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A Case of Recurrent Ventricular Tachycardia after Pimozide and Haloperidol Overdose (Pimozide와 Haloperidol 과량 복용 후 반복적으로 발생한 심실 빈맥 1례)

  • Jung, Jin-Hee;Jang, Hye-Young;Eo, Eun-Kyung
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.1
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    • pp.67-70
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    • 2005
  • Pimozide and haloperidol are typical antipsychotics. They share a similarity in pharmacotherapeutic and adverse effect profiles. Cardiovascular effects may be seen as alterations in heart rate, blood pressure, and cardiac conduction. Conduction disturbances may occur ranging from asymptomatic prolongation of the QT interval to fatal ventricular arrhythmia. So in the case of anti psychotics overdose, the patient must be carefully monitored by continuous electrocardiography (ECG). We experienced a 34-year-old woman of schizophrenia with recurrent ventricular tachycardia after pimozide and haloperidol overdose. Initially she was slightly drowsy, however her ECG showed normal sinus rhythm. After 6 hours on emergency department entrance, her ECG monitoring showed ventricular tachycardia and we successfully defibrillated. There were five times events of ventricular arrhythmia during the in-hospital stay. She was discharged 5 days later without any other complications.

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Mushrooms: An Important Source of Natural Bioactive Compounds

  • Ha, Ji Won;Kim, Juhui;Kim, Hyunwoo;Jang, Wonyoung;Kim, Ki Hyun
    • Natural Product Sciences
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    • v.26 no.2
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    • pp.118-131
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    • 2020
  • Mushrooms are known for their various attributes in the fields of nutrition and therapeutics. With exceptional taste, aroma, and nutritional value, they are considered 'functional food'-improving health and providing nutritional benefits to the body. Mushrooms have also been widely applied therapeutically as they possess diverse bioactive compounds known as secondary metabolites. These secondary metabolites demonstrated diverse biological properties such as anticancer, anti-diabetic, immunomodulatory, antimicrobial, anti-inflammatory, antiviral, anti-allergic, and antioxidative activities. This review presents bioactive compounds from the field of mushroom metabolite research and discusses important findings regarding bioactive compounds identified during the last five years (2015 - 2019).

Taxonomic Studies on Brackish Copepods in Korean Waters. I Redescription of Tortanus dextrilobatus Chen and Zhang, 1965 from Korean Waters, with Remarks on Zoogeography of the subgenus Eutortanus (한국산(韓國産) 기수성(汽水性) 소각류(燒脚類) 분류학적(分類學的) 연구(硏究) 1. 한국(韓國)에 있어서 미기록종(未記錄種) Tortanus dextrilobatus Chen and Zhang, 1965 기재(記載)와 Eutortanus 아속(亞屬)의 지리분포(地理分布)에 대하여)

  • OHTSUKA, SUSUMU;YOON, YANG HO;ENDO, YUKIHIRO
    • 한국해양학회지
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    • v.27 no.2
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    • pp.112-122
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    • 1992
  • The calanoid copepod Tortanus (Eutortanus) dextrilobatus Chen and Zhang, 1965, which had been recorded only from South China, is redescribed from brackish waters in South Korea. The diagnosis of the little known subgenus Eutortanus is presented hear. The zoogeography of five species of Eutortanus is also discussed.

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Psittacine Beak and Feather Disease, Budgerigar Fledgling Disease and Aspergillosis in an African Grey Parrot (Psittacus erithacus)

  • Kang, Hyo-Min;Jang, Hye-Jin;Seo, Myung-Kyo;Lee, Jong-Won;Na, Ki-Jeong
    • Journal of Veterinary Clinics
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    • v.34 no.4
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    • pp.310-312
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    • 2017
  • A five-month-old African grey parrot was presented with alopecia, yellowish diarrhea, depression, and paralysis in the veterinary medical center, Chungbuk National University. The patient died 3 h later after hospitalization. For the accurate diagnosis, necropsy was performed and fungi were detected in the air sac. PCR was done for the viral detection which caused the alopecia, and for the species identification of fungi. Final diagnosis was a multi infection with avian circoviruses that caused psittacine beak and feather disease (PBFD), avian polyomavirus cause budgerigar fledgling disease (BFD), and Aspergillus fumigatus. This is the first report of a multi infection in South Korea.

The Relationship of HOME to Preschool Children's Developmental Levels (가정환경 자극검사(HOME)와 학령전 아동의 발달 수준과의 관계)

  • Jang, Young Ae;Suh, Yong Sun
    • Korean Journal of Child Studies
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    • v.4
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    • pp.1-10
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    • 1983
  • This study examined the characteristics of the relationship of home environment variables and preschool children's intelligence, learning readiness and socio-emotional developments. The subjects of this study were 63 children at age five and their mothers. Instruments included the children's intelligence test, preschool inventory for learning readiness, the socio-emtional rating scale and the inventory of HOME. The data of the present study were analyzed by the statistical methods of Pearson's product-moment correlation coefficient and step-wise multiple regression analysis. The kinds of HOME variables that significantly predict children's intelligence were "need gratification and avoidance of restriction" "quality of language environment" "play materials" "aspects of physical environment" "organization of stable and predictable environment". The variables that significantly predict children's socio-emotional developments were "breath of experience" "fostering maturity and independence" "developmental stimulation". All of the HOME variables were not significantly predict children's learning readiness. The kinds of HOME factors that significantly predict children's intelligence were factor II and factor III. Factor I predicted children's socio-emotional developments significantly. All of the HOME factors were not significantly predicted children's learning readiness.

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The Effects of Science Activities using Nonfiction Literature on Preschool Children's Scientific Process Skills, Attitudes and Concepts (논픽션도서를 활용한 과학 활동이 유아의 과학적 탐구능력과 태도 및 개념에 미치는 영향)

  • Jang, Yeon-Hee;Chung, Chung-Hee
    • Korean Journal of Child Studies
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    • v.31 no.5
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    • pp.167-191
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    • 2010
  • The purpose of this study is to examine how science activities using nonfiction literature affectspreschool children's scientific process skills, attitudes and concepts. For the purposes of this study, two classes, consisting of four and five-year-old children in a kindergarten located in D city were selected. One class was designated as the experimental group and the other as the control group. The experimental group performed science activities using nonfiction literature, while the control group did not. Thisexperimental study was conducted over the course of 8 weeks. Analysis of data was performed by ANCOVA. The results of the posttest indicated that the experimental group which performed science activities using nonfiction literature showed an improvement in their process skills, scientific attitudes and scientific concepts compared with the control group.

Design of a 2.5V 2.4GHz Single-Ended CMOS Low Noise Amplifier (2.5V, 2.4GHz CMOS 저잡음 증폭기의 설계)

  • Hwang, Young-Sik;Jang, Dae-Seok;Jung, Woong
    • Proceedings of the IEEK Conference
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    • 2000.06e
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    • pp.191-194
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    • 2000
  • A 2.4 GHz single ended two stage low noise amplifier(LNA) is designed for Bluetooth application. The circuit was implemented in a standard digital 0.25 $\mu\textrm{m}$ CMOS process with one poly and five metal layers. At 2.4 GHz, the LNA dissipates 34.5 mW from a 2.5V power supply voltage and provides 24.6 dB power gain, 2.85 dB minimum noise figure, -66.3 dB reverse isolation, and an output 1-dB compression level of 8.5 dBm.

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Development of Safety Competences, Behavioral Indicators and Measuring Methods for Preventing Human-Error in Nuclear Power Plants: A Preliminary Study (원전 인적오류 예방을 위한 안전 역량, 행동 지표 및 측정 방법 개발: 예비 연구)

  • Moon, Kwangsu;Kim, Sa Kil;Lee, Yong-Hee;Jang, Tong Il
    • Journal of the Korean Society of Safety
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    • v.31 no.1
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    • pp.132-138
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    • 2016
  • The purpose of this study was to develop safety competences, a set of behavioral indicators of each competence and measuring methods of behavioral indicators for preventing human error of nuclear power plants(NPPs). The safety competences and behavioral indicators were derived from the five steps consisted of derivation of preliminary competence items through literature review, content analysis, interview(FGI, BEI), examination of content validity and decision making of final indicators. The results showed that 13 core safety competences and 35 behavior indicators were derived finally. In addition, the methods of measuring safety competences or behavioral indicators such as Behaviorally Anchored Rating Scale (BARS), Behavior Observation Scale (BOS) were developed and suggested.

An Assessment of Bonding Shear Performance of Ultra-high-performance Concrete Regarding Interface Treatment (표면처리방법에 따른 초고성능 콘크리트의 전단부착성능 평가 연구)

  • Jang, Hyun-O;Park, Jin-Ho;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2016.10a
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    • pp.81-82
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    • 2016
  • The present study aims to derive optimal interface treatment conditions for emulating a monolithic construction. The joints in this construction are formed through the bonding shear evaluation method during the placement of ultra-high-performance concrete (UHPC) and normal strength concrete (NSC). The evaluation items include push-off tests for homogeneous UHPC + UHPC and heterogeneous NSC + UHPC. The experimental samples comprised a monolithic placement as the baseline, two levels for the separated placement according to the compression strength of concrete, and five levels for the interface treatment. The increase in the number of grooves and their cross-sectional areas only slightly influenced the bonding shear performance. The optimal interface treatment method for the homogeneous UHPC + UHPC construction grooves was at least 30mm. The heterogeneous NSC + UHPC construction should utilize waterjet roughening to expose the aggregate for the increased roughness.

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Atomization Characteristics of the High Speed Rotating Injection System with Single Column Orifice (단열식 오리피스를 적용한 고속회전 분무노즐의 미립화 특성)

  • Jang, Seong-Ho;Choi, Seong-Man
    • Journal of ILASS-Korea
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    • v.14 no.3
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    • pp.97-102
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    • 2009
  • The spray characteristics of the high speed rotating fuel injection system were studied. The five variants of rotating fuel nozzle were used by spray test. The diameter of single column injection orifices are varied from 1 mm, 2 mm, 3 mm, 4 mm and 5 mm. We constructed high speed rotating test rig and measured droplet size by PDPA (Phase Doppler Particle Analyzer) system. Also spray was visualized by using high speed camera. In the test results, we could understand that length of liquid column from the injection orifice is mainly controlled by the rotational speeds. SMD is decreased with increasing injection orifice diameter and rotational speeds. Furthermore, from the comparison to the theoritical calculation, we confirmed that SMD is influenced by the liquid film thickness which is formed inner surface of injection orifice.

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