• Title/Summary/Keyword: Family demand

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Glutamine Deprivation Inhibits Invasion of Human Prostate Carcinoma LnCap Cells through Inactivation of Matrix Metalloproteinases and Modulation of Tight Junctions (글루타민 결핍에 따른 Tight Junction 및 MMPs 활성 조절을 통한 전립선 암세포의 침윤 억제 현상)

  • Shin, Dong Yeok;Choi, Yung Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.8
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    • pp.1167-1174
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    • 2013
  • Cancer cells exhibit increased demand for glutamine-derived carbons to support anabolic processes. Indeed, the spectrum of glutamine-dependent tumors and the mechanisms through which glutamine supports cancer metabolism remain areas of active investigation. In the present study, we investigated the effects of glutamine deprivation on the correlation between tightening of tight junctions (TJs) and anti-invasive activity in human prostate carcinoma LnCap cells. Glutamine deprivation markedly inhibited cell motility and invasiveness in a time-dependent manner. The anti-invasive activity of glutamine deprivation was associated with an increased tightness of the TJ, which was demonstrated by an increase in transepithelial electrical resistance (TER). The activities of matrix metalloproteinase (MMP)-2 and MMP-9 were inhibited in a time-dependent fashion by glutamine deprivation, which was correlated with a decrease in expression of their mRNA and proteins and up-regulation of tissue inhibitors of metalloproteinases (TIMPs) expression. Furthermore, glutamine deprivation repressed the levels of the claudin family members, which are major components of TJs that play a key role in the control and selectivity of paracellular transport. Moreover, the levels of E-cadherin, a type I transmembrane glycoprotein, and snail, an epithelial to mesenchymal transition regulator and zinc finger transcription factor, were markedly modulated by glutamine deprivation. Taken together, these findings suggest that TJs and MMPs are critical targets of glutamine deprivation-induced anti-invasion in human prostate carcinoma LnCap cells.

A Study on Nursing Students의 Attitudes toward the Elderly (노인에 대한 간호대학생의 태도조사 연구)

  • 김은일
    • Journal of Korean Academy of Nursing
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    • v.12 no.1
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    • pp.1-12
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    • 1982
  • Presently, there is increasing demand for geriatric nursing care due to increasing proportion of elderly population and extended age. And, of particular importance in deforming the effectiveness of nursing care given to the elderly is the attitude of nursing personnel toward the elderly patient. This study was intendent to investigate the attitudes of baccalaureate nursing students toward the elderly, and to investigate any possible correlation between these attitudes and the following variables: the students' levels (freshman, sophomore, junior, senior), their preferences for var-ious fields of specialization in nursing after graduation, their clinical experiences with geriatric-patients, their personal experience with elderly family members, their educational experience of the elderly's health problems and geriatric nursing, and their experience with relatives and acquaintances over 60 years of age. Therefore, the purpose of this study was to compile basic data about the attitudes of nursing students toward the elderly in order to contribute to the improvement of geriatric nursing. The subjects for this study were 259 nursing students: 163 in the College of Nursing at E-womans University., and 96 in the Department of Nursing in K. College. Data was collected from the 11th of Sep., to the 8th of Oct., 1981, using the Tuckman-Lorge Attitude Questionnaire which contained 131 items excepting 6 items. The attitudes toward the elderly was scored by the use of mean and standard deviation. The relations between attitudes toward the elderly and six independent vairables were analysed by T-test. The results which were obtained are as follows : 1. The attitude score of nursing students was M=71.67 S.D= 16.18. Nursing students agreed with 54.8% of the stereotypic statements, and they had stereotypic attitudes toward the elderly relatively. (P<0.01). 2. There was a significant difference between the attitudes of nursing students toward the elderly, and sophomores had a less stereotypic attitudes than juniors and seniors (P<0.01). 3. There was significant difference between the attitudes toward the elderly and the preferences for various fields of specialization in nursing after graduation, and nursing students those who wanted maternity fields had a more stereotypic attitudes than others (P<0.05, p<0.01). 4. There was no significant difference between the attitudes toward the elderly and the clinical experience with the geriatric patients (P>0.05). 5. There was no significant difference between the attitude3 toward the elderly and the personal experience with elderly family members (F>0.05). 6. There was no significant difference between the attitudes toward the elderly and the educational experience of the elderly's health problems and geriatric nursing (P>0.05). 7. There was no significant difference between the attitudes toward the elderly and the experience with relatives and acquaintances over 60 years of age (P>0.05).

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A study on the package design approach on sensitive (감성소구에 있어서 포장디자인 연구- 베이커리 제품 중심으로)

  • 장욱선
    • Archives of design research
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    • v.14 no.2
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    • pp.117-126
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    • 2001
  • Dietary life is said to be consummated even to a phase of art from phase of survival, recognition, selection and preference. Dietary life, from a sheer earing, is now transforming itself into a joy, and therefore, function of foodstuff packaging demand diversification rather than a simple packaging. Recently, socio-economic environment is showing conspicuous changes in that there are increasing number of working couples nuclear family, old-age population, social activity and improvement of living standards. Such a change in the living environment has much impact on our dietary life. Particularly, an age when cake and cookies of western origin were all but strange is gradually phasing out, while it is deemed to be improper to overlook the fact that bread and cakes are solidifying their position as part of foodstuff meanies for on dietary life. Of cakes and cookies, cakes have come to enjoy a position whereby they are regarded as part of an imperative for family banquets, various get-together and birthday celebration, etc., with a significant improvement that caters to our taste vis-a-vis an stage of introduction of cakes. At the time when reined foreign bakeries, one after another , are contemplating to make an inroad into Korea, and when the distribution market is to be opened fully in July of 1993, Korea bakeries that have been building up their position within the domestic market are expected to face a considerable number of difficulties. Accordingly, under such circumstances of the time text we are in it is attempted in this study to map out measures that may contribute to the strengthening of the products of business enterprises and improvement of corporate image that may appeal to feeling and emotions of consumers packaging that could attain objectives, and package design planning that, as an important factor for playing its own share in the restoration of humanism that is being alienated, may appeal to consumer sensitivity, rather than packaging that is being utilized merely as tool designed for marketing

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Modular Building for Urban Disaster Housing: Case Study of Urban Post-Disaster Housing Prototype in New York

  • Ford, George;Ahn, Yong Han;Choi, Don Mook
    • Fire Science and Engineering
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    • v.28 no.6
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    • pp.82-89
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    • 2014
  • Disasters that destroy homes and infrastructure and cause significant financial damage are becoming more common as population centers grow. In addition, several natural disasters have resulted in a major loss of life and created countless refugees due to damage to housing. After major catastrophic disasters, it is very important that the government agencies respond to post-disaster housing issues and provide resources such as temporary housing before the full rehabilitation and reconstruction of destroyed and damaged housing. To provide affordable temporary housing for residents who may lose their homes as the result of a catastrophic disaster including storms, government agencies must develop a post-disaster housing prototype. In general, government agencies should explore several different forms of factory-built single-story, single family housing, such as modular homes, panelized homes, and precut homes. In urban cities including New York and Seoul, it is very important to provide housing which supports the demand for higher-density living spaces than single-family homes or trailers typically available due to the high population density and the desire to resettle as many residents as possible in their former neighborhoods. This study identified the urban post-disaster housing prototypes that may provide higher density housing with high quality living spaces, high air quality, and energy efficiency as well as rapid deployment. A case study of "Urban Post-Disaster Housing Prototype Program in New York" was conducted through a detailed interview process with a designer, engineer, contractor, the Office of Emergency Management (OEM) in New York, the U.S. Army Corps of Engineers (USACE), and temporary occupants. An appropriate disaster housing program that can provide living spaces for victims of disasters that keeps residents in their community and allows them to live and work in their neighborhoods was developed.

A Gender-Sensitive Approach on Home Economics in Secondary Education (중등 가정과 교육의 성격에 관한 성인지적 접근)

  • 정해숙
    • Journal of Korean Home Economics Education Association
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    • v.15 no.2
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    • pp.55-66
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    • 2003
  • In Korea home economics in the secondary school level was only taught to girls until 1995. So. home economics education only for girls was criticized to sexist education by the feminists. According to the 6th revision of curriculum. home economics has been taught to girls and boys. But some of curriculum developers raises another questions on home economics education. They argue that home economics is a subject which prepares students for the demand of their day-to-day lives. but they can manage their lives well without school learning. The purpose of this study is to explore the educational values of home economics in secondary education from the gender-sensitive approach. For this study, a literature survey on the nature of home economic education in secondary education and the content analysis on 12 secondary school textbooks of Home Economics were employed. The results are as follows : First, the educational values of home economics education should not be underestimated. The aims of home economics education is to help students grew into a independent person by managing their daily lives. The home is charged with fostering a side of our life which we might call Personal, private. intimate and nurturing. The management of the home needs good skills and attitudes. and many knowledges on the child rearing, family relation, marriage, love and sex, which can not be successfully acquired without school learning. And home economics education for boys and girls can help break down the barriers between the sexes because it can change the attitudes of students regarding the private sphere. which is traditionally where women have worked. Second. most of contents of Home Economics were composed of the women-oriented contents. There was a trend still describing that domestic labor mainly be carried out by mother. And the ideas that only the family consisting of two parents and their children is normal were founded. Finally directions of development of the Home Economics Education are suggested.

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An Alternative Improved-Layout of Rural House Plot (농촌주택의 주거 공간구조 개선방안)

  • 박장혁
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.41 no.6
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    • pp.54-63
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    • 1999
  • Considering that rural village had evolved through a long-sustained effort of harmnization with nature, there should be the wisdom not only to reflect the level of rural resident's housing demand, but also to conserve the traditional characteristics of high-valuation in the modern rural housing. In Korea , standard design proposals of rural houses had been made public three times ; in 1972 , 1984 and 1995. so , firstly, this study analysed the inner-space layouts of design proposals mentioned above, from which changes and problems in the past housing design were derived. And also, through, the positive acceptance of residents' opinion living inthe houses built by standard design proposals in 1970 ~1980's, improved design principles and an alternative model were proposed , finally. The inner-space structed of standard design proposals in 1970s was originated from small-scaled and low-priced one, basically under the " open system". In 1980s, the basic design principle changed to the 'closed system' in which the living room being the focus of indoor family life, and , in 1990s, progressively, therural housing developed to the high qualified type by the spatial enlargement and with increased equipements. However, this structural change of rural house brought about the problem of functional separatioon between farming and daily living activities. In details, limited spaces of multipurpose spaces and sanitary facility would be mentioned as problems for improvement. conclusively in this study, newoly arranged "open system" was recommended , as a basic design principle for theinner space structure formation of rural house, which easily links the constituent inner-house spaces to outer one. Based on this principle, the detailed design criterial was proposed as follows ; 1. The living room be directly linked to the front-yard and centrally placed, the addtional space of which could be secured for the special family events by the flexibleuse of its adjacent room or by the housing of male quarters(separated from main building quarter). 2. The kitchen also be directly linked to side-yard and to livng room , for the convenience of farming activities and the shortening of path flow housewife. 3. The expanded toilet-and-bathroom be placed in the directly connected left-hand side to the living room and also be allowed access through multipurpose spaces to out door. 4. The multipurpose spaces be directly connected to the kitchen and the toilet and-bathroom , of which function would be for undressing of working clothes, quickwashing and ordinary working.nd ordinary working.

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Application of the Development Model of Day Care Center for Dementia (치매주간보호사업 개발모형의 적용)

  • Chung, Yeun-Gang;Baik, Kyung-A;Hyun, Hye-Young;Yeoum, Soon-Gyo;Kim, Kyung-Hee;Choi, Mi-Hye;Han, Sung-Hee
    • Research in Community and Public Health Nursing
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    • v.14 no.1
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    • pp.106-119
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    • 2003
  • This study was executed to develop the model of the format of the day care center which supplies the total service on the health care in the day time and social program related with the work and to evaluate the processing courses which was adjusted for 3 years from March 1999 to December 2001 in order to improve the quality of life of the family who experience dementia, dementia prevention, and the old and the burden of daily activities. The processing courses of this business model were evaluated to the confirmation on the health condition, application of the nursing processes, and the precise medical examination, and 20 sorts of social programs. The methods used in this model were the simplified MMSE-K, Ability for ,Daily Life(ADL), Instrumental Activities of Daily Living(IADL), and nursing process, and so on. The execution effects of this model are as follows. 1. It can contribute to the delay in the dementia process of the old people who are related with the dementia and maintenance and improvement of the health by confirming the stopping of the process of the dementia as the objective estimation method while the dementia symptom is maintained as the current condition through the medical and social total services. 2. The reduction of the burden for the daily care of the subject people and their families for the old people who are concerned with the dementia helped to improve the quality of life of the subject people and their family by enabling them to have jobs. 3. It enabled them to positively cope with the demand for the health and nursing of the local residents related to the old people. 4. It enabled them to enhance the recognition for the socialization of the local social organization and residents for the old people. 5. It enabled them to reinforce the related system among the local social organizations, and develop and provide the various social programs which are proper for the old people.

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Dietary and Health Behaviors and Nutrition Education Environments of High School Students in Gwangmyeong, Gyeonggi Province (고등학생의 식습관과 건강행동 및 영양교육 상태 -경기 광명지역을 중심으로-)

  • Rhie, Seung Gyo;Jun, JinSun
    • The Korean Journal of Community Living Science
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    • v.26 no.2
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    • pp.287-301
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    • 2015
  • This study provides basic data for the development of nutrition education programs for high schools by examining adolescents' demand for nutrition education and their dietary and health behaviors. A survey was conducted for 500 students attending two high schools in the Gwangmyeong area. The questionnaire addressed their dietary habits, health behaviors, and nutrition education. In terms of meal conditions, 70.6% of all respondents had meals at least four times a day, 67.2% skipped breakfast frequently, and only 29.9% had breakfast with their family members. In addition, 66.0% reported a slightly unbalanced diet depending on the food (35.1% for vegetables and 28.2% for legumes). Nutrition labeling was checked occasionally (44.4%) by male respondents and surely (39.3%) by female respondents (p<0.01). In terms of health behaviors, 67.4% of male respondents reported a lack of sleep (5-7 hours), 33.3% of male respondents reported exercising three to four times a week, and 42.7% of female respondents reported no exercise. For the level of stress, 58.9% of male respondents reported "sometimes", and 43.0% of female respondents reported "always". For interest in nutrition education, 58.3% of the respondents reported "no". A majority of the respondents learned about nutrition through "the media or the Internet" (89.6%). The health behavior score was significantly carelated with dietary habits (p<0.01) and the stress score (p<0.05) for male students, and it was negatively correlated with checking nutrition labels (p<0.01) and positively correlated with the BMI for female students. These results suggest that appropriate health behaviors can help overcome stress and produce better dietary habits for male students, but for females, the results are ambiguous. A majority of the respondents (57.9%) perceived a need for nutrition education as part of the high school curriculum, and the content of such a curriculum included more meals with family members and the importance of breakfast. Based on the results, nutrition education for male students should focus on nutrition labeling, whereas that for female students, on exercise frequency and proper weight management.

Research on Development of a Customized Nursery School for Nurses (간호사를 위한 맞춤보육어린이집의 개발에 관한 연구)

  • Kang, Ki-Seon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.3
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    • pp.407-416
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    • 2019
  • This study is about a Customized Nursery School where working women can support work - life balance and a reduction in retirement or turnover. The research method is to identify the current status of Customized Nursery services and to recognize the recognition and need of the operation of Customized Nursery School. The importance of securing skilled nurses and preventing them from changing their jobs for the health and safety of people cannot be emphasized enough. A Customized Nursery School must be opened to reduce the retirement or change of jobs of working women nurses and to provide care for continuous work in three shifts from 365days to support the balance between the working mother and family. It is considered that nurses will put their children in relief when using retired nurses who have the ability to work 24hour rotation in a Customized Nursery School and when a Customized Nursery School be ran suited for the condition and demand of working women nurses, it is expected to reduce retirement and the change of jobs, also to give positive effect on marrige and family planning which would make improvement in low birthrate. To activate the Customized Nursery School, Creating a secure learning environment and qualification of educators great effort should be put. A program curriculum based on 'basic life and habits' should be the center of education. Continuous management and effort will need to be placed in continuous development of educators.

The Short-Hours Part-Time Jobs in Korea (한국의 초단시간 노동시장 분석)

  • Moon, Ji-Sun;Kim, Young-Mi
    • Korean Journal of Labor Studies
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    • v.23 no.1
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    • pp.129-164
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    • 2017
  • This article is an exploratory study on the recent growth of short-hours part-time work in Korea. The short-hours part-time work has been rapidly growing among low-educated women over sixty, particularly among bereaved or divorced women, contrary to the expectation of the government that encouraged the part-time work by means of work-family balance for working mothers or middle-aged women who experienced career interruption. The short-hours part-time jobs are concentrated in social service industry, mostly elderly care service jobs, and their working conditions are extremely poor, mostly low-wage jobs with no social insurances except for health insurance. In this study, we discuss why the short-hours part-time work has grown so fast in Korea since the mid 2000s. Using various governmental statistics, we examine the effects of the labor demand and supply situations during the time period, the legal context that is related with the exempt clause of the labor law, and the institutional context related with the government's public job creation projects for the elderly. We suggest some public policies needed to slow down the growth of the short-hours part-time jobs and to elevate their working conditions.