• Bulletin of the Korean Chemical Society
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• v.32 no.5
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• pp.1604-1612
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• 2011

We developed three-dimensional quantitative structure activity relationship (3D-QASR) models for 17 adamantyl derivatives as P-glycoprotein (P-gp) inhibitors. Eighteen different partial charge calculation methods were tested to check the feasibility of the 3D-QSAR models. Best predictive comparative molecular field analysis (CoMFA) model was obtained with the Austin Model 1-Bond Charge Correction (AM1-BCC) atomic charge. The 3D-QSAR models were derived with CoMFA and comparative molecular similarity indices analysis (CoMSIA). The final CoMFA model ($q^2$ = 0.764, $r^2$ = 0.988) was calculated with an AM1-BCC charge and electrostatic parameter, whereas the CoMSIA model ($q^2$ = 0.655, $r^2$ = 0.964) was derived with an AM1-BCC charge and combined steric, electrostatic, hydrophobic and HB-acceptor parameters. Leave-five-out (LFO) cross-validation was also performed, which yielded good correlation coefficient for both CoMFA (0.801) and CoMSIA (0.656) models. Robustness of the developed models was checked further with 1000 run bootstrapping analyses, which gave an acceptable correlation coefficient for CoMFA (BS-$r^2$ = 0.997, BS-SD = 0.003) and CoMSIA (BS-$r^2$ = 0.996, BS-SD = 0.018).

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.5
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• pp.235-241
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• 2015

Nowadays, research and industry on the internet of things is rapidly developing. Bug fixed field of the Software development related internet of things is a very important things. In this study, we analyze the properties that can affect what the bug fix-time by analyzing the time required to fix a bug associated with the Internet of Things. Using the k-NN classification method based on the attribute information to be classified as bug reports. Extracts a bug report based on the results of a similar property. Bug fixed by calculating the time of a similar bug report predicts the fix-time for new bugs. Depending on the prediction of the properties that affect the bug correction time, the properties of os, component, reporter, and assignee showed the best prediction accuracy.

• Steel and Composite Structures
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• v.26 no.2
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• pp.125-137
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• 2018

In this work, the bending and free vibration analysis of multilayered plates and shells is presented by utilizing a new higher order shear deformation theory (HSDT). The proposed involves only four unknowns, which is even less than the first shear deformation theory (FSDT) and without requiring the shear correction coefficient. Unlike the conventional HSDTs, the present one presents a novel displacement field which incorporates undetermined integral variables. The equations of motion are derived by using the Hamilton's principle. These equations are then solved via Navier-type, closed form solutions. Bending and vibration results are found for cylindrical and spherical shells and plates for simply supported boundary conditions. Bending and vibration problems are treated as individual cases. Panels are subjected to sinusoidal, distributed and point loads. Results are presented for thick to thin as well as shallow and deep shells. The computed results are compared with the exact 3D elasticity theory and with several other conventional HSDTs. The proposed HSDT is found to be precise compared to other several existing ones for investigating the static and dynamic response of isotropic and multilayered composite shell and plate structures.

• Wind and Structures
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• v.27 no.4
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• pp.269-282
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• 2018

In this paper, a new displacement field based on quasi-3D hybrid-type higher order shear deformation theory is developed to analyze the static and dynamic response of exponential (E), power-law (P) and sigmoïd (S) functionally graded beams. Novelty of this theory is that involve just three unknowns with including stretching effect, as opposed to four or even greater numbers in other shear and normal deformation theories. It also accounts for a parabolic distribution of the transverse shear stresses across the thickness, and satisfies the zero traction boundary conditions at beams surfaces without introducing a shear correction factor. The beam governing equations and boundary conditions are determined by employing the Hamilton's principle. Navier-type analytical solutions of bending and free vibration analysis are provided for simply supported beams subjected to uniform distribution loads. The effect of the sigmoid, exponent and power-law volume fraction, the thickness stretching and the material length scale parameter on the deflection, stresses and natural frequencies are discussed in tabular and graphical forms. The obtained results are compared with previously published results to verify the performance of this theory. It was clearly shown that this theory is not only accurate and efficient but almost comparable to other higher order shear deformation theories that contain more number of unknowns.

• Structural Engineering and Mechanics
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• v.67 no.5
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• pp.527-544
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• 2018

In this paper, the effect of homogenization models on stress analysis is presented for functionally graded plates (FGMs). The derivation of the effective elastic proprieties of the FGMs, which are a combination of both ceramic and metallic phase materials, is of most of importance. The majority of studies in the last decade, the Voigt homogenization model explored to derive the effective elastic proprieties of FGMs at macroscopic-scale in order to study their mechanical responses. In this work, various homogenization models were used to derive the effective elastic proprieties of FGMs. The effect of these models on the stress analysis have also been presented and discussed through a comparative study. So as to show this effect, a refined plate theory is formulated and evaluated, the number of unknowns and governing equations were reduced by dividing the transverse displacement into both bending and shear parts. Based on sinusoidal variation of displacement field trough the thickness, the shear stresses on top and bottom surfaces of plate were vanished and the shear correction factor was avoided. Governing equations of equilibrium were derived from the principle of virtual displacements. Analytical solutions of the stress analysis were obtained for simply supported FGM plates. The obtained results of the displacements and stresses were compared with those predicted by other plate theories available in the literature. This study demonstrates the sensitivity of the obtained results to different homogenization models and that the results generated may vary considerably from one theory to another. Finally, this study offers benchmark results for the multi-scale analysis of functionally graded plates.

• Journal of the Korean Geosynthetics Society
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• v.14 no.4
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• pp.97-104
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• 2015

When carrying out design for soft ground improvement before reclamation of dredged soil, it is very important to appropriately evaluate design parameters such as compression index and undrained strength in order to estimate optimum construction cost. In this study, consolidation and strength parameters were estimated by the samples obtained from the similar reclaimed land. Water content and compression index of dredged soil reclaimed by hydraulic fill method were quite decreased in comparison with those of in-situ conditions at Incheon site. Relationships between compression index(Cc) and water content (wn), and between undrained strength (su) and water content (wn) for dredged soil were obtained by field vane test and oedometer test, respectively. Applicability of Schmertmann correction method (compression index) for low plasticity silty soil was discussed according to comparison with designed and measured settlements.

• The Journal of Engineering Geology
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• v.5 no.3
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• pp.277-288
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• 1995

Fracture detection has always been very attractive to the log, because it is important in many of our prospecting activities, e.g. in understanding the underground rock formation and also the fluid flow as a high permeability path. This paper demonstrates the use of high resolution borehole acoustic scanner for the detection of fractures. The tool, known as Televiewer, is the first acoustic borehole imaging system to use a focussed beam. The acoustic beams generated by a single transducer are sent toward the borehole wall, scanning the wall in a tight helix as the tool moves along the borehole. The amplitudes and travel times of the reflected signals are then measured, which produces the corresponding images. The highly resolved amplitude image allows to recognize various size of fractures and in addition to derive the rock strength from the image. Meanwhile, the travel time image itself can be directly converted to a precise caliper image, providing detailed information of deviations of the borehole shape. It also allows correction of and explanations for amplitude variations. Field measurements were carried Out at the Cheongyang study sites in Korea to illustrate the efficiency of the televiewer log.

• Journal of Korean Society of Disaster and Security
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• v.9 no.1
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• pp.39-45
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• 2016

The disasters in Korea, such as the Sewol Ferry Ship sinking disaster has had problems related to the medical response system, with the problems of emergency medical support team in the site, the cooperation between medical staff and fire department officer at disaster site, field medical support and hospital acceptance of the wounded in trouble, the lack of specific systematic medical response manual. Therefore, from May 2014, when the disaster emergency information center in Central Emergency Medical Center starts, collection, modification and education of scattered preexisting disaster emergency medical manual had appeared as important issues. So, it was necessary to develop the early medical response system to disaster. The correction planning of disaster emergency medical response system by Central Emergency Medical Center included quick response system with the fast medical team operation, but the practical application was not enough. So the researcher and his team developed the first Korean disaster emergency medical response manual and the process of development was documented and arranged with the application by education and training.

• Journal of Broadcast Engineering
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• v.21 no.1
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• pp.43-50
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• 2016

In this paper, we present a distortion correction for wearable Augmented Reality (AR) on mobile phones. Head Mounted Display (HMD) using mobile phones, such as Samsung Gear VR or Google's cardboard, introduces lens distortion of the rendered image to user. Especially, in case of AR the distortion is more complicated due to the duplicated optical systems from mobile phone's camera and HMD's lens. Furthermore, such distortions generate mismatches of the visual cognition or perception of the user. In a natural way, we can assume that transparent wearable displays are the ultimate visual system which generates the least misperception. Therefore, the image from the mobile phone must be corrected to cancel this distortion to make transparent-like AR display with mobile phone based HMD. We developed a transparent-like display in the mobile wearable AR environment focusing on two issues: pincushion distortion and field-of view. We implemented our technique and evaluated their performance.

• Journal of Broadcast Engineering
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• v.21 no.3
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• pp.357-368
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• 2016

In DAB+, HE-AAC v2 codec is applied for the fixed rate transmission of audio stream. In case that xHE-AAC codec including USAC, a more efficiency is expected when the variable frame is used in a given same bandwidth compared to the fixed frame transmission. For this to be realized, audio streams need to be multiplexed in a sub-channel before transmission, then a method is required to identify the border of each audio frames. In this paper, the toggled sync byte and additional identification field being sequentially placed between AU borders are proposed in order to deal with the AU border identification. In addition, the Reed-Solomon based error correction code which is compliant to DAB+ is proposed.