• The Korean Journal of Physiology
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• v.20 no.1
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• pp.89-102
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• 1986

It has long been suggested that the change of renin-angiotensin system is responsible for the increased arterial blood pressure in the experimental hypertension. But the exact nature of the cause and maintenance of early and late Phase of renal hypertension is still controversial. Increased renin-angiotensin system has been suggested. To clarify the altered renin-angiotensin system in the early phase of two kidney one clip Goldblatt hypertension(2K1C GH), experiments were carried out in the rats of 3,7, and 14 days of 2K1C GH rats, sham-operated, and control rats. Responses of the plasma renin activity to the intravenous infusion of L-isoproterenol were dose-dependent. Responses of the plasma renin activity to the intravenous L-isoproterenol in 2K1C GH rats were not different from sham-operated control rats. Hypotensive responses of the 2K1C GH rats were not different from sham-operated rats. Suppression by intravenous infusion of angiotensin II of plasma renin activity showed a dose-dependent manner. Suppression by angiotensin ll of plasma renin activity was attenuated or abolished in the early phase of 2K1C GH rats. Intravenous infusion of arginine vasopressin(AVP) showed a dose-dependent suppression of plasma renin activity, Attenuated responses by AVP of plasma renin activity were noticed in the early phase of 2K1C GH rats. These results suggest that the altered renin-angiotensin system in the early phase of the two kidney one clip Goldblatt hypertension may be caused by failure of the short loop negative feedback control mechanism.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.196-201
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• 2004

In biometric and biomedical applications, a special transporting mechanism must be designed for the ${\mu}$TAS (micro total analysis system) to move samples and reagents through the microchannels that connect the unit procedure components in the system. An important issue for this miniaturization and integration is microfluid management technique, i.e., microfluid transportation, metering, and mixing. In view of this, this study presents an optimal fuzzy sliding-mode control (OFSMC) design based on the 8051 microprocessor and implementation of a complete microfluidic manipulated system implementation of biochip system with a pneumatic pumping actuator, a feedback-signal photodiodes and flowmeter. The new microfluid management technique successfully improved the efficiency of molecular biology reaction by increasing the velocity of the target nucleic acid molecules, which increases the effective collision into the probe molecules as the target molecules flow back and forth. Therefore, this hybridization chip was able to increase hybridization signal 6-fold and reduce non-specific target-probe binding and background noises within 30 minutes, as compared to conventional hybridization methods, which may take from 4 hours to overnight. In addition, the new technique was also used in DNA extraction. When serum existed in the fluid, the extraction efficiency of immobilized beads with solution flowing back and forth was 88-fold higher than that of free-beads.

• Transactions of the Korean Society of Automotive Engineers
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• v.10 no.1
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• pp.209-215
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• 2002

A study of the guideway vehicle was made for a comparison of ride stabilities between its two primary steering types; one is the front wheel steering and the other the front-rear wheel. A numerical model as a closed loop system was built for an investigation of various factors to have an influence on the vehicular critical speed which is closely associated with ridabilities. It was shown that dynamics stabilities of the front steering type was much better over a large value of steering gain and the longer distance between front axle and guide link for both types provided better stabilities as well. A large steering gain ratio of the front to the rear significantly plays an important role in an improvement of stability in the front-rear steering. To observe a qualitative trend on stability behaviors, the root locus was obtained by considering a time lag which may be frequently caused by the complicated steering mechanism. In performing so, the appropriate selection of steering gain had a greater effect on the front-rear steering vehicle far more ride comfort. In addition, the dynamics model proposed here can be utilized for a more accurate evaluation on the vehicle design in lateral or yawing absorber and moreover expanded for the analysis of independent four-wheel steering vehicle.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.3
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• pp.66-78
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• 1995

In this paper, we address vehicle modeling and dynamic analysis of four wheel steering systems (4WS). 4WS is one of the devices used for the improvement of vehicle maneuverability and stability. All research done here is based on a production vehicle from a manufacturer. To study actual system response, a three dimensional, full vehicle model was created. In past research of this type, simple, two dimensional, bicycle vehicle models were typically used. First, we modelled and performed a dynamic analysis on a conventional two wheel steering(2WS) vehicle. The modeling and analysis for this model and subsequent 4WS vehicles were performed using ADAMS(Automatic Dynamic Analysis of Mechanical Systems) software. After the original vehicle model was verified with actual experiment results, the rear steering mechanism for the 4WS vehicle was modelled and the rear suspension was changed to McPherson-type forming a four wheel independent suspension system. Three different 4WS systems were analyzed. The first system applied a mechanical linkage between the front and rear steering mechanisms. The second and third systems used, simple control logic based on the speed and yaw rate of the vehicle. 4WS vehicle proved dynamic results through double lane change test.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.244-247
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• 2002

The performance of the precision micro-positioning 4-dof stage is presented. The compact design utilizes the monolithic mechanism to achieve the translation in the Z axis and rotation in the $\theta$ z, $\theta$ x and $\theta$ y axes with high stiffness and high damping. Hysteresis, nonlinearity, and drift of the piezoelectric effects are improved by incorporating the sensors in a feedback control. Experiments demonstrate that the micro-positioning stage is capable of 2nm resolution over the travel range of 25$\mu\textrm$ m in the Z axis, 0.0l7 $\mu\textrm$ rad resolution over the 170$\mu\textrm$ rad in the $\theta$ z and 0.011 $\mu\textrm$ rad resolution over the $\mu\textrm$ rad in the $\theta$ x and $\theta$ y axes. The cross-axis interferences among the axes are at a noise range. This stage is available for positioning error compensation of the XY stage with large stroke.

• Journal of Korean Society of Water and Wastewater
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• v.34 no.2
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• pp.105-114
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• 2020

In this study, based on the System Dynamics (SD) methodology, the interrelationship between the factors inherent in the operation of the New Technology Certification System (NTCS) in Korea was identified by a causal map containing a feedback loop mechanism in connection with 'new technology development investment', 'commercialization of new technology', and 'sales by new technology'. This conceptualized causal map was applied to the simulation of the operations of the New Excellent Technology and Environmental Technology Verification System (NET&ETV) run by the Ministry of Environment among various NTCSs in Korea. A SD computer simulation model was developed to analyze and predict the operational performance of the NET&ETV in terms of key performance indices such as 'sales by new technology'. Using this model, we predicted the future operational status the NET&ETV and found a policy leverage that greatly influences the operation of the NET&ETV. Also the sensitivity of the key indicators to changes in the external variables in the model was analyzed to find policy leverage.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2001.01a
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• pp.278-282
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• 2001

The discovery of tacit knowledge from domain experts is one of the most exciting challenges in today\`s knowledge management. The nature of decision knowledge in determining the quality a firm\`s short-term liquidity is full of abstraction, ambiguity, and incompleteness, and presents a typical tacit knowledge extraction problem. In dealing with knowledge discovery of this nature, we propose a scheme that integrates both knowledge elicitation and knowledge discovery in the knowledge engineering processes. The knowledge elicitation component applies the Verbal Protocol Analysis to establish industrial cases as the basic knowledge data set. The knowledge discovery component then applies fuzzy clustering to the data set to build a fuzzy knowledge based system, which consists of a set of fuzzy rules representing the decision knowledge, and membership functions of each decision factor for verifying linguistic expression in the rules. The experimental results confirm that the proposed scheme can effectively discover the expert\`s tacit knowledge, and works as a feedback mechanism for human experts to fine-tune the conversion processes of converting tacit knowledge into implicit knowledge.

• Journal of Communications and Networks
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• v.12 no.5
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• pp.499-509
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• 2010

A plethora of transmission control protocol (TCP) congestion control algorithms have been devoted to achieving the ultimate goal of high link utilization and fair bandwidth sharing in high bandwidth-delay product (HBDP) networks. We present a new insight into the TCP congestion control problem; in particular an end-to-end delay-based approach for an HBDP network. Our main focus is to design an end-to-end mechanism that can achieve the goal without the assistance of any network feedback. Without a router's aid in notifying the network load factor of a bottleneck link, we utilize goodput and throughput values in order to estimate the load factor. The obtained load factor affects the congestion window adjustment. The new protocol, which is called TCP-goodput and throughput (GT), adopts the carefully designed inversely-proportional increase multiplicative decrease window control policy. Our protocol is stable and efficient regardless of the link capacity, the number of flows, and the round-trip delay. Simulation results show that TCP-GT achieves high utilization, good fairness, small standing queue size, and no packet loss in an HBDP environment.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.6 no.2
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• pp.34-41
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• 1997

The objective of this study is to investigate experimentally the frequency characteristics of the hole tones generated by a circular jet of low speed impinging on a plate with a round hole. The experimental results about the sound spectrum and the time wave of the hole tone are presented and discussed in relation with the hole type, the jet velocity and the distance of the nozzle-to-plate with a round hole. From the sound spectrum and time wave measurements, it is found that the hole tone is generated not only by an interaction of convected vortices with a round hole but also by a series of vortex shedding from jets passing through a hole. The hole tones generated by a feedback mechanism consist of many frequency stages and also have a hysteresis phenomenon like an edge tone. But the hole tones generated by a series of vortex shedding have nothing with the stage characteristics. The frequencies of hole tones are influenced by the jet velocity, the distance of the nozzle-to-plate with a round hole and the hole type.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2000.10a
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• pp.95-98
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• 2000

The rapid expansion of the WWW is well known and has huge potential for enabling companies, large and small, to gain new marketplaces globally at low cost, or to be disintermediated by others doing so. A totally new competitive environment opening up new opportunities is upon us. As a result, the electronic commerce is growing quickly and the importance of electronic marketplace is emphasized. From the view of SCM, applying the business-to-business electronic commerce to the relationship between firms is expected to make major changes. This study focuses on the effects of the introduction of web-based purchasing systems on the buyer-supplier relationship. We conduct a case study on the Korean firms The major findings of this study are summarized as follows. First, in introductory phase, some buying firms fail to design the appropriate mechanism for business relationships. It can weaken the cooperation between buyers and suppliers. Second, for critical or customized parts, it is possible to gather the information about potential suppliers and to make business relations using it. Third, using web-based purchasing systems, capable suppliers can take more opportunities to leverage its competence for business relations. So we can expect the positive feedback.