• 한국통신학회논문지
• /
• 제24권8B호
• /
• pp.1421-1425
• /
• 1999

ATM 망에서 노드나 링크에서의 장애발생 시 이를 복구하기 위한 방안에 관하여 연구하였다. 네트워크상의 각 노드들은 RCC(Routing Control Channel)을 이용하여 노드들간의 네트워크 상태 정보를 가진 NSE(Network State Element)를 교환함으로써 각각의 노드들은 네트워크내 자원에 대한 동일한 토폴로지 정보를 가지게 된다. 그러므로, 동적으로 변하는 네트워크 상태를 반영한 새로운 대체 경로를 소스노드에서 설정하는 기법을 제안한다. 이러한 방법을 적용한 결과 호 수락 제어(Connection Admission Control)단계에서의 호 설정(cell setup) 실패율을 크게 줄여 복구의 향상 및 메시지 수의 축소 그리고 트래픽을 감소시키면서 빠른 복구가 가능하였다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권7호
• /
• pp.4061-4066
• /
• 2013

The extranodal natural killer/T-cell lymphoma (ENKTL) shows high local or systemic failure rates when radiotherapy (RT) is taken as the primary treatment, suggesting a role for chemotherapy (CT) added to RT for this disease. However, the appropriate mode of combined modality therapy (CMT) has not been fully defined. A total of one hundred and twenty-one patients with ENKTL receiving sandwich CT with RT were reviewed between January 2003 and August 2012. The primary endpoints were the response rate, progression-free survival (PFS), overall survival (OS), and the relapse rate. After the initial CT, there were 84 (69.4%) patients in CR, 22 (18.2%) patients in PR, 9 (7.4%) patients in SD, and 6 (5%) patients in PD, respectively. At the end of RT, the CR, PR, SD, and PD rates for all patients were 90.9% (n=110), 1.7% (n=2), 4.1% (n=5), and 3.3% (n=4), respectively. After a median follow-up of 42.3 months (3.5~112.3 months), the 5-year PFS was 74.7% (95% CI 70.4%~79.0%), and 5-year OS was 77.3% (95% CI 67.9%~86.7%). Disease progression was documented in 25 (20.7%) patients. The rates of systemic failure, local failure, and regional failure were 18.2%, 5.8%, 1.7%, respectively. Twenty death events (16.5%) were observed for the entire group of patients (18 deaths related to PD). Furthermore, CR to the initial CT and low Korean Prognostic Index (KPI) can independently predict long PFS and OS. The sandwich CMT achieved an excellent outcome for localized ENKTL with acceptable toxicity. We recommend it can be applied as the optimal choice for localized ENKTL.

• Radiation Oncology Journal
• /
• 제14권1호
• /
• pp.33-39
• /
• 1996

목적 : 초기 자궁경부암은 수술과 방사선치료 모두 가능하며 결과도 비슷하다고 알려져있다. 이에 근치적 방사선치료를 받은 초기 자궁경부암 환자의 생존율, 실패율, 부작용등을 다른 결과와 비교하기 위하여 후향적 분석을 시행하였다. 대상 및 방법 : 근치적 방사선치료를 시행한 자궁경부암 IB 48명과 IIA 32명을 대상으로 하였다. 1985년 11월 부터 1993년 5월 까지 등록된 환자들로 최소 추적기간은 2년이었다. 외부전골반 방사선치료를 40-50Gy 시행후 3가지 다른 1회 조사량으로 고선량 강내치료를 시행후, 추적조사하여 생존율, 실패양상과 합병증등을 분석하였다. 결과 : 5년 생존율과 5년 무병 생존율은 각각 $72.3\%,\; 72.8\%$였으며 예후인자는 병기 병소의 크기, 병리조직 (선암), 방사선치료의 반응이었다. 19명의 치료실패가 있었으며 대부분 24개월이내에 발생하였다. Grade 2이상의 만성합병증은 방광이 $8.8\%$, 직장이 $15\%$, 모두 $17.5\%$ 였으며 발생율과 심한 정도는 강내치료 1회 조사량과 총 선량에 유의한 상관관계가 있었다. 결론 : 초기 자궁암의 방사선치료는 수술의 결과와 비슷하였으며 예후가 나쁜환자는 결과가 안좋아서 더 적극적인 치료방법이 필요하며 만성 합병증을 줄이기 위해서는 적절한 질 packing 등으로 주위조직의 방사선 피폭량을 줄이고 고선량 강내치료시 적절한 1회 조사량의 선택이 필요한 것으로 생각된다.

• Journal of the Korean Wood Science and Technology
• /
• 제39권4호
• /
• pp.333-343
• /
• 2011

백합나무(yellow poplar)는 기후변화의 주범인 이산화탄소의 흡수율이 매우 뛰어나고 오존흡수율도 뛰어나 저탄소 녹생성장 시대에 적합한 수종이다. 속성수인 백합나무는 구조용 부재로의 성능은 약간 부족하지만 가구재나 내장재, 합판용재 등 다양한 용도로 활용가능한 수종이다. 본 연구에서는 백합나무를 이용하여 대단면 스킨팀버를 개발하고 압축 성능을 평가하였으며 다양한 용도 개발을 위해 수치해석 모델을 개발하였다. 정각형 스킨팀버는 소재에 대해 56.3%의 잔존 강도를 보여서 우수한 성능을 나타내었으며 원통형 스킨팀버의 경우 잔존면적율이 25%임에도 불구하고 소재에 대해 50% 가까운 압축 성능을 나타내어 가구용 뿐만 아니라 대단면 재료로써 다양한 쓰임새가 가능함을 보여주었다. 정각형과 원통형 모두 Brooming or end rolling이 주요 파괴모드로 나타났으며 부분적으로 splitting 파괴 모드도 나타났다. 잔존면적률이 큰 정각형 스킨팀버의 압축성능이 원통형 스킨팀버보다 높게 나타났지만 두 집단간에 압축성능에 있어 통계적 유의성은 보이지 않아 사용자의 편의대로 혼용하여 활용 가능할 것으로 판단된다. 수치해석 모델은 실제 압축성능 실험과 상당히 유사한 결과를 보였다. 따라서 다양한 형태와 치수에 대한 수치해석 모델 적용을 통해 백합나무 스킨팀버의 다양한 용도 개발에 활용할 수 있을 것으로 기대된다.

• 대한두경부종양학회지
• /
• 제23권1호
• /
• pp.26-31
• /
• 2007

Background and Objectives：Microvascular free flap reconstruction has been revolutionized in last two decades, and became a standard option in the reconstruction of head and neck defects. We intended to review our experiences of 51 microvascular free flap for head and neck defects during 5-year period and to analyze the types of flaps according to primary sites, success and complication rates. Subjects and Methods：From Oct. 2001 through Dec. 2005, fifty one free flap reconstructions were performed in forty nine patients at ENT department of Soonchunhyang university bucheon hospital. Primary sites, pathology, T-stage, operative time, time interval of oral feeding, and various reconstructive factors such as recipient and donor vessels, free flap related complications, failure rates and salvage rates were retrospectively analyzed. The relation between complication rates and preoperative risk factors were statistically analyzed. Results：Methods of reconstruction were radial forearm free flap(RFFF)(n=28, 54.9%), anterolateral thigh free flaps(n=9, ALTFF)(17.6%), rectus abdominis free flap(n=7, RAFF)(13.7%), jejunal free flap(n=5, JFF)(9.8%), and miscellanous(n=2, 4.0%) in order. In free flap related complications, failure of free flap occurred in seven cases(13.7%) and pharyngocutaneous fistula occurred in five cases(9.8%) among fifty one free flaps. The overall success rate of free flaps was 86.3%. Salvage of free flaps was possible only one among eight cases(12.5%). In positive preoperative risk factor groups, failure of free flap was higher than in negative risk factor group. However, it was not statistically significant. Conclusion：We confirmed that free flap reconstructions are highly versatile and reliable options for use in the reconstruction of various soft tissue defects of the head and neck. Free flaps have gained great popularity given its versatility, ability for a two-team approach, and minimal donor site morbidity. However, complications related to microvascular surgery may be overcome by increased surgical experience and by intensive flap monitoring in early postoperative period.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권5호
• /
• pp.2101-2107
• /
• 2012

Treatment responses of $N_0$ stage nasopharyngeal carcinoma were firstly analyzed comprehensively to evaluate long term outcomes of patients and identify prognostic factors. A total of 610 patients with $N_0$ NPC, undergoing definitive radiotherapy to their primary lesion and prophylactic radiation to upper neck, were reviewed retrospectively. Concomitant chemotherapy was administrated to 65 out of the 610. Survival rates of the patients were calculated using the Kaplan-Meier method and compared by log-rank test. Prognostic factors were identified by the Cox regression model. The study revealed the 5-year and 10-year overall, disease-free, disease-specific, local failure-free, regional failure-free, locoregional failure-free and distant metastasis-free survival rates to be 78.7% and 66.8%, 68.8% and 55.8%, 79.9% and 70.4%, 81.2% and 72.5%, 95.8% and 91.8%, 78.3% and 68.5%, 88.5% and 85.5%, respectively. There were 192 patients experiencing failure (31.5%) after radiotherapy or chemoradiotherapy. Of these, local recurrence, regional relapse and distant metastases as the first event of failure occurred in 100 (100/610, 16.4%), 15(15/610, 2.5%) and 52 (52/610, 8.5%), respectively. Multivariate analysis showed that T stage was the only independent prognostic factor for patients with $N_0$ NPC (P=0.000). Late T stage (P=0.000), male (P=0.039) and anemia (P=0.007) were independently unfavorable factors predicting disease-free survival. After treatment, satisfactory outcome wasgenerally achieved in patients with $N_0$ NPC. Local recurrence represented the predominant mode of treatment failure, while T stage was the only independent prognostic factor for overall survival. Late T stage, male gender, and anemia independently predicted lower possibility of the disease-free survival.

• Journal of Chest Surgery
• /
• 제22권6호
• /
• pp.980-989
• /
• 1989

The Hancock porcine xenograft valves had been used in Seoul National University Hospital, mainly because of their antithrombogenicity despite of the predicted failure, from March 1976 to April 1984, and a total and consecutive 163 patients were retrospectively studied for late results with the special stress on the structural failure. The hospital mortality rate [within 30 days] was 6.1 %, and the 153 early survivors were followed up for a total of 822.9 patient-years [p-y][Mean * SD 5.38 * 3.02 years]. The linealized late mortality was 1.823%/p-y. Four major complications related to the Hancock valve were: 1.822% thromboembolism/p-y; 0.729 % bleeding/p-y; 0.972% endocarditis/p-y; 3.646% overall valve failure/p-y and 2.187 % primary tissue failure [PTF]/p-y. The actuarial survival rates at 5 and 10 years were 94.90 * 1.89% and 80.58 * 5.21 %; and the probabilities of freedom from thromboembolism at 5 and 10 years were 90.93 * 2.63% and 83.35 * 7.64 9o respectively. The probabilities from PTF at 5, 10 and 12 years were 98.02 * 1.39%, 60.62 * 8.89% and 49.60 * 12.34 %. One hundred-eighteen patients [72.4%] had single MVR [age, 34.0 * 10.9 years] with the operative mortality rate of 4.2%; and 113 early survivors were followed up for a total 616.4 patient-years[5.46 * 2.96 years]. The late mortality rate was 1.460 %/p-y. The major complications were: 1.622 % thromboembolism /p-y; 0.487% bleeding/p-y; 0.649 % endocarditis/p-y; 2.920% primary valve failure/p y and 1.785% PTF/p-y. The actuarial survival rates were 97.08 * 1.67%[at 5 years] and 81.27 * 6.64%[at 10 years], and the probabilities of freedom from thromboembolism 92.44 * 2.76 %[at 5 years] and 80.89 * 11.08%[at 10 years]. The probabilities of freedom from PTF at 5 and 10 years were 98 70 * 1.29% and 65.59 * 9.78% respectively. The mean age of 11 patients of PTF was 25.7 * 8.8 years and the valve extraction period 7.16 * 1.45 years. Failure of bioprosthetic xenograft valves are reportedly known to occur earlier in young patients in an accelerated fashion. The study with two groups divided into the cumulative younger and the cumulative older patients according to the age limits of 5-year interval strongly suggested these tendency. Although PTF began to occur past postoperative 5 years and the probabilities of freedom from PTF increased as the age limits raised and the number of patients increased in the cumulative younger patients while they decreased as the age limits lowered and the number of patients increased in the cumulative older patients, the definite age limits from which the Hancock valve can be safely recommended could not be obtained. From the results, the Hancock valves are contraindicated in patients younger than 20 to 25 years and may be safely recommended in patients older than 45 years as a tentative conclusion. Further longitudinal study may define these age factors.

• 대한두경부종양학회지
• /
• 제21권1호
• /
• pp.26-31
• /
• 2005

Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.

• 전기전자학회논문지
• /
• 제9권2호
• /
• pp.143-151
• /
• 2005

본 연구에서는 유한고장 비동질적인 포아송 과정 모형에서 결함당 고장 발생률이 상수이거나, 단조 증가 또는 단조 감소하는 패턴을 가질수 있다. 감마족 분포를 적용하여 고장발생률에 대한 특징을 알아보았고 감마족 분포는 형상 모수의 선택에 따라 다양한 모형으로 유도 될 수 있다. 따라서 본 연구는 형상모형에 근거한 감마 또는 와이블 그리고 곰페르츠 모형을 제시하여 신뢰도 분석 결과를 나열하였고 모형 선택 및 자료 분석을 위하여 산술과 라플라스 검정과 편차 자승합 등을 이용하였다.

• 한국안전학회지
• /
• 제32권1호
• /
• pp.41-46
• /
• 2017

In this paper, from making an electrical fire which is thought to be the most damaging among potential dangers as a top event, minimal cut sets (MCS) about it were analyzed. For this, components of a power substation were classified into 15 items. Failure rates and modes were extracted based on Korea Electrical Safety Corporation, IEEE Gold Book, and RAC. To analyze the top event (an electrical fire), main events were assorted into "safety devices for overcurrent" and "ampere meter of detecter". Failure of components was divided into failure of VCB, COS, and MCCB. A fault tree was composed of 3 AND gate, 5 OR gates and 17 basic events. Overlapped events among the basic events are things which occur from relevant components. They were attached to the tree by distinguishing identifiers. In case of FT, two minimal cut sets of "IO_METER", "MF_METER", "DO_MCCB" and "IO_METER", "MF_METER", "DO_VCB" take 46% of electrical fires. Therefore, about basic events which are included in the top two minimum cut sets, strict control is necessary.