• Title/Summary/Keyword: Fall-of-potential method

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Prediction of an Essential Gene with Potential Drug Target Property in Streptococcus suis Using Comparative Genomics

  • Zaman, Aubhishek
    • Interdisciplinary Bio Central
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    • v.4 no.4
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    • pp.11.1-11.8
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    • 2012
  • Genes that are indispensable for survival are referred to as essential gene. Due to the momentous significance of these genes for cellular activity they can be selected potentially as drug targets. Here in this study, an essential gene for Streptococcus suis was predicted using coherent statistical analysis and powerful genome comparison computational method. At first the whole genome protein scatter plot was generated and subsequently, on the basis of statistical significance, a reference genome was chosen. The parameters set forth for selecting the reference genome was that the genome of the query (Streptococcus suis) and subject must fall in the same genus and yet they must vary to a good degree. Streptococcus pneumoniae was found to be suitable as the reference genome. A whole genome comparison was performed for the reference (Streptococcus pneumoniae) and the query genome (Streptococcus suis) and 14 conserved proteins from them were subjected to a screen for potential essential gene property. Among those 14 only one essential gene was found to be with impressive similarity score between reference and query. The essential gene encodes for a type of 'Clp protease'. Clp proteases play major roles in degrading misfolded proteins. Results found here should help formulating a drug against Strptococcus suis which is responsible for mild to severe clinical conditions in human. However, like many other computational studies, the study has to be validated furthermore through in vitro assays for concrete proof.

A Study on Grounding Resistance Measurement of Power Supplying Substation using Grounding Current Division Factor and FOP Profile Method (접지전류 분류계수 및 전위강하곡선법을 이용한 운전 중인 변전소의 접지저항 측정 방법에 관한 연구)

  • An, Yong-Ho;Choi, Jong-Ki;Kim, Yong-Hak;Han, Jeong-Yeol;Lee, You-Jin;Han, Byoung-Sung
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.25 no.6
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    • pp.100-107
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    • 2011
  • Since transmission and distribution neutral wires are connected with a substation grounding grid, it is very difficult to measure grounding resistance of isolated substation grounding grid after the substation is energized. It is impractical to isolate the grounding grid from other parallel connections such as distribution line neutrals and overhead ground wires for grounding resistance measurement only. In this paper, we proposed and demonstrated a novel measurement method of grounding resistance of isolated substation grounding grid. For this method, grounding current division factor and conventional FOP(Fall-Of-Potential) profiles were measured at power supplying 154[kV] substation. The obtained FOP profile was processed with the measured grounding current division factor to produce the grounding resistance of isolated grounding grid. Simulated FOP profile agreed well with the measured one showing the validity of the proposed method.

Video Compression Method Using SURF Feature and Block Shaping (SURF 특징과 블록 모양을 이용한 동영상 압축 방법)

  • Jun, Jae-Hyun;Kim, Min-Jun;Jang, Yong-Suk;Ahn, Cheol-Woong;Kim, Sung-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.4
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    • pp.161-167
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    • 2015
  • Today, computer network infrastructure is commonplace and internet user increase. Transmission bandwidth for network traffic is increasing. The data amount of 2014 and 2015 year measured 47 and 62 exabyte, it shows a tremendous increase. Video traffic occupy 60 percent among internet traffic. Enormous growth of Internet traffic than the network infrastructure is not enough to support them, so mobile network occur side-effects such as fall of voice communication. In this paper, we proposed the video compression method using SURF feature and block shaping in order to avoid potential damage. Our proposed method can provide enough performance than previous method.

Effects of Muscle Activation Pattern and Stability of the Lower Extremity's Joint on Falls in the Elderly Walking -Retrospective Approach- (노인 보행 시 하지 근 활동 양상과 관절의 안정성이 낙상에 미치는 영향 -후향성 연구-)

  • Ryu, Jiseon
    • 한국체육학회지인문사회과학편
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    • v.57 no.3
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    • pp.345-356
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    • 2018
  • Objective: The purpose of this study was to investigate the local stability of the lower extremity joints and muscle activation patterns of the lower extremity during walking between falling and non-falling group in the elderly women. Method: Forty women, heel strikers, were recruited for this study. Twenty subjects (age:72.55±5.42yrs; height:154.40±4.26cm; mass:57.40±6.21kg; preference walking speed:0.52±0.17m/s; fall frequency=1.70±1.26 times) had a history falls(fall group) within two years and Twenty subjects (71.90±2..90yrs; height:155.28±4.73cm; mass:56.70±5.241kg; preference walking speed: 0.56±0.13m/s) had no history falls(non-fall group). While they were walking on a instrumented treadmill at their preference speed for a long while, kinematic and EMG signals were obtained using 3-D motion capture and wireless EMG electrodes, respectively. Local stability of the ankle and knee joint were calculated using Lyapunov Exponent (LyE) and muscles activation and their co-contraction index were also quantified. Hypotheses were tested using one-way ANOVA and Mann-Whitey. Spearman rank was also used to determine the correlation coefficients between variables. Level of significance was set at p<.05. Results: Local stability in the knee joint adduction-abduction was significantly greater in fall group than non-fall group(p<.05). Activation of anterior tibials that acts on the foot segment dorsal flexion was greater in non-fall group than fall group(p<.05). CI between gastrocnemius and anterior tibials was found to be significantly different between two groups(p<.05). In addition, there was significant correlation between CI of the leg and LyE of the ankle joint flexion-extention in the fall group(p<.05). Conclusion: In conclusion, muscles that act on the knee joint abduction-adduction as well as gastrocnemius and anterior tibials that act on the ankle joint flexion-extention need to be strengthened to prevent from potential fall during walking.

Transient impedance characteristics of counterpoise according to the soil structures (대지구조에 따른 매설지선의 과도접지임피던스 특성)

  • Lee, Bok-Hee;Li, Feng;Jung, Dong-Cheol;Kim, Ki-Bok;Cho, Sung-Chul
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2009.10a
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    • pp.311-314
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    • 2009
  • This paper presents the characteristics of grounding impedance of counterpoises buried at various soil structures. Grounding impedance measurements were made by the Fall-of-Potential method. The experiments were carried out in 50 m counterpoise of 25 $mm^2$ buried at a depth of 0.5 m. The test current was injected by the impulse generator having the front time of $1{\sim}60{\mu}s$. As a result, the soil structures greatly influences on the grounding impedance characteristics of counterpoise. The transient grounding impedances strongly depend on the injection mint and the front time of impulse current.

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Earth Resistance Measurement Method by Clamp-one Type Current Comparison (클램프온식 전류비교 접지저항 측정방법)

  • Jeong, M.S.
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.353-355
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    • 2007
  • 피접지체의 접지는 전력설비의 절연파괴,낙뢰 등으로 전압이 침입할 경우 접지전극의 접지저항이 높으면 접지전극으로 유입되는 전류와 접지저항의 곱에 해당하는 접지전극의 전위가 상승하게 되므로 설비의 파손 인축의 피해 등이 발생 할 수 있다. 따라서 접지저항은 낮은 값으로 유지하는것이 필요하고 정기적으로 측정하여 관리하도록 규정하고 있다. 대표적인 접지저항측정방법으로는 3전극법(Fall of potential method)과 Hook-on 측정법이 있다. 그러나 3전극법은 측정하고자 하는 접지전극으로부터 일정한 거리에 전류를 흘려주고 이때 대지 전위를 측정 할 수 있는 2개의 보조전극 설치가 필수적이나 접지극과 접지선의 단자와는 설치 위치가 다르므로 접지전극의 설치점을 확인하기 곤란하고 건물내부, 지하철, 터널 등에는 보조전극의 설치가 거의 불가능하므로 처음 설치한 접지극의 접지저항측정관리에 어려움이 크다. 또한 Hook-on 측정법은 다중 접지 계통에 사용하는 방법으로 접지극이 수십 또는 수백개를 병렬로 연결한 경우 측정하고저 하는 접지그의 접지저항값에 비해 나머지 접지전극 전체의 합성저항이 무시할 수 있을 만큼 적은 경우에만 측정할 수 있으므로 건물이나 변전실 등 수개의 접지극이 설치된 경우는 사용할 수 없다. 본 연구는 보조전극을 설치하지 않고 측정하고자하는 접지전극 상호간의 전류분배 비율을 저항의 역수 비율로 하여 각각의 접지 전극의 접지저항값을 운전 중인 상태에서 간단하고 정확하게 측정할 수 있는 새로운 접지저항 측정 방법에 관한 연구이다.

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Complexity Comparison of Center of Pressure between Fallers and Non-fallers during Gait (보행 시 낙상 유무에 따른 압력중심점의 복잡성 비교)

  • Park, Sang Kyoon;Ryu, Sihyun;Kim, Jongbin;Yoon, Sukhoon;Ryu, Jiseon
    • Korean Journal of Applied Biomechanics
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    • v.29 no.2
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    • pp.113-119
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    • 2019
  • Objective: The purpose of this study was to investigate the effect of the falls on the center of pressure (CoP) complexity during gait using non-linear approximate entropy (ApEn). Method: 20 elderly women with experience of falling ($age=72.55{\pm}5.42yrs$; $height=154.40{\pm}4.26cm$; $body\;weight=57.40{\pm}6.21kg$; $preferred\;gait\;speed=0.52{\pm}0.17m/s$) and 20 elderly women with no experience of falling ($age=71.90{\pm}2.90yrs$; $height=155.28{\pm}4.73cm$; $body\;weight=56.70{\pm}5.241kg$; $preferred\;gait\;speed=0.56{\pm}0.13m/s$) were recruited for the study. While they were walking at their preferred gait speed on a treadmill (instrumented dual belt treadmills, Bertec, USA) with a force plate CoP data were collected for the 20 strides. The complexity of the CoP was analyzed using the ApEn technique. Results: The ApEn of the medial-lateral CoP in the fallers showed smaller about 16% compared to the non-fallers (p<.05). The ApEn of the antero-posterior CoP of the fallers showed smaller about 12% compared to the non-fallers, but the difference was not statistically significant. Conclusion: Based on the results of this study, the reduction of the medio-lateral CoP complexity in the elderly gait would be an index to determine the potential fall.

Temporary Work-intagration Social Eenterprise and Fiscal Consolidation in Germany - Focus on the Fall of the Community Gie${\ss}$en - (독일의 '경과적 일자리 중심 노동통합형 사회적기업'과 공공부문의 재정건실화 - 기이센(Landkreis Gie${\ss}$en)의 사례를 중심으로 -)

  • Park, Su-Sie
    • Korean Journal of Social Welfare
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    • v.62 no.2
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    • pp.187-208
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    • 2010
  • This Article attempts to analyse the enlarger phenomenon of 'temporary work-integration social enterprise' in 80's and 90's years in Germany. For this analysis were considered concepts and development of the 'secondary labour market' with respect of the 'temporary work-integration social enterprise'. At the same time were observed the background of the settlement of the 'secondary labour market' as local infrastructure for job creation in 80's and 90's years. Next was analyzed the contribution of the 'temporary work-integration social enterprise' on the fiscal consolidation through the method of cost-benefit analysis in fall of the community Gie${\ss}$en. Finally was limits and potential of the 'temporary work-integration social enterprise' analyzed, which as strategy for the fiscal consolidation was expanded in 80's and 90's years.

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Analysis on the Induction Effects by Separation Distance between the Power Feeding Station and the Telecommunication Cables (3점 전위강하법과 2극 측정법에 대한 접지저항 측정 결과 분석)

  • Choi, Mun-hwan;Lee, Snag-mu;Cho, Pyung-dong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.10a
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    • pp.577-580
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    • 2012
  • RRA Notification No.2010-36 suggests the 3-point method(fall-of-Potential) using 2 auxiliary poles only as a test method of earth resistance. However this method needs to much space to install auxiliary poles so it is very difficult to measure the earth resistance in spots such as a mountain district, rocky district. So, we have analyzed the methods of 2-point method and loop resistance method in IEEE std. 81 and ITU-handbook(Earthing and Bonding) and applied these methods in test bed with 3-point method. In this paper we have compared and analyzed the earth resistance value using these 3 methods.

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Determination of Electric Parameters of Cell Membranes Using Dielectrophoretic Levitation (Dielectrophoretic Levitation을 이용한 세포막의 전기적 특성 결정)

  • Kim, Yong-Wook;Lee, Sang-Wook;Lee, Sang-Hun;Kim, Yong-Kweon
    • Proceedings of the KIEE Conference
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    • 1994.07a
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    • pp.183-185
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    • 1994
  • A new method for determination of electric parameter of cell membranes is proposed. Two circular electrodes is designed to have repulsive force. From the potential energy analysis, stable points where a cell is levitated between electrodes exist and move as frequency or voltage change. The levitated cell in the stable point fall freely when DEP force is zero. The DEP force is dependent on the frequency and the force is zero at the critical frequency. The critical frequency is determined by measuring the difference between the time taken at zero-applied voltage and the time taken at the frequency and the voltage. For example, the critical frequency and stable points of N.crassa slime cell is numerically evaluated. In the exeriment, polystyrene in water is levitated at the stable point. We show that the stable point move as the applied voltage is changed.

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