the experimental diets. Five experimental diets including a fish meal based control diet were prepared by adding sulfur amino acid at fixed level of 1.0% and taurine at graded levels of 0%, 0.25%, 0.5% and 1.0% ($S+Tau_0$, $S+Tau_{0.25}$, $S+Tau_{0.5}$ and $S+Tau_{1.0}$, respectively). After the feeding trial, growth performance of fish fed the $S+Tau_{0.25}$, $S+Tau_{0.5}$ and $S+Tau_{1.0}$ diets were significantly higher (P < 0.05) than those of fish fed the Control diet. ANOVA test suggested that when sulfur amino acid were supplemented to the diets, the optimum taurine supplementation level could be 0.25% in the diet, and broken line analysis of weight gain indicated a level of 0.33%, for positive effects on growth and feed utilization. Fish whole-body protein content and taurine concentration steadily increased with the increase of dietary level in the presence of sulfur amino acid in the diets. On the other hand, whole-body lipid content significantly decreased with the incremental levels of dietary taurine. In conclusion, the results of the present study clearly indicated that dietary supplementation of methionine and cysteine at a level of 1% could spare 0.25 to 0.33% of taurine in juvenile O. fasciatus diets.

Effects of Selective Light Sources on Seedling Quality of Tomato and Cucumber in Closed Nursery System (폐쇄형 육묘시설 내에서 몇 가지 광원이 토마토와 오이의 묘소질에 미치는 영향)

  • Um, Yeong-Cheol;Jang, Yoon-Ah;Lee, Jun-Gu;Kim, Seung-Yu;Cheong, Seung-Ryong;Oh, Sang-Seok;Cha, Seon-Hwa;Hong, Seong-Chang
    • Journal of Bio-Environment Control
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    • v.18 no.4
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    • pp.370-376
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    • 2009
  • To produce uniform seedlings of tomato and cucumber with inexpensive way, their seedling quality by different light sources was investigated. The raising of seedling was performed by red LED (light emitting diodes), blue LED, red-blue mixed LED or fluorescent light with a fixed PPF(photosynthetic proton flux) level, about $40{\sim}60{\mu}mol{\cdot}m^{-2}{\cdot}sec^{-1}$. In the both tomato and cucumber, the rapid extension of hypocotyledonary axis was observed in Blue LED than fluorescent light, but opposite result was found in Red and mixed LED. During the nursery period of tomato and cucumber, the fresh weight was the highest in Red LED as 74% increasement in tomato and 74% in cucumber. In the case of seedling quality after the tomato nursery, there was no difference in the positions of 1st flower cluster and the number of bearing-flower per flower cluster by each light source. In case of cucumber, until 20th node, the setting ratio of female flower was higher in LED than fluorescent treatment, and also more healthy fruit setting was found in LED. Therefore, we assume that the Red or mixed (Red 2 + Blue 1) LED is more favorable to produce high quality tomato and cucumber seedlings in closed nursery facility.

Ergonomic Design of Office Chair (사무실 의자의 인간공학적 디자인)

  • 곽원모;홍성수;정석길;이상도;이동춘;윤훈용
    • Archives of design research
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    • v.12 no.3
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    • pp.73-80
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    • 1999
  • Many domestic users complain about severe pain to the waist, neck, and shoulder as well as work performance because the domestic chair design was developed with western anthropometry dimension and design criteria. Ergonomic design standards are needed for office chair design to reduce stress and poor physical posture for various user body types. In this study, we have suggested design dimensions recommended from previous studies and Korean anthropometry data. We also have reviewed users' preference dimension through measured subjects and analyzed differences between users' preference dimension and the previous design criteria to verify physical appropriateness. We evaluated general office chairs and adjustable chairs which can adjust to fit each person. we also analyzed how each design dimension was reached and affected the human body by evaluation of physical discomfort and comfort. We have found seat height is very important in a workstation. If the seat height is high, it effects the thigh. If width, height, and angle of the backrest are wrong, fatigue to the shoulder, neck, and waist, etc.. As a result of this experiment, we suggested that the height of a seat for Koreans be 425mm for the fixed type and 365-484mm for the adjustable type. Also other design recommendations were suggested in the thesis. In conclusion, our research will be very important in the database because it provides adjustable ranges to fit user's body types in the various design fields.

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Magnetic Properties and Structure of Co-precipitated Barium Ferrite (BaM) Powders (공침법으로 합성한 바륨 페라이트(BaM) 분말의 결정구조와 자기적 성질)

  • Baek, In-Seung;Nam, In-Tak
    • Journal of the Korean Magnetics Society
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    • v.20 no.4
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    • pp.134-142
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    • 2010
  • Barium ferrite ($BaFe_{12}O_{19}$) powders were synthesized by the co-precipitation method. $Fe^{3+}:Ba^{2+}$ mole ratio was fixed 8 and relative amount of $Fe^{3+}$ and $Ba^{2+}$ was controlled. The effects of the pH (= 8, 9, 10), calcination temperature and time on the morphology, structure and magnetic properties of the barium ferrite particles are characterized using XRD, FESEM, and VSM respectively. Coercivity and magnetization value of powders were changed with calcination temperature and time, relative amount of $Fe^{3+}$ and $Ba^{2+}$ and pH. Single-phase barium ferrite was obtained when pH value was 9 in the investigated range of $Fe^{3+}:Ba^{2+}$ relative amount and secondary phases were appeared at $Fe^{3+}:Ba^{2+}$ relative amount of 14.4 : 1.8. The largest value of magnetization (65.7 emu/g) was obtained when $Fe^{3+}:Ba^{2+}$ mole ratio was 12.8 : 1.6 and calcination temperature was $900^{\circ}C$ with air calcination atmosphere. The largest value of coercivity (5280 Oe) was obtained with $O_2$ calcination atmosphere.

Effects of Chitosan on Fracture Healing in Fractured Rat Model. (골절모델 쥐에서 키토산 투여가 골절치유에 미치는 영향)

  • 서정욱;김은주;한상섭
    • Journal of Life Science
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    • v.14 no.3
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    • pp.385-390
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    • 2004
  • Chitosan is abundant polysaccharide polymer in nature Chitosan has been the subject of much research regarding its potential as a nutritional adjunct and pharmaceutical ingredient. In the present study, we examined fracture-healing process with chitosan administration and low calcium diet in rats. Left femur was fractured and fixed with intramedullary pin. The rats were fed normal diet or low calcium diet and administered chitosan with the doses of 0, 50, 100 and 150ng/ml orally 5 times a week for 10 weeks. Soft X-ray and mechanical testing of all fractured femora was taken. Radiographical finding showed that the callus formation and process of fracture healing was present in all the fractured femora. Mechanical testing indicated that the maximum load and stiffness of femur in rat fed low calcium diet was lower than those of that in rat fed normal diet. No difference in maximum load and stiffness of fractured femora in chitosan treated rat were observed as compared to vehicle treated rat. Chitosan or/and low calcium diet did not affect the ratio of fractured/unfractured femur about maximum load and stiffness. The results suggest that chitosan dose not affect the bone mechanical strength and the process of fracture healing. Low calcium diet does decrease the bone mechanical strength.

EFFECTS OF CARCINOGENICITY AND GROWTH RAGULATORY FACTORS IN HUMAN EPITHELIAL CELLS EXPOSED WITH TOBACCO-SPECIFIC N-NITROSAMINE (흡연특이성 N-Nitrosamine이 인체상피세포의 발암화와 성장조절인자에 미치는 영향)

  • Kim, Seok-Soon;Kim, Chin-Soo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.27 no.2
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    • pp.129-134
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    • 2001
  • Since NNK is one of the most abundant tobacco-specific alkaloids and a strong carcinogenic nitrosamine, it has been used for evaluating a potential of carcinogenicity in the animal models. The present study has attempted to examine the potential of carcinogenicity of NNK in human epithelial cells, from which the cell type the most of cancers including oral cancer and nasal cavity cancer are originated. The cellular model used for the study is a human keratinocyte cell system immortalized by Ad12-SV40 hybrid virus. The cellular system has successfully been used for the carcinogenicity studies because of its limitless life span, epithelial morphology and nontumorigenicity. When cells were treated with a variety of NNK concentrations, levels of saturation density and soft agar colony formation were increased in a dose-dependent fashion. Colonies of large cell aggregates were above 5 at the higher doses. The results indicate that exposure of human cells with NNK induced loss of contact inhibition and increases of anchorage independence and cellular adhesion, which are typical characteristics of the neoplatically transformed cells. When cells were exposed with 100uM NNK for 2hr, mRNA levels of IL-1 and PAI-2 were increased in a dose-dependent manner, but expression of TGF- 1 was not affected. While expression of growth regulatory factors were altered with a short-term exposure, there was no alteration of these factors in the NNK-transformed cells. However, mRNA levels of fibronectin were increased both in the short-term treatment and in the transformation. The results suggest that altered expression of extracellular matrix such as fibronectin following short-term exposure might be fixed in the genome and these altered properties be continuously transfered throughout the cell division. Western blot analysis showed a translocation of PKC- from cytosolic fraction to the particulate fraction, indicating a possible role of NNK in the signal transduction pathway. The present study provided an evidence that NNK in the smoking may be associated with epithelial origin cancer such as oral and nasal cavity cancers. In addition, this study suggested that altered expression of extracellular matrix and PKC may play an important role in the carcinogenic mechanism of NNK.

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ORTHODONTIC TREATMENT OF AN IMPACTED MANDIBULAR FIRST MOLAR USING MINIPLATE AS A SKELETAL ANCHORAGE: A CASE REPORT (Miniplate를 골격성 고정원으로 이용한 매복된 하악 제1대구치의 교정치료 증례)

  • Jang, Yoon-Hyoung;Kim, Eun-Young;Kim, Kwang-Chul;Park, Jae-Hong;Lee, Baek-Soo;Choi, Sung-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.37 no.2
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    • pp.246-251
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    • 2010
  • Impactions can occur because of malpositioning of the tooth bud or obstruction in the path of eruption. However, the exact mechanism is still unknown. The impaction of mandibular first molar is rare with prevalence rates of 0.01~0.25%, but it is important to deimpact the tooth as soon as possible to avoid complications such as dental caries, root resorption, and periodontal problems on the adjacent teeth. Several biomechanical strategies have been proposed for uprighting mesially tipped mandibular first molars. However, most of these have had problems with movement of the anchorage unit because of the reciprocal force. The recent development of skeletal anchorage system(SAS) allows direct application of precise force systems to the target tooth or segment, producing efficient tooth movement in a short time. In this case, an impacted mandibular left first molar with dilacerated roots was treated with a miniplate, which provided skeletal anchorage to upright the tooth. The miniplate was installed in the mandibular ramus, and 10 months after the application of orthodontic force, the impacted tooth was exposed in the oral cavity and uprighted. At this point, the mandibular left first molar was included in the orthodontic appliance with fixed mechanotherapy, the tooth could achieve a normal occlusion. Therefore, the use of SAS simplified the orthodontic procedures and reduced the orthodontic treatment period, and had few side effects.

Long-term Bias of Internal Markers in Sheep and Goat Digestion Trials

  • De Carvalho, Gleidson Giordano Pinto;Garcia, Rasmo;Vieira Pires, Aureliano Jose;Silva, Roberio Rodrigues;Detmann, Edenio;Oliveira, Ronaldo Lopes;Ribeiro, Leandro Sampaio Oliveira
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.1
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    • pp.65-71
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    • 2013
  • Two digestion trials, one with sheep and another with goats, were conducted to evaluate the long-term bias (LTB) of the indigestible dry matter (iDM), indigestible neutral detergent fiber (iNDF) and indigestible acid detergent fiber (iADF) internal markers. The study used eight Santa In$\hat{e}$s castrated male sheep (average body weight of 16.6 kg) distributed in two $4{\times}4$ Latin squares and eight Saanen castrated male goats (average body weight of 22.6 kg) distributed in two $4{\times}4$ Latin squares. The experiments were conducted simultaneously, and the animals were housed in 1.2 $m^2$ individual pens with wood-battened floors equipped with individual feeders and drinkers. The animals received isonitrogenous diets that were offered ad libitum and contained 14% crude protein and 70% sugar cane (with 0, 0.75, 1.5 or 2.25% CaO, in natural matter percentage), corrected with 1% urea and 30% concentrate. The experiment consisted of four experimental periods of 14 d each, with the feed, leftovers and feces sampled on the last four days of each period. The marker concentrations in the feed, leftovers and fecal samples were estimated by an in situ ruminal incubation procedure with a duration 240 h. The relationship between the intake and excretion of the markers was obtained by adjusting a simple linear regression model, independently from the treatment (diets) fixed effects and Latin squares. For both the sheep and goats, a complete recovery of the iDM and iNDF markers was observed (p>0.05), indicating the absence of LTB for these markers. However, the iADF was not completely recovered, exhibiting an LTB of -9.12% (p<0.05) in the sheep evaluation and -3.02% (p<0.05) in the goat evaluation.

A Study on the Predictability of Hospital's Future Cash Flow Information (병원의 미래 현금흐름 정보예측)

  • Moon, Young-Jeon;Yang, Dong-Hyun
    • Korea Journal of Hospital Management
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    • v.11 no.3
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    • pp.19-41
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    • 2006
  • The Objective of this study was to design the model which predict the future cash flow of hospitals and on the basis of designed model to support sound hospital management by the prediction of future cash flow. The five cash flow measurement variables discussed in financial accrual part were used as variables and these variables were defined as NI, NIDPR, CFO, CFAI, CC. To measure the cash flow B/S related variables, P/L related variables and financial ratio related variables were utilized in this study. To measure cash flow models were designed and to estimate the prediction ability of five cash flow models, the martingale model and the market model were utilized. To estimate relative prediction outcome of cash flow prediction model and simple market model, MAE and MER were used to compare and analyze relative prediction ability of the cash flow model and the market model and to prove superiority of the model of the cash flow prediction model, 32 Regional Public Hospital's cross-section data and 4 year time series data were combined and pooled cross-sectional time series regression model was used for GLS-analysis. To analyze this data, Firstly, each cash flow prediction model, martingale model and market model were made and MAE and MER were estimated. Secondly difference-test was conducted to find the difference between MAE and MER of cash flow prediction model. Thirdly after ranking by size the prediction of cash flow model, martingale model and market model, Friedman-test was evaluated to find prediction ability. The results of this study were as follows: when t-test was conducted to find prediction ability among each model, the error of prediction of cash flow model was smaller than that of martingale and market model, and the difference of prediction error cash flow was significant, so cash flow model was analyzed as excellent compare with other models. This research results can be considered conductive in that present the suitable prediction model of future cash flow to the hospital. This research can provide valuable information in policy-making of hospital's policy decision. This research provide effects as follows; (1) the research is useful to estimate the benefit of hospital, solvency and capital supply ability for substitution of fixed equipment. (2) the research is useful to estimate hospital's liqudity, solvency and financial ability. (3) the research is useful to estimate evaluation ability in hospital management. Furthermore, the research should be continued by sampling all hospitals and constructed advanced cash flow model in dimension, established type and continued by studying unified model which is related each cash flow model.

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Effects of hydrogen addition during sputtering on the electrical properties of AIN insulating films for MIS device application (스퍼터링시 수소첨가가 MIS소자용 AIN절연박막의 전기적특성에 미치는 영향)

  • Kwon, Jung-Youl;Lee, Hwan-Chul;Lee, Heon-Yong
    • Transactions of the Korean hydrogen and new energy society
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    • v.10 no.1
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    • pp.59-69
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    • 1999
  • AlN thin films were fabricated by reactive sputtering for the application of MIS devices with Al/AlN/Si structure. It has investigated the surface morphology change, I-V characteristics, C-V characteristics, and chemical composition of AlN films with the intriducing time of hydrogen on the fixed deposition condition(RF power: 150W, sputtering pressure: 5mTorr, flow rate ratio of $Ar/N_2=1$, hydrogen concentration: 5%). By addition of the hydrogen the deposition rate decreased drastically whereas the surface morphology changed little. It has been found from the analysis of I-V and C-V characteristics curves that the films deposited with hydrogen addition in initial stage had lower leakage current density, lower flat band voltage and hystersis profile when compared with those with hydrogen addition in last stage. The oxygen concentration in AlN films decreased with addition of hydrogen gas, which suggesting a profitable role in the insulation and C-V characteristics of AlN films.

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