• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2002년도 ICCAS
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• pp.39.1-39
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• 2002

We present nanoactuators and nanodetectors for high-precision Micro Electro Mechanical System (MEMS) applications. Major technical difficulties in the high-precision MEMS are arising from the fabrication uncertainty and electrical noise problems. In this paper, we present high-precision actuators and detectors, overcoming the technical limitations placed by the conventional MEMS technology. For the nano-precision actuation, we present a nonlinearly modulated digital actuator (NMDA). NMDA composed of a digital microactuator and a nonlinear micromechanical modulator. The nonlinear micromechanical modulator is intended to purify the actuation errors in the stroke of the digital a...

• Archives of Reconstructive Microsurgery
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• 제14권1호
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• pp.31-36
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• 2005

Purpose: We analyzed the result of the radial forearm island flap for the reconstruction of amputated fingers. Materials and Methods: From March 2001 to February 2004, we assessed two patients who could not be able to receive replantation and six patients who had necrosis of the fingers after replantation. There were six men and two women. The mean age was 42 years. The average duration of follow-up was 26months. Results: All flaps were survived. Two patients needed bone graft. Two patients needed curettage due to osteomyelitis. All patients needed fat reduction procedure. No patients needed amputation of reconstructed digit due to complication. Conclusion: Radial forearm island flap seems useful operation procedure for severely amputated digit or necrotized digit after replantation.

• Archives of Plastic Surgery
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• 제36권1호
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• pp.46-50
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• 2009

Purpose: Finger injury by green onion cutting machine is one of the common hand injuries in the kitchen. It has a unique feature: there are multiple parellel laceration 3 - 5 mm wide. There are two directions of injuries(vertical, oblique). It may involve bone, tendon, nerve, and vessel injuries. We discuss its management and the long - term progress. Methods: We have treated six patients from 2003 to 2007. We carried out low tension approximation with thin suture materials to avoid ischemia and performed the additional operation as nail bed repair, tenorrhaphy, open reduction, vessel anastomosis, and composite graft. We reviewed the record of initial injury and collected the follow - up record. Results: They were all middle aged - women who had worked in the kitchen. Right hand was dominent over left hand. The ratio of the directions was 3 : 3 (vertical : oblique). They were all competely healed although there were three atrophy, four hyperesthesia, and one nail deformity. Conclusion: Finger injury by green onion cutting machine is a unique pattern of laceration with various accompanied injuries. It may look like a severe form of injury, but in most cases have relatively favorable progress. We have to perform careful examination of accompanied injuries and carry out the proper management. First and foremost, the user especially in the middle aged women should be warned to be careful in handling this risky machine.

• 대한골관절종양학회지
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• 제7권1호
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• pp.20-27
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• 2001

목적 : 건초에서 생긴 거대세포종은 수부에서 발생하는 종양 중 두 번째로 흔하나 절제술 후에 재발이 드물지 않으며 국내에서의 연구는 많지 않다. 이에, 저자들은 완관절부를 포함한 수부에 생기는 건초의 거대세포종의 임상적 특성과 수술적 치료후 결과를 분석하여 문헌고찰과 함께 보고하고자 한다. 대상 및 방법 : 1991년부터 1998년까지 수부에서 발생한 종물로 절제생검술을 시행받은 환자 중 조직병리학적으로 건초의 거대세포종으로 진단받은 총 38명, 41예에 대해 성별, 나이, 증상, 증상발현기, 종양이 발생한 부위, 발생한 건, 크기, 다발성 여부, 양측성 여부, 방사선학적 소견 및 골 침범, 재발여부 등에 대해 분석하였으며, 추시기간은 평균 13.1개월(5~40개월)이었다. 결과 : 38명 중 여자에서 29명으로 빈발하였고, 발생연령은 6세에서 66세까지 다양하였으나 50대에서 12례로 가장 호발하였으며 평균연령은 40.1세였다. 지배수지와 비지배수지의 발생경향은 비슷하였고(17례:21례), 모두 일측성이었다. 신전건(17례)보다 굴곡건(24례)에서 더 호발하였으며 증상발현기는 2개월에서 120개월(평균 23.4개월)이었다. 증상으로 대부분 무통성 종물을 호소하였으나, 5례에서 압통, 36례에서 운동장애, 5례에서 압박에 의한 신경증상을 호소하기도 하였다. 재발을 주소로 내원한 경우가 3례였다. 부위별 발생빈도는 수지에서 36례, 수장부에서 3례, 완관절부위 장측에서 2례 순으로 빈발하였으며, 수지별 발생빈도는 인지에서 14례(34%)로 가장 많았고, 엄지가 10례(24%), 중지는 9례, 환지는 5례, 소지는 3례의 빈도순을 보였다. 수지상 발생부위는 원위지골간 관절부 및 중위지골부에서 20례(48.8%), 근위지골 및 근위지골간 관절부가 9례, 중수지절관절부가 7례 순으로 호발하였다. 방사선학적 소견상 연부조직에 방사선 비투과적인 균일한 연부조직 음영을 보이고 있었고 3명에서 피질골 미란을 보였다. 37명에서 종양은 단발성 병변이었으나 이 중 4명에서 다엽상으로 넓게 분포하였고, 1명에서 다발성 병변을 보였다. 변연부 절제술후 재발된 경우가 2명으로 재발율은 5.1%였다. 결론 : 수부에서 발생한 건초의 거대 세포종은 호발조건으로 50대, 여성, 인지, 굴곡건, 수지 원위부를 추정해 볼 수 있었으며, 불완전한 변연부 절제술을 시행하거나, 수술 후 재발한 경우, 다발성, 다엽상 소견을 보인 경우 재발이 잘 되므로 이 경우 광범위 절제술이 필요할 것으로 사료된다.

• 동의생리병리학회지
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• 제23권5호
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• pp.1183-1187
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• 2009

We presented an ataxia patient who was difficult to diagnose and treated her by oriental medical treatment. We applied various methods of oriental medicine including herb medicine, acupunture, moxibustion and so on. After that, we checked the extent of dysarthria, pruritus, finger to nose and rapid alternative movement and measured the progress of general condition with Modified Barthel Index(MBI). After the oriental medical treatment was applied to her, ataxia, dysarthria, pruritus, finger to nose and rapid alternative movement were improved. The score of MBI was improved from 45 to 71, too. Even though there is no exact pattern identification about ataxia in oriental medicine, the oriental medicine can have an effect on the ataxia patient. In addition, more clinical study and observation should be needed.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권1호
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• pp.378-390
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• 2015

Image projectors can turn any surface into a display. Integrating a surface projection with a user interface transforms it into an interactive display with many possible applications. Hand gesture interfaces are often used with projector-camera systems. Hand detection through color image processing is affected by the surrounding environment. The lack of illumination and color details greatly influences the detection process and drops the recognition success rate. In addition, there can be interference from the projection system itself due to image projection. In order to overcome these problems, a gesture interface based on depth images is proposed for projected surfaces. In this paper, a depth camera is used for hand recognition and for effectively extracting the area of the hand from the scene. A hand detection and finger tracking method based on depth images is proposed. Based on the proposed method, a touch interface for the projected surface is implemented and evaluated.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1343-1348
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• 2015

Human UHRF1 (ubiquitin-like PHD and RING finger domain-containing 1) has been reported to be over-expressed in many cancers, but its role in ovarian cancer remains elusive. Here, we determined whether knockdown of UHRF1 by lentivirus-mediated shRNA could inhibit ovarian cancer cell growth. Lentivirus-mediated short hairpin RNAs (lv-shRNAs-UHRF1) were designed to trigger the gene silencing RNA interference (RNAi) pathway. The efficiency of lentivirus-mediated shRNA infection into HO-8910 and HO-8910 PM cells was determined using fluorescence microscopy to observe lentivirus-mediated GFP expression and was confirmed to be over 80 percent. UHRF1 expression in infected HO-8910 and HO-8910 PM was evaluated by real-time PCR and Western blot analysis. The Cell Counting Kit-8 (CCK-8) assay was used to measure cell viability; flow cytometry and Hoechst 33342 assay was applied to measure cell cycle arrest and apoptosis. Cell invasion was assessed using transwell chambers. Our results demonstrated that the loss of UHRF1 promoted HO-8910 and HO-8910 PM cell apoptosis, while inhibiting cell proliferation. In addition, UHRF1 knockdown significantly inhibited the invasion of human ovarian cancer cells. In the present study, we also showed that depleting HO-8910 cells of UHRF1 caused activation of the DNA damage response pathway, with the cell cycle arrested in G2/M-phase. The DNA damage response in cells depleted of UHRF1 was illustrated by phosphorylation of CHK (checkpoint kinase) 2 on Thr68, phosphorylation of CDC25 (cell division control 25) on Ser 216 and phosphorylation of CDK1 (cyclin-dependent kinase 1) on Tyr 15.

• Annals of Clinical Neurophysiology
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• 제2권1호
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• pp.21-26
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• 2000

저자들은 정상 대조군과 CTS 환자군을 대상으로 막대전극을 이용하여 M P P D N의 감각신경전도검사를 실시하여 다음과 같은 결과를 얻었다. 1. MPPDN의 감각신경전도속도의 정상범위는 $38.7{\pm}4.2$(D1), $32.0{\pm}4.6$(D2), $34.2{\pm}4.4$(D3) m/sec로서 서로 유의한 차이가 있었다. 2. MPPDN의 감각신경전도속도의 정상범위는 좌우에서 서로 유의한 차이가 없었다. 3. CTS 환자에서 측정한 MPPDN의 감각신경전도속도는 각각 $35.3{\pm}8.9$(D1), $20.2{\pm}5.2$(D2), $20.2{\pm}5.1$(D3) m/sec로서 대조군에서 얻은 정상범위와 유의한 차이가 있었다.

• Journal of Yeungnam Medical Science
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• 제5권1호
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• pp.23-32
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• 1988

저자는 1986년 3월부터 1988년 2월까지 2년동안 영남대학교 의과대학 부속병원 성형외과에 내원한 수지절단환자 75명, 102수지에 재해 수지재접합술을 시행하여 다음과 같은 결과를 얻었다. 1. 연령별분포에서는 20대에서 가장 많이 발생하였고, 남녀의 비율은 약 5:1로써 남자에서 현저히 많이 발생하였다. 2. 좌 우수의 발생빈도는 비슷한 분포를 보였으나 지배수와 비지배수의 비율에서는 지배수가 2배 이상 많이 발생하였다. 3. 수지별분포에서는 시지에서 가장 많이 발생하였고 그 다음으로는 중지에서 많이 발생하였다. 4. 손상의 원인으로는 압력기종류가 가장 흔하였고, 손상형태로는 좌멸창이 가장 많았다. 5. 마취방법에서는 국소마취와 전신마취가 비슷한 분포로 시행되었다. 6. zone II절단인 경우에는 77.8%의 성공률을, zone III의 절단인 경우에는 80%의 성공율을 나타내었다. 7. zone III절단인 경우보다 zone II절단인 경우에서 술후 수지기능이 더 좋았다. 8. 수지재접합술은 손상상태의 정도나 원인, 허혈시간에 관계없이 시행하였으며, 환자의 재접합술에 대한 요구도 무시할 수 없는 사항이었다.

• 대한한방내과학회지
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• 제28권4호
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• pp.733-740
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• 2007

Objective : This study investigated the relationship between warning signs and Sasang constitution (SC) in acute stroke patients. Methods : From October in 2005 to March in 2007, 629 acute stroke patients were studied. Patients were hospitalized within 14 days after the onset ofstroke at one of 3 oriental medical hospitals in Seoul and Kyong-gi province. We assessed the type of SC of acute stroke patients by Questionnaire for Sasang Constitution Classification II (QSCC II). We investigated warning signs (motor weakness, blindness, dysarthria, sensory disturbance, finger dullness, facial & eyelid spasm, neck stiffness), general characteristics, etc. Results : This study showed a higher proportion of Tae-eum & So-eum experience upper extremity sensory disturbance but So-yangexperience lower extremity sensory disturbance. Smoker So-eumexperience 1st & 2nd finger dullness more than non-smoker So-eum. So-eum women experience motor weakness more than So-eum men. Conclusion : Besides these results, we could observe almost no relationship between warning signs and Sasang constitution (SC) in acute stroke patients. More data from prospective cohort studies will help people better understand the relationship between warning signs and Sasang constitution (SC) in acute stroke patients.