• 대한임상독성학회지
• /
• 제18권2호
• /
• pp.116-122
• /
• 2020

Acute respiratory failure is an important risk factor for mortality in patients with acute pesticide poisoning. Therefore, it is necessary to investigate the risk factors to predict respiratory failure in these patients. This study retrospectively investigated the clinical features of respiratory failure among patients with acute pesticide poisoning requiring mechanical ventilation. This study included patients who were admitted with intentional poisoning by pesticide ingestion from January 2017 to December 2019. Paraquat intoxication was excluded. Among 469 patients with acute pesticide poisoning, 398 patients were enrolled in this study. The respiratory failure rate was 30.4%. The rate of respiratory failure according to the type of pesticide was carbamate (75.0%), organophosphate (52.6%), glufosinate (52.1%), glyphosate (23%), pyrethroid (8.9%), and others (17%). The mortality was 25.6% in the respiratory failure group. The risk factors for respiratory failure were old age, low body mass index, and ingestion of more than 300 mL. In conclusion, respiratory failure is a risk factor for mortality in pesticide poisoning. Old age, low body mass index, and ingestion of more than 300 mL are the risk factors for predicting respiratory failure.

• 한국가스학회지
• /
• 제4권2호
• /
• pp.37-45
• /
• 2000

지하에 매설되어 있는 도시가스배관은 부식성 없는 유체이기 때문에 화학플랜트배관보다는 상대적으로 안전하다. 그러나, 도시가스는 일반적으로 도심지역에 공급됨으로 공급지역의 여러 간섭시설물과 환경에 의한 부식과 시설물의 굴착공사로 야기되는 제 3자 사고등으로 큰 사고를 야기할 수 있다. 특히 지하매설된 배관이므로, 배관의 손상여부를 파악하고 검사하는 것이 상당히 난해하다. 따라서, 본 고에서는 지하매설배관의 위험성 개념을 도입하여, 위험지역 배관을 선정하여 관리하는 것으로 접근하였다. 여기서 위험성은 부식요인, 설계 및 시공요인, 유지관리요인으로 파악하여 나타내었고, 배관의 정성적인 위험성을 점수로 표현하여, 정량적인 숫자로 표현하였다. 또한 Key 인자 개념과 비용에 대한 손상보완대책 개념을 프로그램에 도입하여, 신뢰성과 안전경영에 도움이 되리라 생각된다. 본 위험성 평가 프로그램은 비쥬얼 베이직을 사용하여 개발하였고, GIS와 연계하였다.

• Archives of Pharmacal Research
• /
• 제10권4호
• /
• pp.245-249
• /
• 1987

Cardiovascular disease is at present the leading cause of deth in the United States and other in dustrilized countries. A major contributing factor of cardiovascular disease is essential hypertension. Untreated, essential hypertension is considered a risk factor for sudden death due to myocardial infarctions, as well as a risk factor for cerebral vascular disease, renal failure and congestive heart failure. During the last decade, significant progress has been made in the basic knowledge of the pathogenesis of hypertension as well as in the development of new antihypertensive drugs.

• 한국지반신소재학회논문집
• /
• 제17권4호
• /
• pp.53-64
• /
• 2018

본 연구에서는 안정성과 위험도 평가의 중요성이 증대되고 있는 DCM(Deep Cement Mixing, 이하 DCM) 보강 지반상의 항만 구조물에 대하여 위험도 평가를 위한 파괴확률을 산정하였다. DCM 개량 지반의 위험도에 영향을 미치는 확률변수로 개량체의 설계기준강도와 시공중첩, 원지반의 강도 및 내부마찰각, 개량지반의 단위중량을 선정하고 관련 통계치를 산정하여 적용하였다. 또한, 상시 조건과 지진시 조건에서의 전체 시스템에 대한 파괴확률을 분석하였다. 본 연구를 통해 DCM 개량지반의 위험도 평가를 위한 확률변수에서 변동계수가 가장 큰 것은 설계기준강도이나 안전율의 변동성 즉, 시스템의 위험도에는 큰 영향을 미치지는 않는 것을 알 수 있었다. DCM 보강 지반에 대한 시스템의 파괴확률 영향인자 즉, 주된 위험요소는 상시 및 지진시 모두 외적안정의 경우 수평활동, 내적안정의 경우 압축파괴인 것으로 평가되었다. 또한, 수평활동에 대해서는 상시 파괴확률이 지진시 파괴확률보다 높고 압축파괴에 대해서는 상시 파괴확률이 지진시 파괴확률보다 낮은 것으로 나타났다. 전체 시스템의 상시 파괴확률과 지진시 파괴확률은 유사하지만, 본 사례의 경우 지진시 위험도가 다소 높은 것으로 나타났다.

• 한국수소및신에너지학회논문집
• /
• 제31권1호
• /
• pp.65-72
• /
• 2020

In this study, the purpose is to identify the risks of the facilities of packaged hydrogen stations. As a risk identification method, failure mode & effect analysis (FMEA), a qualitative risk assessment, was used to analyze failure mode and effects of component of each facility. The analysis criteria were used to derive the risk priority number (RPN) using the 5-point method according to severity, incidence, and detectability. The study analyzed a total of 141 components of 23 types that can be identified on the design of the packaged hydrogen filling station. As a result, 683 types of failures and their causes and effects were identified. and the RPN was number of a total of 1,485. Of these, 10 failure types with a RPN value of 40 or more were deemed necessary. In addition, a list of failure types with a severity score of 5 was identified and analyzed.

• 한국지반공학회:학술대회논문집
• /
• 한국지반공학회 2008년도 추계 학술발표회
• /
• pp.893-903
• /
• 2008

A method for predicting surface failures which occur during heavy rainfall on mountain slopes is proposed by using the digital land form model that is obtained by reading altitude on a topographical map at 10m grid point space. A depth of a potential failure layer is assumed at each grid point. In the layer, an infiltrated water movement from cell to cell is modeled in the study (cell is a square of the grid). Infiltrated ground water levels which show the three dimensional effects of a topographical factor in an area can be hourly calculated at every cell by the model. The safety factor of every cell is also calculated every hour by the infinite slope stability analysis method with the obtained infiltrated ground water level. Failure potential delineation is defined here as the time when the safety factor becomes less than unity under the assumptions that effective rainfall is 20mm/h and continues 20 hours.

• 중환자간호학회지
• /
• 제12권1호
• /
• pp.94-108
• /
• 2019

Purpose : Heart failure (HF) is considered an important medical burden with rehospitalization and mortality. Anemia is a major risk factor associated with the severity of HF. To improve the understanding of the impact of anemia in the population with HF, we explored the prevalence of anemia, its guidelines, relationship between anemia and mortality or rehospitalization, and limitation of reviewed papers of various populations with HF. Method: We used Whittemore and Knafl's integrative review methodology (2005), and thirty research papers were analyzed. PubMed, CINAHL, Cochrane, PsychInfo, Embase, Web of Science were searched for papers published between January 1960-June 2018. Results: Anemia in individuals with HF was primarily defined using the World Health Organization guideline. The prevalence of anemia in patients with HF varied from 9% to 56.7%. Moreover, such a condition significantly increases the prevalence of mortality or rehospitalization in patients with HF. The analyzed majority were non-prospective cohort study including secondary data analysis. Conclusion: Anemia in individuals with HF is a significant risk factor of mortality and rehospitalization. Prospective cohort studies should be designed to identify the optimal value for screening anemia and the impact of anemia on rehospitalization and mortality among HF patients.

• Journal of Periodontal and Implant Science
• /
• 제50권6호
• /
• pp.379-391
• /
• 2020

Purpose: The aims of this study were to evaluate the 5-year cumulative survival rate (CSR) of implants placed with guided bone regeneration (GBR) compared to implants placed in native bone, and to identify factors contributing to implant failure in regenerated bone. Methods: This retrospective cohort study included 240 patients who had implant placement either with a GBR procedure (regenerated bone group) or with pristine bone (native bone group). Data on demographic features (age, sex, smoking, and medical history), location of the implant, implant-specific features, and grafting procedures and materials were collected. The 5-year CSRs in both groups were estimated using Kaplan-Meier analysis. Risk factors for implant failure were analyzed with a Cox proportional hazards model. Results: In total, 264 implants in the native bone group and 133 implants in the regenerated bone group were analyzed. The 5-year CSRs were 96.4% in the regenerated bone group and 97.5% in the native bone group, which was not a significant difference. The multivariable analysis confirmed that bone status was not an independent risk factor for implant failure. However, smoking significantly increased the failure rate (hazard ratio, 10.7; P=0.002). Conclusions: The 5-year CSR of implants placed in regenerated bone using GBR was comparable to that of implants placed in native bone. Smoking significantly increased the risk of implant failure in both groups.

• Membrane and Water Treatment
• /
• 제8권2호
• /
• pp.137-147
• /
• 2017

A water treatment utility in South Korea operates a large system of pressurized hollow fiber membrane (PHFM) modules. The optimal selection of membrane module for the full scale plant was critical issue and carried out using Risk-based Life Cycle Cost (RbLCC) analysis based on the historical data of operation and maintenance. The RbLCC analysis was used in the process of decision-making for replacing aged modules. The initial purchasing cost and the value at risk during operation were considered together. The failure of modules occurs stochastically depending on the physical deterioration with usage over time. The life span of module was used as a factor for the failure of Poisson's probability model, which was used to obtain the probability of failure during the operation. The RbLCC was calculated by combining the initial cost and the value at risk without its warranty term. Additionally, the properties of membrane were considered to select the optimum product. Results showed that the module's life span in the system was ten years (120 month) with safety factor. The optimum product was selected from six candidates membrane for a full scale water treatment facility. This method could be used to make the optimum and rational decision for the operation of membrane water purification facility.

• 한국압력기기공학회 논문집
• /
• 제10권1호
• /
• pp.51-55
• /
• 2014

Based on the results of Probabilistic Safety Assessment(PSA) for a Nuclear Power Plant (NPP), Common Cause Failure(CCF) events have been recognized as one of the main contributors to the risk. Also, the CCF data and estimation method used in domestic PSA models have been pointed out as an issue with respect to the quality. The existing method of MGL and non-staggered testing even widely used were considered conservative in estimating the safety and had a limited capability in uncertainty analyses. Therefore, this paper presents the CCF estimation using a new generic data source and Alpha factor method. The analyses showed that Alpha factor and staggered method are effective in estimating the CCF contribution and risk insights of reference plant. This method will be a common bases for the optimization of new design for the construction plants as well as for the updating of safety assessment on the operating nuclear power plants.