• 한국측량학회지
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• 제32권3호
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• pp.245-251
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• 2014

As delineating market areas of retail businesses has become an interesting topic in marketing field, Lee and Lee recently suggested a noteworthy method, which applied the hydrological analysis of geographical information system (GIS), based on Christaller's central place theory. They used a digital elevation model (DEM) which inverted the kernel density of retail businesses, which was measured by using bandwidths of pre-determined 500, 1000 and 5000 m, respectively. In fact, their method is not a fully data-based approach in that they used pre-determined kernel bandwidths, however, this paper has been planned to improve Lee and Lee's method by using a kind of data-based approach of the L-index that describes clustering level of point feature distribution. The case study is implemented to automobile-related retail businesses in Seoul, Korea with selected Kernel bandwidths, 1211.5, 2120.2 and 7067.2 m from L-index analysis. Subsequently, the kernel density is measured, the density DEM is created by inverting it, and boundaries of market areas are extracted. Following the study, analysis results are summarized as follows. Firstly, the L-index can be a useful tool to complement the Lee and Lee's market area analysis method. At next, the kernel bandwidths, pre-determined by Lee and Lee, cannot be uniformly applied to all kinds of retail businesses. Lastly, the L-index method can be useful for analyzing the space structure of market areas of retail businesses, based on Christaller's central place theory.

• 대기
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• 제18권2호
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• pp.97-109
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• 2008

The aerosol characteristics in terms of 4 different cases (Asian dust, fog, clear sky and cloud) which had happened at Anmyeon Island in April 2006 were studied using various measurements such as the Micro Pulse Lidar (MPL), sunphotometer, $\beta$-ray $PM_{10}$ Analyzer, anemoscope and anemometer. In addition, synoptic charts, back trajectory analyses and satellite images were also used to help characterize the aerosol events. The aerosol optical properties were featured by the Aerosol Optical Depth (AOD) and ${\AA}ngstr\ddot{o}m$ exponent which were estimated by the sunphotometer. When Anmyeon Island was dominated by the Asian dust, the AOD was sharply increased as seven times as a yearly average of it (0.35). As compared with a yearly average of the ${\AA}ngstr\ddot{o}m$ exponent of 0.97, the ${\AA}ngstr\ddot{o}m$ exponent of a dust day was significantly low (0.099). In addition, $PM_{10}$ mass concentration showed an extremely high record. The maximum concentration reached $1790.5{\mu}gm^{-3}$ on 8 April 2006. The maximum mass concentration was shown with delay when the wind speed of $0ms^{-1}$ was observed. It was also found that a satellite image of the MODIS-RGB had a good agreement with the results of those measurements. It was shown that the MPL was able to describe effectively the vertical distribution of aerosol for all the cases. In particular, the MPL evidently captured the aerosol layer before the cloud observation. The aerosol layer was similarly described by the AOD. On a clear sky day, the AOD had not only a very low value (0.054) but also a feature of homogeneity.

• Advances in pediatric surgery
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• 제14권2호
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• pp.164-172
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• 2008

The survival rate for rhabdomyosarcoma (RMS) has significantly improved after the introduction of combined multimodality treatment. We report the 20-year treatment outcome of pediatric rhabdomyosarcoma in a single institution. The medical records of 16 patients treated for rhabdomyosarcoma between December 1986 and August 2007 at the Department of Pediatric Surgery, Seoul National University Children's Hospital, were retrospectively reviewed. Mean age at diagnosis was 7.1 years (range: 1.3 -14.2 years). Retroperitoneum was the most common primary site (n=7, 43.8 %), and embryonal type was predominant (n=11, 6 %). Before the treatment, most patients were in advanced TNM stage (stage III 50 %, IV; 25 %). The patient distribution according to the Intergroup Rhabdomyosarcoma Study Clinical Grouping System (IRS-CGS) was as follows; Group I 31.3 %, Group II 12.5 %, Group III 31.3 % and Group IV 25 %. Patients were classified into three groups according to the extent of resection of the primary tumor; complete resection (CR, n=5; 31.3 %), gross total resection (GTR, n=7; 43.8 %) and incomplete resection (IR, n=4; 25 %). Recurrence was observed in 9 patients (56.3 %) while there was no recurrence in CR patients. All patients with recurrence were identified as moderate or high-risk according to the IRS-V Risk Group. Pre-treatment TNM stage of RMS in our institution was advanced with aggressive clinical feature, however postsurgical conditions according to IRS-CGS were similar to the previous reports by IRS. This suggests that down-staging of IRS-CGS was achieved with multimodality treatment with CR or GTR. It also suggests that complete resection is the most important prognostic factor in the treatment of RMS in children. Patients classified as moderate or high-risk need close follow-up due to high recurrence rate. In case of localized recurrence, better outcome may be achieved with multimodality treatment including limited surgery.

• 천문학회보
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• 제36권2호
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• pp.143.1-143.1
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• 2011

Deep Ca,b,y images obtained from the CTIO 4m Blaco telescope are used to investigate the multiple stellar populations of red giant branch (RGB) and sub-giant branch (SGB) in Galactic globular clusters NGC 6656 and NGC 6723. For NGC 6656, confirming the result of Lee et al. (2009), we find two discrete populations of the RGB stars of which mean color separation is about 0.2 mag in hk[=(Ca-b)-(b-y)] index. Furthermore, we also find the bimodel distribution of the SGB stars in (hk, y) color-magnitude diagram. A new finding is that the (hk, y) color-magnitude diagram of NGC 6723 shows two distinct RGB stars with different calcium abundances of which mean color separation is about 0.12 mag in hk index. This multiple stellar feature has not been observed in previous observation, suggesting that NGC 6723 may also be a possible relic of dwarf galaxies that merged into the Milky Way in the past. Thus our result adds further constraints to the merging scenario of the Galaxy formation. Unfortunately, the split of SGB stars in NGC 6723 is not obvious. We will present some statistical results to compare properties of two populations in two clusters.

• 수산해양교육연구
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• 제23권3호
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• pp.477-485
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• 2011

For the identifying of spatial distribution pattern, Moran's Index(I) which has the range of values from -1 to +1 is common method for the spatial autocorrelation measurement. When I is close to 1, all neighboring features have close to the same value, indicating clustered pattern. Conversely, if the spatial pattern is dispersed, I is close to -1. And I closing to 0 means spatially random pattern. However, this index equation is influenced by how defining the neighboring features for target feature. To compare and understand the difference of neighborhood definition methods, fixed distance neighboring method and Gabriel Network method were used for I. In this study, these two methods were applied to two marine environments with water quality data. One is Gwangyang Bay which has complex geometric coastal structure located in South Sea of Korea. Another is Uljin area adjacent to open sea located in east coast of Korea. The distances between water quality observed locations were relatively regular in Gwangyang Bay, however, irregular in Uljin area. And for the fixed distance method popular Arc GIS tool was used, but, for the Gabriel Network, Visual Basic program was developed to produce Gabriel Network and calculate Moran's I and its Z-score automatically. According to this experimental results, different spatial pattern was showed differently for some data with using of neighboring definition methods. Therefore there is need to choose neighboring definition method carefully for spatial pattern analysis.

• Journal of Ginseng Research
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• 제38권4호
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• pp.233-238
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• 2014

Background: The actin cytoskeleton in podocytes is essential for the maintenance of its normal structure and function. Its disruption is a feature of podocyte foot-process effacement and is associated with proteinuria. ${\alpha}$-Actinin-4 in podocytes serves as a linker protein binding the actin filaments of the cytoskeleton. Methods: To investigate the effect of ginseng total saponin (GTS) on the pathological changes of podocyte ${\alpha}$-actinin-4 induced by diabetic conditions, we cultured mouse podocytes under normal glucose (5mM) or high glucose (HG, 30mM) conditions, with or without the addition of advanced glycosylation end products (AGE), and treated with GTS. Results: In confocal imaging, ${\alpha}$-actinin-4 colocalized with the ends of F-actin fibers in cytoplasm, but diabetic conditions disrupted F-actin fibers and concentrated ${\alpha}$-actinin-4 molecules at the peripheral cytoplasm. GTS upregulated ${\alpha}$-actinin protein in a time- and dose-dependent manner, and suppressed the receptor for AGE levels in western blotting. Diabetic conditions, including HG, AGE, and both together, decreased cellular ${\alpha}$-actinin-4 protein levels at 24 h and 48 h. Such quantitative and qualitative changes of ${\alpha}$-actinin-4 protein induced by diabetic conditions were mitigated by GTS. Conclusion: These findings imply that both HG and AGE have an influence on the distribution and amount of ${\alpha}$-actinin-4 in podocytes that can be recovered by GTS.

• 한국동물학회지
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• 제35권2호
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• pp.149-160
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• 1992

Using the protein A-gold complex, the mvoabrillogenesis and actin localization of cultured myoblast were invastisated. In the superstructural changes of mvogenic cell during differentiation, pectoral myoblasts contained large nucleus and numerous ribosomes but no myofibrils during the first 24 hr of cultures. Mvoblast initiated to differentiate at 3-day of culture contained the primitive myofibrillar structure. At 96 hr of culture, the mvofibrillar structure showed reletively discernable Z band but pools defined A, H and M bands. The feature of sarcomeric structure showed more defined form at cultur 5 day. In the aspect of actin localization, actin wvas diffusely detected throughout the cytoplasm of myogenic cell and nucleus during the proliferating stage. At 72 hr of culture, with the appearantc oi primitive mvofibrils, gold particles were observed in surrounding of myofibrils but still presented in overall of cytoplasm, especially in the surface and lumen of endoplasmic reticulum. With the gradual increase of culture time, local distribution of actin was readily detected within cytoplasm. In the 5-day specimen of cultures, gold particles precisely indicate the sites of actin localifation within the sarcomere. These results indicate the time of onset of myofibrill appearance and the biosynthetic and incorporation pathway of actin molecules into sarcomeric structure during myofibrillogenesis. Thus, in the present study, the first mvoabrillar structure was detected at culture 3 day, and the initiation of assembly into a typical sarcmeric structure was observed at culture 5 day. It seems, however, that the course of events on myofibrillogenesis of cultured myoblasts can be changed with great dependence of culture conditions including the number and groluth rate of mononucleated mvoblasts after seeding although the fundamental process shows identical appearances.

• 한국습지학회지
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• 제22권4호
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• pp.321-327
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• 2020

산업발전과 인구증가, 생활수준의 향상으로 하·폐수 발생량 및 하수처리장 연계처리수가 매년증가 하고 있다. 연계처리수는 저유량 고농도의 특징을 가지고 있다. 따라서 하수처리장 운영에 큰 영향을 미치고 연계처리수를 처리하기 위해 많은 비용도 사용되는 것으로 나타났다. 본 연구에서는 연계처리수의 유입 유량을 개별 반응조로 전량 유입시킬 경우 방류수 수질이 적게 상승한 시나리오를 도출했고, 모델링 결과 유입하수, 무산소조에 유입시킬 경우 방류수 수질이 가장 적게 상승하는 것을 확인할 수 있었다. 이와 같은 결과를 바탕으로 연계처리수의 유입 유량을 유입하수와 무산소조로 분배하여 유입시킬 경우에 대하여 분배 비율에 대한 다양한 시나리오를 생성했다. 다양한 시나리오를 통해 모델링을 진행한 결과 유입하수(80%), 무산소조(20%)의 비율로 연계처리수의 유입유량을 분배 유입 시킬 경우 TN, TP의 수질이 가장 적게 상승하는 것으로 나타났다.

• 한국어류학회지
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• 제20권1호
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• pp.7-12
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• 2008

돌마자 M. yaluensis 정자의 변형과정과 성숙한 정자의 미세해부학적 구조를 전자현미경으로 관찰하였다. 돌마자 정자형성과정에서 발생되는 편모는 핵의 한쪽 측면에서 발생하여 계속 신장되고 있어 잉어과 정자변형과정과 공통된 type 2로 분류할 수 있으며 성숙한 돌마자 정자의 두부 측면에 위치한 편모구조는 정자변형과정에서 핵의 회전이 일어나지 않았다는 것을 입증하고 있다. 두 중심립의 각도만큼 편모와 두부의 각도가 만들어지며 잉어과 어류 정자에서 두부와 편모는 두 중심립의 각도만큼 기울어져 있었다. 정자변형과정 중에 중심립 주변에서 관찰되는 골지체는 편모의 확장과 핵와 안으로 이동하는 데 필요한 물질을 제공하는 것으로 추정되며 정자변형과정 후기에는 관찰되지 않았다. 돌마자 정자의 세포질에서 나타나는 vesicles 구조는 중편보다 편모에서 많이 분포하며, 정자 편모의 vesicles은 기부에 주로 분포해 있으며 말단부에서는 나타나지 않는다. 중편세포질에 분포하는 미토콘드리아는 비대칭적으로 분포해 있으며, 미토콘드리아의 비대칭적 분포는 잉어류에서는 일부 종을 제외한 공통적인 특징인 것으로 사료된다.

• 복식문화연구
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• 제10권5호
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• pp.542-554
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• 2002

The purposes of this study were to investigate, analyze, and consider the feature and practical situation of Apparel CAD education and distribution situation of CAD system so that CAD education can be effectively operated and managed in various kinds of relevant schools and universities. 32 colleges and universities that are performing CAD educational system are selected for the study. The author of the study has investigated and obtained the information through questionnaires to 32 professors who are in charge of CAD lectures and 301 students who are receiving CAD education. The result is as follows. 1. It showed that 62.5% of CAD educational systems have been practically introduced after 1995. Regarding the using system, YUKA occupies 46.9%, PAD 21.8%, and GERBER 18.8% and these three kinds of system have been chiefly supplied. 40.6% of them own only one system, 37.5% of them own 2～5 systems and 78% of them own less than 5 systems. 2. The most seriously pointed problems during the operation of CAD system were the lack of experimental materials and the frustration of manpower supply. Thus, the CAD education programs in schools and universities are practiced in inferior environments internally and externally. 3. Regarding the practical situation of CAD education, 28 among 32 schools and universities are performing CAD as one of the regular subjects for the curriculum. 4. Regarding satisfaction degree of the using system, professors showed higher satisfaction degree than students did. In conclusion, it showed that although the practical situations of CAD education in schools and universities have been changed and improved so much since 1995 owing to the increase of the positive recognition of the necessity of CAD, many students in the educational sites cannot study their favorite subjects related with CAD program with interest due to the lack of experimental facilities, the poor computer management systems, and the problems of manpower supply, etc.