• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4477-4481
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• 2016

Purpose: To compare the relative merits of imatinib and allogeneic hematopoietic stem cell transplantation (allo-HSCT) for chronic myelogenous leukemia (CML). Materials and Methods: This cohort study was designed to compare the outcomes of imatinib (n=292) versus allo-HSCT (n=141) for CML, the clinical data of these patients being retrospectively analyzed so as to compare the event free survival (EFS) and overall survival (OS) between these two groups with patients in the chronic phase (CP) and advanced phases, including accelerate (AP) and blast phases (BP). Results: (1) Patients treated with imatinib (278 in the CP) demonstrated superior EFS, OS, 5-year EFS and 5-year OS rates of 88.5% versus 70.0% (P<0.05), 93.2% versus 80.0% (P<0.05), 84% versus 75.0% (P<0.05) and 92% versus 79.0% (P<0.05), respectively, to those treated with allo-HSCT (120 patients in the CP). (2) Both treatments resulted in similar survival, with EFS and OS rates of 42.9% versus 47.6% (P>0.05), 42.9% versus 57.1% (P> 0.05), respectively, for imatinib (14 patients in the AP and BP) and allo-HSCT (21 patients in the AP and BP). Conclusions: Imatinib confers significant survival advantage (EFS and OS) for CML patients with CP compared with allo-HSCT treatment. However, the outcomes are equally good with both treatments in AP and BP patients.

• Journal of applied mathematics & informatics
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• v.38 no.1_2
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• pp.145-157
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• 2020

In this article, we define a generating function of the generalized (p, q)-poly-Bernoulli polynomials with variable a by using the polylogarithm function. From the definition, we derive some properties that is concerned with other numbers and polynomials. Furthermore, we construct a special functions and give some symmetric identities involving the generalized (p, q)-poly-Bernoulli polynomials and power sums of the first integers.

• Journal of the Korean Chemical Society
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• v.37 no.1
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• pp.112-118
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• 1993

A water-soluble chromogenic reagent, N,N'-oxalylbis(2-pyridyl-3'-sulphobenzoylhydrazone) has been synthesized. Spectrophotometric and first-and second-derivative spectrophotometric methods for the determination of copper with the reagent have been developed. Determination has been performed by measuring the absorbance and the first-and second-derivative values of the copper complexes in aqueous solutions (pH 1.89) at 379, 395, 363 and 421 nm, respectively. The method allows the determination of 0.12-1.20 ${\mu}g$ /ml of copper and has been applied to the analysis of aluminium alloy samples. The best results have been obtained from the measurements of the second-derivative values at 421 nm.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.1
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• pp.9-15
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• 2011

The first objective of this study was to investigate water pollution status of Meejae Reservoir, Kunsan, irregularly receiving river water for agricultural and recreational purposes. The second objective of the study was to compare nutrient pollution loads of three nutrient sources: sediment leaching, non-point sources and the receiving water. Water analysis results showed that eutrophication was a concern especially in summer and the calculated TSI (secchi depth), TSI (chlorophyll-a), and TSI (TP) were 53.6, 57.7 and 56.7, respectively. Although there was no significant difference in seasonal mean values of sediment T-N, sediment T-P and sediment organic content, mean differences were found for sampling points. However, T-N and T-P sediment release flux showed seasonal mean differences, while showing no mean difference for sampling points. Water T-N data proportionally correlated with sediment T-N and sediment organic content data, while no statistical correlation was found for water T-P data. Comparison of nutrient loads calculated from three sources showed that the highest T-N load was occurred from the receiving (pumped) water while T-P loads of the receiving water and sediment release flux were similar. The first solution would be considered for the receiving water to improve the water quality of Meejae Reservoir. Reduction of nutrient flux from the sediment would be then tried as the second alternative solution.

• Journal of Korean Dental Science
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• v.3 no.1
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• pp.5-10
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• 2010

This study sought to compare the amounts of posterior anchorage loss during the en masse retraction of the upper anterior teeth between orthodontic mini-implant (OMI) and conventional anchorage reinforcement (CAR) such as headgear and/or transpalatal arch. The subjects were 52 adult female patients treated with sliding mechanics (MBT brackets, .022" slot, .019X.025" stainless steel wire, 3M-Unitek, Monrovia, CA, USA). They were allocated into Group 1 (N=24, Class I malocclusion (CI), upper and lower first premolar (UP1LP1) extraction, and CAR), Group 2 (N=15, Cl, UP1LP1 extraction and OMI), and Group 3 (N=13, Class II division 1 malocclusion, upper first and lower second premolar extraction, and OMI). Lateral cephalograms were taken before (T0) and after treatment (T1). A total of 11 anchorage variables were measured. Analysis of variance was used for statistical analysis. There was no significant difference in treatment duration and anchorage variables at T0 among the three groups. Groups 2 and 3 showed significantly larger retraction of the upper incisor edge (U1E-sag, 9.3mm:7.3mm, P<.05) and less posterior anchorage loss (U6M-sag, 0.7~0.9mm:2mm, P<.05; U6A-sag, 0.5mm:2mm, P<.01) than Group 1. The ratio of retraction amount of the upper incisor edge per 1 of anchorage loss in the upper molar made for the significant difference between Groups 1 and 2 (4.6mm:7.0mm, P<.05). Group 3 showed a relatively distal inclination of the upper molar (P<.05) and the intrusion of the upper incisor and first molar (U1E-ver, P<.05; U6F-ver, P<.05) compared to Groups 1 and 2. Although OMI could not shorten the treatment duration, it could provide better maximum posterior anchorage than CAR.

• Vascular Specialist International
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• v.34 no.4
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• pp.94-102
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• 2018

Purpose: Aim of this study is to report real-life experience on the treatment of peripheral artery disease (PAD) with a specific drug-coated balloon (DCB), and to evaluate potential prognostic factors for outcomes. Materials and Methods: This is a retrospective study reporting outcomes in patients with PAD who were treated with the Lutonix DCB during a four-year period. Major outcomes included: all-cause mortality, amputation, clinical improvement, wound healing and target lesion revascularization (TLR). Mean follow-up was $24.2{\pm}2.3$ months. Results: Overall, 149 patients (mean age: $68.6{\pm}8.3$ years; 113 males) were treated, either for intermittent claudication (IC) (n=86) or critical limb ischemia (CLI) (n=63). More than half the target lesions (n=206 in total) were located in the superficial femoral artery and 18.0% were below-the-knee lesions. CLI patients presented more frequently with infrapopliteal (P=0.002) or multilevel disease (P=0.0004). Overall, all-cause mortality during follow-up was 10.7%, amputation-free survival was 81.2% and TLR-free survival was 96.6%. CLI patients showed higher all-cause mortality (P=0.007) and total amputation (P=0.0001) rates as well as lower clinical improvement (P=0.0002), compared to IC patients. Coronary artery disease (CAD), gangrene and infrapopliteal disease were found to be predictors for death whereas CLI and gangrene were found to be predictors for amputation, during follow-up. Conclusion: PAD treatment with Lutonix DCBs seems to be an efficient and safe endovascular strategy yielding promising results. However, CAD, gangrene, CLI and infrapopliteal lesions were found to be independent predictors for adverse outcomes. Larger series are needed to identify additional prognostic factors.

• Bulletin of the Korean Mathematical Society
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• v.58 no.1
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• pp.21-30
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• 2021

In this paper, we prove some rigidity results about embedded minimal hypersurface M ⊂ ℝn+1 with compact ∂M that has one end which is regular at infinity. We first show that if M ⊂ ℝn+1 meets a hyperplane in a constant angle ≥ ��/2, then M is part of an n-dimensional catenoid. We show that if M meets a sphere in a constant angle and ∂M lies in a hemisphere determined by the hyperplane through the center of the sphere and perpendicular to the limit normal vector nM of the end, then M is part of either a hyperplane or an n-dimensional catenoid. We also show that if M is tangent to a C2 convex hypersurface S, which is symmetric about a hyperplane P and nM is parallel to P, then M is also symmetric about P. In special, if S is rotationally symmetric about the xn+1-axis and nM = en+1, then M is also rotationally symmetric about the xn+1-axis.

• Journal of Korean Academy of Nursing
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• v.5 no.2
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• pp.74-91
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• 1975

A purpose of this study was to compare the breast massage and manual expression of the breast before engagement after delivery with the time of engagement, the throbbing pain in breast, the first amount of breast milk and involution of the uterus. The subjects selected for this study were 138 women (experimental group;69, control group :69) who were admitted to the Dept. of Obtest. and Gyneco. of Kyung Hee University Hospital from Jan. 5 to June 5, 1975. The results of study were as follows; 1 The average age of the women 26.9 years old in the experimental group and 27.6 years old in the control group. As to religion, the number of those who had no religion was 58.0 percent and 62.4 percent respectively. Classified according to occupation, there were 87.0 percent in house wives of the booths group. Educational background; 87.0 percent of high school graduates or above, 78.3 percent respectively. The occupation of husband 53.7 percent of company employees stood highest and 42.0 percent respectively. In according to the grade of wards, 55.1 percent and 52.2 percent of four-men room stood highest. 2. Physical condition: Body weight before this Pregnancy(T=0.4962, N.S.), the size of breast(X²df2 = 0.1728, N.S.), the shape of nipple(X²df3 =1.3804, N.S.), hemoglobin's level of the first day after delivery(T=1.2572, N.S.), the above were showed non significant between the experimental group and control group The investigator found any difference between the two groups of the health condition during the pregnancy, 3. The rate of no experience of breast massage during pregnancy was 85 percent and 75.4 percent (X²df1=2.2562, N.S.). 4. As to the meal during hospitalization after delivery: The booth of the groups in ordinary food took usually of meyer soup and milk(X²df8=2.5957, N.S.). 5. The relation between the first step of breast massage, second step of the manual expression of breast before engagement after delivery and time of engagement : average time of engagement in the experimental group (2.1 days±0.8) was shortened than the control group (3.3 days±1.2). (T=-6.9045, P< 0.005). It toot less time in the experimental group of primipara(2.2days±0.7) than in the control group (3.1day±1.2) and it also took less time in the experimental group of multipara (2.0 days±0.9) than in the control group (3.5days±1.4). (Primipara T=-3.9266, 0< 0.005. Multipara T= 5.2356, P<0.005). 6. The relationship between the first step of the massage and second step of manual expression and the throbbing pain at the time of engagement: The experimental group showed less effect than control group (X²df4= 27.3342 P<0.005). The separate study of primipara and multipara showed remarkable difference in the group of primipara)X²df4=20.7285, p<0.005) and little difference in the multipara group (X²df4=8.8351, p< 0. 10). 7. The relationship between the first step of the breast massage, second stop of the manual expression and first amount of breast milk: The average amount of breast milk increased more conspicuously in the experimental group (33.8㎖±23.4) than in the control(29.8㎖±25.3) (T=0.8262, N.S.). No remarkable difference was found in the respective groups that investigated in the groups of primipara and of multipara. (Primipara T=1.1467, N.S., Multipara T=-0.0354, N.S.). 8. The relationship between the first step of breast massage and second step of manual expression of breast and involution of uterus : Average time needed for uttering involution was sooner in the experimental group of primipasa(-3.3 F.B.±1.1), than the control group of primipara (-2.5F. B.±1.2), and it was sooner in the experimental group of muitipara (-3.0 F. B.±l..3), than the control group of multipara(-2.3 F.B±0.9). Primipara T=-2.9272, p< 0.005, Multipara T=2.5557, p< 0.01).

• Journal of applied mathematics & informatics
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• v.27 no.5_6
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• pp.1211-1220
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• 2009

In this paper, we consider the multipoint boundary value problem for the one-dimensional p-Laplacian $({\phi}_p(u'))'$(t)+q(t)f(t,u(t),u'(t))=0, t $\in$ (0, 1), subject to the boundary conditions: $u(0)=\sum\limits_{i=1}^{n-2}{\alpha}_iu({\xi}_i),\;u(1)=\sum\limits_{i=1}^{n-2}{\beta}_iu({\xi}_i)$ where $\phi_p$(s) = $|s|^{n-2}s$, p > 1, $\xi_i$ $\in$ (0, 1) with 0 < $\xi_1$ < $\xi_2$ < $\cdots$ < $\xi{n-2}$ < 1 and ${\alpha}_i,\beta_i{\in}[0,1)$, 0< $\sum{\array}{{n=2}\\{i=1}}{\alpha}_i,\sum{\array}{{n=2}\\{i=1}}{\beta}_i$<1. Using a fixed point theorem due to Bai and Ge, we study the existence of at least three positive solutions to the above boundary value problem. The important point is that the nonlinear term f explicitly involves a first-order derivative.

• Animal cells and systems
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• v.11 no.2
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• pp.247-253
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• 2007

A new species of Nitokra and Ameira parvula (Claus) belonging to the family Ameiridae are recorded from brackish waters in South Korea. Nitokra koreanus n. sp. most resembles N. spinipes and N. pietschmanni, however, it is characteristic in having the character combination of ellipsoidal P5 exopod and very short P1 enp 1. Ameira parvula is reported for the first time from the Northwestern Pacific. Description of the new species and the taxonomic accounts of both species are presented.