• Genomics & Informatics
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• 제19권4호
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• pp.38.1-38.7
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• 2021

Kawasaki disease (KD) is an acute pediatric vasculitis that affects genetically susceptible infants and children. To identify coding variants that influence susceptibility to KD, we conducted whole exome sequencing of 159 patients with KD and 902 controls, and performed a replication study in an independent 586 cases and 732 controls. We identified five rare coding variants in five genes (FCRLA, PTGER4, IL17F, CARD11, and SIGLEC10) associated with KD (odds ratio [OR], 1.18 to 4.41; p = 0.0027-0.031). We also performed association analysis in 26 KD patients with coronary artery aneurysms (CAAs; diameter > 5 mm) and 124 patients without CAAs (diameter < 3 mm), and identified another five rare coding variants in five genes (FGFR4, IL31RA, FNDC1, MMP8, and FOXN1), which may be associated with CAA (OR, 3.89 to 37.3; p = 0.0058- 0.0261). These results provide insights into new candidate genes and genetic variants potentially involved in the development of KD and CAA.

• 한국약용작물학회지
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• 제9권1호
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• pp.33-39
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• 2001

질소비료를 $3{\sim}7$회 분시하여 옥로차의 수량 및 품질을 분석한 결과는 다음과 같다. 5회 분시가 타처리에 비해 생육과 수량이 많고 타처리에 비해 총질소, 총아미노산, 비타민C 함량이 약간 많았으며 탄닌, 카페인, 엽록소, 총유리당 함량은 3회분시를 제외하고 $4{\sim}7$회 분시에서 거의 차이가 없었다. 지방산 함량은 $2,888{\sim}2,933mg/100g$이었고, 특히 5회 분시에서는 oleic acid, linoleic acid, linolenic acild 함량이 가장 많았다. 옥로차 감칠맛 성분인 theanine을 포함해 16종이 아미노산을 분리 정량한 결과 5회 분시가 타처리에 비해 theanine 함량이 $72{\sim}513mg/100g$더 많았다. 관능평가에서 3회 분시가 80.2점으로서 다른 처리보다 낮았고, 5회 처리가 84.7점으로 가장 높았다. 결론적으로 5회 분시처리가 다른처리에 비해 수량도 양호하고 차 품질도 우수하여 옥로차의 적정 분시첫수라고 생각된다.

• Mycobiology
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• 제45권1호
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• pp.1-8
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• 2017

Despite the huge worldwide diversity of Trichoderma (Hypocreaceae, Ascomycota), only about 22 species have been reported in Korea. Thus, between 2013 and 2015, soil-derived Trichoderma spp. were isolated to reveal the diversity of Korean Trichoderma. Phylogenetic analysis of translation elongation factor 1 alpha gene was used for identification. Among the soil-derived Trichoderma, Trichoderma albolutescens, T. asperelloides, T. orientale, T. spirale, and T. tomentosum have not been previously reported in Korea. Thus, we report the five Trichoderma species as new in Korea with morphological descriptions and images.

• 한국조경학회지
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• 제33권5호통권112호
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• pp.104-113
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• 2005

This landscape design proposal was presented for a competition for mixed-use development project by project financing in Asan Baebang which was held by the Korea National Housing Corporation in July of 2005. The site is a center of Asan Baebang New Town Development District and has a commercial area of $57,929m^{2}$. Design guidelines and judging criteria of this competition were to build a symbolic center and cultural core for district, to elevate positive image and identity of Asan New Town by attractive place making, to link with separated block in the site and regional context, and to make environmentally sustainable design by creating an attractive waterfront of Jang Jae stream passing through the site. This is the most important condition for the design. Therefore, the authors developed design concept and strategy within the guidelines and this conditions. The schema of the design was introduced by the water in the site. To evolve design concept, we reinterpreted water and context in the site combining with landscape design strategy. So the proposal set the main design concept as 'all that is solid melt into water' as if Marshall Berman said. By doing that, design concept of the proposal evolved as follows: 'extension' of water and greer, 'a joint' of space,'newness' of experience, 'breath' of consensus with each other. The spatial concept of this project was developed by expressing five theme spaces; eco zone, entertainment zone, art zone, culture zone, leisure zone. These theme spaces were consecutively placed along the pedestrian path and to consists of vertical layer in each level and diverse design technique and spatial effects are used.

• Journal of Acupuncture Research
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• 제24권5호
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• pp.229-240
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• 2007

Objectives : The purpose of this study is to report the image changes of five cases of Cervical intervertebral disc Herniation after Oriental medicine Treatment. Patient & Methods : We examined 5 patients with Cervical intervertebral disc Herniation (HIVD of C-spine) who showed changes on MRI images before/after the treatment among HIVD of C-spine patients who visited Cervical Spine center, Jaseng Hospital of Oriental Medicine from March, 2006 to May, 2007. Results & Conclusions : In this study, the first MRI examination of HIVD of C-spine patients was performed at the first visit and re-examination of MRI was done after the treatment. We assessed clinical symptoms by using Numerical rating scales(NRS). In each case, the size of the disc herniation was considerably reduced in MRI image. NRS was also reduced significantly.

• 인간식물환경학회지
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• 제23권1호
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• pp.67-75
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• 2020

The purpose of this study was to develop an effective horticultural activity program for the vocational rehabilitation of people with mental disabilities. The subjects of this study were seven persons with mental disabilities in the vocational rehabilitation team of a public health center located in G city, Gyeongsangbuk-do. A total of 10 horticultural programs were held from October 10 to December 11, 2018. Five programs were selected among those that were easy for the persons with mental illness to handle and their preference was high. In each session, the same task was repeated 10 times and finally changes in hand functions and working speed were measured. As a result, the assembly task of the Purdue Pegboard test was 23.6 (SD = 10.5) before the program, 26.6 (SD = 11.5) after planting, 27.7 (SD = 12.2) after wrapping pots, and 28.0 (SD = 13.9) after making mini flower baskets, 26.9 (SD = 12.0) after wrapping a single flower, and 29.1 (SD = 11.9) after making corsages. There was a significant difference between the five programs (p = .016). As a result of measuring the time taken to produce the same 10 products, the average planting time was 9.9 (SD = 4.0) minutes in the first class and 6.0 (SD = 2.3) minutes in the second class (p = .018), and making mini flower baskets was reduced from 35.2 (SD = 10.1) minutes to 21.0 (SD = 7.7) minutes (p = .018), wrapping a single flower from 23.3 (SD = 7.9) minutes to 16.2 (SD = 7.3) minutes (p = .043), and making corsages from 53.6 (SD = 15.9) to 40.8 (SD = 16.8) minutes (p = .043). The working time was significantly shortened in the second class compared to the first class. The class for wrapping pots was shortened from 52.7 (SD = 11.7) to 49.6 (SD = 17.8) minutes, but there was no significant difference (p = .398).

• 대한한의학원전학회지
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• 제28권1호
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• pp.111-125
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• 2015

Objectives : The objectives of this study is to provide the theoretical basis to cure and prevent mental disease by translating and considering Benshen chapter in LingShu. Methods : First, I translate the contents of "Benshen" chapter in LingShu paragraph by paragraph. Second, I consider the contents of Benshen chapter in LingShu. Third, after considering each paragraph of Benshen chapter in LingShu, I think the relation of each paragraph and picture to myself Benshen chapter. Results and Conclusions : 1. Heart(心) appeared in Benshen chapter mediates the action of 'JeongSinHonBaek(精神魂魄)' and 'UiJiSaRyeoJi(意志思虑智)'. 2. 'UiJiSaRyeoJi(意志思虑智)' appeared in Benshen chapter means the process of the maturity of thought. 'Jeong(精)' which has a 'water(水), sink(沈), silent(靜)' image gets involved in the development from 'Ui(意)' to 'Ji(志)', because its process means the thought is deepening. 'Hon(魂)' which has a 'wind(風), cloud(雲), change(變)' image gets involved in the development from 'Ji(志)' to 'Sa(思)', because its process means the change of the thought. 'Sin(神)' which has a 'fire(火), bright(明), move(動)' image gets involved in the development from 'Sa(思)' to 'Ryeo(慮)', because its process means the expansion the horizon of the cognition. 'Baek(魄)' which has a 'metal(金), firm(剛), decide (決)' image gets involved in the development from 'Ryeo(慮)' to 'Ji(智)', because its process means the wise response to real world. 3. If one is immersed in one emotion and cannot escape from it, the functional change of Gi(氣) due to its emotion harms five spirits which move in the opposite direction and causes mental physical symptoms and has a possibility to die in the season which inhibit each five organs. 4. Five spirits(五神) acts based on 'HyeolMaekYeongGiJeong(血脈營氣精)' and in the symtoms caused by deficiency and excess of five organ Gi(五藏氣), symptoms of liver and heart appear in emotion and symptoms of spleen lung kidney appear in body. 5. Benshen chapter highlights the importance of checking 'Sin(神)' and 'Gi(氣)' treating a patient with acupuncture and mentioning the importance of observing deficiency and excess of five organ Gi(五藏氣) in the last paragraph means 'Sin(神)' and 'Gi(氣)' are inseparably related.

• 공연문화연구
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• 제33호
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• pp.329-354
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• 2016

협률랑(協律郞)은 궁중에서 의례(儀禮)를 행할 때 음악의 연주와 정지시점을 알려주던 직책이다. 유교의 영향을 받아 궁중에 오례(五禮) 체제로 범주화 되고 실행되면서부터 협률랑의 존재가 드러난다. 유가에서는 예(禮)와 악(樂)을 중시했고 이와 같은 흐름이 궁중 오례(五禮)로 연계되어 주요의례에 음악이 수반되었기 때문에, 궁중 의례의 진행 상황에 따라 음악의 삽입 여부를 알려줄 매개자가 요청되는 실정이었다. 궁중의 의례와 음악의 조화로운 구현을 위해 협률랑은 필수불가결한 존재였던 것이다. 우리나라에서는 협률랑이 고려시대부터 등장하며 조선시대에도 지속적으로 존재하였다. 조선시대의 협률랑은 봉상시(奉常寺)에서 전담되다가 전악(典樂)에게 잠시 일임된 적도 있었지만 최종적으로는 장악원(掌樂院) 관원이 맡는 것으로 규정되었다. 장악원 관원 중에서도 주로 장악원 정(掌樂院 正)이 그 역할을 수행했지만, 장악원 첨정(僉正)과 장악원 주부(主簿)도 현실적인 여건에 따라 수시로 차출되곤 하였다. 장악원 정, 첨정, 주부 등 역대 협률랑 역임자들의 공통 사항은 모두 당하관(堂下官)이었다는 점이었다. 당하관은 정책 결정에 참여하지 못하는 근본적인 한계를 지닌 관료였으며, 권한이 미약했던 실무자였다. 이는 궁중 행사에 동원되었던 많은 이들이 맡았던 각각의 다양한 직책 중 협률랑이 궁중의례에서 점하던 위상을 드러낸다. 한편 의례 집행 여건이나 의례 자체의 성격에 따라 장악원 관원 대신 계라선전관(啓螺宣傳官), 무신겸선전관(武臣兼宣傳官), 여집사(女執事) 등도 협률랑으로 유연하게 활용되어 의례와 음악 집행에 흠결사항이 없도록 조치되었다. 협률랑의 활동은 악대가 수반된 대부분의 의례에서 휘를 세우거나 눕히는 행동으로 압축된다. 휘는 깃발의 하나로, 성곽 영토 지역 등을 표시하던 시각 장치의 일종인데, 사냥할 때나 군대에서는 진퇴를 알리는 신호 체계로도 사용되다가, 의례와 음악을 조율하는 용도로까지 그 쓰임이 확장되었다. 그런데 밤에는 휘가 보이지 않으므로 조촉(照燭)으로 대신하거나, 때로는 금고기(金鼓旗)를 대용품으로 쓰기도 하였다. 그리고 협률랑의 명칭은 궁중연향의 경우 의물의 명칭을 빌려와 거휘차비, 조촉차비로 기록되기도 하였다. 협률랑의 자리는 서계(西階) 위 서쪽 가까이 동향(東向)한 상태로 배치되었는데, 의례 집행 장면이 잘 보이면서 악대와 가까운 지점이었다. 그 역할의 특성을 고려하여 의례의 공간과 음악의 공간이 함께 파악되는 위치에 배치되었다. 또한 행사를 대비한 예행 연습, 습악(習樂), 악대 배치, 음악 연주 속도 조절, 악곡(樂曲) 누락 방지 등 의례와 연계된 음악적 부분까지 관여하고, 그 직무를 책임지는 역할을 감내했다. 이러한 역할 수행 과정에는 전악(典樂)과의 협업 지점이 드러나기도 하는데, 장악원의 조화로운 운영을 위해 장악원 소속 관료와 악인이 함께 노력했던 상황이 투영된 것이다. 의례 절차에 맞게 음악 연주를 챙겨야 했던 협률랑은 궁중의 의례와 음악을 연결해주는 중개자였다.

• 보건의료산업학회지
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• 제8권3호
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• pp.1-11
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• 2014

The present study aimed to survey doctors working in five university hospitals about internal customer satisfaction and organization commitment level in order to identify casual relationships through structure equations. According to the analysis, organization management had the biggest impact on internal customer satisfaction level, and the sooner the factor was named personnel, leadership, job, and compensation, the bigger the impact it had on the level. The research model was generally found to be good in terms of goodness of fit, considering the value of $x^2$ calculated as 103.314, the degrees of freedom of 38, GFI 0.924, AGFT 0.868, NFI 0.888, CFI 0.925, and RMSEA 0.086. In conclusion, the internal customer satisfaction level of doctors was significantly proportionate to organization commitment by means of their general satisfaction level, while also being directly proportionate to organization commitment (p<0.05). Meanwhile, statistical significance could not be found when measuring the effects of the doctors' basic characteristics on the levels of internal customer satisfaction and general satisfaction in hospitals.

• 혜화의학회지
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• 제16권1호
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• pp.147-156
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• 2007

This study was performed to investigate the cause, symptom, treatment of OPLL through Western medicine and Dong-Eui-Bo-Kham(東醫寶鑑) Results & conclusins 1. Ossification of the posterior hgament(OPLL) have radiculopathy, myelopathy or both of them such as neck pain, numbness, myatonia 2. Neck pain of OPLL seems to be simular with pain in the neck(頸項痛), neck stiffness(項强), stiffness and pain of head and neck(頭項彈痛). The causes were usually Dampness and Cold, Wind. The treatments were classified according to pathoigenic factor(病因) and muscle along the regular meridian(經筋) 3. Radiculopathy of OPLL seems to be similar with numbness(痺證). The causes were usually, pathogenic Wind, Cold, Dampness. The treatments were classified according to diagnosis of three kinds of BI syndrome(三痺), five kind of Bi synrome(五痺), five jang Bi(五臟痺), six Bu Bi(六腑痺) 4. Myelopathy of OPLL seems to be simular with myatonia(痿證) The cause of myatoma was Lung scorched by Heat(肺熱葉無). And the treatment was purping the south and reinforcing the north(寫南方 補北方). We considered that more study to find various and effective methods oriental medicine for OPLL should be made.