• 동의생리병리학회지
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• 제24권2호
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• pp.197-205
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• 2010

The association between five limpness(五軟), five stiffness(五硬), five retardation and disease have been repeatedly shown in patient. However, comparative study has been rare. This study arrange disease, which answer to five limpness, five stiffness, five retardation and classify by epiologic diagnosis. We search for scientific journals, medical college texts, theses of a degree and collect case reports. In this study we found that the five retardation(N=56) is showing numerous more than the others. The five stiffness(N=14) is showing rare than the five limpness(N=29). The five limpness is overlapping more than 90% with five retardation. and the five stiffness is overlapping 80% with five retardation. Symptom of five limpness, five stiffness, five retardation is coming out independent and overlapping each others. And generally it accompanies with abnormality in central nervous system.

• 동의신경정신과학회지
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• 제16권2호
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• pp.25-34
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• 2005

Background and Objectives There was no clinical data except literary study on mutual correlation with autistic disorder in Western medical diagnosis and five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) in Oriental medical diagnosis. This study was performed to investigate the correlation of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) to the children with autistic disorder and to set the time table for clinical diagnosis of developmental retardation by making a comparative study of normal developmental children so we can treat the children with autistic disorder in good time. Method We made the comparative study of interview sheets recorded by parents of total 163 children who were diagnosed as autistic disorder who visited HaeMa Oriental Medical Clinic with interview sheets recorded by parents of generally accepted normal developmental children(263) and then we took statistics. Results : 1. There was significant correlation with speech and walking among five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) in autistic disorder statistically and clinically in comparison with normal children. 2. There wasn't significant correlation with growth time of tooth among five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) on diagnosis of autistic disorder in comparison with normal children. 3. There was significant correlation with retardation of times going to toilet by oneself (it does not consist in five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲).) in both of autistic disorder. Conclusion Autistic disorder was significantly correlated with the faculty of speech(語遲), retardation in walking out(行遲) of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲). We need to concrete the index of diagnosis, because it is so difficult to measure times and register retardation in tooth eruption(齒遲), retardation in hair-growing(髮遲), debility of neck and nape(頭項軟), flaccidity of extremities(手軟) and flaccidity of muscle(肌肉軟). And we can also use times going to toilet by oneself as one of diagnostic criteria because of its significant correlation. It is required to make early diagnosis of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) using these criteria, and to treat them early by oriental medicine.

• 대한한방소아과학회지
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• 제24권2호
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• pp.1-12
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• 2010

Objectives Taking detailed patient history helps earlier diagnosis and treatment of developmental disability. In this study we analyzed the clinical questionnaire to find out the clinical characteristics of those with five-retardation, five-limpness, or five-stiffness. Methods The data was collected from 484 children under the age of six who have visited H oriental medicine clinic for developmental delay. The clinical questionnaire was filled out by their parents and the data was analyzed statistically. Results 436 children showed symptoms of five-retardation, 90 children suffered from five-stiffness, 54 children showed five-limpness and 7 children suffered from five-stiffness and five-limpness complex. Generally, boys had higher chance to show disease symptoms than the girls (2.32:1) and 40 children (8.26%) reported family history of developmental disability. Cerebral palsy ranks the most common familial disease, followed by developmental delay, mental retardation, autistic disorder and language disorder. Among the children we have studied, 285 children (63.19%) showed delayed unassisted walk while 192 children (42.57%) had language disorder. Also, 138 children (28.51%) had both walk and language disorders. The children in this study also showed delayed toilet training and half of them had little stranger anxiety when they were infants. It was also found that 120 children (24.79%) experienced epilepsy. This study reaffirmed that low birth weight, premature birth, and suffocation are major risks causing neurological damage. Conclusions They had history which including family history, problems at birth, epilepsy, face recognition, muscle tone disorder, delayed walking without assistance, language ability, and toilet training.

• 대한한방소아과학회지
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• 제18권1호
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• pp.165-177
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• 2004

Objective : The purpose of this study is to report a pediatric patient combined some peculiar diseases of nervous system in childhood. Methods : The patient with preceding five kinds of retardation developed five kinds of flaccidity and five kinds of spasticity after chronic infantile convulsion. We treated the progress of her condition, measured spasticity of both leg by MAS(Modified Ashworth Scale). Results and Conclusion: The general condition of patient, symptoms of five kinds of flaccidity and MAS grade of both leg spasticity had been improved. And so this study requires further studies about peculiar diseases of nervous system in childhood.

• 대한음성학회지:말소리
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• 제60호
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• pp.85-96
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• 2006

The aim of the present study was to investigate a simile comprehension of children with and without mental retardation. Thirteen children with mental retardation and ten normal children with matched receptive vocabulary ability participated in the study. They were between five and eight years old in the age of receptive vocabulary. Fourteen picture plates were used and each plate consisted of three pictures. The findings were as fellows. First, children with mental retardation made significantly more errors than normal children in the comprehension of simile. Second, mental retarded children and normal children did not have a significant correlation between receptive vocabulary development and comprehension of simile. Finally, on simile interpretation type, children with mental retardation were likely to think a tenor into a vehicle because they failed to recognize the syntactic structure of simile, 'A is like B'. Thus, It is important to teach mental retarded children the syntactic structures of simile and to provide them with a variety of experience as well as to let them know an exact meaning of words.

• 대한장애인치과학회지
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• 제11권2호
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• pp.76-80
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• 2015

장애인의 보건 수준이 높아지면서 치료보다는 예방의 관점에서의 구강 관리가 중요해지고 있다. 본 증례에서 소개된 다섯 명의 지적 장애를 지닌 환자들을 triazolam을 이용하여 경구 투여하여 치료하였다. Triazolam을 이용한 진정법은 장애인의 정기적인 구강 관리의 한 대안으로 고려해볼 수 있겠다.

• 한국광학회지
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• 제25권5호
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• pp.262-272
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• 2014

두 개의 회전하는 사분파장판을 가진 타원편광분석기에서 광학계가 오차를 포함하지 않는 경우와 5가지의 체계적 오차(두 개의 사분파장판의 정렬오차와 지연오차, 검광판의 정렬오차)를 포함하는 경우에 측정신호를 핏팅하여 구한 퓨리어 계수와 뮬러매트릭스와의 관계를 분석하였다. 5가지 체계적 오차를 포함하는 경우 전산모사를 이용해 비교 분석한 결과 사분파장판의 지연 오차가 정렬오차보다 뮬러매트릭스 대각선 요소에 야기하는 오차가 더 크다는 것을 찾아내었다. 각속도의 회전비를 1:5로 선택시 첫 번째 사분파장판의 초기 정렬오차와 두 번째 사분 파장판의 초기 정렬오차가 뮬러 매트릭스에 야기하는 오차가 같다는 것을 전모사를 통해 찾아 내었다. 5가지 체계적인 오차를 전산모사를 통해 분석한 결과 검광판의 정렬오차(${\epsilon}_5$)가 야기하는 뮬러 매트릭스 오차와 사분파장판의 정렬오차(${\epsilon}_3$, ${\epsilon}_4$)가 야기하는 뮬러 매트릭스 오차를 비교하면 대각선 요소($m_{22}$와 $m_{33}$)의 상대 오차는 0.18%이며 비 대각선요소($m_{23}$와 $m_{32}$)는 2배 차이가 남을 찾아내었다. 이 결과들을 활용하여 측정대상 물질의 보다 정확한 뮬러매트릭스를 얻을 수 있다.

• 대한본초학회지
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• 제29권5호
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• pp.31-38
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• 2014

Objectives : Egg yolk is composed of various important chemical substances for human health. A calcium shortage causes the growth retardation on the body growth. In this study, we examined the therapeutic effects of calcium, vitamin D and egg yolk peptide (EYP) treatment on the retardation of the longitudinal bone growth induced by low-calcium diet in adolescent rats. Methods : Low calcium diets were administrated for 15 days. During the last five days, calcium and/or vitamin D and/or EYP were administrated. The body weights, longitudinal bone growth rates, the heights of growth plates, and bone morphogenetic protein (BMP)-2 and insulin-like growth factor (IGF)-1 expressions were measured using histochemical analysis. Results : Low calcium diets caused the significant reduction in body weight gains and the longitudinal bone growth. The heights of growth plates and the expressions of BMP-2 and IGF-1 showed the impairment of body growth as well. Calcium and/or vitamin D administration could not significantly increase the longitudinal bone growth. However, calcium, vitamin D, and EYP administration significantly increased the bone growth, the growth plate height, and BMP-2 and IGF-1 expressions. Conclusions : These results suggest that EYP enhances the longitudinal bone growth in the calcium and/or vitamin D deficiency and it could be a promising agent for the treatment of children suffering from malnutrition.

• Nuclear Engineering and Technology
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• 제25권3호
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• pp.447-456
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• 1993

중저준위 방사성폐기물처분장 인공방벽의 핵종유출 저지능을 평가할 수 있는 단순 모델이 제안되었다. 이 모델은 현재 우리나라에서 제안되고 있는 처분장 개념을 고려하여 고안되었으며, 인공방벽의 설계에 적합한 설계 기준 유출 과 인공방벽 성능평가에 적합한 현실적 유출 두 가지 경우를 다루고 있다. 모델의 유용성을 보이기 위해 화학적 특성이 다른 다섯 핵종에 대해 모의 계산을 수행하고 그 결과를 분석하였다.

• 생명과학회지
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• 제9권6호
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• pp.704-708
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• 1999

This research was carried out for evaluating diagnostic value of antibody test in Fragile X syndrome. In antibody test of control individuals and carriers with a premutation, FMRP were detected in the lymphocytes, whereas the lymphocytes of male Fragile X syndrome patients were devoid of FMRP. Five Fragile X syndrome male patient, two Fragile X syndrome female patients, three carriers were diagnosed by southern blot. Five boys who were diagnosed as the patients by antibody test were turned out full mutation and having multiple smear beside normal single band. However, fragile site of X chromosome was not expressed in Fragile X syndrome patients by chromosome analysis. These results showed that antibody test was a fast and simple method, but the diagnostic power was "perpect" for males, whereas the results were less specific for females.r females.