• Korean Journal of Community Nutrition
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• v.24 no.5
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• pp.395-407
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• 2019

Objectives: This study examined the association of the sleep quality and patterns with the dietary behavior, including snack and beverage consumption, taste preferences, as well as lifestyle of university students. Methods: The subjects were 406 university students in Cheongju, Korea, and the data were collected using a self-administered questionnaire. They were divided into two groups according to the Pittsburgh Sleep Quality Index (PSQI): good-quality sleepers (PSQI score ≤ 5) and poor-quality sleepers (PSQI score > 5). The data were analyzed using a χ²-test, independent t-test, and analysis of covariance using the SPSS 25.0 program. Results: Fifty-two percent of university students were categorized as poor-quality sleepers by the PSQI. Students classified as poor-quality sleepers had delayed bedtimes, and a shorter duration in bed and total sleep hours than the good-quality sleepers did. Poor-quality sleepers were more prevalent among those who were female, having irregular mealtimes, or frequent late night meals. They also consumed fast food frequently, such as fried chicken and hamburgers, and noodles when adjusted for gender. In addition, drinks with caffeine over milk were dominant among poor-quality sleepers. Furthermore, the preferences for spicy and salty tastes and longer smartphone usage were more prevalent in those with poor-sleep quality. Conclusions: These results showed that more than 50% of university students reported disturbed sleep and poor quality sleep was associated with less desirable snack consumption and taste preference, more smartphone usage, and others. Therefore, nutrition education program along with lifestyle changes promoting sufficient sleep are encouraged to provide for university students, particularly those who have poor sleep quality.

• Applied Biological Chemistry
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• v.43 no.3
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• pp.174-178
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• 2000

To search CDK4/Cyclin D1 enzyme inhibition materials, methanol extracts of native eighty seven plant species in thirty seven families were screened in vitro for their inhibiting activities against CDK4/Cyclin D1 enzyme which are control to the normal cell division cycle in human body. Extracts of Paeonia suffruticosa, Saurus chinensis, Sanguisorba officinalis and Celastrus orbiculatus among them significantly inhibited above fifty percent $(in\;5\;{\mu}g/ml)$ against CDK4/ Cyclin D1 enzyme. Especially, the extracts of P. suffruticosa and S. officinalis showed moderately strong inhibition. Also, cryptotanshinone was identified as active compound from a extracts of Salvia mitiorrhiza by spectroscopic analyses including 2D NMR experiments.

• Research in Plant Disease
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• v.18 no.1
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• pp.40-44
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• 2012

Xanthomonas arboricola pv. pruni is the causal agent of bacterial black spot disease on some stone fruits, e.g. peach, plum and apricot. To evaluate pathogenicity of Xanthomonas arboricola pv. pruni strain from plum, inoculum of the isolated strain was spray inoculated to fruits and leaves of apricot, Japanese apricot and plum. Apricot and Japanese apricot showed severe black spot symptoms on fruits and shot hole symptoms on leaves. In case of apricot, about fifty percent of fruits did not grow and dropped by hypersensitive reaction to spray infection. Plum, cv. Formosa was very susceptible, showing severe black injury lesions on fruits and cankers on leaves and new twigs. On the other hand, plum cv. Daesukjosaeng, was highly resistant. Fruits of several plum cultivars such as Formosa and Chuhee were severely infected at natural infected orchards by X. arboricola pv. pruni. Where as those of Daesukjosaeng, Taeyang, Soldam and Hongrogen were moderately infected.

• Journal of Korean Society of Transportation
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• v.24 no.5 s.91
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• pp.19-33
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• 2006

This paper presents the results of an experimental study on the application of NTCIP protocol to Korean traffic signal control system. For this study the communication Protocol of the existing traffic signal control system was adjusted to meet NTCIP standard. Management information base for Korea real-time traffic signal control system, message library of OER, traffic control center management software supporting SNMP/SFMP Protocol, and agent softwares for local controllers were developed during the experimental study. The applicability test of the adjusted system by NTCIP standard was performed. Fifty eight Percent of communication packets were lost at 2.400bps communication speed, which made the operation impossible. The experimentations with communication speeds 4,800bps and 9,600bps did not cause problems. In conclusion, to apply the NTCIP standard to domestic real-time traffic control system, communication environments need to be upgraded to 4,800bps or higher.

• International Journal of Highway Engineering
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• v.11 no.1
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• pp.145-151
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• 2009

Current highway design standards is based on the safety under the free flow condition. The length of deceleration lane is also determined in terms of the deceleration distance which is necessary for the driers to adjust the vehicle speed from the speed limit on the main road to that on the exit ramp of the interchange. However, the queues are frequently developed on the deceleration, and the following vehicles to exit must decelerate on the main road. It may cause delay on the main road and traffic accidents. This study is to suggest a methodology to minimize such problems with the shock-wave theory. The queue length of exiting vehicles can be estimated by the design speeds, traffic volumes of main road and the exiting ramp, and the countermeasures to the operational problems. According to the results, the queue length can be shortened to 80% by upgrading the design speed of exit ramp as the amount of 10km/h. Fifty percent of queue length can be shortened by adding an additional lane on the ramp to two lanes.

• Korean Journal of Plant Tissue Culture
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• v.25 no.3
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• pp.183-187
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• 1998

Chlorophyll mutants were produced by treating the rhizome of Cymbidium kanran with mutagen, EMS(ethyl methan sulfonate). The germination ratio of Cymbidium kanran seeds was 5.5 times higher when the seeds were treated with ultrasonic treatment for 20 minutes than untreated control. Fifty to sixty percent of the rhizomes became dark brown when they were cultured in a liquid growth medium containing 0.2% EMS for three weeks. When the dark-brown rhizomes were cultured in a solified MS medium, new rhizomes were developed from a part of the old ones. Chlorophyll mutant rhizomes were obtained from a meristem tissue by a subculturing the cuts of these new rhizomes for a year. Of the chlorophyll mutants, a zigzag-striped type of rhizome was dominant and light-yellow and albino ones were also produced. While the zigzag-striped type rhizomes were differentiated into green and striped plant, the light yellow and the white rhizomes produced yellow-striped and albino plants repectively.These results indicate that the EMS treatment on the rhizome is an effective means to induce a chlorophyll mutant. We believe that this method may be useful to produce variegated plants chlorophyll mutants from other orchids.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.3
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• pp.13-20
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• 2019

Objectives : The aim of this study is to investigate the use experience of other medical institution of outpatients of Korean medical institution. Methods : Cross-sectional study using the 2017 Korean Medicine Utilization and Herbal Medicine Consumption Survey was conducted. Demographic variables and frequent diseases were analyzed according to the experience of using other medical institutions. The proportions of experience of using other medical institutions of patients with frequent diseases of Korean medical outpatient were analyzed. Results : Fifty-three percent of outpatient had experiencing using other medical institutions for the same symptoms. The frequent diseases of the two groups were similar. The proportion of single use of Korean medicine for injury of lumbar and pelvic, rhinitis, and menstrual disorders were relatively high. Conclusions : There was no notable difference in the frequent diseases according to use experience of other medical institution. Further studies on this topic are needed.

• Biomolecules & Therapeutics
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• v.10 no.4
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• pp.274-280
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• 2002

The fluoroquinolones have been reported to cause, although at low frequency, severe phototoxicity which is due to singlet oxygen produced by ultraviolet-A (UVA; 320-400 nm) exposure. The objective of this study was to evaluate the phototoxicity based on plasma and tissue concentrations of commonly prescribed fluoroquinolones; lomefloxacin (LFLX), enoxacin (ENX), ofloxacin (OFLX), and ciprofloxacin (CPFX). The phototoxic potentials were investigated by measuring increments in ear thickness, 24 hrs after these fluoroquinolones were orally administered to Balb/c mice, which they were exposed to UVA 17.5 J/$\textrm{cm}^2$ for 2 hrs following drug administration. The fifty percent ear thickness increment-inducing doses ($ETID_{50}$), determined by single ascending dosing of each fluoroquinolone to mice, were calculated to be 50(LMFX), 250(ENX), 770(OFLX), 1100(CPFX) mg/kg. Post the administration of ETID$_{50}$, drug concentrations in plasma and ear tissue were measured at specified times and phototoxicities were quantified. Both peak plasma ($\mu\textrm{g}$/ml) and ear tissue ($\mu\textrm{g}$/g) concentrations were summarized as follows; 7.3/1.4 for LMFX, 15.0/1.6 for ENX, 90.1/18.4 for OFLX and 87.2/3.7 for CPFX. The degree of photo toxicity was more relevant to plasma concentrations than tissue concentrations. In order to assess the effect of irradiation time after drug administration on phototoxicity, the 2 hr UVA irradiation was given at 0, 1, 2, 3, and 5 hr after administering $ETID_{50}$, respectively and photo toxicities were evaluated. The shorter inteval between dosing and UVA exposure was, the higher risk of phototoxicity was produced.d.

• Korean Journal of Hospice Care
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• v.5 no.2
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• pp.15-21
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• 2005

Purpose: This study was designed to evaluate the perception of cancer in aspirants for hospice volunteer. Methods: Aspirants for hospice volunteer were surveyed by questionnaire before education of hospice program in September 2005 at Pyongan Hospice Center of Sam Anyang Hospital. The questionnaire was composed of total 28 items. Ten items were general characteristics and the remaining 18 items knowledge, attitude and practice of cancer and cancer pain. The data were analyzed by SPSS WIN 11.0 program using frequency, mean, percentage. Results: Eighty nine questionnaires were returned. There were 6 males and 83 females, and median age of aspirants was 46 years. Forty five aspirants(51%) had a cancer patient in th family or relatives and the others 44(49%) not. Forty eight(54%) had favorable attitude about modern clinical medicine for cancer treatment and the others 39(44%) unfavorable. Fifty eight(65%) had favorable attitude about complementary and alternative medicine for cancer treatment and the others 20(23%). In response to the question about 'How illness is a cancer', 25 aspirants(25%) responded to chronic disease, 42(47%) suffering incurable disease, the others 17(19%) death sentence, respectively. A number of aspirants had wrong knowledge and understanding of cancer, cancer pain and opioid analgesics. Seventy one percent aspirants feared cancer pain. Conclusion: The credibility to modern clinical medicine for cancer treatment was relatively low in aspirants for hospice volunteer compared with complementary and alternative medicine. They recognized a cancer as suffering incurable disease and death sentence than chronic disease. A number of aspirants had wrong knowledge of cancer, cancer pain and opioid analgesics. Therefore, further studies and trial will be warranted to evaluated the causes of these results and improve the credibility of modern clinical medicine for cancer treatment in general population.

• Perinatology
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• v.28 no.2
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• pp.47-58
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• 2017

Objective: We evaluated the Korean mothers' level of awareness of human milk bank (HMB) in order to find out the issues in establishing HMB in Korea. These mothers had infants younger than 18 months old to find out the issues that would help establishment of HMB in Korea. Methods: The survey questionnaire was developed by a team composed by nurses, neonatologists, obstetricians, nutritionists, health care specialists and faculty members. The internet survey was performed by sending emails to mothers who are registered to M family members and have children younger than 18 months. In total, 864 questionnaire were gathered from 114,469 answers and the results were analyzed. Results: Fifty two point eight percent of the respondents had awareness of HMB. 79.4% of subjects agreed with the necessity of HMB. On the basis of multivariate logistic regression analysis, we found that the numbers of children, awareness of HMB, the concern on the HMB in Korea, and the expected problems in establishing HMB in Korea were significant factors when evaluating the necessity of HMB in Korea. The common factors associated with positive thinking of potential users, donors and recipients were the awareness of HMB, and the experience of feeding own breast milk to other's babies. Conclusion: More than half of Korean women were found to agree with the necessity of HMB in Korea, even though they had concern on infection controls and management of HMB and the purpose and function of HMB was not widely educated. The establishment of HMB in Korea would be effective with public education and considering their demands.